KEGG   Mandrillus leucophaeus (drill): 105535165
Entry
105535165         CDS       T08763                                 
Symbol
BCL2
Name
(RefSeq) apoptosis regulator Bcl-2 isoform X1
  KO
K02161  apoptosis regulator Bcl-2
Organism
mleu  Mandrillus leucophaeus (drill)
Pathway
mleu01521  EGFR tyrosine kinase inhibitor resistance
mleu01522  Endocrine resistance
mleu01524  Platinum drug resistance
mleu04064  NF-kappa B signaling pathway
mleu04066  HIF-1 signaling pathway
mleu04071  Sphingolipid signaling pathway
mleu04115  p53 signaling pathway
mleu04140  Autophagy - animal
mleu04141  Protein processing in endoplasmic reticulum
mleu04151  PI3K-Akt signaling pathway
mleu04210  Apoptosis
mleu04215  Apoptosis - multiple species
mleu04217  Necroptosis
mleu04261  Adrenergic signaling in cardiomyocytes
mleu04340  Hedgehog signaling pathway
mleu04510  Focal adhesion
mleu04621  NOD-like receptor signaling pathway
mleu04630  JAK-STAT signaling pathway
mleu04722  Neurotrophin signaling pathway
mleu04725  Cholinergic synapse
mleu04915  Estrogen signaling pathway
mleu04928  Parathyroid hormone synthesis, secretion and action
mleu04933  AGE-RAGE signaling pathway in diabetic complications
mleu05014  Amyotrophic lateral sclerosis
mleu05022  Pathways of neurodegeneration - multiple diseases
mleu05132  Salmonella infection
mleu05145  Toxoplasmosis
mleu05152  Tuberculosis
mleu05161  Hepatitis B
mleu05162  Measles
mleu05168  Herpes simplex virus 1 infection
mleu05169  Epstein-Barr virus infection
mleu05170  Human immunodeficiency virus 1 infection
mleu05200  Pathways in cancer
mleu05206  MicroRNAs in cancer
mleu05207  Chemical carcinogenesis - receptor activation
mleu05210  Colorectal cancer
mleu05215  Prostate cancer
mleu05222  Small cell lung cancer
mleu05226  Gastric cancer
mleu05417  Lipid and atherosclerosis
mleu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mleu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    105535165 (BCL2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    105535165 (BCL2)
   04630 JAK-STAT signaling pathway
    105535165 (BCL2)
   04064 NF-kappa B signaling pathway
    105535165 (BCL2)
   04066 HIF-1 signaling pathway
    105535165 (BCL2)
   04071 Sphingolipid signaling pathway
    105535165 (BCL2)
   04151 PI3K-Akt signaling pathway
    105535165 (BCL2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    105535165 (BCL2)
  09143 Cell growth and death
   04210 Apoptosis
    105535165 (BCL2)
   04215 Apoptosis - multiple species
    105535165 (BCL2)
   04217 Necroptosis
    105535165 (BCL2)
   04115 p53 signaling pathway
    105535165 (BCL2)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105535165 (BCL2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    105535165 (BCL2)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    105535165 (BCL2)
   04928 Parathyroid hormone synthesis, secretion and action
    105535165 (BCL2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    105535165 (BCL2)
  09156 Nervous system
   04725 Cholinergic synapse
    105535165 (BCL2)
   04722 Neurotrophin signaling pathway
    105535165 (BCL2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105535165 (BCL2)
   05206 MicroRNAs in cancer
    105535165 (BCL2)
   05207 Chemical carcinogenesis - receptor activation
    105535165 (BCL2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    105535165 (BCL2)
   05226 Gastric cancer
    105535165 (BCL2)
   05215 Prostate cancer
    105535165 (BCL2)
   05222 Small cell lung cancer
    105535165 (BCL2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    105535165 (BCL2)
   05161 Hepatitis B
    105535165 (BCL2)
   05162 Measles
    105535165 (BCL2)
   05168 Herpes simplex virus 1 infection
    105535165 (BCL2)
   05169 Epstein-Barr virus infection
    105535165 (BCL2)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105535165 (BCL2)
   05152 Tuberculosis
    105535165 (BCL2)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    105535165 (BCL2)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    105535165 (BCL2)
   05022 Pathways of neurodegeneration - multiple diseases
    105535165 (BCL2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105535165 (BCL2)
   05418 Fluid shear stress and atherosclerosis
    105535165 (BCL2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    105535165 (BCL2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    105535165 (BCL2)
   01524 Platinum drug resistance
    105535165 (BCL2)
   01522 Endocrine resistance
    105535165 (BCL2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mleu01009]
    105535165 (BCL2)
Protein phosphatases and associated proteins [BR:mleu01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     105535165 (BCL2)
SSDB
Motif
Pfam: Bcl-2 BH4 Bcl-2_3
Other DBs
NCBI-GeneID: 105535165
NCBI-ProteinID: XP_011829561
Ensembl: ENSMLEG00000025336
LinkDB
Position
Unknown
AA seq 247 aa
MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAATPGVAPAPGIFSSQPGHTPHPA
ASRDPVARTSPLPTPAAPAAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH
LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY
LNRHLHTWIQDNGGWVGALGDVSLGWGHRFEVRGLECGWAPGARGGCGAGEIKSGLLLPG
VPTSSSG
NT seq 744 nt   +upstreamnt  +downstreamnt
atggcgcacgctgggagaacagggtacgataaccgggagatagtgatgaagtacatccac
tataagctgtcgcagaggggctacgagtgggatgcgggggatgtgggcgcggcgacccct
ggggtcgcccccgcaccgggcatcttctcctcccagcccgggcacacgccccatcccgcc
gcgtcccgggacccggtcgccaggacctcgccactgccgaccccggctgcccccgccgcc
gccgcggggcctgcgctcagcccggtgccacctgtggtccacctgaccctccgccaggcc
ggtgacgacttctcccgccgctaccgccgcgacttcgccgagatgtccagccagctgcac
ctgacgcccttcaccgcgcggggacgctttgccacggtggtggaggagctcttcagggac
ggggtgaactgggggaggatcgtggccttctttgagttcggtggggtcatgtgtgtggag
agcgtcaaccgggagatgtcgcccctggtggacaacatcgccctgtggatgactgagtac
ctgaaccggcacctgcacacctggatccaggataacggaggctgggtaggtgcacttggt
gatgtgagtctgggctggggccacaggttcgaggtgcgggggttggagtgcgggtgggct
cctggggcaaggggaggctgtggagccggcgaaataaaatcagggttgttgcttcccggc
gtccctacctcttcctctggataa

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