KEGG   Mandrillus leucophaeus (drill): 105545589
Entry
105545589         CDS       T08763                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4 isoform X1
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
mleu  Mandrillus leucophaeus (drill)
Pathway
mleu01522  Endocrine resistance
mleu04110  Cell cycle
mleu04115  p53 signaling pathway
mleu04151  PI3K-Akt signaling pathway
mleu04218  Cellular senescence
mleu04530  Tight junction
mleu04660  T cell receptor signaling pathway
mleu04933  AGE-RAGE signaling pathway in diabetic complications
mleu04934  Cushing syndrome
mleu05160  Hepatitis C
mleu05162  Measles
mleu05163  Human cytomegalovirus infection
mleu05164  Influenza A
mleu05165  Human papillomavirus infection
mleu05166  Human T-cell leukemia virus 1 infection
mleu05167  Kaposi sarcoma-associated herpesvirus infection
mleu05169  Epstein-Barr virus infection
mleu05200  Pathways in cancer
mleu05203  Viral carcinogenesis
mleu05212  Pancreatic cancer
mleu05214  Glioma
mleu05218  Melanoma
mleu05219  Bladder cancer
mleu05220  Chronic myeloid leukemia
mleu05222  Small cell lung cancer
mleu05223  Non-small cell lung cancer
mleu05224  Breast cancer
mleu05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:mleu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    105545589 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    105545589 (CDK4)
   04115 p53 signaling pathway
    105545589 (CDK4)
   04218 Cellular senescence
    105545589 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    105545589 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    105545589 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105545589 (CDK4)
   05203 Viral carcinogenesis
    105545589 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    105545589 (CDK4)
   05225 Hepatocellular carcinoma
    105545589 (CDK4)
   05214 Glioma
    105545589 (CDK4)
   05220 Chronic myeloid leukemia
    105545589 (CDK4)
   05218 Melanoma
    105545589 (CDK4)
   05219 Bladder cancer
    105545589 (CDK4)
   05224 Breast cancer
    105545589 (CDK4)
   05222 Small cell lung cancer
    105545589 (CDK4)
   05223 Non-small cell lung cancer
    105545589 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105545589 (CDK4)
   05160 Hepatitis C
    105545589 (CDK4)
   05164 Influenza A
    105545589 (CDK4)
   05162 Measles
    105545589 (CDK4)
   05163 Human cytomegalovirus infection
    105545589 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105545589 (CDK4)
   05169 Epstein-Barr virus infection
    105545589 (CDK4)
   05165 Human papillomavirus infection
    105545589 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    105545589 (CDK4)
   04934 Cushing syndrome
    105545589 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    105545589 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mleu01001]
    105545589 (CDK4)
Enzymes [BR:mleu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     105545589 (CDK4)
Protein kinases [BR:mleu01001]
 Serine/threonine kinases: CMGC group
  CDK family
   105545589 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 105545589
NCBI-ProteinID: XP_011843994
Ensembl: ENSMLEG00000037320
UniProt: A0A2K5ZEQ5
LinkDB
Position
Unknown
AA seq 303 aa
MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEG
NPE
NT seq 912 nt   +upstreamnt  +downstreamnt
atggctacctctcgatatgagccagtggctgaaattggtgtcggtgcctatgggacagtg
tacaaggcccgtgatccccacagtggccactttgtggccctcaagagtgtgagagtcccc
aatggaggaggagctggaggaggccttcccatcagcacagttcgggaggtggccttactg
aggcgactggaggcttttgaacatcccaatgtagtccggctgatggacgtctgtgccaca
tcccgaactgaccgggagatcaaggtaaccctggtgtttgagcatgtagaccaagaccta
aggacgtatctggacaaagcacccccaccaggcttgccagccgagaccatcaaggatttg
atgcgccagtttctaagaggcctagattttcttcatgcaaattgcatcgttcaccgagat
ctgaagccagagaacattctggtgacaagtggtggaacagtcaagctggctgactttggc
ctggccagaatctacagctaccagatggcacttacacccgtggttgttacactctggtac
cgagctcccgaagttcttctgcagtccacatatgcaacacctgtggacatgtggagtgtt
ggctgtatctttgcagagatgtttcgtcgaaagcctctcttctgtggaaactctgaagct
gaccagttgggcaaaatctttgacctgattgggctgcctccagaggatgactggcctcga
gatgtatccctgccccgtggagcctttccccccagagggccccgcccagtgcagtcggtg
gtacctgagatggaggaatcgggagcacagctgctgctggaaatgctgacttttaaccca
cacaagcgaatctctgcctttcgagctctgcagcactcttatctacataaggatgaaggt
aatccggagtga

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