Mustela lutreola (European mink): 131809629 Help Entry 131809629         CDS       T09578                                  Symbol LCK Name (RefSeq) tyrosine-protein kinase Lck   KO K05856   lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2] Organism mlk  Mustela lutreola (European mink) Pathway mlk04064   NF-kappa B signaling pathway mlk04380   Osteoclast differentiation mlk04650   Natural killer cell mediated cytotoxicity mlk04658   Th1 and Th2 cell differentiation mlk04659   Th17 cell differentiation mlk04660   T cell receptor signaling pathway mlk05135   Yersinia infection mlk05166   Human T-cell leukemia virus 1 infection mlk05235   PD-L1 expression and PD-1 checkpoint pathway in cancer mlk05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:mlk00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     131809629 (LCK)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     131809629 (LCK)    04660 T cell receptor signaling pathway     131809629 (LCK)    04658 Th1 and Th2 cell differentiation     131809629 (LCK)    04659 Th17 cell differentiation     131809629 (LCK)   09158 Development and regeneration    04380 Osteoclast differentiation     131809629 (LCK)  09160 Human Diseases   09161 Cancer: overview    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     131809629 (LCK)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     131809629 (LCK)   09171 Infectious disease: bacterial    05135 Yersinia infection     131809629 (LCK)   09163 Immune disease    05340 Primary immunodeficiency     131809629 (LCK)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mlk01001]     131809629 (LCK)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:mlk03036]     131809629 (LCK) Enzymes [BR:mlk01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      131809629 (LCK) Protein kinases [BR:mlk01001]  Non-receptor tyrosine kinases   SRC family    131809629 (LCK) Chromosome and associated proteins [BR:mlk03036]  Eukaryotic type   Centrosome formation proteins    Kinases and associated factors     131809629 (LCK) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 SH2_1 ABC1 Haspin_kinase SH3_16 SH3_3 Motif Other DBs NCBI-GeneID:  131809629 NCBI-ProteinID:  XP_058992850 LinkDB All DBs Position 10:23986332..24008252 Genome browser AA seq 509 aa AA seqDB search MGCSCSSNSEEDWMENIDVCENCHYPIVPLDGKATLPIRNGSEVRDPLVIYEGSNPPASP LQDNLVIALHSYEPSHDGDLGFEKGEQLRILERNGEWWKAQSLTTGQEGFIPFNFVAKAN SLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKH YKIRNLDQGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQKPWWEDEWEV PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL VRLYAVVTQEPIYIITEYMENGSLVDFLKTPPGIKLTINKLLDMAAQIAEGMAFIEERNY IHRDLRAANILVSDTLSCKIADFGLARLIVDNEYTAREGAKFPIKWTAPEAINYGTFTIK SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYHLMMLCWKER PEDRPTFDYLRSVLEDFFTATEGQYQPQP NT seq 1530 nt NT seq  +upstreamnt  +downstreamnt atgggctgtagctgcagctcaaactctgaagaagactggatggaaaacatcgatgtatgt gagaactgccattaccccatagtcccactggatggcaaggccacgctgcccatccgcaat ggctctgaggtgcgggatccactggtcatctatgaaggctccaaccccccagcctcacca ttgcaagacaacctggttatcgctctgcacagctacgagccctctcacgatggagacttg ggcttcgagaagggtgaacagctccgtatcctggagcggaacggcgaatggtggaaggca cagtccctgaccaccggccaggaaggtttcattcccttcaacttcgtggccaaagcgaac agcctggagcccgaaccctggttcttcaagaacctgagccgcaaggacgctgagcggcag ctcctggcgcccgggaacacgcacggctccttcctgatccgggagagcgagagcaccgcc ggatcgttttcactgtccgtgcgggacttcgaccagaaccagggagaggtggtgaaacat tacaaaatccgtaacctggaccaaggcggcttctacatctcgccccgcatcacttttcct ggcctgcacgagctggtccgccattacaccaatgcttcggacgggctgtgcacgcggttg agtcgcccctgccagacccagaagccccagaagccttggtgggaggacgagtgggaggtt cccagggagacgctgaagctggtggagcggctgggggctggccagttcggggaagtgtgg atggggtactacaacgggcacacaaaggtggcagtcaagagcctgaagcagggaagcatg tcccccgacgccttcctggccgaggccaacctcatgaagcagctgcaacaccagagactg gtccggctctacgcggtggtcacccaggagcccatctacatcatcacggaatacatggag aacgggagcctggtagatttcctcaagacccccccaggcatcaagctgaccatcaacaaa ctcctggacatggcagcccaaattgcagagggcatggcattcattgaagagcggaattat atccaccgtgacctgagggctgccaacatcctcgtttctgacaccctgagctgcaagatt gcagactttggcctagcacgcctcattgtggacaatgagtacacagccagggagggagcc aagtttcccattaagtggacagcaccggaagccattaactatgggacattcaccatcaag tcggatgtgtggtcttttgggatcctgctgacggagattgtcacccatggccgcattcct tacccagggatgaccaatcctgaggtgattcagaacctagagcgaggctaccgtatggtg cgacctgacaactgtcccgaggagctgtaccacctcatgatgctttgctggaaggagcgc ccagaggaccggcccacctttgactacctgcgcagtgtgctggaggacttcttcacggcc acagagggccagtaccagcctcagccctga

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