Myotis lucifugus (little brown bat): 102427630
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Entry
102427630 CDS
T07795
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
mlf
Myotis lucifugus (little brown bat)
Pathway
mlf04120
Ubiquitin mediated proteolysis
mlf04144
Endocytosis
mlf04330
Notch signaling pathway
mlf04668
TNF signaling pathway
mlf04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
mlf00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
102427630 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
102427630 (ITCH)
04668 TNF signaling pathway
102427630 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
102427630 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
102427630 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mlf04131
]
102427630 (ITCH)
04121 Ubiquitin system [BR:
mlf04121
]
102427630 (ITCH)
Enzymes [BR:
mlf01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
102427630 (ITCH)
Membrane trafficking [BR:
mlf04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
102427630 (ITCH)
Ubiquitin system [BR:
mlf04121
]
Ubiquitin ligases (E3)
HECT type E3
102427630 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
102427630
NCBI-ProteinID:
XP_006089485
Ensembl:
ENSMLUG00000004798
LinkDB
All DBs
Position
Unknown
AA seq
865 aa
AA seq
DB search
MCDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPMSKLHFRVWSHQTLKSDVLLGTAALDIYETLKSNNMKLEKVVVTL
QLVGDKEPTETIGDLSVCLDGLQLESEVVTNGEATCSENVKGASQNDDGSRPKEETRVNT
NGSDDPEDAGSGENSKVNGNNSPSLSNGGVKPSRPPRPSRPPPPTPRRPASVNGSPSATS
ESDGSSTGSLPPTNTNSNTSEGATSGLIIPLTISGGSGPRPLNPVPQAPLPPGWEQRVDQ
HGRVYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYE
QWQLQRSQLQGAMQQFNQRFIYGNQDLFATTQNKEFDPLGPLPPGWEKRTDGNGRVYFVN
HNTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDN
GPQIAYVRDFKAKFQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLW
VIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYF
RFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEE
CGLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFF
EGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHTIYRHYTRTSKQIMWFWQFVKE
IDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLP
PYKSYEQLKEKLLFAIEETEGFGQE
NT seq
2598 nt
NT seq
+upstream
nt +downstream
nt
atgtgtgacagtggatcacagcttggttcaatgggtagcctgaccatgaaatcacaactt
cagatcactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttggaccaagt
ccttatgtggaagttacagtagatggacagtcaaagaagacagaaaaatgtaacaataca
aacagtcccaaatggaagcaaccccttacagttatcgtcacccctatgagtaaattacat
tttcgcgtgtggagtcaccagacactgaaatctgatgttttattgggaactgctgcacta
gatatctatgaaacattaaagtcaaacaatatgaaacttgagaaagtagttgtgacttta
cagcttgtaggtgacaaagaaccaacagagacaataggagacttgtcagtttgtcttgat
gggctgcagttagaatctgaagttgttaccaatggtgaagctacatgttcagaaaatgtt
aaaggtgcttcacagaatgatgatggctccaggcccaaggaggaaacaagagtgaacaca
aatggatcagacgaccctgaggatgcagggtctggtgaaaatagtaaggtcaatgggaat
aattctccatcactctcaaatggcggtgttaagccttctagacctccaagaccttcacga
ccacctccacctaccccacgtagaccagcttctgttaatggttcgccttctgccacttct
gaaagtgatggctccagtacaggctctctgcctccaacaaatacaaattcaaatacgtct
gagggagcaacatctggattaataattcctcttactatatctggaggctcgggccctagg
ccattaaatcctgtaccccaagctccactaccacctggttgggagcagagagtggaccag
cacgggcgagtttactatgtagatcatattgaaaaaagaacaacgtgggatagaccagaa
cctctacctcctggctgggaacgcagggttgacaacatgggacgtatttattatgttgac
catttcacaagaacaacaacgtggcagaggccaacattggaatccgtccggaactatgaa
cagtggcagctccagcgtagtcagcttcaaggagcaatgcagcagtttaatcagagattc
atttatgggaatcaagatttgtttgcaacaacacaaaataaagaatttgatcctcttggt
cccctgccacctggatgggaaaagagaacagacggcaatggtagagtatattttgtcaac
cacaacactcgtattacacaatgggaagaccccagaagtcaaggtcaattaaatgaaaag
cccttacctgaaggctgggaaatgagattcacagtggatggaattccatattttgtggac
cacaatagaagaacaaccacctatatagatccccgcactggaaaatctgccctagacaat
ggaccccaaatagcctatgtacgggactttaaggcaaagtttcagtatttccggttctgg
tgtcagcaactggccatgccacagcacataaagattacagtaacaagaaaaacattgttt
gaggattcctttcaacagataatgagcttcagtccccaagatctgcgaagacgtttgtgg
gtgatttttccaggagaagaaggtttagattatggaggtgtagcaagggaatggttcttt
cttttgtcacatgaagtgttgaacccaatgtattgcctgtttgaatatgcagggaaggat
aactactgcttgcagataaaccccgcttcttatatcaatccagatcacctgaaatatttt
cgttttattggcaggtttattgccatggctctgttccatgggaaattcatagatacaggt
ttttccttgccattctacaagcgtatcttgaacaaaccagttggactcaaggatttagaa
tctattgatccagaattttacaattctctcatctgggttaaagaaaacaatattgaggaa
tgtggtttggaaatgtacttctccgtcgataaagaaattttaggtgaaatcaagagtcat
gatttgaaacccaatggtggcaatattcttgtaacagaagaaaataaagaggaatatatc
agaatggtagctgaatggcgattgtctcgaggtgttgaagaacagacacaagctttcttt
gagggtttcaatgaaattcttccccagcagtatttgcagtactttgatgcaaaggagtta
gaggtccttttatgtggaatgcaagagattgatttgaatgactggcaaagacataccatc
taccgtcattatactaggacaagcaaacaaataatgtggttttggcagtttgttaaagaa
attgataatgagaagagaatgagacttctacagtttgttactggaacctgccgattacca
gttggaggatttgctgacctcatggggagcaatggacctcaaaaattctgcattgaaaaa
gttgggaaagaaaactggttacccagaagtcatacctgttttaaccgcctggacctacca
ccctataagagctatgagcaactgaaggaaaagctgttatttgccattgaagaaacagaa
ggatttggacaagagtaa
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