KEGG   Mycobacterium leprae Br4923: MLBr01705
Entry
MLBr01705         CDS       T00842                                 
Symbol
ligA
Name
(GenBank) DNA ligase
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
mlb  Mycobacterium leprae Br4923
Pathway
mlb03030  DNA replication
mlb03410  Base excision repair
mlb03420  Nucleotide excision repair
mlb03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:mlb00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    MLBr01705 (ligA)
   03410 Base excision repair
    MLBr01705 (ligA)
   03420 Nucleotide excision repair
    MLBr01705 (ligA)
   03430 Mismatch repair
    MLBr01705 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:mlb03032]
    MLBr01705 (ligA)
   03400 DNA repair and recombination proteins [BR:mlb03400]
    MLBr01705 (ligA)
Enzymes [BR:mlb01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     MLBr01705 (ligA)
DNA replication proteins [BR:mlb03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     MLBr01705 (ligA)
DNA repair and recombination proteins [BR:mlb03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     MLBr01705 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     MLBr01705 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     MLBr01705 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      MLBr01705 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT DNA_ligase_ZBD HHH_5 Nlig-Ia PTCB-BRCT HHH
Other DBs
NCBI-ProteinID: CAR71800
UniProt: B8ZS27
LinkDB
Position
complement(2055671..2057755)
AA seq 694 aa
MSSPEADPIGPEVLQQWRKLTEEVREHQFRYYVRDAPIISDAEFDALLDRLTVLEEQHPE
LCTPDSPTQLVGGAGFMTDFVATEHLERMFSLDNAFSGDELNAWVTRIRAEIGNDAHYLC
ELKIDGVALSLVYRDGRLTRATTRGDGRTGEDVTLNARTIEDVPERLTVSDIYPLPEVLE
VRGEVFFRVVDFQALNTSLVEEGKNPFANPRNSAAGSLRQKDPAVTAHRKLRMICHGLGH
IEGFRPATQHQAYLALRDWGLPVSEHTTLVNDIAGVQGCIAYWAEHRHEVDHEIDGIVVK
IDEVTLQRRLGSTSRAPRWAIAYKYLPEEAQTKLLDIRVNVGRTGRVTPFAFMTPVKVAG
STVGQATLHNPSEVKRKGVLIGDTVVIRKAGDVIPEVLGPVVDLRDGSEREFVMPTTCPE
CGTTLAPEKEGDADIRCPNARSCPGQLRERVFHVASRSALDIQGLGYEAGVALLAAQVIT
SEGDLFTLTEKALLRTELFRNKAGELSANGKRLLVNVDKAKTAPLWRVLVALSIRHVGPT
AARALATEFGSVDAILAASPEQLAAVEGVGTTIAAAVTEWFTVDWHRVIVNKWRAAGVRM
VDERDTSVLPTCEGLTIVVTGSLAGFSRDDAKEAIVARGGKVAGSVSKKIAYVVVGDLPG
YKYDKAVELGVPILNEDGFRLLLEQGPPVQQVVD
NT seq 2085 nt   +upstreamnt  +downstreamnt
gtgagttcccccgaagctgaccctatcggacccgaggtgttgcagcagtggcgaaagctg
accgaagaggtgcgtgaacaccagttccgttactatgtgcgtgacgcgccgatcatctct
gacgcggagtttgatgctctgctggacaggctcactgtgctggaggaacagcatcccgag
ctgtgcacgcccgattcacctacccagctggtcggcggtgctggcttcatgactgatttc
gtggcgaccgagcatctcgaacggatgttcagcctcgacaacgccttcagtggggatgaa
ctcaatgcctgggtcactcgcatccgcgcagagatcggtaatgacgcccattatttgtgt
gagctcaagatcgacggtgtcgcattgtcgttggtctaccgggatggacgcctgacccgc
gccacgactcggggcgatggtcgcaccggcgaagacgtcacgctgaacgcgcggaccatc
gaagatgtgccggaacggctgaccgtcagcgatatttacccgctgccagaggttcttgag
gtccgcggcgaggtgttcttccgagtggtggactttcaagcgcttaacacgagcctcgtt
gaggagggcaagaatccgttcgctaacccacgaaacagcgcggcgggctcgctgcgccag
aaggatccggcggtcacggctcaccgtaaactgcgaatgatctgtcatggactggggcac
atcgaaggctttcgtcccgctacccagcatcaggcttacttagctttacgggactggggg
ttgccggtgtccgagcatacgacgctggtcaacgacatagctggcgtccagggatgcatc
gcatactgggccgaacatcgtcacgaggtggaccatgaaatcgacgggatagtggtcaaa
atcgacgaggttacgttgcagcgcaggctgggttccacctcgcgagctccacgatgggcc
atcgcttacaagtacctacccgaggaggcgcagaccaagctgctcgacatccgggtgaac
gtcggccgcaccggtcgggttacgccattcgcgttcatgacgcccgtgaaagttgccggg
tcgacggtcgggcaggcgaccttgcacaacccttctgaggtcaaacgcaaaggtgtgctg
atcggtgacaccgtggtgatccgcaaggccggcgacgtgattcccgaagttttgggacct
gtggttgacttgcgcgacgggtccgaacgtgaatttgtgatgcccacaacgtgtcccgag
tgcggtactacgttagcgccagaaaaggaaggcgatgccgacatccgttgccccaatgcc
aggagctgcccggggcaactgcgagagcgagtgtttcacgtcgctagccgcagcgctctg
gacattcaggggttgggttacgaggccggtgtggcgttgctggctgcgcaagtgatcact
agcgagggcgacctgttcaccctcaccgagaaggccttgttgcgcaccgagcttttccgc
aacaaggcaggggagttgtcggcgaatggcaaacggttgctagtcaacgtcgacaaagcc
aaaactgcaccgctgtggcgagtgctggtggcgttgtcgatccggcatgtcgggccgacg
gctgcgcgagccttggccaccgagttcggcagcgttgacgcaatcttggccgcgtcccct
gaacaactggccgctgtcgagggtgtagggaccaccatcgcggccgcggttaccgagtgg
ttcaccgtcgactggcatcgcgtgattgtcaataagtggcgggctgccggggtgcggatg
gtcgatgagcgtgacaccagcgtgctgcccacatgcgaagggttgaccatcgtggtcact
ggttctttagcagggttttcccgtgacgatgccaaggaggcgatcgtggcgcgcggaggc
aaggtcgctggttcggtatcgaagaagatcgcctacgtggtcgtaggcgacttgccggga
tacaaatatgacaaggcggtcgagctcggggtgccgatcctcaacgaggacgggtttcgc
ctgttgcttgagcagggacctccggtgcagcaagtcgttgactag

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