Mandrillus leucophaeus (drill): 105552471
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Entry
105552471 CDS
T08763
Symbol
FASN
Name
(RefSeq) fatty acid synthase
KO
K00665
fatty acid synthase, animal type [EC:
2.3.1.85
]
Organism
mleu
Mandrillus leucophaeus (drill)
Pathway
mleu00061
Fatty acid biosynthesis
mleu01100
Metabolic pathways
mleu01212
Fatty acid metabolism
mleu04152
AMPK signaling pathway
mleu04910
Insulin signaling pathway
mleu04936
Alcoholic liver disease
Module
mleu_M00082
Fatty acid biosynthesis, initiation
mleu_M00083
Fatty acid biosynthesis, elongation
Brite
KEGG Orthology (KO) [BR:
mleu00001
]
09100 Metabolism
09103 Lipid metabolism
00061 Fatty acid biosynthesis
105552471 (FASN)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
105552471 (FASN)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
105552471 (FASN)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
105552471 (FASN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
mleu01004
]
105552471 (FASN)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mleu04147
]
105552471 (FASN)
Enzymes [BR:
mleu01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.85 fatty-acid synthase system
105552471 (FASN)
Lipid biosynthesis proteins [BR:
mleu01004
]
Fatty acid synthase
Animal type
105552471 (FASN)
Exosome [BR:
mleu04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
105552471 (FASN)
Exosomal proteins of breast milk
105552471 (FASN)
Exosomal proteins of colorectal cancer cells
105552471 (FASN)
Exosomal proteins of bladder cancer cells
105552471 (FASN)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Acyl_transf_1
ketoacyl-synt
Thioesterase
KR
Ketoacyl-synt_C
KAsynt_C_assoc
FAS_pseudo-KR
ADH_zinc_N
ADH_zinc_N_2
PKS_DH_N
PP-binding
Methyltransf_12
adh_short
Methyltransf_31
Methyltransf_11
DUF7080
Methyltransf_23
Thiolase_N
PS-DH
adh_short_C2
AlaDh_PNT_C
ACP_syn_III
Motif
Other DBs
NCBI-GeneID:
105552471
NCBI-ProteinID:
XP_011853578
Ensembl:
ENSMLEG00000027411
UniProt:
A0A2K5XVF5
LinkDB
All DBs
Position
Unknown
AA seq
2510 aa
AA seq
DB search
MEEVVIAGMSGKLPESENLQEFWDNLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRF
DASFFGVHPKQAHTMDPQLRLLLEVTYEAIVDAGINPTSLRGTHTGVWVGVSGSEASEAL
SRDPETLVGYSMVGCQRAMMANRLSFFFDFKGPSIALDTACSSSMVALQSAYQAISSGQC
PAAIVGGINVLLKPNTSVQFLRLGMLSPEGTCKAFDAEGNGYCRSEGVVAVLLTKKSLAR
RVYATILNAGTNTDGCKEQGVTFPSGEAQEQLIRSLYQSAGVAPESFEYIEAHGTGTKVG
DPQELNGIARALCATRQEPLLVGSTKSNMGHPEPVSGLAALAKVLLSLEHGLWAPNLHFH
SPHPEIPALLDGRLQVVAQPLPVRGGNVGINSFGFGGSNVHVILRPHTQPPPAPAPHASL
PRLLRASGRTPEAVQELLEQGLQHSQELAFLSMLNDIAAIPTTAMPFRGYAVLGGEHGGP
EVQQVPAGERPLWFICSGMGTQWRGMGLSLMRLDRFRDSILRSDEAVKPFGLKVSQLLLS
MDESTFDDIVHAFVSLTAIQIGLIDLLSCMGLRPDGIIGHSLGEVACGYADGCLSQEEAV
LAAYWRGQCIKEAHLPPGAMAAVGLSWEECKQRCPPGVVPACHNSKDTVTISGPQASVFE
FMEQLRKEGVFAKEVRTGGMAFHSYFMEAIAPPLLQALKKVIREPKPRSARWLSTSIPEA
QWHSSLARTSSAEYNVNNLVSPVLFQEALGHVPEHAVVLEIAPHALLQAVLKRGLKPGCT
IIPLMKKDHRDNLEFFLTGIGRLHLSGIDANPNALFPPVEFPAPRGTPLISPLIKWDHSL
AWDVPAAEDFPNGSGSPSAAVYNIDTSPESPDHYLVDHTIDGRVIFPATGYLCIAWKTLA
RALGVAVEQLPVVFEDVVLHQATILPKTGTVSLEVRLLEASRAFEVSQNGNLIVSGKVYQ
WEDPDPRLFNHPESPTPNPEEPLFLTQAEVYKELRLRGYDYGPHFHGILEASLEGESGRL
LWKDNWVSFLDAMLQISILGSAKRSLHLPTRITAIHIDPATHRQKLYTLQDDAQVADVVV
SRWLSITVAGGVHMSRVHTESAPRRQQDQQVPILEKFCFTPHVEEGCLSERAALQKELQL
CKGLAQALQTKVTQQGLRMVVPGLDGAQVPQDPLQQGLPQLLSAACRLQLNGNLQLELAQ
VLAQKRPELSEDPLLSGLLDSPALRACLDTAVENMPSRKMKVVEVLAGHGHLYSRIPGLL
GAQPLLQLSYTATDRHPQALEAAEAQLQQHDIAQGQWDPADPAPSTLGSTDLLVCNCAVA
ALGDPASALSNMVATLREGGFLLLHTLLRGHPLGETVAFLTSAEPQYGQGILSQDAWESL
FSGVSLRLVGLKKSFYGSALFLCRRPAPQDSPIFLPVDDTSFRWVESLKGILADEDSSRP
VWLKAVNCATSGVVGLVNCLRQEPGGHRLRCVLLSNLSSTSRVPEVDPGSAELQKVLQGD
LVMNVYRDGAWGAFRHFLLEEDKPEEPTAHAFVTTLTRGDLSSIRWVCSSLRHAQPSRPG
AQLCTVYYASLNFRDIMLATGKLSPEAIPGKWASQDNLLGMEFSGRDPSGKRVMGLVPAE
GLATSVLLSPDFLWDVPSNWTLEEAASVPVVYCTAYYSLVVRGRVRPGETVLIHSGSGGV
GQAAIAIALSLGCRVFTTVGSSEKRAYLQARFPQLDSTSFANSRDTSFEQHVLRHTGGKG
VDLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSQNHPLGMAIFLKNVTFHGILLDALL
DGSAEWQEVAALLQAGIRDGVVQPLKCTVFPGAQVEDAFRYMAQGKHIGKVLVQVLAEEP
EAVLKGAKPTLMSAISKTFCPAYKSYIIAGGLGGLGLELAQWLIQRGAQKLVLTSRSGVR
TGYQAKQVRQWRRQGVQVLVSTSNISSLEGARGLIAEAAQLGPVGGIFNLTMVLRDAMLE
NQTPEFFQDVCKPKYSGTLNLDRVTREACPELDYFVVFSSVSSGRGNAGQSNYGFANSAM
ERICEKRRHEGLPGLAVQWGAIGDVGILADTVNINATVIGGTLPQRVASCLEVLDLFLNQ
PHMVLSSFVLAEKAAAYRDRDGEQDLVKAVAHILGIRDLAAINLDSSLADLGLDSLMSVE
VRQTLERELNLVMSMREVRQLTLRRLQELSLKADAANELASPTPKEDGPARQQTQLNLRS
LLVNPEGPTLMRLNSVQSSERPLFLVHPIEGSTTVFHSLASRLSIPTYGLQCTRAAPLDS
IHSLAAYYIDCIRQVQPEGPYRVAGYSYGACVAFEMCSQLQAQQNPAPTHNSLFLFDGSH
TYVLAYTQSYRAKLTPGCEAEAETEAICFFVQQFTDMEHNRVLEALLPLKGLEERVAAAV
DLIIKSHQSLDRQELSFAALSFYYKLRAAEQYTPKAKYHGNVMLLRAKTGGAYGEDLGAD
YNLSQVCDGKVSVHVIEGDHRTLLEGSGLESIVSIIHSSLAEPRVSVREG
NT seq
7533 nt
NT seq
+upstream
nt +downstream
nt
atggaggaggtggtgattgccggtatgtccgggaagcttccggagtcggagaacttgcag
gagttctgggacaacctcatcggcggtgtggacatggttacggacgatgaccgtcgctgg
aaggcggggctctacggcctgccccggcggtccggcaaattgaaggacctgtctaggttc
gatgcctccttctttggagtccaccccaagcaggcacacaccatggaccctcagctgcgg
ctgctgctggaagtcacctatgaggccatcgtggatgcaggcatcaacccaacttcactc
cgagggacacacactggcgtctgggtgggcgtgagcggctctgaggcctcggaggccctg
agccgcgaccctgagacgctcgtgggctacagcatggtgggctgccagcgagccatgatg
gccaaccggctctccttcttcttcgacttcaaagggcccagcatcgccctggacacggcc
tgctcctccagcatggtggccctgcagagcgcctaccaggccatctccagcgggcaatgc
cctgccgccatcgtggggggcatcaatgtcctgctgaagcccaacacctccgtgcagttc
ctgcggctggggatgctaagccccgagggcacctgcaaggccttcgacgcagaggggaac
gggtactgccgctcggagggtgtggtagccgtcctgctgaccaagaagtccctggcccgg
cgggtgtacgccaccatcctgaacgccggcaccaatacagacggctgcaaggagcaaggc
gtgaccttcccctctggagaggcccaggagcagctcatccgttccttgtaccagtcggct
ggagtggcccctgagtcatttgagtacatcgaagcccacggcacaggcaccaaggtgggt
gacccccaggagctgaatggcatcgcccgagccctgtgcgccacccgccaggagccactg
ctcgtcggctccacgaagtccaacatggggcacccggagccagtctcggggctggcagcc
ctggccaaggtgctgctgtccctggagcacgggctctgggcccccaacctgcacttccac
agcccccaccctgagatcccagcactgttggatgggcggctgcaagtggtggcccagccc
ctgcctgtccgtggtggcaacgtgggcatcaactcctttggctttgggggttccaacgtg
cacgtcatcctgaggccccacacgcagccgcccccggcacccgccccacacgccagcctg
ccccgtctgctgcgggctagtggacgcacccctgaggccgtgcaggagctgctggagcag
ggcctccagcacagccaggagctggctttcctgagcatgctgaatgacatcgcggccatc
cccaccacggccatgcccttccgcggctatgccgtgctgggtggcgagcacggtggccca
gaggtgcagcaggtgcccgctggcgagcgcccgctctggttcatctgctctgggatgggc
acgcagtggcgcgggatggggctgagcctcatgcgcctggaccgcttccgagactccatc
ctgcgctccgacgaggctgtgaagccgttcggcctgaaggtgtcgcagctgcttctgagc
atggacgagagcacctttgacgacatcgtccacgccttcgtgagcctgactgccatccag
ataggcctgatagacctgctgagctgcatggggctgagaccagacggcatcatcggccac
tctctgggggaggtggcctgtggctacgctgacggctgcctgtcccaggaggaggctgtc
ctcgctgcctactggagggggcaatgcatcaaagaagcccatctcccgccgggcgccatg
gcagccgtgggcttgtcctgggaggagtgtaaacagcgctgccccccgggcgtggtgccc
gcctgccacaactccaaggacacagtcaccatctcgggacctcaggcctccgtgttcgag
ttcatggagcagctacggaaggagggcgtgtttgccaaggaggtgcggaccggcggcatg
gccttccactcctacttcatggaggccatcgcacccccactgctgcaggcgctcaagaag
gtgatccgggagccgaagccacgttcagcccgctggctcagcacctccatccccgaggcc
cagtggcacagcagcctggcacgcacgtcctccgcggagtacaatgtcaacaacctggtg
agccctgtgctgttccaggaggctctgggtcacgtgcctgagcacgcagtggtgctggag
atcgcgccccacgccctgctgcaggctgtcctgaagcgtggcctgaagccgggctgcacc
atcatccccctgatgaagaaggatcacagggacaacctggagttcttcctcaccggcatc
ggcaggctgcacctctcaggcatcgacgccaaccccaatgccctgttcccgcctgtggag
ttcccagctccccgaggaacccccctcatctccccactcatcaagtgggaccacagcctg
gcctgggacgtgccagctgccgaggacttccccaacggctctggttccccctcggccgcc
gtctacaacatcgacaccagccccgagtctcccgaccactacctggtggatcacaccatc
gacggccgcgtcatcttccccgccactggctacctgtgcatagcgtggaagacgctggcc
cgggccctgggcgtggccgtggagcagctgcctgtggtgtttgaggacgtggtgctgcac
caggccaccatcctgcccaagactgggaccgtgtccctggaggtacggctcctggaggcc
tcccgcgccttcgaggtgtcacagaacggcaacctgatagtgagtgggaaggtgtaccag
tgggaggaccctgaccccaggctcttcaaccacccggaaagccccacccccaaccccgag
gagccccttttcctgacccaggctgaggtttacaaggagctgcgtctgcgtggctacgac
tatggccctcacttccatggcatcctggaggccagcctggaaggtgagtcggggaggctg
ctgtggaaggacaactgggtgagcttcctggacgccatgctgcagatttccatcctgggc
tcggccaagcgcagcctgcacctgcccacccgcatcaccgccatccacatcgaccctgcc
acccacaggcagaagctgtacacgctgcaggacgacgcccaagtggctgacgtggtggtg
agcaggtggctgagcatcacagtggccggaggcgtccacatgtcccgtgtccacaccgag
tcggccccgcggcggcagcaggaccagcaggtgcccatcctggagaagttttgcttcacg
ccccacgtggaggaggggtgcctgtctgagcgtgctgccctgcagaaggagctgcagcta
tgcaaggggctggcgcaggcactacagaccaaggtgacccagcaggggctgaggatggtg
gtgcctggactggatggggcccaggtcccccaggaccccctacagcagggactgccccag
ctgctgtcagctgcctgcaggcttcagctcaacgggaacctgcagctggagctggcacag
gtgctggcccagaagaggcctgagctgtcagaggaccctctgctcagcggcctcctggac
tccccggcgctcagggcctgcctggacactgctgtggagaacatgcccagccggaagatg
aaggtggtggaggtgctggctggccacggccacctgtattcccgcatcccaggcctgctt
ggcgcccagcccctgctgcagctgagctacacggccaccgaccgccaccctcaggccctg
gaggctgccgaggcccagctgcagcagcacgacattgcccagggccagtgggaccctgcg
gaccctgcccccagcaccctgggcagcactgacctcctggtgtgcaactgtgccgtggct
gcccttggggacccggcctcagctctcagcaacatggtggctaccctgagagaagggggc
ttcctgctgctgcacaccctgctccgggggcaccccctcggggagaccgtggccttcctc
acctccgctgagcctcagtacggccagggcatcctgagccaggacgcgtgggagagcctc
ttctccggtgtgtcactgcgcctggtgggcctgaagaagtccttctacggctctgcactc
ttcctgtgccgccggcccgccccgcaggacagccccatcttcctgccggtggacgacacc
agcttccgctgggtggagtcgctgaagggcatcctggctgacgaagactcctcccggccc
gtgtggctgaaggccgtcaactgtgccacctcgggcgtggtgggcttggtgaactgtctc
cgccaagagcccggcgggcaccgcctccggtgcgtgctgctgtccaacctcagcagcacc
tcccgcgtcccggaggtggacccgggctccgcagagctgcaaaaggtgttgcagggagac
ctggtgatgaacgtctaccgcgacggggcctggggggccttccgccacttcctgctggag
gaggacaagcctgaggagcccacggcacacgcctttgtgaccaccctcacccggggggac
ctgtcctccatccgctgggtctgctcctcgctgcgccatgcccagccctcccgccccggc
gcccagctctgcacggtctactacgcctccctcaacttccgcgacatcatgctggccacc
ggcaagctgtcccctgaggccattccagggaagtgggcctcccaggacaacctgctaggc
atggagttctcgggccgagaccccagtggcaaacgtgtgatgggactggtgcccgccgag
ggcctggccacctctgtcctgctgtcaccggactttctctgggacgtgccatccaactgg
accctggaggaggcggcctcagtgcccgtcgtctactgcacagcctactactcgctggtg
gtgcgcgggcgggtgcgccccggggagacagtgctcatccactcgggctccggcggcgtg
ggccaagccgccatcgccatcgccctcagtctgggctgccgcgtcttcactaccgtgggg
tcatccgagaagcgggcatacctccaggccaggttcccccagcttgacagcaccagcttc
gccaactcccgggacacatcattcgagcagcacgtcctgcggcacacgggcgggaagggt
gttgacctggtcttgaactccttggcggaagagaagctgcaggccagcgtgaggtgcttg
gctcagcacggtcgcttcctggaaattggcaaattcgacctttctcagaaccacccactt
ggcatggccatcttcctgaagaacgtgacattccacgggatcctactggatgcactcttg
gatggcagtgctgaatggcaggaggtggcggcgctcctgcaggccggcatccgggacggg
gtggtacagcccctcaagtgcacagtgttccctggggcccaggtggaggacgccttccgc
tacatggcccaggggaagcacatcggcaaagtcctcgtgcaggtgcttgcggaggagccg
gaggcagtgctgaagggggccaaacccacgctgatgtcggccatctccaagaccttctgc
ccggcctacaagagctacatcatcgctggaggtctgggtggcctcggcctggagttggca
cagtggctgatccagcgtggggcgcagaagctcgtgttgacctctcgctccggggtccgg
acaggctaccaggccaagcaggtccgccagtggaggcgccagggcgtgcaggtgctggtg
tccaccagcaacatcagctccctggagggggcccggggccttatcgccgaggcggcgcag
ctcgggcccgtgggcggcatcttcaacctaaccatggtcttgagagacgccatgctggag
aaccagaccccggagttcttccaggacgtctgcaagcccaagtacagtggcaccctgaac
ctggacagggtgacccgggaggcgtgccctgagctggactactttgtggtcttctcctct
gtgagctccgggcgcggcaatgccggacagagcaactatggctttgccaactctgccatg
gagcgcatctgcgagaaacgccggcacgaaggcctcccaggcctggccgtgcagtggggc
gccatcggcgacgtgggcattttggcggacacagtgaacatcaacgccacggtcatcggt
ggcacgctgcctcagcgtgtggcctcctgcctggaggtgctggacctcttcctgaaccag
ccccacatggtcctgagcagtttcgtgctggctgagaaggctgcggcctacagggacagg
gacggcgagcaggacctggtgaaggctgtggcacacatcctgggcatccgcgatttggct
gccatcaacctggacagctcactggcggacctgggcctggactcgctaatgagcgtggag
gtgcgccagacgctggagcgcgagctcaacctggtgatgtcgatgcgcgaggtgcggcag
ctaacgctccggagactgcaggagctgtccttgaaggcggatgcggccaacgagctggca
tcccccacgcccaaggaggacggtccggcccggcagcagactcagctgaacctgcgctct
ctgctggtgaaccccgagggccccaccctgatgcggctcaattcagtgcagagctctgag
cgacccctattcctggtgcacccaatcgagggctccaccaccgtgttccacagcctggcc
tcccggctcagcatccctacctatggcctgcagtgcacccgagctgcgcccctcgacagc
atccacagcctggctgcctactacatcgactgcatcaggcaggtgcagcccgagggcccc
taccgcgtggccggctactcctatggggcctgcgtggcctttgaaatgtgctcccagctg
caggcccagcagaacccagcccccacccacaacagcctcttcctgttcgatggctcgcac
acttacgtactggcctacacccagagctaccgggcaaagctgaccccaggctgtgaggct
gaggccgagacggaggccatatgcttcttcgtgcagcagttcacggacatggagcacaac
agggtgctggaggcgctgctgccgctgaagggcctggaggagcgcgtggcggctgccgtg
gacctgatcatcaagagccaccagagcctggaccgccaggagctgagcttcgcggccctg
tccttctactacaagctgcgcgccgccgagcagtacacgcccaaggccaagtaccatggc
aacgtgatgctgctgcgtgccaagacgggtggcgcctacggcgaggatctgggcgcggac
tacaacctctcccaggtatgcgatgggaaagtgtctgtccacgtcatcgagggtgaccac
cgcacgctgctggagggcagcggcctggagtccatcgtcagcatcatccacagctccctg
gctgagccacgtgtgagcgtgcgggagggctag
DBGET
integrated database retrieval system
