Myotis lucifugus (little brown bat): 102439369 Help Entry 102439369         CDS       T07795                                  Symbol CASP8 Name (RefSeq) LOW QUALITY PROTEIN: caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism mlf  Myotis lucifugus (little brown bat) Pathway mlf01524   Platinum drug resistance mlf04115   p53 signaling pathway mlf04210   Apoptosis mlf04215   Apoptosis - multiple species mlf04217   Necroptosis mlf04620   Toll-like receptor signaling pathway mlf04621   NOD-like receptor signaling pathway mlf04622   RIG-I-like receptor signaling pathway mlf04623   Cytosolic DNA-sensing pathway mlf04625   C-type lectin receptor signaling pathway mlf04657   IL-17 signaling pathway mlf04668   TNF signaling pathway mlf04932   Non-alcoholic fatty liver disease mlf04936   Alcoholic liver disease mlf05010   Alzheimer disease mlf05016   Huntington disease mlf05022   Pathways of neurodegeneration - multiple diseases mlf05132   Salmonella infection mlf05134   Legionellosis mlf05142   Chagas disease mlf05145   Toxoplasmosis mlf05152   Tuberculosis mlf05160   Hepatitis C mlf05161   Hepatitis B mlf05162   Measles mlf05163   Human cytomegalovirus infection mlf05164   Influenza A mlf05165   Human papillomavirus infection mlf05167   Kaposi sarcoma-associated herpesvirus infection mlf05168   Herpes simplex virus 1 infection mlf05169   Epstein-Barr virus infection mlf05170   Human immunodeficiency virus 1 infection mlf05200   Pathways in cancer mlf05203   Viral carcinogenesis mlf05416   Viral myocarditis mlf05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mlf00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     102439369 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     102439369 (CASP8)    04215 Apoptosis - multiple species     102439369 (CASP8)    04217 Necroptosis     102439369 (CASP8)    04115 p53 signaling pathway     102439369 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     102439369 (CASP8)    04621 NOD-like receptor signaling pathway     102439369 (CASP8)    04622 RIG-I-like receptor signaling pathway     102439369 (CASP8)    04623 Cytosolic DNA-sensing pathway     102439369 (CASP8)    04625 C-type lectin receptor signaling pathway     102439369 (CASP8)    04657 IL-17 signaling pathway     102439369 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102439369 (CASP8)    05203 Viral carcinogenesis     102439369 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     102439369 (CASP8)    05161 Hepatitis B     102439369 (CASP8)    05160 Hepatitis C     102439369 (CASP8)    05164 Influenza A     102439369 (CASP8)    05162 Measles     102439369 (CASP8)    05168 Herpes simplex virus 1 infection     102439369 (CASP8)    05163 Human cytomegalovirus infection     102439369 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     102439369 (CASP8)    05169 Epstein-Barr virus infection     102439369 (CASP8)    05165 Human papillomavirus infection     102439369 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     102439369 (CASP8)    05134 Legionellosis     102439369 (CASP8)    05152 Tuberculosis     102439369 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     102439369 (CASP8)    05142 Chagas disease     102439369 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     102439369 (CASP8)    05016 Huntington disease     102439369 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     102439369 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     102439369 (CASP8)    05416 Viral myocarditis     102439369 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     102439369 (CASP8)    04932 Non-alcoholic fatty liver disease     102439369 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     102439369 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:mlf01002]     102439369 (CASP8) Enzymes [BR:mlf01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      102439369 (CASP8) Peptidases and inhibitors [BR:mlf01002]  Cysteine peptidases   Family C14: caspase family    102439369 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED Motif Other DBs NCBI-GeneID:  102439369 NCBI-ProteinID:  XP_023615987 LinkDB All DBs Position Unknown AA seq 504 aa AA seqDB search MDFSNCLYEIGEALSSDEVASLKFLCLDYIPLRKQEPIKDALMLFEKLQEKKMLEEDNLS FLRELLFRIDRLDLLEKRLKTSQEQMRRELQIPGRAQISAYRVMLFQISEDVTAPELKDF KFFLNRELSRCKLADSMSLLDIFMEMEKRLILGEKNLDTLKRICGQINRSLLDKISAYEK LSKESGVLCEEKXAGLLGKQCQLGWEPLNEPNLAQGPAXPWTRELFAHISSVXPQCQLLG CVFVFQTADKVYRMESKPRGYCVIFNNYDFSKAREKVPKLRKIKDRTGTDLDAEALHNTF SELHFEVVHYKDATAKTICEILKDYQRMDHNGKDCFICCILSHGDKGIVYGCDGQEAPIY ELTSYFTGLKCPSLAGKPKIFFIQACQGDNYQKGIAVETDSEEKEAYLEMDSNQKRNIPD EADFLLGMATVNNCVSYRNPTEGTWYIQSLCQSLRERCPRGDDILTILTEVNFEVSNKDD KKNMGKQMPQPTFTLRKKLYFPLN NT seq 1515 nt NT seq  +upstreamnt  +downstreamnt atggatttcagcaattgtctgtatgagattggggaagcactgagcagtgatgaggtggcc tcgctcaagttcctgtgcctggactacatcccactaaggaagcaggagcccatcaaggat gccttgatgctctttgagaaactccaggagaagaaaatgctggaggaggacaacttgtcc ttcctgagggagctgctattccgaatcgacaggctggatctgctggaaaagcgcctgaaa accagccaggagcagatgcggagggagcttcagatcccgggccgggctcagatctctgcg tacagggtcatgcttttccagatttcagaagatgtaactgcaccggaattgaaggacttt aagttttttttgaaccgggagctctccagatgtaaactggcggatagcatgagcttgctt gatatttttatggagatggagaagagacttatccttggggaaaaaaatttggacacccta aaaagaatctgtggacaaatcaaccggagcctgctggataaaatcagtgcttatgaaaaa ttaagtaaagagtctggggtcctgtgtgaggagaaatgagcaggcttgttagggaaacaa tgtcagcttgggtgggagccattgaatgagcccaatctggctcaggggccagcctaacct tggaccagggagttgtttgctcacatctcaagtgtttgaccgcagtgtcagctcctgggt tgtgtttttgtttttcagacagcagacaaagtttaccgaatggaaagcaaacctcgggga tactgtgtgatctttaataattatgattttagcaaagcacgggagaaggtgcccaaactt cgcaaaattaaggataggactggaacagacttggatgcagaggctttgcacaacaccttt agtgagcttcattttgaggtagtgcattacaaagatgccacagcaaagacaatctgtgag atcctgaaagactaccaacgcatggaccacaatggcaaagactgcttcatctgctgcatc ctttcccatggagacaagggcatcgtctatggctgcgatgggcaggaagcccccatctat gagctgacctcttacttcactggtttgaagtgcccttcccttgcaggcaaaccgaaaatc ttttttatccaagcttgccaaggggataactaccagaaaggcatagctgttgagaccgac tcagaggagaaggaagcctatttagaaatggactcgaaccagaagagaaatatcccagat gaggctgactttctgctggggatggccactgtgaacaactgtgtttcctaccgaaacccc acagaggggacctggtatatccagtcactgtgccagagtctgagagaaagatgtcctagg ggtgatgacattctcaccatcctcactgaggtaaactttgaagtgagcaataaggacgac aagaagaatatgggaaagcagatgccacaacccactttcacgctgagaaaaaaactctac ttccccctcaattga

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