Mustela lutreola (European mink): 131816810
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Entry
131816810 CDS
T09578
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein isoform X1
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
mlk
Mustela lutreola (European mink)
Pathway
mlk01524
Platinum drug resistance
mlk03440
Homologous recombination
mlk03460
Fanconi anemia pathway
mlk04120
Ubiquitin mediated proteolysis
mlk04151
PI3K-Akt signaling pathway
mlk05206
MicroRNAs in cancer
mlk05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
mlk00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
131816810 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
131816810 (BRCA1)
03460 Fanconi anemia pathway
131816810 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
131816810 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
131816810 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
131816810 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
131816810 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
mlk01009
]
131816810 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
mlk04121
]
131816810 (BRCA1)
03036 Chromosome and associated proteins [BR:
mlk03036
]
131816810 (BRCA1)
03400 DNA repair and recombination proteins [BR:
mlk03400
]
131816810 (BRCA1)
Enzymes [BR:
mlk01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
131816810 (BRCA1)
Protein phosphatases and associated proteins [BR:
mlk01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
131816810 (BRCA1)
Ubiquitin system [BR:
mlk04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
131816810 (BRCA1)
Multi subunit type E3
BRCC complex
131816810 (BRCA1)
Chromosome and associated proteins [BR:
mlk03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
131816810 (BRCA1)
DNA repair and recombination proteins [BR:
mlk03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
131816810 (BRCA1)
BRCA1-A complex
131816810 (BRCA1)
BRCA1-B complex
131816810 (BRCA1)
BRCA1-C complex
131816810 (BRCA1)
BRCA complex
131816810 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
131816810 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-C3HC4
zf-C3HC4_2
zf-RING_UBOX
zf-C3HC4_4
zf-C3HC4_3
zf-RING_2
zf-RING_5
RING_XB3-XBAT31
BRCT_2
zf-Nse
zf-RING_6
zf-ANAPC11
zf-RING_10
zf-rbx1
Baculo_IE-1
Motif
Other DBs
NCBI-GeneID:
131816810
NCBI-ProteinID:
XP_059005797
LinkDB
All DBs
Position
15:19321640..19388889
Genome browser
AA seq
1879 aa
AA seq
DB search
MPQNSLEQEEMDLPADRVEEVQNVLNAMQKILECPICLELIKEPVSTKCDHIFCKFCMLK
LLNQRKGPSKCPLCKNDITKRSLQESTRFSQLVEELLKIIHAFELDTGLQFANSYNFSKK
ENNSPEHLKEEVSIIQSMGYRNRAKRLRQNEPENPTLQETSLSVQLSDLGILRSLRTKQQ
IQPQNKSVYIELGSDSSEDTVNKASYCSVRDDELLQITPQGSRAEASLNPAKKAACEISE
DITNSERHQSDNKDLTTTEKHATEKHPEKYQGISVSDLHVEPCGTNTHASSLQHENSSLL
LTKDRMNVEKAEFRNKSKQPALARSQQSRWAESKETCNDRQTPSTERKVLLKADTLCGRR
EPKKQKPLRSDSPRDSQDVPWITLNSSIQKVNEWFSRSDEMSTSDDDSHDGGSESKTEVA
GAVEVPNEVHVCSGSSEKIDLMASEPQDALIRERERVHTKSVESNIEDKIFGKTYRRKAS
LLNVSHTSEDLLIGVCAVEPQTVQAHPLTSKAKRKRRTTAGLHPEDFIKKVDLTIVPKTP
EKLVEGTDQLERSGHVTKIRNNGPEDEIKDDYVQTEKNANPTESLEKESAFRSRAEPISS
SITKMELELNSSGSKALKKNRLRRKSSTRHGCALEFVVSRNPSPPDRSELQVDSCSSSEE
MKKEPADQMPVRRSKTLQLLEEEEPAAGPKKGRKPGEQIHKRLASHAFPELSLTNVPGGF
ANCSSSNKPQETVHPSLRREDIEESRRTTQVSGSTRDPKELLLSGGRGLQIERSVENTSV
SLVPDTDCGTQDSISLLEADTVRKAKTAPNQRASLCTVIEHPKETIHSCSKDTKNGPEGF
VDPLTCEDNHTQETSIEMEESELDTQYLRNTFKVSNRQSFALFSNPRDPENDCAMVYAHS
GALRKQSPKVTPECGQKENLGRQESEIKHAQAVPAMAGFSAVIQEAQKPEDYAKCSLKGG
SNLCQSSQFRGKETELLIANNCGFSQNPYHIPPLPPIRSGIKTLCNKNPSEERFEQHSMS
PERAVGNESVIQSTVSTISQNNIRESSLREVSSSSVNEVGSSTNEVGSSTNEVGSSGENM
QAELGRNRGPQLNAMLRLGLMQPEVCNQNCKDPEMKSQGENEGIVLSVNADFSPCLISDN
PEQPMGSSHASQVCSETPDDLLNGDKIKGKISFAESDVKERSAVFSKNVQKGEFRKSPSP
LDDTLLAQGQKRRARKLESSEENTSSEEEELPCFQHLLFGKVANTPSQATSHNAVAAEGP
SKKTEENLDSQKSSLSDLSNQVPSAKASQEHHLSEETRCSGSLFSSQCSALEDMTVNTNT
QDPFLMFDAPSEQVRHQSENLDALSDKELVSDDDERELGLEEDNHEEQSVDSDLGEVASG
YQSETSFSEDCSRLSSQSDILTTQQRDTMQDNLIKLQQEMAELEAVLEQHGSQPSRSSPS
PVAGSCAPEDLLDPEQNTSEKAVLTSEKSSDYPKSQNPESLSADKYQVSLDSSTGKNKEP
GTRRSSPSQSRLLDTRWYVHSCPRSLQDTDCPSQKELIKVVSVEEQQASRSEARDFMEQP
YLPRPDLEGTPYLESGISLFSDDPESDASTDRAPEPAHVSRMPAATSALKLPQFQVEESA
KSTAAVHIANTAGYNKREDSVGREKPEVISSIKRVNRRISMVASGLTPKECMLVHKFARK
HHITLTNQISEETTHVIMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLDE
HDFEVRGDVVNGRNHQGPKRARESRDRKIFRGLEVCCYGPFTNMPTDQLEWMLRLCGASV
VKEPSLFPLSKGAHPVVVVQPDAWAEDSGFHAIGQMCEAPVVTREWVLDSVALYQRQELD
TYLIPQIPRAVAHSSQPCV
NT seq
5640 nt
NT seq
+upstream
nt +downstream
nt
atgcctcaaaattcactggaacaggaagaaatggatttacctgcggatcgtgttgaagaa
gtacaaaatgtccttaatgctatgcagaaaatcttagagtgtccaatctgtctggagttg
atcaaagagcctgtttccacaaagtgtgatcacatattttgcaaattttgtatgctgaaa
cttctcaaccagaggaaaggaccttccaagtgtcctttgtgtaagaatgatataaccaaa
agaagcctacaagaaagtacaagatttagtcaactagttgaagagctgttgaaaatcatt
catgcttttgagcttgacactggattgcagtttgcaaacagctataacttttcaaaaaaa
gaaaataactctcctgagcacctaaaggaggaagtttctattatccaaagtatgggctat
cgaaaccgtgccaaaagacttcgacagaatgaacctgaaaaccccaccttgcaggaaacc
agtcttagtgtccaactctctgaccttggaattctgagatctctgaggacaaagcagcag
atacagcctcagaataagtctgtctacattgaattgggatctgattcttctgaagataca
gttaataaggcaagttactgcagtgtgagagatgatgagttgttacaaatcacccctcaa
ggatccagggctgaagccagtttgaatcctgcaaaaaaggctgcttgtgaaatttctgag
gacataacgaatagtgaacgccatcaatccgataataaagatttgaccaccactgagaag
catgcaactgagaagcatccagaaaagtatcagggtatttctgtttcagacttgcatgtg
gagccatgtggcacaaatactcatgccagctcattacagcatgagaacagcagtttatta
ctcactaaagacagaatgaatgtagaaaaggctgaattccgtaataaaagcaaacagcct
gccttagcaaggagccaacagagcagatgggctgaaagtaaggaaacatgtaatgatagg
cagactcccagcacagagagaaaggtacttctgaaagccgataccctgtgtgggagaaga
gaaccgaagaagcagaaacctctacgctctgacagtcctagagattcccaagatgttcct
tggataacactgaatagtagcatacaaaaagtgaatgagtggttttccagaagcgatgaa
atgtcaacttccgatgatgactcacatgacgggggatctgaatcgaagaccgaagtagcc
ggtgcagtagaagttccaaacgaagtgcacgtatgttccggttcctctgagaaaatagac
ttaatggccagcgagcctcaggatgctctgatacgtgaacgcgaaagagtccacaccaag
tccgtagagagtaacatcgaagataaaatatttgggaaaacctaccggaggaaggcaagc
ctccttaacgtgagccacacgagcgaagatctgcttataggagtgtgtgctgtagaacct
cagacagtgcaagcccatcccctcacgagtaaagcaaagcgtaaaaggagaactacagca
ggccttcatcctgaggattttatcaagaaagtagatctgaccatcgttccaaagactcct
gaaaagctagttgagggaaccgaccaactcgagcgaagtggtcacgtgacgaagattaga
aataatggtcccgaggatgaaataaaagatgattatgttcagaccgagaaaaatgctaac
ccaacagaatccctggaaaaagaatctgctttcagaagcagagctgaaccgataagcagc
agtataaccaagatggaactggaattaaatagctccggttcgaaagcccttaagaagaac
aggctgcggaggaagtcctccaccaggcacggctgtgcgcttgaattcgtagtcagtcga
aatccaagcccgcctgatcgcagtgaactgcaggtcgatagctgttctagcagtgaggag
atgaagaaagaacctgcggaccagatgccagtcagacgcagcaaaacgcttcagctcctg
gaagaggaagaacctgcagctggacccaagaagggcaggaagccaggtgaacagatacat
aagagacttgccagtcatgcttttccagagctgagtttaacaaacgtaccagggggcttt
gctaactgttcgagttctaataaacctcaagagactgtccaccctagcctccgaagagaa
gacatagaagagagccgaagaacgactcaagtgtctggtagtaccagagatcccaaagag
ctgctactgagtggaggaagaggtttgcaaattgaaagatctgtagagaataccagtgtt
tccttggtacctgatacggattgtggcactcaggacagtatctcgttgctggaagccgac
accgtaaggaaggcaaaaactgcaccaaatcaacgtgcgagtctgtgcacagtaattgaa
caccccaaggaaactatccacagttgttctaaagatactaagaacggcccagaaggcttt
gtggatccactgacgtgcgaagataaccacactcaggagacaagcatagaaatggaagag
agtgaacttgatacacagtatttacgcaacacgttcaaggtttcaaaccgtcagtcattt
gctctgttttcaaatccaagagatccagaaaacgactgtgcaatggtctatgcccactct
ggggccttaaggaaacaaagtccaaaagtcactcctgaatgtggacaaaaagagaatctg
ggaaggcaagagtctgaaatcaagcatgcgcaggcagttcctgcgatggcgggcttttct
gcagttattcaggaagctcagaagccagaagattatgccaaatgtagcctcaaaggaggc
tctaacctttgtcagtcatctcagttcagaggcaaggaaactgaactccttattgcaaat
aactgtggattttcccaaaatccttatcatataccaccacttcctcccatcagatcaggt
attaaaactctttgtaacaaaaacccgtcagaagaaaggtttgagcagcattcaatgtca
ccagaaagagcagtgggaaatgagagcgtcattcagagtacagtgagcacaattagccaa
aataacatcagagaaagctcgttgagagaagtcagctccagcagtgttaatgaagtaggt
tccagtacaaacgaagtaggctctagtactaatgaagtaggttccagtggagaaaacatg
caggcagaactaggtagaaaccggggacctcaattaaatgctatgctcaggttaggtctt
atgcaacctgaagtctgtaaccaaaattgtaaagatccggaaatgaaaagtcaaggagaa
aatgaaggtatagttctgtctgttaatgcagatttctccccatgtctaatttcggataac
cccgaacaacctatgggaagtagtcatgcttctcaggtttgttcggagacacccgatgac
ctgttaaatggtgacaaaataaaggggaaaatcagctttgctgaaagtgacgttaaagaa
agatctgctgtctttagcaaaaatgtccagaaaggagaattcagaaagagccctagccct
ttagacgatacacttttggcccaagggcagaaaagaagggccaggaaattagagtcctca
gaagagaacacgtctagtgaggaggaagagcttccctgcttccaacacttactatttggc
aaagtagccaacacaccttctcaggctaccagtcacaatgctgttgctgcagagggtccg
tctaaaaaaacagaggagaacctagactcacagaagagtagtttaagtgacctcagtaac
caggtaccatcagcaaaggcatcccaggaacatcacctgagtgaggaaacgaggtgttct
ggtagcttattctcttcacagtgcagtgctttggaagacatgaccgttaatacaaatacc
caggatcctttcttgatgtttgatgctccttccgaacaagtgaggcatcagtctgaaaac
ctggatgctctgagtgacaaggaattggtttcagatgatgatgaaagggaacttggtctg
gaagaagataatcacgaagaacagagtgtggattcggacttaggtgaagtggcatccggg
taccagagtgaaacaagcttctctgaagactgttcgaggttgtcctctcagagtgatatt
ttaaccacacagcagagggataccatgcaagataacctgataaagctacagcaggaaatg
gccgaactggaagctgtgttagagcagcacgggagccagccttctcgaagttccccttcc
cccgtggcaggttcttgtgccccggaggacctgctcgatccagagcaaaacacatcagaa
aaagcagtattaacttcagagaaaagtagcgactatcctaaaagccagaatcccgaaagc
ctttctgcggacaaatatcaggtatctctggatagttccaccggtaaaaataaagaacca
ggaacaagaaggtcttccccctctcagtcccggttgttagatacgaggtggtatgtgcac
agctgcccaaggagtcttcaggacacggactgcccttcacaaaaggagctcattaaggtt
gtcagtgtagaggagcaacaagcgagtaggtcagaggcgcgagatttcatggagcagcct
tatttgccaagaccagatctggagggaaccccttacctcgagtctggaattagcctcttc
tctgatgaccctgagtctgacgcctctacagacagagccccagagccagctcatgttagc
cgcatgccagctgcaacctctgcattgaaattaccccaatttcaagttgaagaatcagcc
aagagtacagctgctgtccatattgctaatactgctgggtacaataagagggaagacagt
gtgggcagggagaagccagaagttatatcttcaataaaaagagtcaacagaagaatatct
atggtggcatcaggcttaaccccaaaagaatgtatgcttgtgcacaagtttgccagaaaa
caccacatcactttaactaatcaaatttccgaagagactactcatgtcatcatgaaaaca
gatgctgagtttgtgtgcgaacggacactgaaatattttctgggtattgcaggaggaaaa
tgggtagttagctatttctgggtgacccagtcaattaaagaaaggaagatgctagatgag
catgattttgaagttagaggagacgttgtgaatggaagaaaccaccagggtccaaagaga
gcaagagaatcccgggacaggaagatcttcaggggcctagaagtctgttgctatgggccc
tttaccaacatgcctacagatcaactcgagtggatgctgcgcctctgtggggcttctgtg
gtgaaggagccctcattattccctctcagcaagggtgcacaccctgtggtagtcgtgcag
ccagacgcctgggcagaggacagtggcttccatgcgattgggcagatgtgtgaagcacct
gtggtgactcgagaatgggttttggacagtgtagccctctaccaacgtcaggaactggac
acctacctgatcccgcagatccccagagccgtcgctcactccagccagccgtgtgtgtag
DBGET
integrated database retrieval system
