Myotis lucifugus (little brown bat): 102442509 Help Entry 102442509         CDS       T07795                                  Symbol IRS1 Name (RefSeq) insulin receptor substrate 1   KO K16172   insulin receptor substrate 1 Organism mlf  Myotis lucifugus (little brown bat) Pathway mlf04022   cGMP-PKG signaling pathway mlf04068   FoxO signaling pathway mlf04081   Hormone signaling mlf04140   Autophagy - animal mlf04150   mTOR signaling pathway mlf04151   PI3K-Akt signaling pathway mlf04152   AMPK signaling pathway mlf04211   Longevity regulating pathway mlf04213   Longevity regulating pathway - multiple species mlf04722   Neurotrophin signaling pathway mlf04910   Insulin signaling pathway mlf04920   Adipocytokine signaling pathway mlf04923   Regulation of lipolysis in adipocytes mlf04930   Type II diabetes mellitus mlf04931   Insulin resistance mlf04932   Non-alcoholic fatty liver disease mlf04935   Growth hormone synthesis, secretion and action mlf04960   Aldosterone-regulated sodium reabsorption mlf05010   Alzheimer disease mlf05206   MicroRNAs in cancer mlf05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:mlf00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     102442509 (IRS1)    04022 cGMP-PKG signaling pathway     102442509 (IRS1)    04151 PI3K-Akt signaling pathway     102442509 (IRS1)    04152 AMPK signaling pathway     102442509 (IRS1)    04150 mTOR signaling pathway     102442509 (IRS1)   09133 Signaling molecules and interaction    04081 Hormone signaling     102442509 (IRS1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     102442509 (IRS1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102442509 (IRS1)    04923 Regulation of lipolysis in adipocytes     102442509 (IRS1)    04920 Adipocytokine signaling pathway     102442509 (IRS1)    04935 Growth hormone synthesis, secretion and action     102442509 (IRS1)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     102442509 (IRS1)   09156 Nervous system    04722 Neurotrophin signaling pathway     102442509 (IRS1)   09149 Aging    04211 Longevity regulating pathway     102442509 (IRS1)    04213 Longevity regulating pathway - multiple species     102442509 (IRS1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     102442509 (IRS1)   09164 Neurodegenerative disease    05010 Alzheimer disease     102442509 (IRS1)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     102442509 (IRS1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     102442509 (IRS1)    04932 Non-alcoholic fatty liver disease     102442509 (IRS1)    04931 Insulin resistance     102442509 (IRS1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IRS PH PH_11 Motif Other DBs NCBI-GeneID:  102442509 NCBI-ProteinID:  XP_006082648 Ensembl:  ENSMLUG00000000967 UniProt:  G1Q7F2 LinkDB All DBs Position Unknown AA seq 1231 aa AA seqDB search MASPTETEGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKSH HDGASAPGTGGGGGSCSGSSGVGEAGEDLSFGDSNPGPAFKEVWQVVLKPKGLGQTKNLI GIYRLCLTSKTISFVKLNTEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQV EDSVVAQSMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLT RRSRTESITATSPASLVGGKQGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHR GCSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSP SDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGASTLAAPN GHYILPRSGNGHRYLPATGLGTNSALAGDEAASAADLDNRFRKRTHSAGTSPTISHQKTP SQSSVASIEEYTEMMPACPPGGGSGGRLPGYRHSAFLPTQSYPEEGLEMHPLERRGGHSR PDTSTLHTDDGYMPMTPGVAPVPGSRKGSGDYMPMSPKSVSSPQQIINPLRRHPQRVDPN GYMMMSPSGSSSPDTGGGPSSSNSAAPSRSSYGKLWTNGVGGHHAHPLPPSKLPSESSGG KLLPCTGDYMNMSPVGDSNTSSPSDCYCGPEDPQHKSVLSYCSLPRSFKHTQRPGDLEET ARHQHLRLSSSSGRLLYAAAAEDSSSSTSNDSLGGGYCGVRPEPSLPQHLHHQVLQSHLP RKVDSAAQTNSRLARPTRLSLGDPKASTLPRAREQQQPALLLPPEPKSPGEYVNIEFGSD QPGYLSGPVASHSSPSVRCPSQLQPAPREEESGTEEYMNMDLGPGRRATWQESPVVQLSR VGPAPPGTASTCRPTRAVPSTSTRGDYMTMQMGCPHQSYVDTSPVAPVSYADIRTGIVEE ASLPGAIAAAPSSSSTASASPTAPQGAGELVAPQGSGGTSAFTRVNLSPSGNQSAKVIRA DPQGCRRRHSSETFSSMPSTPRAGNMVPSGGAAVGGSSGGSSSIEDVKRHSSASFENVWL RPGELGGAPKEQAQVCGAAGGLENGLNYIDLDLVKDFKQHPQEHPRQVQHPQPPTLRHPP GSSESSSTSRSREDVSAYASISFQKQPEDLQ NT seq 3696 nt NT seq  +upstreamnt  +downstreamnt atggcgagccctacggagaccgagggcttctcggacgtgcgcaaggtgggctacctgcgc aaacccaagagcatgcacaagcgcttcttcgtgctgcgggcggccagcgaggcggggggc ccggcgcgcctggagtactatgagaacgagaagaagtggcggcacaagtcgagcgccccc aaacgctcgatccccctcgagagctgtttcaacatcaacaagcgggctgactccaagaat aagcacctggtggccctctacacccgggacgagcactttgcgatcgcagcggacagcgag gccgagcaggacagctggtaccaggccctcctgcagctgcataaccgcgccaagagccac cacgacggggcttcggcccccgggacaggaggcggcgggggcagctgcagcggcagctct ggcgttggcgaggccggggaggacctgagcttcggggacagcaacccagggcccgccttc aaagaggtctggcaggtggtcttgaaacccaagggcctgggtcagacaaagaacctgatt ggtatctaccgcctctgcctgaccagcaagaccatcagcttcgtgaagctgaacacagag gcggccgcagtggtgctgcagctgatgaacatccggcgctgtggtcactcggagaacttc ttcttcatcgaagtgggccgttccgcagtgaccggccccggggagttctggatgcaggtg gaggactcggtggtggcccagagcatgcacgagaccatcctggaggccatgcgggcgatg agcgatgaattccggcctcgcagcaagagccagtcttcctccaactgctccaaccccatc agtgtcccgctgcgcaggcaccacctcaacaaccctccacccagccaggtggggctgacc cgccgctcacgcaccgagagcatcacggccacctctccagccagcctggtgggcggcaag cagggctccttccgtgtccgcgcctccagcgacggagaaggcaccatgtcccgcccggcc tcggtggacggcagccctgtgagtcctagcaccaacaggacccacgcccacaggcatcgg ggctgctcgcggctgcaccccccactcaaccacagccgatccatacccatgccttcttct cgctgctcgccttctgccaccagccctgtcagtctgtcgtccagcagcaccagtggccat ggctccacctctgactgtcttttcccgcggagatctagtgcttctgtgtctggctcccct agtgatggcggtttcatctcttccgatgagtatggctccagtccctgcgatttccgaagt tccttccgcagtgtcaccccagattctctgggccacaccccaccggcccgcggggaggag gagctgagcaactacatctgcatgggaggcaagggcgcctccactctcgccgcccccaat ggtcactacattttgcctcggagtggcaatggtcaccgctacctcccagccacgggcttg ggcacgaactcggccctggctggggatgaagcagccagcgctgcagatctggataatcgg tttcgcaagcggactcactcagctggcacctcccccaccatttcccaccagaagacccca tcgcagtcctccgtggcttccattgaggaatatacagagatgatgcctgcctgcccacca ggaggtggcagtggaggccgactgcccggctacaggcactccgccttcctgcccacccag tcctaccctgaggagggtctggaaatgcaccccctggagcgccgcggaggccacagccgc ccagacacctccaccctccacacggatgatggctacatgcccatgaccccaggagtggcc ccagtgcccggcagccggaaaggcagtggggactacatgcctatgagccccaagagtgtg tcttccccgcagcagatcatcaaccccctcagacgccatccccagagagtggaccccaat ggctacatgatgatgtccccaagtggcagcagctccccagatactgggggtgggcccagc agcagcaacagtgctgccccttctaggagtagctatgggaagctgtggacaaatggggtt gggggccaccacgcccaccccctgccaccctccaaactaccctcggagagcagtggtggg aagctcttgccttgtacaggtgactacatgaacatgtcaccggtgggggactccaacacc agcagcccctctgactgctactgcggccctgaggacccccagcacaagtcagttctctcc tactgctcattgccaaggtcctttaagcacacccagcgcccgggggacctggaggagacc gcccggcaccagcacctccgcctttcctccagctccggtcgccttctctatgctgcagca gccgaagattcctcctcctccaccagcaacgacagcctgggtgggggatactgtggggtg aggcccgagcccagcctcccgcaacatctccaccatcaggtcctgcagtcccatctgcct cgaaaggtggactcagctgcgcagaccaacagccgcctggctcggcccacgaggctttcc ctgggggaccccaaggccagcaccttacctcgggctcgagagcagcagcagccggcccta ctgcttcctccagagcccaagagcccaggggaatatgtgaatatcgaatttgggagtgat cagcctggctacttatctggtcccgtggcatcccacagctcgccttctgtcaggtgtcca tcccagctccagccagctcccagggaggaagagtctggcactgaagagtacatgaacatg gacctggggcctggccggagggctacctggcaggagagccctgtggtccagctgagcaga gtgggtcctgcacctccagggactgccagcacatgcaggcctacccgggcagtgcctagc actagcactcggggtgactacatgaccatgcagatgggttgtccccatcagagctacgtg gacacctctccagttgcccctgtcagctatgctgatattcggacaggcattgtggaggag gcgagccttcccggggctatagcggctgctccctcctcatcctcaacagcctctgcttcc cccactgcgcctcaaggagcaggggagctggtggccccgcaggggtccgggggcacgagt gccttcacccgggtgaacctcagtcccagtggcaaccagagtgccaaagtgatccgtgca gacccgcaagggtgccggaggcggcatagctccgagaccttctcctccatgcctagtacc ccccgggccggcaacatggtgccctcagggggggctgcagtagggggcagcagtggaggc agcagcagcattgaggatgtgaaacgtcacagctctgcttcatttgagaacgtgtggctg aggcctggggagctcgggggagcacccaaagagcaggctcaagtgtgtggggctgcaggg ggtttggagaatggtctgaactacatagacctggatttggtcaaggactttaaacagcac ccccaggagcacccccgtcaagtgcagcatccccagcccccaacccttcgtcatcctccg ggcagcagtgagagcagctctaccagccgctccagggaggatgtaagcgcctatgccagc atcagttttcagaagcagccagaggacctccagtag

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