Mustela lutreola (European mink): 131807816
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Entry
131807816 CDS
T09578
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
mlk
Mustela lutreola (European mink)
Pathway
mlk04120
Ubiquitin mediated proteolysis
mlk04144
Endocytosis
mlk04330
Notch signaling pathway
mlk04668
TNF signaling pathway
mlk04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
mlk00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
131807816 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
131807816 (ITCH)
04668 TNF signaling pathway
131807816 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
131807816 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
131807816 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mlk04131
]
131807816 (ITCH)
04121 Ubiquitin system [BR:
mlk04121
]
131807816 (ITCH)
Enzymes [BR:
mlk01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
131807816 (ITCH)
Membrane trafficking [BR:
mlk04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
131807816 (ITCH)
Ubiquitin system [BR:
mlk04121
]
Ubiquitin ligases (E3)
HECT type E3
131807816 (ITCH)
BRITE hierarchy
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
131807816
NCBI-ProteinID:
XP_058989454
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Position
9:complement(23923622..24060428)
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AA seq
880 aa
AA seq
DB search
MYCWILLASILICRPIGGMSGSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPY
VEVTVDGQSKKTEKCNNTNSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDI
FETLKSNNMKLEEVVVTLQLVGDKEPTETIGDLSVCLDGLQLDSEVVTNGETTCSESASQ
SDDGSRPKDETRTNTNGSDEPEDAGAGENRKVNGNNSPSLSNGGFKPSRPPRPSRPPPPT
PRRPASVNGSPSATSESDGSSTGSLPPTNINSNTSEGATSGLIIPLTISGGSGPRPLNPV
PQAPLPPGWEQRVDQHGRVYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRT
TTWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIYGNQDLFTTSQNKEFDPLGPLPPG
WEKRTDSNGRVYFVNHNTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRT
TTYIDPRTGKSALDNGPQIAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQ
QIMSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQ
INPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPE
FYNSLIWVKENNIEECGLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAE
WRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYT
RTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKEN
WLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE
NT seq
2643 nt
NT seq
+upstream
nt +downstream
nt
atgtactgttggatcctattggctagtattttgatttgccgtcctattggtggtatgtct
ggcagtggatcacagcttggttcaatgggtagcctgaccatgaaatcacaacttcagatc
actgtcatttcagcaaaacttaaagaaaataaaaagaattggtttggaccaagtccttat
gtggaagtcacagtagatggacagtcaaagaagacagaaaaatgcaacaatacgaacagt
cccaaatggaagcaaccccttacagttatcgtcacccctgtgagtaaattacattttcgt
gtatggagtcaccagacactgaaatctgatgttttgttgggaactgctgcattagatatc
tttgaaaccttaaagtcaaacaacatgaaacttgaggaagtagttgtgactttacagctt
gtaggtgacaaagagccgacagagacaataggagacttgtcagtttgtcttgatgggctg
cagttagattctgaagttgttaccaatggtgaaactacatgttcagaaagtgcttcacag
agtgatgatggctccagacccaaggatgaaacaagaacaaacacaaatggatcagatgag
cctgaggatgcaggggctggtgaaaataggaaggtcaatgggaataattctccatcactc
tcaaatggtggttttaaaccttctaggcctccaagaccttcacgaccacctccacctacc
ccacgtagaccagcatctgtcaatggttccccatctgccacttctgaaagtgatggatcc
agtacaggctctctgccaccaacaaatataaattcaaatacatctgaaggagcaacatct
ggattaataattcctctgactatatctggaggctcaggccctcggccattaaatcctgta
cctcaggctcccctaccacctggttgggagcagagagtggaccagcatgggcgagtttac
tatgtagatcatattgaaaaaagaacaacatgggatagaccagaacctctacctcctggc
tgggaacgtcgggttgacaacatgggacgaatttactatgttgaccatttcacaagaaca
acaacgtggcagaggccaacattggaatccgtccggaactatgaacagtggcagctccaa
cgtagtcagctgcaaggagcaatgcagcagtttaaccagagatttatttatgggaatcaa
gatttgtttactacatcacaaaataaagaatttgatccccttggtcccctgccacctgga
tgggagaagagaacagacagcaatggtagagtatattttgtcaaccacaacactcgtatc
acacagtgggaagatcccagaagtcaaggtcaattaaatgaaaagcccttgcctgaaggc
tgggaaatgagattcacagtcgatggaattccgtattttgtggaccacaatagaagaaca
accacctatattgatccccgcactggaaaatctgccctagacaatggaccacagatagcc
tatgtacgggatttcaaggcaaaagttcagtatttccggttctggtgtcagcaactggcc
atgccacagcacataaagattacagtgacaagaaagaccttgtttgaagattcctttcag
cagataatgagcttcagtccccaagatctgcgaagacgtttgtgggtgatttttccagga
gaagaaggtttagattatggaggtgtagcaagagagtggttctttcttttgtcacacgaa
gtgttgaacccaatgtattgcctgtttgaatatgcagggaaggacaactactgcttgcag
attaatcctgcttcttacatcaatccagatcacctgaaatactttcgttttattggcagg
tttattgccatggctctcttccatgggaaattcatagacacaggtttttctttgccattc
tataaacgtatattgaacaaaccagttggactcaaggatttagaatctattgatccagaa
ttttacaattctctcatctgggttaaagaaaataatattgaggaatgtggtttggaaatg
tacttctctgtcgataaagaaattttaggtgaaatcaagagtcatgatttgaaacctaat
ggtggcaatattcttgtgacagaagaaaataaagaggaatatatcagaatggtagctgaa
tggaggttgtctcgaggtgttgaagaacagacacaagctttctttgagggctttaatgaa
attcttccccagcagtatttgcaatactttgatgcaaaggaattagaggtccttttatgt
ggaatgcaagaaattgacttgaatgactggcaaagacatgccatctaccgccattacact
aggacaagcaaacaaatcatgtggttttggcagtttgttaaagaaattgataatgagaag
agaatgagacttctgcagtttgttactggaacctgccgattgccagttggaggatttgct
gacctcatggggagtaatggaccacaaaaattctgcattgaaaaagttgggaaagaaaat
tggttacccagaagtcatacgtgttttaatcgcctggacctgccaccctacaagagctat
gagcaactgaaggaaaagctgttatttgccattgaagaaacagaaggatttggacaagag
taa
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