KEGG   Mammaliicoccus lentus: H3V22_04770
Entry
H3V22_04770       CDS       T07021                                 
Symbol
dfrG
Name
(GenBank) trimethoprim-resistant dihydrofolate reductase DfrG
  KO
K18591  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
Organism
mlen  Mammaliicoccus lentus
Pathway
mlen00670  One carbon pool by folate
mlen00790  Folate biosynthesis
mlen01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:mlen00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    H3V22_04770 (dfrG)
   00670 One carbon pool by folate
    H3V22_04770 (dfrG)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes [BR:mlen01504]
    H3V22_04770 (dfrG)
Enzymes [BR:mlen01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     H3V22_04770 (dfrG)
Antimicrobial resistance genes [BR:mlen01504]
 Gene variants
  Trimethoprim resistance genes
   Dihydrofolate reductases
    H3V22_04770 (dfrG)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: QMU11511
LinkDB
Position
complement(938156..938653)
AA seq 165 aa
MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILGRKNLESIGRALPDRRN
IILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIYNLFFPYVEKMYITKIHHE
FEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYERKNLLS
NT seq 498 nt   +upstreamnt  +downstreamnt
atgaaagtttctttgattgctgcgatggataagaatagagtgattggcaaagagaatgac
attccttggaggattcccaaggactgggaatatgttaaaaatactacaaagggacatccg
ataatattaggtaggaagaaccttgaatcaatcggaagagccttacctgacagaagaaat
attattctgacgagagataaggggtttacctttaatggttgtgaaattgttcattcaata
gaagatgtttttgagttatgtaaaaacgaagaagaaatttttattttcggaggagaacag
atttataatttgtttttcccttatgttgagaaaatgtacatcacaaaaatacatcatgaa
ttcgaaggagatactttttttccagaagtgaattatgaggaatggaatgaggtatttgcc
caaaaagggataaagaatgataaaaatccgtataactactattttcatgtatatgaaaga
aaaaacttattgagttaa

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