Mycobacterium leprae TN: ML1095
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Entry
ML1095 CDS
T00047
Symbol
odhA
Name
(GenBank) 2-oxoglutarate dehydrogenase, E1 and E2 components
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mle
Mycobacterium leprae TN
Pathway
mle00020
Citrate cycle (TCA cycle)
mle00630
Glyoxylate and dicarboxylate metabolism
mle00785
Lipoic acid metabolism
mle01100
Metabolic pathways
mle01110
Biosynthesis of secondary metabolites
mle01120
Microbial metabolism in diverse environments
mle01200
Carbon metabolism
mle01210
2-Oxocarboxylic acid metabolism
Module
mle_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mle_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mle00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
ML1095 (odhA)
00630 Glyoxylate and dicarboxylate metabolism
ML1095 (odhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
ML1095 (odhA)
Enzymes [BR:
mle01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
ML1095 (odhA)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
ML1095 (odhA)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
ML1095 (odhA)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
ML1095 (odhA)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
CAC31476
Pasteur:
ML1095
UniProt:
Q9CC97
LinkDB
All DBs
Position
complement(1260028..1263810)
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AA seq
1260 aa
AA seq
DB search
MQKVASVAQCACRTEELRRTAAVANISSPFGQNEWLVEEMYRKFRDDPSSVDPSWHEFLV
DYNPESTAEPVLTDPTSTDKQPSATPQAKPAAAADPVASRAKPATTPTVANGTAAGSAAA
PAKTTTTPPIEGDELQVLRGAAAVVVKNMSASLDVPTATSVRAVPAKLMIDNRTVINNQL
KRNRGGKISFTHLLGYALVQAVKKFPNINRHYAEIDGKPIAVTPAHTNLGLAIDLQGKDG
KRSLVVAGIKRCEELRFAQFVTAYEDIVRRARDGKLTAEDFAGVTISLTNPGTIGTVHSV
PRLMTGQGAIIGVGAMEYPAEFQGASAERIAELGIGKLITLTSTYDHRIIQGAESGDFLR
TIHEMVLSDSFWDEIFRELSIPYLPVRWRTDNPDSIVDKNARVMELIAAYRNRGHLMADI
DPLRLDNTRFRSHPDLDLLTHGLTLWDLDRVFKVNGFGGWKYKKLRDVLGLLRDAYCRHI
GVEYTHILDPEQQEWLQQRVETKNVKPTVAEQKYILSKLNAAEAFETFLHTKYVGQKRFS
LEGAESVIPMMDAAIDQCAKHGLDEVVIGMPHRGRLNVLANIVGKPYSQIFTEFEGNLNP
TLAHSSGDVKYHLGATGLYLQMFGDNDIQVSLTANPSHLEAVDPVLEGLVRAKQDLLNKD
TNGNQDEAFSVVPMMLHGDAAFAGQGVVAETLNLANLPGYRVGGTIHIIVNNQIGFTTAP
EYSRSSEYCTDVAKMIGAPIFHVNGDDPEACVWVAKLAVDFRQRFKKDVVIDMLCYRRRG
HNEGDDPSMTNPYMYDVVDTKRGARKSYTEALIGRGDISLKEAEDALRDYQGQLERVFNE
VRDLEKHGVQPSESVESDQMIPAGLSTAVDKALLARIGDAFLAVPEGFTVHPRVQPVLEK
RREMAYEGKIDWAFAELLALGSLVAEGKLVRLSGQDTKRGTFSQRHSVIIDRHTGEEFTP
LQLLANNPDGSPTGGKFLVYNSPLSEYAAVGFEYGYTVGNPDAVVLWEAQFGDFVNGAQS
IIDEFINSGEAKWGQLSTVVLLLPHGHEGQGPDHTSGRIERFLQLWAEGSMTFAVPSTPS
NYFHLLRRHALDGIKRPLIVFTPKSMLRNKAAVSDIKDFTEIKFRSVLEEPTYEDSIDDR
SKVTRVLLTCGKLYYELAARKIKDNRDDVAIVRIEQLAPLPRRRLGETLDRYENAKEFFW
VQEEPANQGAWPRFGLELPELLPRLTGIKRISRRAMSAPSSGSSKVHAVEQQEILDTAFG
NT seq
3783 nt
NT seq
+upstream
nt +downstream
nt
gtgcagaaagttgcaagtgtcgcgcaatgcgcttgcaggacagaagaattgaggcgaaca
gcggccgtggccaacataagttcaccattcgggcaaaacgaatggttggtcgaagagatg
taccgcaagttccgcgacgacccctcctcggtcgatccgagctggcacgaattcctggtt
gactacaatcccgaatcaaccgccgaaccggtacttacggaccctacctccactgataaa
caaccctcagccacgccacaagcaaagccagctgcggcagctgacccggtagcgagcagg
gccaagcccgcgaccaccccaacagtagcgaacggcacggcagccggctctgccgcagct
ccagccaaaaccaccactaccccgcctatcgaaggtgacgagttgcaggtgctgcgcggt
gccgccgcagtggtcgtcaaaaatatgtccgcgtcgctggacgtgccgacggcgaccagt
gtgcgagccgttccagccaagctgatgatcgacaaccggaccgtcatcaacaaccagctc
aagcgcaaccgcggcgggaagatctccttcacgcatttgctgggctacgcgttagtgcag
gcggtcaagaagttcccgaacatcaaccggcactacgcggagatcgacggcaaacccatc
gcagtgacaccggcccacaccaatctcggcctagcgatcgacctgcaaggtaaagacggc
aagcggtccttggtggtggccggtatcaagcgctgcgaagaattgcgattcgcacagttc
gtcaccgcctacgaagatatcgtccgccgggcgcgcgacggtaagctgaccgccgaagac
tttgccggcgtcacgatttcacttaccaaccccggcactatcggcaccgtgcattcggtg
ccgcggctgatgactggccagggcgccatcatcggcgtgggcgccatggaataccccgcc
gagtttcaaggcgccagcgcggagcgcatcgccgaattgggtatcggcaaactgatcacc
ctaacttcaacctacgaccaccgcatcatccagggtgcggaatcaggtgacttcctgcgc
acgatccacgaaatggtgctctcggacagcttctgggacgaaatctttcgcgagctgagc
atcccgtatctgccggtgcgctggcgcaccgacaacccggactcgatcgtcgacaagaac
gctcgcgtcatggagttgatcgcggcctaccgtaaccgcggccatctaatggccgatatc
gacccgctgcggttggacaacacccgcttccgcagtcaccctgacctcgatttgctaacc
cacggcctgacgctgtgggatctggatcgggtattcaaagtcaacggctttggcgggtgg
aaatacaagaaactgcgtgacgtgctgggcttgcttcgcgacgcctactgccgccacatc
ggcgtggaatacacccacatcctcgaccccgaacaacaggaatggctgcaacagcgggtc
gagaccaagaacgtcaaaccgactgtggccgaacagaaatacatcctgagcaagctcaac
gctgccgaagccttcgaaacgttcctgcatactaagtacgtcgggcagaaacgtttctcg
ctagaaggcgccgaaagcgttatcccgatgatggatgcggcgatcgaccagtgcgccaag
catggcctggacgaagtggtcatcgggatgccacaccgcggccggctcaacgtattggcc
aacatcgtcggcaagccgtactcacagatcttcaccgaattcgagggcaatctaaaccca
acactagcgcacagctctggtgacgtcaaataccacctcggtgctaccggtttgtatctg
cagatgttcggcgacaacgacattcaagtatcgctgaccgccaacccttcacacttggaa
gccgtggaccccgtgctcgaaggtctcgtccgggccaagcaggatctactcaacaaggat
accaatggcaaccaagatgaagcgttttcggtggtgccaatgatgctgcacggggacgct
gccttcgccggccaaggagtcgttgccgaaacgctaaacttggcgaacctgcctggttac
cgggtcggcggcaccatccacatcatcgtcaacaaccagatcggcttcactaccgcgccg
gagtactccagatccagcgagtactgcacggatgtcgccaagatgatcggcgcgccgatc
ttccacgtcaacggtgatgacccggaagcctgcgtgtgggtagccaagctggcggtcgac
tttcggcagcgttttaaaaaggacgtcgttatcgacatgctgtgctaccgccggcgcggg
cacaatgagggcgacgatccgtcgatgacgaacccgtacatgtacgacgttgtcgacacc
aagcgcggcgcccgtaagagttacaccgaagccttgatcggccgtggcgacatttccttg
aaggaagccgaggacgcgctgcgcgactaccaaggccagctggagcgggtgttcaacgag
gtacgcgacctggaaaagcacggcgtgcagcccagcgagtcagtggagtctgaccagatg
atccctgcgggtttgtccaccgcggtggacaaagcactgctggcccgcatcggcgacgcc
ttcctggcggtaccagaaggtttcaccgtgcacccgcgggtgcagccggtgctcgagaaa
cgccgggagatggcttatgaaggcaagatcgactgggctttcgccgagttgctagcctta
gggtcgctggtggcggaaggcaaattggtgcggctgtccggccaagacaccaagcgtggc
accttctcgcagcggcattcggtgatcatcgaccgccacaccggcgaggaattcactccg
ttacagctgctggccaataaccccgacggcagtcccaccggcggcaagtttctggtctac
aactcgccactgtcggagtatgccgctgtcggtttcgagtacggctatacggtaggcaac
ccggatgccgtggtgctgtgggaggcgcagttcggcgacttcgtcaacggcgcacagtca
atcatcgacgaattcatcaactccggtgaggccaagtggggacagttgtcgacagtggtg
ctgctattgccgcacgggcacgaagggcagggccctgaccacacctctggccgcatcgaa
cgcttcctgcagctgtgggcggagggctcaatgacctttgcggtgccgtcgactccatct
aactacttccacttgctgcgccggcacgctctcgacggcattaaacgtccactgatcgtg
ttcacgcccaagtcgatgttgcgcaacaaggccgcagtcagtgatatcaaggacttcacc
gagatcaagttccgttcggtgctggaggaacccacctacgaggacagcatcgacgaccgc
agcaaggtcaccagggtcctgttgacctgcggcaagctctactacgagctggccgcccgc
aagatcaaggacaaccgcgacgacgtcgcgatcgtgcggatcgaacagctggccccgctg
ccgcggcgccggctcggcgaaacgctggaccgctacgagaacgccaaagagttcttctgg
gtgcaagaggagccagccaatcaaggtgcctggccgcggttcggcctggagctgcccgag
ctgctgccccgactcaccgggatcaagaggatttcgcggcgggccatgtcggcgccgtcg
tcgggttcgtcgaaggtgcatgccgtcgagcaacaggagatcctcgacaccgcgttcggc
taa
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integrated database retrieval system
