Mandrillus leucophaeus (drill): 105552315
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Entry
105552315 CDS
T08763
Symbol
PTPN11
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 11
KO
K07293
tyrosine-protein phosphatase non-receptor type 11 [EC:
3.1.3.48
]
Organism
mleu
Mandrillus leucophaeus (drill)
Pathway
mleu04014
Ras signaling pathway
mleu04072
Phospholipase D signaling pathway
mleu04148
Efferocytosis
mleu04360
Axon guidance
mleu04625
C-type lectin receptor signaling pathway
mleu04630
JAK-STAT signaling pathway
mleu04650
Natural killer cell mediated cytotoxicity
mleu04660
T cell receptor signaling pathway
mleu04670
Leukocyte transendothelial migration
mleu04722
Neurotrophin signaling pathway
mleu04920
Adipocytokine signaling pathway
mleu04931
Insulin resistance
mleu05168
Herpes simplex virus 1 infection
mleu05205
Proteoglycans in cancer
mleu05208
Chemical carcinogenesis - reactive oxygen species
mleu05211
Renal cell carcinoma
mleu05220
Chronic myeloid leukemia
mleu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
mleu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
105552315 (PTPN11)
04630 JAK-STAT signaling pathway
105552315 (PTPN11)
04072 Phospholipase D signaling pathway
105552315 (PTPN11)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
105552315 (PTPN11)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
105552315 (PTPN11)
04650 Natural killer cell mediated cytotoxicity
105552315 (PTPN11)
04660 T cell receptor signaling pathway
105552315 (PTPN11)
04670 Leukocyte transendothelial migration
105552315 (PTPN11)
09152 Endocrine system
04920 Adipocytokine signaling pathway
105552315 (PTPN11)
09156 Nervous system
04722 Neurotrophin signaling pathway
105552315 (PTPN11)
09158 Development and regeneration
04360 Axon guidance
105552315 (PTPN11)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
105552315 (PTPN11)
05208 Chemical carcinogenesis - reactive oxygen species
105552315 (PTPN11)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
105552315 (PTPN11)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
105552315 (PTPN11)
05211 Renal cell carcinoma
105552315 (PTPN11)
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
105552315 (PTPN11)
09167 Endocrine and metabolic disease
04931 Insulin resistance
105552315 (PTPN11)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
mleu01009
]
105552315 (PTPN11)
Enzymes [BR:
mleu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
105552315 (PTPN11)
Protein phosphatases and associated proteins [BR:
mleu01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
105552315 (PTPN11)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Y_phosphatase
SH2
SH2_1
PTP-SAK
Tc-R-P
DSPc
PTPlike_phytase
Y_phosphatase3
PTP-NADK
Motif
Other DBs
NCBI-GeneID:
105552315
NCBI-ProteinID:
XP_011853329
Ensembl:
ENSMLEG00000026873
UniProt:
A0A2K5XTC2
LinkDB
All DBs
Position
Unknown
AA seq
656 aa
AA seq
DB search
MNEIDVAVGPDAPGRWSGVAAERAAHTRQPRFPGGSKDALDAALSASAEPPRCHSRPWLG
PRLTGSRKWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQ
NTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHL
SGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQEL
KYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLA
ETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDP
NEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTT
KEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQ
YHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILID
IIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKR
KGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR
NT seq
1971 nt
NT seq
+upstream
nt +downstream
nt
atgaatgaaatcgatgtggcagtgggcccggacgcgccaggtcggtggagtggcgtagcc
gccgagcgcgcagctcacacccggcagccgcgatttccgggaggaagcaaggatgctttg
gacgctgcgcttagcgcctccgcggaacccccgcgctgccattcccggccgtggctcggt
cctcggctgacgggaagcaggaaatggtttcacccaaatatcactggtgtggaggcggaa
aacctactgttgacaagaggagttgatggcagttttttggcaaggcctagtaaaagtaac
cctggagacttcacactttccgttcgaagaaatggagctgtcacccacatcaagattcag
aacactggtgattactatgacctgtatggaggggagaaatttgccactttggcagagttg
gtccagtattacatggaacatcacgggcaattaaaagagaagaatggagatgttattgag
cttaaatatcctctgaactgtgcagatcctacctctgaaaggtggtttcatggacacctc
tctgggaaagaagcagagaaattattaactgaaaaaggaaaacatggtagttttcttgta
cgagagagccagagccaccctggagattttgttctctctgtgcgcactggtgatgacaaa
ggggagagcaatgacggcaagtctaaagtgacccatgttatgattcgctgtcaggaactg
aaatatgacgttggcggaggagaacggtttgattctttgacagatcttgtggaacattac
aagaaaaatcctatggtggaaacattgggtacagtactacaactcaagcagccccttaac
acgactcgtataaatgctgctgaaatagaaagcagagttcgagaactaagcaaattagct
gagaccacagataaagtcaaacaaggcttttgggaagaatttgagacactacaacaacag
gagtgcaaacttctgtacagccgaaaagagggtcaaaggcaagaaaacaaaaacaaaaat
agatataaaaacatcctgccctttgatcataccagggttgtcctacatgatggtgatccc
aatgagcctgtttcagattacatcaatgcaaatatcatcatgcctgaatttgaaaccaag
tgcaacaattcaaagcccaaaaagagttacattgccacacaaggctgcctgcagaacaca
gtgaacgacttttggcggatggtgttccaagaaaactcccgagtgattgtcatgacaacg
aaagaagtggagagaggaaagagtaaatgtgtcaaatactggcctgatgagtatgcttta
aaagaatatggcgtcatgcgtgttaggaacgtcaaagaaagtgccgctcatgactatacg
ctaagagaacttaaactttcaaaggttggacaagggaatacggagagaacggtctggcaa
taccactttcggacctggccggaccacggagtgcccagcgaccccgggggcgtgctggac
ttcctggaggaggtgcaccataagcaggagagcatcatggatgcagggccggtcgtggtg
cactgcagtgctggaattggccggacagggacattcattgtgattgatattcttattgac
atcatcagagagaaaggtgttgactgcgacattgacgttcccaaaaccatccagatggtg
cggtctcagaggtcagggatggtccagacagaagcacagtaccgatttatctatatggcg
gtccagcattatattgaaacactacagcgcaggattgaagaagagcagaaaagcaagagg
aaagggcatgaatatacaaatattaagtattctctagcggaccagacgagtggagatcag
agccccctcccgccttgtactccaacgccaccctgtgcagaaatgagagaagacagtgct
agagtctatgaaaacgtgggcctgatgcaacagcagaaaagtttcagatga
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