Mandrillus leucophaeus (drill): 105533859
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Entry
105533859 CDS
T08763
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
mleu
Mandrillus leucophaeus (drill)
Pathway
mleu04120
Ubiquitin mediated proteolysis
mleu04144
Endocytosis
mleu04330
Notch signaling pathway
mleu04668
TNF signaling pathway
mleu04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
mleu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
105533859 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
105533859 (ITCH)
04668 TNF signaling pathway
105533859 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
105533859 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
105533859 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mleu04131
]
105533859 (ITCH)
04121 Ubiquitin system [BR:
mleu04121
]
105533859 (ITCH)
Enzymes [BR:
mleu01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
105533859 (ITCH)
Membrane trafficking [BR:
mleu04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
105533859 (ITCH)
Ubiquitin system [BR:
mleu04121
]
Ubiquitin ligases (E3)
HECT type E3
105533859 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
PQQ_2
Motif
Other DBs
NCBI-GeneID:
105533859
NCBI-ProteinID:
XP_011827827
Ensembl:
ENSMLEG00000035500
UniProt:
A0A2K5Z4A3
LinkDB
All DBs
Position
Unknown
AA seq
862 aa
AA seq
DB search
MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIYETLKSNNMKLEEVVVTL
QLGGDREPTETVGDLSICLDGLQLESEVVTNGETICSESASQNDDGSRSKDETRLSTNGS
DDPEDAGAGENRRVSGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNTNTNTSEGATSGLIIPLTISGGSGPRPLNPVTQAPLPPGWEQRVDQHGR
VYYVDHVEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFATSQSKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIAYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSLSPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKIIDTSFSLPFYKRILSKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYVQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPLGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacaacttggttcaatgggtagcctcaccatgaaatcacagctt
cagatcactgtcatctcagcaaaacttaaggaaaataagaagaattggtttggaccaagt
ccttatgtagaggtcacagtagatggacagtcaaagaagacagaaaaatgcaacaacaca
aacagtcctaagtggaagcaaccccttacagttatcgttacccctgtgagtaaattacat
tttcgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctgcatta
gatatttatgaaacattaaagtcaaacaatatgaaacttgaagaagtagttgtgactttg
cagcttggaggtgacagagagccaacagagacagtaggagacttatcaatttgtcttgat
gggctacagttagaatctgaagttgttaccaatggtgaaactatatgttcagaaagtgct
tctcagaatgacgatggctccagatccaaggatgaaacaagactgagcacaaatggatca
gatgatcccgaagatgcaggagctggtgaaaataggagagtcagtgggaataattctcca
tcactctcaaatggcggttttaaaccttctagacctccaagaccttcacgaccaccacca
cccaccccacgtagaccagcatctgtcaatggttcaccatctgccacttctgaaagtgat
gggtctagtacaggctctctgccaccgacaaatacaaatacaaatacatctgaaggagca
acatctggattaataattcctcttactatatctggaggctcaggccctaggccattaaat
cctgtaactcaagctcccttgccacctggttgggagcagagagtggaccagcacggacga
gtttactatgtagatcatgttgagaaaagaacaacatgggatagaccagaacctctacct
cctggctgggaacggcgggttgacaacatgggacgtatttattatgttgaccatttcaca
agaacaacaacgtggcagaggccaacactggaatctgtccggaactatgaacaatggcag
ctacagcgtagtcagcttcaaggagcaatgcagcagtttaaccagagattcatttatggg
aatcaagatttatttgctacatcacaaagtaaagaatttgatcctcttggtccattgcca
cctggatgggagaagagaacagacagcaatggcagagtatatttcgtcaaccacaacact
cgaattacacaatgggaagaccccagaagtcaaggtcaattaaatgaaaagcccttacct
gaaggttgggaaatgagattcacagtggatggaattgcatattttgtggaccacaataga
agaactaccacctatatagatccccgcacaggaaaatctgccctagacaatggacctcag
atagcctatgttcgggacttcaaagcaaaggttcagtatttccgattctggtgtcagcaa
ctggccatgccacagcacataaagattacagtgacaaggaaaacattgtttgaggattcc
tttcaacagataatgagcctcagtccccaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtca
catgaagtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgc
ttgcagataaaccccgcttcttacatcaatccagatcacctgaaatattttcgttttatt
ggcagatttattgccatggctctgttccatgggaaaatcatagacacaagtttttcttta
ccattctataagcgtatcttgagcaaaccagttggactcaaggatttagaatctattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggaatgtggtttg
gaaatgtacttctccgttgacaaagaaattctaggtgaaattaagagtcatgatctgaaa
cctaatggtggcaatattcttgtaacagaagaaaataaagaggaatacatcagaatggta
gctgaatggaggttgtctcgaggtgttgaagaacagacacaagctttctttgagggcttt
aatgaaattcttccccagcaatatgtgcaatactttgatgcaaaggaattagaggtcctt
ttatgtggaatgcaagagattgatttgaatgactggcaaagacatgccatctaccgtcat
tatacgaggaccagcaaacaaatcatgtggttttggcagtttgttaaagaaattgataat
gagaagagaatgagacttctacagtttgttactggaacctgccgattgccactaggagga
tttgctgatctcatggggagcaatggaccacagaaattctgcattgaaaaagttgggaaa
gaaaattggctacccagaagtcatacctgttttaatcgcctggaccttccaccatacaag
agctatgagcaactgaaggaaaagctgttgtttgccatagaagaaacagaaggatttgga
caagagtaa
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integrated database retrieval system
