Mandrillus leucophaeus (drill): 105528513 Help Entry 105528513         CDS       T08763                                  Symbol ROCK2 Name (RefSeq) rho-associated protein kinase 2   KO K17388   Rho-associated protein kinase 2 [EC:2.7.11.39] Organism mleu  Mandrillus leucophaeus (drill) Pathway mleu04022   cGMP-PKG signaling pathway mleu04024   cAMP signaling pathway mleu04062   Chemokine signaling pathway mleu04071   Sphingolipid signaling pathway mleu04270   Vascular smooth muscle contraction mleu04310   Wnt signaling pathway mleu04360   Axon guidance mleu04510   Focal adhesion mleu04520   Adherens junction mleu04530   Tight junction mleu04611   Platelet activation mleu04670   Leukocyte transendothelial migration mleu04810   Regulation of actin cytoskeleton mleu04921   Oxytocin signaling pathway mleu05132   Salmonella infection mleu05135   Yersinia infection mleu05163   Human cytomegalovirus infection mleu05200   Pathways in cancer mleu05205   Proteoglycans in cancer mleu05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mleu00001]  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     105528513 (ROCK2)    04071 Sphingolipid signaling pathway     105528513 (ROCK2)    04024 cAMP signaling pathway     105528513 (ROCK2)    04022 cGMP-PKG signaling pathway     105528513 (ROCK2)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     105528513 (ROCK2)    04520 Adherens junction     105528513 (ROCK2)    04530 Tight junction     105528513 (ROCK2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     105528513 (ROCK2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     105528513 (ROCK2)    04670 Leukocyte transendothelial migration     105528513 (ROCK2)    04062 Chemokine signaling pathway     105528513 (ROCK2)   09152 Endocrine system    04921 Oxytocin signaling pathway     105528513 (ROCK2)   09153 Circulatory system    04270 Vascular smooth muscle contraction     105528513 (ROCK2)   09158 Development and regeneration    04360 Axon guidance     105528513 (ROCK2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105528513 (ROCK2)    05205 Proteoglycans in cancer     105528513 (ROCK2)   09172 Infectious disease: viral    05163 Human cytomegalovirus infection     105528513 (ROCK2)   09171 Infectious disease: bacterial    05132 Salmonella infection     105528513 (ROCK2)    05135 Yersinia infection     105528513 (ROCK2)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     105528513 (ROCK2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mleu01001]     105528513 (ROCK2)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:mleu03036]     105528513 (ROCK2) Enzymes [BR:mleu01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.39  ROCK-subfamily protein kinase      105528513 (ROCK2) Protein kinases [BR:mleu01001]  Serine/threonine kinases: AGC group   DMPK family [OT]    105528513 (ROCK2) Chromosome and associated proteins [BR:mleu03036]  Eukaryotic type   Centrosome formation proteins    Kinases and associated factors     105528513 (ROCK2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr Rho_Binding PH C1_1 Pkinase_C APH Irp3-like_C Motif Other DBs NCBI-GeneID:  105528513 NCBI-ProteinID:  XP_011820672 Ensembl:  ENSMLEG00000029001 LinkDB All DBs Position Unknown AA seq 1302 aa AA seqDB search MKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAF ANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEVVLALDAIH SMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQG GDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAK NLICAFLTDREVRLGRNGVEEIRQHPFFKNDQWHWDNIRETAAPVVPELSSDIDSSNFDD IEDDKGDVETFPIPKAFVGNQLPFIGFTYYRENLLLSDSPSCRENDSIQSRKNEESQEIQ KKLYTLEEHLSSEIQAKEELEQKCKSVNTRLEKTAKELEEEITLRKSVESALRQLEREKA LLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNSQISTEKVNQLQRQLDE TNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSA LESERRDRTHGSEIINDLQGRISGLEEDLKNGKILIAKVELEKRQLQERFTDLEKEKSNM EIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTL KQKVENLLLEAEKRCSILDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLT QNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQL EAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQ LARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLA NEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNRKE PVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQMIKYQKELNEMQAQIAEESQIRIELQ MTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPGDAEADDGFPESRLEGWLSLPARNNTK KFGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVLDIDKLFHVRPVTQTDVYRADAKEIPR IFQILYANEGESKKEQEFPVEPVGEKSNYICHKGHEFIPTLYHFPTNCEACMKPLWHMFK PPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYDISTAKNLLLLANSTEEQQKWVSRLVK KIPKKPPAPDPFARSSPRTSMKIQQNQSIRRPSRQLAPNKPS NT seq 3909 nt NT seq  +upstreamnt  +downstreamnt atgaaggcagaagactatgatgttgtaaaagttattggaagaggtgcttttggtgaagtg cagttggttcgtcataaggcatcacagaaggtttatgctatgaagcttcttagtaagttt gaaatgataaaaagatcagattctgcctttttttgggaagaaagagatattatggccttt gccaatagcccctgggtggttcagcttttttatgcctttcaagatgataggtatctgtac atggtaatggagtacatgcctggtggagaccttgtaaaccttatgagtaattatgatgtg cctgaaaaatgggccaaattttacactgctgaagttgttcttgctctggatgcaatacac tctatgggtttaatacacagagatgtgaagcctgacaacatgctcttggataaacatgga catctaaaattagcagattttggcacgtgtatgaagatggatgaaacaggcatggtacat tgtgatacagcagttggaacacctgattatatatcacctgaggttctgaaatcacaaggg ggtgatggttactatgggcgagaatgtgattggtggtctgtaggtgttttcctttttgag atgctagtgggggatactccattttatgcggattcacttgtaggaacatatagcaaaatt atggatcataagaattcactgtgtttccctgaagatgcagaaatttccaaacatgcaaag aatctcatctgtgctttcttaacagatagggaggtacgacttgggagaaatggggtagaa gaaatcagacaacatcctttctttaagaatgatcagtggcattgggataacataagagaa acggcagctcctgtagtacctgaactcagcagtgacatagacagcagcaatttcgatgac attgaagatgacaaaggagatgtagaaaccttcccaattcctaaagcttttgttggaaat cagctgcctttcataggatttacctactatagagaaaatttattattaagtgactctcca tcttgtagagaaaatgattcaatacaatcaaggaaaaatgaagaaagtcaagagattcag aaaaaactgtatacattagaagaacatcttagcagtgagatacaagccaaagaggaactg gaacagaagtgcaaatctgttaatactcgcctagaaaaaacagcaaaggagctagaagag gagattaccttaaggaaaagtgtggaatcagcattaagacagttagaaagagaaaaggcg cttcttcagcacaaaaatgcagaatatcagaggaaagctgatcatgaagcagacaagaaa cgaaatttggaaaatgatgttaacagcttaaaagatcaacttgaagatttgaaaaaaaga aatcaaaactctcaaatatccactgagaaagtgaatcaactccagagacaactggatgaa accaatgctttactgcgaacagaatctgatactgcagcccggttaaggaaaacccaggca gaaagttcaaaacagattcagcagctagaatctaacaatagagatctacaagataaaaac tgcctgctggagactgccaagttaaaacttgaaaaggaatttatcaatcttcagtcagca ctagaatctgaaaggagggatcgaacccatggatcagagataattaatgatttacaaggt agaatatctggcctagaagaagatttaaagaacggcaaaatcttaatagcgaaagtagaa ctggagaagagacaactgcaggagagatttactgatttggaaaaggaaaaaagcaacatg gaaatagatatgacataccaactaaaagttatacagcagagcctagaacaagaagaagct gaacataaggccacaaaggcacgactagcagataaaaataagatctatgagtccatcgaa gaagccaaatcagaagccatgaaagaaatggagaagaagctcttggaggaaagaacttta aaacagaaagtggagaacctattgctagaagctgagaaaagatgttctatattagactgt gacctcaaacagtcacagcagaaaataaatgagctccttaaacagaaagatgtgctgaat gaggatgttaggaacctgacgttaaaaatagagcaagaaactcagaagcgctgccttaca caaaatgacctgaagatgcaaacacaacaggttaacacactgaaaatgtcagaaaagcag ttaaagcaagaaaataaccatctcatggaaatgaaaatgaacttggaaaaacaaaatgct gaacttcgaaaagaacgtcaggatgcagatgggcaaatgaaggagctccaggatcagctc gaagcagaacagtatttctcaaccctttataaaacacaagttagggagcttaaagaagaa tgtgaagaaaagaccaaacttggtaaagaattacagcaaaagaaacaggaattacaggat gaacgggactctttggctgctcaactggagatcaccttgaccaaagcagattctgagcaa ctggctcgttcaattgctgaagaacaatattctgatttggaaaaagagaagatcatgaaa gagctggagatcaaagagatgatggctagacacaaacaggaacttaccgaaaaagatgcc acaattgcttctcttgaagaaactaataggaccctaactagtgatgttgccaatcttgca aatgagaaagaagaattaaataacaagctgaaagatgttcaagagcaactgtcaagattg aaagatgaagaaataagcgcagcagctattaaagcacagtttgagaaacagctgttaaca gaaagaacactcaaaactcaagctgtgaataagttggctgagatcatgaatcgcaaagaa cctgtcaagcgtggtaatgacacagatgtgcggagaaaagagaaggagaatagaaagcta catatggagcttaaatctgaacgtgagaaattgacccagcagatgatcaagtaccagaaa gaactgaatgaaatgcaggcacaaatagctgaagagagccagattcgaattgaactgcag atgacattggacagtaaagacagtgacattgagcagctgcggtcacaactccaagccttg catattggtctggatagttccagtataggcagtggaccaggggatgctgaggcagatgat gggtttccagaatcaagattagaaggatggctttcattgcctgcacgaaacaacactaag aaatttggatgggttaaaaagtatgtgattgtaagcagtaagaagattcttttctatgac agtgaacaagataaagaacaatctaatccttacatggttttagatatagacaaattattt catgtccgaccagttacacagacagatgtatatagagcagatgctaaagaaattccaagg atattccagattctgtatgccaatgaaggagaaagtaagaaggaacaagaatttccagtg gagccagttggagaaaaatctaattatatttgccacaagggacatgagtttattcctact ctttatcatttcccaaccaactgtgaggcttgtatgaagcccctgtggcacatgtttaag cctcctcctgctttagagtgccgccgttgccatattaagtgtcataaagatcacatggac aaaaaggaggagattatagcaccttgcaaagtgtattatgatatttcaacggcaaagaat ctattattactagcaaattctacagaagagcagcagaagtgggttagtcgattggtgaaa aagataccaaaaaagcccccagctccagacccttttgcacgatcatctcctagaacttca atgaagatacagcaaaaccagtctattagacggccaagtcgacagcttgccccaaacaaa cctagctaa

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