Mandrillus leucophaeus (drill): 105553071
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Entry
105553071 CDS
T08763
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
mleu
Mandrillus leucophaeus (drill)
Pathway
mleu01524
Platinum drug resistance
mleu03440
Homologous recombination
mleu03460
Fanconi anemia pathway
mleu04120
Ubiquitin mediated proteolysis
mleu04151
PI3K-Akt signaling pathway
mleu05206
MicroRNAs in cancer
mleu05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
mleu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
105553071 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
105553071 (BRCA1)
03460 Fanconi anemia pathway
105553071 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
105553071 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
105553071 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
105553071 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
105553071 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
mleu01009
]
105553071 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
mleu04121
]
105553071 (BRCA1)
03036 Chromosome and associated proteins [BR:
mleu03036
]
105553071 (BRCA1)
03400 DNA repair and recombination proteins [BR:
mleu03400
]
105553071 (BRCA1)
Enzymes [BR:
mleu01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
105553071 (BRCA1)
Protein phosphatases and associated proteins [BR:
mleu01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
105553071 (BRCA1)
Ubiquitin system [BR:
mleu04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
105553071 (BRCA1)
Multi subunit type E3
BRCC complex
105553071 (BRCA1)
Chromosome and associated proteins [BR:
mleu03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
105553071 (BRCA1)
DNA repair and recombination proteins [BR:
mleu03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
105553071 (BRCA1)
BRCA1-A complex
105553071 (BRCA1)
BRCA1-B complex
105553071 (BRCA1)
BRCA1-C complex
105553071 (BRCA1)
BRCA complex
105553071 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
105553071 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
BRCT
BRCT_2
RTT107_BRCT_5
Motif
Other DBs
NCBI-GeneID:
105553071
NCBI-ProteinID:
XP_011854407
LinkDB
All DBs
Position
Unknown
AA seq
688 aa
AA seq
DB search
SLQESTRFSQLVEELLKIIHAFQLDTGLQFANSYNFAKKENHSPEHLKDEVSIIQSMGYR
NRAKRLLQSEPENPSLQETSLSVPLSNLGIVRTLRRKQRIQPQKKSVYIELGSDSSEDTV
NKATYCSVGDQELLQITPQGTRDETSLDSAKKAACEFSEKDITNAEHHQSSNNDLNTTEK
HATERHPEKYQGEAASGYESETSVSEDCSRLSSQSEILTTQQRDTMQDNLIKLQQEMAEL
EAVLEQHGSQPSNSYPSIITDSSALEDLRNPEQSTSEKVLTSQKSSEYPINQNPEGLSAD
KFEVSADSSTSKNKEPGVERSSPSKCQSLEDRWYVHSSSGSLQNGNYPSQEELIKVVDVE
TQQLEKSGPHDLMELSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRAPESAHVGSIPS
STSALKVPQWQVAESAQSPAAAHNTNTAGCNAMEESVSREKPKLTASTERVNKRMSLVVS
GLTPEEFMLVYKFARRYHIALTNLISEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVS
YFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESPDRKIFRGLEICCYGPFTNM
PTDQLEWMVQLCGASVVKELSSFTLGTGFHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTR
EWVLDSVALYQCQELDTYLIPQIPHSHY
NT seq
2068 nt
NT seq
+upstream
nt +downstream
nt
aagcctacaagaaagtacaagatttagtcaacttgttgaagagctattgaaaatcattca
tgcttttcagcttgacacaggtttgcagtttgcaaacagttacaattttgcaaaaaagga
aaatcactctcctgaacatctaaaagatgaagtttctatcatccaaagtatgggctacag
aaaccgtgccaaaagacttctacagagtgaacccgaaaatccttccttgcaagaaaccag
tctcagtgtcccactctctaaccttggaattgtgagaactctgaggagaaagcagcggat
acaacctcaaaagaagtctgtctacattgaactgggatctgattcttctgaagatacggt
taataaggcaacttattgcagtgtgggagatcaagaattgttacaaatcacccctcaagg
aaccagggatgaaaccagtttggattctgcaaaaaaggctgcttgtgaattttctgagaa
ggatataacaaatgctgaacatcatcagtccagtaataatgatttgaacaccactgagaa
acatgcaactgagaggcatccagaaaagtatcagggtgaagcagcatctgggtatgagag
tgaaacaagtgtctctgaagactgctcaaggctctcctctcagagcgaaattttaaccac
tcagcagagggataccatgcaagataacctaataaagctccagcaggaaatggctgaact
agaagctgtgttagaacagcacggaagccagccttctaacagctacccttccatcataac
tgactcttctgcccttgaggacctgcgaaatccagaacaaagcacatcagaaaaagtatt
aacttcacagaaaagtagtgaatatcctataaaccagaatccagaaggcctttctgctga
caagttcgaggtatctgcagatagttctaccagtaaaaataaagaaccaggagtggaaag
gtcatccccttctaaatgccagtcattagaggataggtggtatgtgcacagtagctctgg
gagtcttcagaatggaaattacccatctcaagaggagctcattaaggttgttgatgtgga
gacgcaacaactggaaaagtctgggccacacgatttgatggaactatcttacttgccaag
gcaagatctagagggaaccccttacctggaatctggaatcagtctcttctctgatgaccc
tgaatctgatccttccgaagacagagccccagagtcagctcatgttggcagcataccatc
ttcaacctctgcattgaaagtaccccagtggcaagttgcagaatctgcccagagtccagc
tgctgctcataatactaatactgctgggtgtaatgcaatggaagaaagtgtgagcaggga
gaagccaaaattgacagcttcaacagaaagggtcaacaaaagaatgtccttggtggtgtc
tggcctgaccccagaagaatttatgctcgtgtacaagtttgccagaagataccacatcgc
tttaactaatctaattagtgaagagactactcatgtcgttatgaaaacagatgctgagtt
tgtgtgtgaacggacgctgaaatattttctgggaattgcgggaggaaaatgggtagttag
ctatttctgggtgacccagtctattaaagaaagaaaaatgctgaatgagcatgattttga
agtcagaggagatgtggtcaatggaagaaaccaccaaggtccaaagcgagcaagagaatc
cccagacagaaagatcttcagggggctagaaatctgttgttatgggcccttcaccaacat
gcccacagatcaactggagtggatggtacagctgtgtggtgcttctgtggtgaaggagct
ttcatcattcacccttggcacaggtttccacccaattgtggttgtgcagccagatgcctg
gacagaggacaatggcttccatgcaattgggcagatgtgtgaggcacctgtggtgacccg
agagtgggtgttggacagtgtagcactctaccagtgccaggagctggacacctacctgat
accccagatcccccacagccactactga
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