Mandrillus leucophaeus (drill): 105535422 Help Entry 105535422         CDS       T08763                                  Symbol CASP8 Name (RefSeq) caspase-8 isoform X1   KO K04398   caspase 8 [EC:3.4.22.61] Organism mleu  Mandrillus leucophaeus (drill) Pathway mleu01524   Platinum drug resistance mleu04115   p53 signaling pathway mleu04210   Apoptosis mleu04215   Apoptosis - multiple species mleu04217   Necroptosis mleu04620   Toll-like receptor signaling pathway mleu04621   NOD-like receptor signaling pathway mleu04622   RIG-I-like receptor signaling pathway mleu04623   Cytosolic DNA-sensing pathway mleu04625   C-type lectin receptor signaling pathway mleu04657   IL-17 signaling pathway mleu04668   TNF signaling pathway mleu04932   Non-alcoholic fatty liver disease mleu04936   Alcoholic liver disease mleu05010   Alzheimer disease mleu05016   Huntington disease mleu05022   Pathways of neurodegeneration - multiple diseases mleu05132   Salmonella infection mleu05134   Legionellosis mleu05142   Chagas disease mleu05145   Toxoplasmosis mleu05152   Tuberculosis mleu05160   Hepatitis C mleu05161   Hepatitis B mleu05162   Measles mleu05163   Human cytomegalovirus infection mleu05164   Influenza A mleu05165   Human papillomavirus infection mleu05167   Kaposi sarcoma-associated herpesvirus infection mleu05168   Herpes simplex virus 1 infection mleu05169   Epstein-Barr virus infection mleu05170   Human immunodeficiency virus 1 infection mleu05200   Pathways in cancer mleu05203   Viral carcinogenesis mleu05416   Viral myocarditis mleu05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mleu00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     105535422 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     105535422 (CASP8)    04215 Apoptosis - multiple species     105535422 (CASP8)    04217 Necroptosis     105535422 (CASP8)    04115 p53 signaling pathway     105535422 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     105535422 (CASP8)    04621 NOD-like receptor signaling pathway     105535422 (CASP8)    04622 RIG-I-like receptor signaling pathway     105535422 (CASP8)    04623 Cytosolic DNA-sensing pathway     105535422 (CASP8)    04625 C-type lectin receptor signaling pathway     105535422 (CASP8)    04657 IL-17 signaling pathway     105535422 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105535422 (CASP8)    05203 Viral carcinogenesis     105535422 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     105535422 (CASP8)    05161 Hepatitis B     105535422 (CASP8)    05160 Hepatitis C     105535422 (CASP8)    05164 Influenza A     105535422 (CASP8)    05162 Measles     105535422 (CASP8)    05168 Herpes simplex virus 1 infection     105535422 (CASP8)    05163 Human cytomegalovirus infection     105535422 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     105535422 (CASP8)    05169 Epstein-Barr virus infection     105535422 (CASP8)    05165 Human papillomavirus infection     105535422 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     105535422 (CASP8)    05134 Legionellosis     105535422 (CASP8)    05152 Tuberculosis     105535422 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     105535422 (CASP8)    05142 Chagas disease     105535422 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     105535422 (CASP8)    05016 Huntington disease     105535422 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     105535422 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     105535422 (CASP8)    05416 Viral myocarditis     105535422 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     105535422 (CASP8)    04932 Non-alcoholic fatty liver disease     105535422 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     105535422 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:mleu01002]     105535422 (CASP8) Enzymes [BR:mleu01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      105535422 (CASP8) Peptidases and inhibitors [BR:mleu01002]  Cysteine peptidases   Family C14: caspase family    105535422 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  105535422 NCBI-ProteinID:  XP_011829891 Ensembl:  ENSMLEG00000032037 LinkDB All DBs Position Unknown AA seq 496 aa AA seqDB search MVPGKGGADYILLPFEEMDFNRNLYDIGEQLDSEELASLKFLSLDCIPQRKQEPIKDALM LFQRLQEKRMLEENNLSFLKELLFRINRLDLLTTYLNTRKEEMERELQAPGRAQISAYRV MLYQISEEVGRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRV CAQVNKSLLKIINDYEEFSRERTRSLEGRPEEGSNGEELCGLMTISDSPREQDSESQTLD KVYQMKSKPRGYCLIINNYDFTKAREKVPKLHSIRDRNGTHLDAEALTATFEELHFEIQH HNDCTVEKIYKILKTYQLMDHSNKDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGL KCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGM ATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQM PQPTFTLRKKLVFPSD NT seq 1491 nt NT seq  +upstreamnt  +downstreamnt atggtgccaggaaagggtggagcggattatattctgctgccttttgaagagatggacttc aacagaaatctttatgatattggggaacaactggacagtgaagagctggcctccctcaag ttcctgagcctggactgcattccacaaaggaagcaagaacccatcaaggatgccttgatg ttattccagagactccaggaaaagagaatgttggaggaaaacaatctgtccttcctgaag gagctgctcttccgaattaatagactggatttgctcactacttacctaaacactagaaag gaggagatggaaagggaacttcaggcaccaggcagggctcagatttctgcctacagggtc atgctctatcagatttcagaagaggtgggcagatcagaattgaggtcttttaagtttctt ctgcaagaggagatctccaaatgcaaactggatgatgacatgaacctgctggatattttc atagagatggagaagagggtcatcctgggagaaggcaagttggacatcctgaagagagtc tgtgcccaagtcaacaagagcctgctgaagataatcaatgactatgaagaattcagcaga gagagaacaaggagccttgaaggacgtcctgaggaaggttcaaatggggaggagttgtgt gggctaatgacaatctcggactctccaagagaacaggatagtgaatcacagactttggac aaagtttaccaaatgaaaagcaaacctcggggatactgtctgatcatcaacaattacgat tttaccaaagcacgggagaaagtgcccaaacttcacagcattagggacaggaatggaaca cacttggatgcagaggctttgactgcgacctttgaagagcttcattttgagatccagcac cacaatgactgcacagtagagaaaatctataagattttgaaaacctaccaactcatggac cacagtaacaaggattgcttcatctgctgtatcctctcccatggagacaagggcatcatc tatggcactgatggacaggaggcccccatctatgagctgacatctcagttcactggtttg aagtgcccttcccttgctggaaaacccaaagtgttttttattcaggcttgtcagggggat aactaccagaaaggtatacctgttgagactgattcagaggagcaaccctatttggaaatg gatttatcatcacctcaaacgagatatatcccggatgaggctgactttctgctggggatg gccactgtgaataactgtgtttcctaccgaaaccctgcagagggaacctggtacatccag tcactttgccagagcctgagagaacgatgtcctcgaggcgatgatattctcaccatcctg actgaagtgaactatgaagtaagcaacaaggatgacaagaaaaacatgggaaaacagatg ccacagccaactttcacactaagaaaaaaacttgtcttcccttctgattga

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