Mandrillus leucophaeus (drill): 105547548 Help Entry 105547548         CDS       T08763                                  Symbol JAK3 Name (RefSeq) tyrosine-protein kinase JAK3   KO K11218   Janus kinase 3 [EC:2.7.10.2] Organism mleu  Mandrillus leucophaeus (drill) Pathway mleu04062   Chemokine signaling pathway mleu04151   PI3K-Akt signaling pathway mleu04217   Necroptosis mleu04550   Signaling pathways regulating pluripotency of stem cells mleu04630   JAK-STAT signaling pathway mleu04658   Th1 and Th2 cell differentiation mleu04659   Th17 cell differentiation mleu05161   Hepatitis B mleu05162   Measles mleu05166   Human T-cell leukemia virus 1 infection mleu05169   Epstein-Barr virus infection mleu05200   Pathways in cancer mleu05203   Viral carcinogenesis mleu05223   Non-small cell lung cancer mleu05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:mleu00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     105547548 (JAK3)    04151 PI3K-Akt signaling pathway     105547548 (JAK3)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     105547548 (JAK3)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     105547548 (JAK3)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     105547548 (JAK3)    04659 Th17 cell differentiation     105547548 (JAK3)    04062 Chemokine signaling pathway     105547548 (JAK3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105547548 (JAK3)    05203 Viral carcinogenesis     105547548 (JAK3)   09162 Cancer: specific types    05223 Non-small cell lung cancer     105547548 (JAK3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     105547548 (JAK3)    05161 Hepatitis B     105547548 (JAK3)    05162 Measles     105547548 (JAK3)    05169 Epstein-Barr virus infection     105547548 (JAK3)   09163 Immune disease    05340 Primary immunodeficiency     105547548 (JAK3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mleu01001]     105547548 (JAK3) Enzymes [BR:mleu01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      105547548 (JAK3) Protein kinases [BR:mleu01001]  Non-receptor tyrosine kinases   JAK family [OT]    105547548 (JAK3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 FERM_F1 SH2_1 Kinase-like ABC1 Kdo SH2 LRR_RI_capping Haspin_kinase Motif Other DBs NCBI-GeneID:  105547548 NCBI-ProteinID:  XP_011846595 Ensembl:  ENSMLEG00000034517 LinkDB All DBs Position Unknown AA seq 1086 aa AA seqDB search MTVAQETKGPTQEGAEWDFPLAASRLCSPFEGPGSLPARQVALMAPPSEETPLIPQRSCS LLSTEAGALHVLLPARGPGPPQRLSFSFGDHLAEDLCVQAAKASGILPVYHSLFALATED LSYWFPPSHIFSVEDASTQVLLYRIRFYFPNWFGLDKCHRFGLRKDLASAILDLPVLEHL FAQHRSDLVSGRLAVGLSLKEQGECLSLAVLDLARMAREQAQRPGELLKTVSYKACLPPS LRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMAKYIMDLERLDPAGAAETFHVS LPGVPGGQDGLGLLRVAGDGGIAWTQGEQEVRADPPLGGTNVGLDFAINKLKNGGSRPGS YVLRRSPQDFDSFLLTVCVQTPLGPDYKGCLIRRSPTGSFFLVGLSRSHSSLRELLAACW DGGLHVDGVTVTLTSCCIPRPKEKSNLIVVQRGRSPPTSSLVQPQSQCQLSQMIFHKIPA DSLEWHENLGHGSFTKIYRGCRHEAVDGESRKTEVLLKVMDAKHKNCMESFLEAASLMSQ VSYRHLVLLHGVCMAGDSTMVQEFVHLGAIDTYLRKRGHLVPASWKLQVVKQLAYALNYL EDKGLPHGNVSARKVLLAREGTDGSPPFIKLSDPGVSPAVLSLEMLTDRIPWVAPECLWK AQTLSLEADKWGFGATVWEVFSGVTMPISALDPAKKLQFYEDRQQLPAPKWTELALLIQQ CMAYEPVQRPSFRAVIRDLNSLISSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFE ERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKAL HSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGME YLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPES LSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMGCERDVPALCRLLELLEEGQ RLPAPPACPAEVHELMKLCWAPSPQDRPSFSTLGPQLDMLWSGSRGCETHAFTAHPEGKP HSLSFL NT seq 3261 nt NT seq  +upstreamnt  +downstreamnt atgacagtggctcaggaaaccaaggggcccacacaggaaggagccgagtgggactttcct ctcgctgcctcccggctctgctctcccttcgaaggtccagggtccctgcctgctaggcaa gttgcactcatggcacctccgagtgaggagacacccctgatccctcagcgctcctgcagc ctcttgtccacggaggctggtgccctgcacgtgctactgcccgctcggggccccgggccc ccccagcgcctatctttctcctttggggaccacttggctgaggacctgtgcgtgcaggct gccaaggccagcggcatcctgcctgtgtaccactccctctttgctctggccacggaggac ctgtcctactggttccccccaagccacatcttctccgtggaggatgccagcacccaagtc ctgctctacaggattcgtttttacttccccaattggtttgggctggacaagtgccaccgc ttcgggctacgcaaggatttggccagcgctatccttgacctgccagtcctggagcacctc tttgcccagcaccgcagtgacctggtgagtgggcgcctcgctgtgggcctcagcctcaag gagcagggtgagtgtctcagcctggccgtgctggacctggcccggatggcgcgagagcag gcccagcggccaggagagctgctgaagactgtcagctacaaggcctgcctgcccccaagc ctgcgcgacctgatccagggcctgagcttcgtgacgcggaggcgtattcggaggacagta cgcagggccctgcgccgcgtggccgcctgccaggccgaccggcactcgctcatggccaag tacattatggatctggagcggctggatccggctggggccgccgagaccttccacgtgagc ctccctggggtccctggtggccaggacgggctggggctgctccgcgtggctggtgacgga ggcatcgcctggacccagggagaacaggaggtgagggcggaccctccgctgggcgggacc aacgtgggtctggactttgccataaacaagcttaagaatgggggctcacgtcctggctcc tatgttctccgccgcagcccccaggactttgacagcttcctcctcactgtctgtgtacag accccccttggtcctgattataaaggttgcctcattcggcgcagccccacagggagcttc tttctggttggcctcagccgatcccacagcagtcttcgagagctcctggcagcctgctgg gatggggggctgcacgtagatggggtcacagtgaccctcacctcctgctgtatccccaga cccaaagaaaagtccaacttgatcgtggtccagagaggtcgcagcccacccacgtcctcc ctggttcagccccaatcccaatgccagctgagtcagatgatatttcacaagatccccgct gacagcctagagtggcatgagaacctgggccatgggtccttcaccaagatttaccggggc tgtcgtcacgaggcggtggatggggagtcccgaaagacagaggtgctgctaaaagtgatg gatgctaagcacaagaactgcatggagtcattcctggaagcagcgagcttgatgagccaa gtgtcgtaccggcatctcgtgctgctccacggcgtgtgcatggctggagacagcaccatg gtgcaagaatttgtacacctgggggcgatagacacgtatctgcgaaaacgtggccacctg gtaccagccagctggaagctgcaggtggtcaaacagctggcctacgccctcaactatctg gaggacaaaggcctcccccatggcaatgtctctgcccggaaggtgctcctggctcgggag ggcactgatgggagcccgcccttcatcaagctaagtgaccctggggtcagccccgctgtg ttaagcctggagatgctcaccgacaggatcccctgggtggctcccgagtgtctttggaag gcccagacacttagcttggaagctgacaagtggggcttcggcgccacggtctgggaggtg tttagtggcgtcaccatgcccatcagcgccctggatcctgctaagaaactccaattttat gaggaccggcagcagctgccagcccccaagtggacagagctggccctgctaattcagcag tgcatggcctatgagccagtccagaggccctccttccgagccgtcattcgtgacctcaac agcctcatctcttcagactatgagctcctctcagaccccacacctggtgccctggcacct cgtgatgggctgtggaatggtgcccagctctatgcctgccaagaccccacgatcttcgag gagagacacctcaagtacatctcacagctgggcaagggcaactttggcagcgtggagctg tgccgctatgacccgctaggcgacaacacaggtgccctggtggccgtgaaacagctgcag cacagcgggccagaccagcagagggacttccagcgggagattcagatcctcaaagcactg cacagtgatttcattgtcaagtatcgtggtgtcagctacggcccgggccgccagagcctg cggctggtcatggagtacctgcccagcggctgcttgcgcgacttcctgcagcggcaccgc gcgcgcctcgatgccagccgcctcctgctctactcctcgcagatctgcaagggcatggag tacctgggttcccgccgctgcgtgcaccgcgacctggccgcccgaaacatcctggtggag agcgaggcacacgtcaagatcgctgacttcggcctagctaagctgctgccgcttgacaaa gactactacgtggtccgcgagccgggccagagccccattttctggtatgcccccgaatcc ctctcggacaacatcttctctcgccagtcagacgtctggagcttcggggtcgtcctgtac gagctcttcacctactgcgacaaaagctgcagcccctcggccgagtttctgcggatgatg ggatgtgagcgggatgtccccgccctctgccgcctcctggagctgctggaggagggtcag aggctgccggcgcctcctgcctgccctgctgaggttcacgagctcatgaagctgtgctgg gcccctagcccacaggaccggccatcattcagcaccctgggcccccagctggacatgcta tggagcggaagccgggggtgtgagactcacgccttcactgctcacccagagggcaaacca cactccctgtcctttttatag

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