Mycobacterium lacus: MLAC_21270
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Entry
MLAC_21270 CDS
T07377
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
mlj
Mycobacterium lacus
Pathway
mlj00270
Cysteine and methionine metabolism
mlj00450
Selenocompound metabolism
mlj00670
One carbon pool by folate
mlj01100
Metabolic pathways
mlj01110
Biosynthesis of secondary metabolites
mlj01230
Biosynthesis of amino acids
mlj04980
Cobalamin transport and metabolism
mlj04981
Folate transport and metabolism
Module
mlj_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
mlj00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
MLAC_21270 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
MLAC_21270 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
MLAC_21270 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
MLAC_21270 (metH)
04980 Cobalamin transport and metabolism
MLAC_21270 (metH)
Enzymes [BR:
mlj01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
MLAC_21270 (metH)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding_2
B12-binding
MOV-10_beta-barrel
Motif
Other DBs
NCBI-ProteinID:
BBX96833
UniProt:
A0A1X1YE00
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All DBs
Position
complement(2259188..2262766)
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AA seq
1192 aa
AA seq
DB search
MTAANEHHYDTDLLDVLSRRVVVGDGAMGTQLQGADLTLDDFRGLEGCNEILNETRPDVL
EAIHRNYFEAGADAVETNTFGCNLSNLGDYDIADKIRDLSEKGTAIARRVADEMATPDRR
RYVLGSMGPGTKLPTLGHTEYAVIRDAYTEAALGMLDGGADAILVETCQDLLQLKAAVLG
SRRAMKRAGRHIPVFAHVTVETTGTMLLGSEIGAALTAVEPLGVDMIGLNCATGPAEMSE
HLRHLSRHARIPVSVMPNAGLPVLGAKGAEYPLLPDELAEALSGFIAEFGLSLVGGCCGT
TPAHIREVAAAVADVNRPERHVTSEPSVSSLYTAIPFAQDASVLVIGERTNANGSKGFRE
AMIAEDYQKCLDIAKDQTRDGAHLLDLCVDYVGRDGVADMKALASRLATSSTLPIMLDST
ETPVLRAGLEHLGGRCAINSVNYEDGDGPESRFAKTMELVAEHGAAVVALTIDEEGQART
AEKKVEIAERLIADITGNWGVDESSILIDTLTFTIATGQEESRRDGIETIEAIRELKRRH
PNVQTTLGLSNISFGLNPAARQVLNSVFLHECQEAGLDSAIVHASKILPINRIPEEQRNV
ALDLIYDRRRDGYDPLQELMRLFEGVSAASSKESRAAELAKLPLFERLAQRIVDGERNGL
EADLDEAMTQKPPLEIINENLLAGMKTVGELFGSGQMQLPFVLQSAEVMKTAVAYLEPHM
EKAEGDAGKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNIGIKQPIANILEVAEDKS
ADVVGMSGLLVKSTVVMKENLEEMNTRGVAERFPVLLGGAALTRSYVENDLAEVYEGEVH
YARDAFEGLKLMDTIMSAKRGEAPDTDSPEAIAARKKEAERKARHERSKRIAAQRKAAEE
PVEVPERSDVAADVEVPVPPFWGSRIVKGLAVADYTGLLDERALFLGQWGLRGVRGGQGP
AYEDLVETEGRPRLRHWLDQLSTDGILAHAAVVYGYFPAVSEGDDVVVLTEPKADARERF
RFTFPRQQRGRFLCIADFIRSRELASERGEVDVLPFQLVTMGQPIADFANKLFASNSYRD
YLEVHGIGVQFTEALAEYWHRRIREELKFSGDRAMAADDPDAVEDYFKLGYRGARFAFGY
GACPDLEDRAKMMELLQPERIGVTLSEELQLHPEQSTDAFVLHHPEAKYFNV
NT seq
3579 nt
NT seq
+upstream
nt +downstream
nt
gtgactgcagcaaacgaacaccactacgacaccgatctcctcgacgttttgtcgcggcgc
gtggtggtgggcgacggcgccatgggcacccagttgcagggcgcggacctcacgctcgac
gacttccgcggcctggaaggctgcaacgagatcctcaacgagacccgccccgacgtgctg
gaagccatccaccgcaactacttcgaggcgggtgccgacgccgtcgagacgaacacgttc
ggctgcaacctgtccaacctcggcgactacgacatcgccgacaagatccgcgacctgtcg
gagaagggcaccgcgatcgcccgccgggtcgccgacgagatggccacaccggaccgcaga
cgctacgtgctggggtcgatggggccgggcaccaagctgccgacgctgggccacaccgag
tacgcggtcatccgtgacgcctacaccgaggccgccctcggcatgctcgacggcggcgcc
gacgccatcctggtggaaacctgccaggacctgctgcagctcaaggcggcggtgctgggg
tcgcgtcgcgcgatgaagcgggccgggcggcacattccggtgttcgcgcacgtcaccgtg
gagaccaccggcacgatgctgttgggcagcgagatcggcgcggcgctgacggccgtcgag
ccgctcggcgtggacatgatcggtttgaattgcgcgaccgggcccgccgagatgagcgag
cacctgcggcacctgtcgcggcacgcccgcatcccggtgtcggtgatgcccaacgccggg
ttgccggtgctgggcgcgaaaggcgctgaatatccgctgctgccagacgaattggcggag
gcgctgtccggtttcatcgccgagttcggactgtcgctggtcggcggctgttgtggtacc
accccggcccacatccgggaggtggccgccgcagtcgctgacgtcaaccgccccgagcgc
cacgtcacctccgagccgtcggtgtcgtcgctgtacaccgccatcccgttcgcgcaggac
gcctcggtcctggtgatcggcgagcggacaaatgccaacggctccaagggctttcgtgag
gcgatgatcgccgaggactaccagaagtgtctggacatcgccaaggaccagacccgcgac
ggcgcacacctgctggatctatgtgtcgactacgtgggccgcgacggcgtggccgacatg
aaggcactggccagccggctggccacgtcgtcgacgctgccgatcatgctggactccacc
gaaaccccggtgctgcgagccggtttggagcatctgggtggccgctgcgccatcaactcg
gtcaactacgaggacggcgacggcccggagtcgcgcttcgccaagaccatggagctggtc
gccgagcacggcgcggcggtggtcgcgctgaccatcgacgaagagggtcaggcccgcacc
gcggagaagaaggtcgagatcgccgagcggctgatcgccgacatcaccggcaactggggc
gtcgacgaatcctccatcctcatcgacactttgacattcaccatcgccaccgggcaggag
gagtcgcgccgcgacggcatcgagaccatcgaggcgatccgcgagctcaagcggcgtcac
cccaacgtgcagaccacgctgggcttgtccaacatctcgttcggcctcaatcccgctgcg
cgccaagtgctcaactcggtgttcttgcacgaatgccaggaggcggggctggactcggcg
atcgtgcacgcgtcgaagatcctgcccatcaaccgcatacccgaagaacaacgcaacgtc
gcgctggacctgatctacgaccgccgccgcgacggctatgacccgctgcaggagctgatg
cgcctgttcgagggcgtgtcggcggcgtcgtcaaaagaatcccgggccgccgaactggcg
aaactgcccctgttcgagcggctggcgcaacgcatcgtcgacggcgaacgcaacggcctc
gaggcagacctcgacgaggcgatgacgcagaagccgccgctggagatcatcaacgagaac
ctgttggccggcatgaagaccgtcggcgagctgttcggctccggccagatgcagctgccg
ttcgtgttgcagtccgccgaggtgatgaaaaccgcggtcgcctacctggagccgcacatg
gaaaaggccgaaggtgacgccggcaagggacggatcgtgctcgccaccgtcaagggcgac
gtgcacgacatcggcaagaacctcgtcgacatcatcttgagcaacaacggctacgaggtg
gtcaacatcggcatcaagcagccgattgccaacattctcgaggtcgccgaggacaagagc
gccgacgtggtcggcatgtcgggcctgctggtgaagtcgaccgtggtgatgaaggaaaac
ctcgaggagatgaacacccggggagtcgccgaaaggttcccggtgctgctcggcggcgcg
gcgctgacgcgcagttatgtggagaacgacctggccgaagtctacgagggcgaagtgcat
tacgcgcgagacgcttttgagggcctgaagctgatggacaccatcatgagcgccaagcgg
ggcgaggcgccggacaccgacagcccggaggcaatcgcggcccgcaagaaggaagccgag
cgcaaggcccgtcacgagcggtccaaacgcattgcggcgcaacgcaaagcggccgaagag
ccggtcgaagtgcccgaacgctccgatgtcgcggccgatgtcgaggtccccgttccgccg
ttctggggatcgcggatcgtcaagggcctagcggtggccgactacaccggcctgctcgac
gagcgagcgttgttcttgggccagtggggtttacgcggtgtgcgcggcggacagggaccg
gcgtacgaggacctcgtcgagaccgaaggccggccccggctgcggcactggctcgaccag
ttgtccaccgacggcatcctggcgcacgccgccgtggtgtacggctacttcccggcggtc
tccgagggcgacgacgtcgtggtgctcaccgagccgaaagccgatgcgcgggagcggttc
cggttcaccttcccgcgccagcaacgcggccggttcctgtgcatcgccgacttcatccgg
tcgcgagagctggccagcgagcgcggcgaggttgacgtgctgccattccaactggtgacc
atgggccaacccatcgccgacttcgccaacaagctgttcgcgtccaattcctatcgcgat
tacctcgaagtgcacgggatcggcgtgcaattcaccgaggcgcttgccgaatactggcac
cggcgtatccgcgaggagctcaagttttccggggaccgggcgatggccgctgacgatccc
gatgccgtcgaggactatttcaagctcggctaccgtggtgcccggttcgccttcggttac
ggcgcatgcccggacctcgaggaccgggccaagatgatggagctgctgcagcccgaacgc
atcggcgtgacgttgtccgaggagttgcagctgcatcccgagcagtcgaccgacgcgttc
gtcctgcaccatcccgaggccaagtacttcaacgtgtga
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