Mandrillus leucophaeus (drill): 105546847 Help Entry 105546847         CDS       T08763                                  Symbol PTK2 Name (RefSeq) focal adhesion kinase 1   KO K05725   focal adhesion kinase 1 [EC:2.7.10.2] Organism mleu  Mandrillus leucophaeus (drill) Pathway mleu01522   Endocrine resistance mleu04012   ErbB signaling pathway mleu04062   Chemokine signaling pathway mleu04148   Efferocytosis mleu04151   PI3K-Akt signaling pathway mleu04360   Axon guidance mleu04370   VEGF signaling pathway mleu04510   Focal adhesion mleu04517   IgSF CAM signaling mleu04518   Integrin signaling mleu04670   Leukocyte transendothelial migration mleu04810   Regulation of actin cytoskeleton mleu04935   Growth hormone synthesis, secretion and action mleu05100   Bacterial invasion of epithelial cells mleu05135   Yersinia infection mleu05146   Amoebiasis mleu05163   Human cytomegalovirus infection mleu05165   Human papillomavirus infection mleu05170   Human immunodeficiency virus 1 infection mleu05200   Pathways in cancer mleu05202   Transcriptional misregulation in cancer mleu05205   Proteoglycans in cancer mleu05208   Chemical carcinogenesis - reactive oxygen species mleu05222   Small cell lung cancer mleu05417   Lipid and atherosclerosis mleu05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:mleu00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     105546847 (PTK2)    04370 VEGF signaling pathway     105546847 (PTK2)    04151 PI3K-Akt signaling pathway     105546847 (PTK2)   09133 Signaling molecules and interaction    04517 IgSF CAM signaling     105546847 (PTK2)    04518 Integrin signaling     105546847 (PTK2)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     105546847 (PTK2)   09144 Cellular community - eukaryotes    04510 Focal adhesion     105546847 (PTK2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     105546847 (PTK2)  09150 Organismal Systems   09151 Immune system    04670 Leukocyte transendothelial migration     105546847 (PTK2)    04062 Chemokine signaling pathway     105546847 (PTK2)   09152 Endocrine system    04935 Growth hormone synthesis, secretion and action     105546847 (PTK2)   09158 Development and regeneration    04360 Axon guidance     105546847 (PTK2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105546847 (PTK2)    05202 Transcriptional misregulation in cancer     105546847 (PTK2)    05205 Proteoglycans in cancer     105546847 (PTK2)    05208 Chemical carcinogenesis - reactive oxygen species     105546847 (PTK2)   09162 Cancer: specific types    05222 Small cell lung cancer     105546847 (PTK2)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     105546847 (PTK2)    05163 Human cytomegalovirus infection     105546847 (PTK2)    05165 Human papillomavirus infection     105546847 (PTK2)   09171 Infectious disease: bacterial    05135 Yersinia infection     105546847 (PTK2)    05100 Bacterial invasion of epithelial cells     105546847 (PTK2)   09174 Infectious disease: parasitic    05146 Amoebiasis     105546847 (PTK2)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     105546847 (PTK2)    05418 Fluid shear stress and atherosclerosis     105546847 (PTK2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     105546847 (PTK2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mleu01001]     105546847 (PTK2)    01009 Protein phosphatases and associated proteins [BR:mleu01009]     105546847 (PTK2) Enzymes [BR:mleu01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      105546847 (PTK2) Protein kinases [BR:mleu01001]  Non-receptor tyrosine kinases   FAK family    105546847 (PTK2) Protein phosphatases and associated proteins [BR:mleu01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      105546847 (PTK2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Focal_AT Pkinase FERM_N_2 FERM_C_FAK1 FERM_M Kinase-like Haspin_kinase FERM_F2 ABC1 Motif Other DBs NCBI-GeneID:  105546847 NCBI-ProteinID:  XP_011845540 Ensembl:  ENSMLEG00000030892 LinkDB All DBs Position Unknown AA seq 1140 aa AA seqDB search MLLELAGQEALKPAGAIYMEKSGCSPFPVCWAKEYDRYLASSKIMAAAYLDPNLNHTPNS STKTHLGTGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHK VKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQ FTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEV LEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE CFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQTIQYSNSEDKDRKGML QLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGASQSFIIRPQKEGERALPSIPKL ANSEKQGMRTHAVSVSGVSHCQHKVKKARRFLPLVFCSHDPPSTDEISGDETDDYAEIID EEDTYTMPSKSYGIDEARDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKT CKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRK YSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDST YYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMES RRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITA MAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTALDLRGIGQVLPTHLMEERLIRQ QQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKK PPRPGAPGHLGSLASLSSPADSYNEGVKPWRLQPQEISPPPTANLDRSNDKVYENVTGLV KAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQKLLNS DLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH NT seq 3423 nt NT seq  +upstreamnt  +downstreamnt atgttgttggaactggcaggccaagaggccctgaaaccagcaggtgccatctatatggag aaaagcggctgtagtccgtttccagtgtgttgggctaaagaatatgacagatacctagca tctagcaaaataatggcagctgcttaccttgaccccaacttgaatcacacaccaaattcg agtactaagactcacctgggtactggtatggaacgttctcctggtgcgatggagcgagta ttaaaggtctttcattattttgaaagcaatagtgagccaaccacctgggccagtattatc aggcatggagatgctactgatgtcaggggcatcattcagaagatagtggacagtcacaaa gtaaagcatgtggcctgctatggattccgcctcagtcacctgcggtcagaggaggttcac tggcttcacgtggatatgggcgtctccagtgtgagggagaagtatgagcttgcccaccca ccagaggagtggaaatatgaattgagaattcgttatttgccaaaaggatttctaaaccag tttactgaagataagccaactttgaatttcttctatcaacaggtgaagagcgattatatg ttagagatagctgatcaagtggaccaggaaattgctttgaagttgggttgtctagaaata cggcgatcatactgggagatgcggggcaatgccctagaaaagaagtctaactatgaagta ttagaaaaagatgttggtttaaagcgattttttcctaagagtttactggattctgtcaag gccaaaacactaagaaaactgatccaacaaacatttagacaattcgccaaccttaataga gaagaaagtattctgaaattctttgagatcctgtctccagtctacagatttgataaggaa tgcttcaagtgtgctcttggttcaagctggattatttcagtggaattggcaatcggccca gaagaagggatcagttacctaacagacaagggctgcaatcccacacatcttgctgacttc actcaagtgcagaccattcagtattcaaacagtgaagataaggacagaaaaggaatgcta caactaaaaatagcaggtgcacccgagcctctgacagtgacggcaccatccctaaccatt gcggagaatatggctgacctgatagatgggtattgccggctggtgaatggagcctcgcag tcatttatcatcagaccccagaaagaaggtgaacgggctttgccatcaataccaaagttg gccaacagcgaaaagcaaggcatgcggacacacgccgtctctgtgtcaggagtcagtcac tgccaacataaagttaagaaagctaggcgctttctccctttggtcttctgttcccatgat cctccttctacggatgaaattagtggggacgaaacagatgattatgctgagattatagat gaagaagatacttacaccatgccctcaaaaagctatggaatagatgaagccagggattat gagattcaaagagaaagaatagaacttggacgatgtattggagaaggccaatttggagat gtacatcaaggcatttatatgagtccagagaatccagctttggcggttgcaattaaaaca tgtaaaaactgtacttcggacagcgtgagagagaaatttcttcaagaagccttaacaatg cgtcagtttgaccatcctcatattgtgaagctgattggagtcatcacagagaatcctgtc tggataatcatggagctctgcacacttggagagctgaggtcgtttttgcaagtaaggaaa tacagtttggatctagcatctttgatcctgtatgcctatcagcttagtacagctcttgca tatctagagagcaaaagatttgtacacagggacattgctgctcggaatgttctggtgtcc tcaaatgattgtgtaaaattaggagactttggattatcccgatatatggaagatagtact tactacaaagcttccaaaggaaaattgcctattaaatggatggctccagagtcaatcaat tttcgacgttttacctcagctagtgacgtatggatgtttggtgtgtgtatgtgggagata ctgatgcatggtgtgaagccttttcaaggagtgaagaacaatgatgtaatcggtcgaatt gaaaatggggaaagattaccaatgcctccaaattgtcctcctaccctctacagccttatg acgaaatgctgggcctatgaccccagcaggcggcccaggtttactgaacttaaagctcag ctcagcacaatcctggaggaagagaaggctcagcaagaagaacgcatgaggatggagtcc agaagacaggccacagtgtcctgggactccggagggtctgatgaagcgccacccaagccc agcagaccgggttatcctagtccgaggtccagcgaaggattttatcccagcccacagcac atggtacaaaccaatcattaccaggtttctggctaccctggttcacatggaatcacagcc atggctggcagcatctatccaggtcaggcatctcttttggaccaaacagattcatggaat catagacctcaggagatagcaatgtggcagcccaatgtggaggactctacagcattggac ctgcgagggattgggcaagtgttgccaacccacctgatggaagagcggctaatccgacag caacaggaaatggaagaagatcagcgctggctggaaaaagaggaaagatttctgaaacct gatgtgagactctctcgaggcagtattgacagggaggatggaagtcttcagggtccgatt ggaaaccaacatatatatcagcctgtgggtaaaccagatcctgcagctccaccaaagaaa ccgcctcgccctggagctcccggtcacctgggaagccttgccagcctcagcagccctgct gacagctacaacgagggtgtcaagccatggaggcttcagccccaggaaatcagccctcct cctactgccaacctggaccggtcaaatgataaggtgtacgagaatgtgacgggcctggtg aaagctgtcatcgagatgtccagtaaaatccagccagccccaccagaggagtatgtccct atggtgaaggaagtcggcttggccctgaggacgttattggccactgtggatgagaccatt cccctcctaccagccagcacccaccgagagattgagatggcacagaaactattgaactct gacctgggtgagctcatcaacaagatgaaactggcccagcagtatgtcatgaccagtctc cagcaagagtacaaaaagcaaatgctgactgctgctcacgccctggctgtggatgccaaa aacttactcgatgtcattgaccaagcaagactgaaaatgcttgggcagacgagaccacac tga

DBGET integrated database retrieval system