Mycobacterium lacus: MLAC_22550
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Entry
MLAC_22550 CDS
T07377
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mlj
Mycobacterium lacus
Pathway
mlj00010
Glycolysis / Gluconeogenesis
mlj00020
Citrate cycle (TCA cycle)
mlj00620
Pyruvate metabolism
mlj00785
Lipoic acid metabolism
mlj01100
Metabolic pathways
mlj01110
Biosynthesis of secondary metabolites
mlj01120
Microbial metabolism in diverse environments
mlj01200
Carbon metabolism
mlj01210
2-Oxocarboxylic acid metabolism
Module
mlj_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mlj00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MLAC_22550 (aceE)
00020 Citrate cycle (TCA cycle)
MLAC_22550 (aceE)
00620 Pyruvate metabolism
MLAC_22550 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MLAC_22550 (aceE)
Enzymes [BR:
mlj01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MLAC_22550 (aceE)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
BBX96961
UniProt:
A0A7I7NMJ6
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All DBs
Position
2399214..2402048
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AA seq
944 aa
AA seq
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MTTEFARHDLAKTPSSAREPDRVRVIREGVASYLPDIDPEETSEWLESFDELLERSGPTR
ARYLMLRLLERAGEQRIAIPALTSTDYVNTIPTELEPWFPGDADVERRYRAWIRWNAAIM
VHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKSHPGGGDQVFIQGHASPGIYARAF
LEGRLSADQLDGFRQEHSHLGGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNHY
LHDRGIKDTSDQHVWCFLGDGEMDEPESRGLAHVGALEGLDNLTFVINCNLQRLDGPVRG
NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDGDYQTYKANDG
AYVRDHFFGRDPRTKALVEHMSDSEIWNLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKT
IKGYSLGAHFQGRNATHQMKKLALEDLKYFRDAMRIPISDAQLEEDPYLPPYYHPGPDAP
EIRYLLDRRRALGGFLPERRTNAKALKLPGRDIYAPLKRGSGSQEVATTMAVVRTFKEVL
RDRQIGPRIVPIIPDEARTFGMDSWFPSLKIYNRLGQLYTAVDAELMLAYKESEIGQILH
EGINEAGSVASFTAAGTSYATHNEPMIPIYIFYSAFGFQRTGDGLWAAADQMARGFLLGA
TAGRTTLTGEGLQHADGHSLLLAATNPAVVSYDPAFAYEIAYIVESGLSRMFGENPENVF
FYITVYNEPYVQPPEPENFDPEGLLRGMYRYRAATEQHTSRAQILASGVSMPAALKAAEL
LAAEWDVAADVWSVTSWGELNRDGVAAETANLRHPERPARVPYVTQALAGCSGPVIAVSD
WMRAVPEQIRPWVPGSYVTLGTDGFGFSDTRPAARRYFNTDAESQAVAVLEALARDGEID
QSVPVTAAKQYRIDDVQAAPELGVLPSSAVTPPACGGTSDPGVA
NT seq
2835 nt
NT seq
+upstream
nt +downstream
nt
ttgaccaccgagttcgcgcgccacgatctggccaaaaccccaagcagcgcaagggaaccc
gaccgcgttcgggtgatccgcgagggtgtggcgtcctacctgcccgatatcgatcccgag
gagacgtcggagtggctcgagtccttcgacgaattgctggagcggtcgggcccgacgcgg
gcgcgctacctgatgctgcggcttctggaacgcgccggcgagcagcggatcgccatcccg
gcgttgacctcgaccgattacgtcaacaccatcccgaccgaactggagccgtggtttccc
ggcgacgcagacgtcgaacgccgataccgggcctggatccgatggaacgcggcgatcatg
gtgcaccgcgcgcaaagaccgggcgtgggcgtcggtggtcacatttcgacctacgcgtcg
tcggctgcgctctacgaggtcggtttcaaccacttcttccggggcaaatcgcaccccggc
ggcggggaccaggtgttcatccagggccacgcgtcccccggcatttatgcgcgcgccttc
ctggaaggccgcctgtccgcggaccagcttgacggcttccgccaggagcacagccatctc
ggcggcgggttgccgtcctacccgcacccgaggctgatgcccgacttctgggaattcccc
acggtgtcaatggggctgggcccgatgaacgccatctaccaggcccggttcaaccattat
ctgcacgaccgcggtatcaaagacacctccgaccagcacgtgtggtgtttcttgggcgac
ggcgagatggatgagccggagagccgcggcctggcccatgtgggcgccctggaaggcctg
gacaacctgacgttcgtgatcaactgcaacctgcagcgcctcgacggcccggtccgcggc
aacggcaagatcatccaggagttggagtcgttcttccgcggggccggctggaacgtcatc
aaggtggtgtggggccgtgaatgggacgccctgctgcacgccgaccgcgacggcgccttg
gtgaacttgatgaacacgacgcccgatggtgattaccagacctacaaggccaacgacggc
gcctacgtgcgcgaccacttctttgggcgcgacccacgcaccaaggctctcgtggagcac
atgagcgactccgagatctggaacctcaagcgtggcgggcacgactatcgcaaggtctac
gccgcctaccgggccgccgtcgaccacaagggacagccgacggtgattctggccaagacc
atcaagggctactcgctgggcgcgcacttccagggccgcaacgccacccatcagatgaaa
aagcttgcgctggaagacctcaagtacttccgggacgccatgcgcattccgatcagcgac
gctcaattggaggaggatccgtacctgccgccgtactaccaccccgggccggacgccccg
gagatccggtacctgctcgatcggcgccgcgcgctggggggctttctgcccgagcgccgc
actaacgccaaggcgctgaagcttcctggccgcgacatctacgccccgttgaagaggggc
tcgggaagccaggaggtcgccaccaccatggcggtggtgcgcaccttcaaggaagtattg
cgggacaggcaaattggcccgcggatcgtgccgatcattcccgacgaggcgcgcacgttc
gggatggactcgtggttcccgtcgttgaagatctacaaccgccttggtcagctgtacacg
gcggtcgacgccgagctgatgctggcgtacaaggagagcgagatcgggcagatcctgcac
gagggcatcaacgaagccgggtcggtggcctcattcaccgcggccggcacctcgtatgcg
acgcacaacgaaccgatgatcccgatctacatcttctattcggcgttcgggttccagcgc
accggcgacggcctgtgggccgcggccgaccagatggcgcgtggcttcctgctcggcgcc
accgcgggacgcaccacactgaccggcgagggcctgcagcacgccgacggtcactcgcta
ctgttggcggccaccaacccggcggtggtctcctacgaccccgcgttcgcctacgaaatc
gcctacatcgtggaaagcgggctgtcccggatgttcggggagaacccggagaacgtgttc
ttctacatcaccgtctacaacgagccgtatgttcagccgccggagccggagaacttcgat
cccgagggcctgctgcggggcatgtaccggtaccgggccgccacggagcagcacaccagc
agggcgcagatcctggcctcgggggtgtccatgcccgccgcgctgaaggcggcggagctg
ctggccgccgagtgggatgtcgccgccgacgtgtggtcggtgaccagttggggcgagctc
aaccgcgacggggttgccgccgagaccgccaacctgcgccaccccgaacgaccggcccgc
gtcccgtacgtgacccaggccctcgccgggtgcagcgggcccgtgatcgccgtatccgat
tggatgcgcgcggtccccgagcagatccggccctgggtgcccggctcctacgtcacgctg
ggcaccgacgggttcggcttctccgacacccggcccgccgctcggcgctacttcaacacc
gacgccgaatcccaggcggtcgcggtgctggaggcgctggcacgcgatggtgagatcgac
caatcggtgccagtcacggccgccaagcagtaccggatcgacgacgtgcaggccgcgccg
gagctgggggtactccccagctccgcggtgaccccacccgcttgcgggggaacgtcggat
cccggcgtcgcgtga
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