Mandrillus leucophaeus (drill): 105553689
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Entry
105553689 CDS
T08763
Symbol
EIF2AK3
Name
(RefSeq) eukaryotic translation initiation factor 2-alpha kinase 3
KO
K08860
eukaryotic translation initiation factor 2-alpha kinase 3 [EC:
2.7.11.1
]
Organism
mleu
Mandrillus leucophaeus (drill)
Pathway
mleu04137
Mitophagy - animal
mleu04140
Autophagy - animal
mleu04141
Protein processing in endoplasmic reticulum
mleu04210
Apoptosis
mleu04932
Non-alcoholic fatty liver disease
mleu05010
Alzheimer disease
mleu05012
Parkinson disease
mleu05014
Amyotrophic lateral sclerosis
mleu05020
Prion disease
mleu05022
Pathways of neurodegeneration - multiple diseases
mleu05160
Hepatitis C
mleu05162
Measles
mleu05168
Herpes simplex virus 1 infection
mleu05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mleu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
105553689 (EIF2AK3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
105553689 (EIF2AK3)
04137 Mitophagy - animal
105553689 (EIF2AK3)
09143 Cell growth and death
04210 Apoptosis
105553689 (EIF2AK3)
09160 Human Diseases
09172 Infectious disease: viral
05160 Hepatitis C
105553689 (EIF2AK3)
05162 Measles
105553689 (EIF2AK3)
05168 Herpes simplex virus 1 infection
105553689 (EIF2AK3)
09164 Neurodegenerative disease
05010 Alzheimer disease
105553689 (EIF2AK3)
05012 Parkinson disease
105553689 (EIF2AK3)
05014 Amyotrophic lateral sclerosis
105553689 (EIF2AK3)
05020 Prion disease
105553689 (EIF2AK3)
05022 Pathways of neurodegeneration - multiple diseases
105553689 (EIF2AK3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
105553689 (EIF2AK3)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
105553689 (EIF2AK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mleu01001
]
105553689 (EIF2AK3)
Enzymes [BR:
mleu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
105553689 (EIF2AK3)
Protein kinases [BR:
mleu01001
]
Serine/threonine kinases: Other
PEK family [OT]
105553689 (EIF2AK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kinase-like
Kdo
ABC1
OATP
Motif
Other DBs
NCBI-GeneID:
105553689
NCBI-ProteinID:
XP_011855212
Ensembl:
ENSMLEG00000009953
UniProt:
A0A2K5XGP0
LinkDB
All DBs
Position
Unknown
AA seq
964 aa
AA seq
DB search
MIIPSLDGALFQWDRDRESMETVPFTVESLLESSYKFGDDVVLVGGKSLTTYGLSACSGK
VRYICSALGCRQWDSDEMEQEEDILLLQRTQKTVRAVGPRSGNEKWNFSVGHFELRYIPD
METRAGFIESTFKPNENTEESKIISDVEEQEAAIMDIVIKVSVADWKVMAFSKKGGHLEW
EYQFCTPIASAWLLKDGKVIPISLFDDTSYTSNDDVLEDEEDIVEAARGATENSVYLGMY
RGQLYLQSSVRISEKFPTSPKALESVNNENAIIPLPTIKWKPLIHSPSRTPVLVGSDEFD
KCLSNDKFSHEEYSNGALSILQYPYDNGYYLPYYKRERNKRSTQITVRFLDNPNYNKNIR
KKDPVLLLHWWKEIVATILFCIVATTFIVRRLFHPHPHRQRKESETQCQTENKYDSVSGE
ANDSSWNDIKNSGYVSRYLTDFEPIQCLGRGGFGVVFEAKNKVDDCNYAIKRIRLPNREL
AREKVMREVKALAKLEHPGIVRYFNAWLEAPPEKWQEKMDEIWLKDASTDWPLSSPSPMD
APSVKIRRMDPFSTKEHVEIIAPSPERSRSFSVGISCDQTSSSESQFSPLEFSGMDHEDI
SESVDAAYNLQDSCLTDCDVEDGTMDGNDEGHSFELCPSEASPYVRSRERTSSSIVFEDS
GCDNASSKEEPKTNRLHIGNHCANKLTAFKPTSSKSSEATLSISPPRPTTLSLDLTKNTT
EKLQPSSPKVYLYIQMQLCRKENLKDWMNGRCTIEERERSMCLHIFLQIAEAVEFLHSKG
LMHRDLKPSNIFFTMDDVVKVGDFGLVTAMDQDEEEQTVLTPMPAYARHTGQVGTKLYMS
PEQIHGNSYSHKVDIFSLGLILFELLYPFSTQMERVRTLTDVRNLKFPPLFTQKYPCEYM
MVQDMLSPSPMERPEATNIIENAVFEDLDFPGKTVLRQRSRSLSSSGTKHSRQSNNSHSP
LPSN
NT seq
2895 nt
NT seq
+upstream
nt +downstream
nt
atgattattccttccctggatggagcactcttccagtgggaccgagaccgtgagagcatg
gaaacagttcctttcacagttgaatcacttctcgaatcttcttataaatttggagatgat
gttgttttggttggaggaaaatctctcactacatatggactcagtgcatgtagtggaaag
gtgaggtatatctgttcagctctaggttgtcgccaatgggatagtgatgaaatggaacaa
gaggaagacatcctgcttctacagcgtacccaaaaaactgttagagctgtcggacctcgc
agtggcaatgagaagtggaatttcagtgttggccactttgaacttcggtatattccagac
atggaaacgagagccggatttattgaaagcacctttaagcccaatgagaacacagaagag
tctaaaattatttcagatgtggaagaacaggaagctgccataatggacatagtgataaag
gtttcggttgctgactggaaagttatggcattcagtaagaagggaggacatctggaatgg
gagtaccagttttgtactccaattgcatctgcctggttacttaaggatgggaaagtcatt
cccatcagtctttttgatgatacaagttatacatctaatgatgatgttttagaagatgaa
gaagacattgtagaagctgccagaggagccacagaaaacagtgtttacttgggaatgtat
agaggccagctttatctgcagtcatcagtcagaatttcggaaaagtttcctacaagtccc
aaggctttggaatctgtcaataatgaaaacgcaattattcctttgccaacaatcaaatgg
aaacccttaattcattctccttccagaactcctgtcttggtaggatctgatgaatttgac
aaatgtcttagtaatgataagttttctcatgaagaatatagtaatggcgcactttcaatc
ttgcagtatccgtatgataatggttattatctaccgtactacaagagggaaaggaacaaa
cgaagcacacagattacagtcagattcctcgacaacccaaattacaacaagaatatccgc
aaaaaggatcctgttctcctcttacactggtggaaagaaatagttgcaacgattttgttt
tgtatcgtagcaacaacgtttattgtgcgcaggcttttccaccctcatcctcacaggcaa
aggaaggagtctgaaactcagtgtcaaactgaaaataaatatgattctgtaagtggtgaa
gccaatgacagtagctggaatgacataaaaaactctggatatgtatcacgatatctaact
gattttgagccaattcagtgcctgggacgtggtggctttggagttgtttttgaagctaaa
aacaaagtagatgactgcaattatgctatcaagaggattcgtctgcccaatagggaattg
gctcgggaaaaggtaatgcgagaagttaaagccttagccaagcttgaacacccaggcatt
gttagatatttcaatgcctggctcgaagcaccaccagagaagtggcaagaaaagatggat
gaaatttggctgaaagatgcaagcacagactggccactcagctctcctagcccaatggat
gcaccatcagttaaaatacgcagaatggatcctttctctacaaaagaacatgttgaaatc
atagctccttcaccagaaagaagcaggtctttttcagtagggatttcctgtgaccagaca
agttcatctgagagccagttctcaccactggaattctcaggaatggaccatgaggacatc
agtgagtcagtggatgcagcatacaacctccaggacagctgccttactgactgtgatgtg
gaagatggtactatggatggcaatgatgaggggcactcctttgaactttgtccttctgaa
gcttctccttatgtaaggtcaagggagagaacctcctcttcgatagtatttgaagattct
ggctgtgataatgcttccagtaaagaagagcccaaaactaatcgattgcatattggcaac
cattgtgcaaataaactaactgctttcaagcccaccagtagcaaatcttctgaagctaca
ttatctatttctcctccaagaccaaccactttaagtttagatctcactaaaaacaccaca
gaaaaactccaacccagttccccaaaggtgtatctttacattcaaatgcagctgtgcaga
aaagaaaacctcaaagactggatgaatggacgatgtaccatagaggagagagagcggagc
atgtgtctgcacatcttcctgcagatcgcagaggcagtggagtttcttcacagtaaagga
ctgatgcacagggacctcaagccatccaacatattctttacaatggatgatgtggtcaag
gttggagactttgggttagtgactgcaatggaccaggatgaggaagagcagacggttctg
accccaatgccagcttatgccagacacacaggacaagtagggaccaaactgtatatgagc
ccagagcagattcatggaaacagctattctcataaagtggacatcttttctttaggcctg
attctatttgaattgctgtacccattcagcactcagatggagagagtcaggaccttaact
gatgtaagaaatctcaaatttccaccattatttactcagaaatatccttgtgagtatatg
atggttcaagacatgctctctccatcccccatggaacgacctgaagctacaaacatcatt
gaaaatgctgtgtttgaggacttggactttccaggaaaaacagtgctcagacagaggtcc
cgctccttgagttcatcgggaacaaaacattcaagacagtccaacaactcccatagccct
ttgccaagcaattag
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