Mustela lutreola (European mink): 131827572 Help Entry 131827572         CDS       T09578                                  Symbol CASP8 Name (RefSeq) caspase-8 isoform X1   KO K04398   caspase 8 [EC:3.4.22.61] Organism mlk  Mustela lutreola (European mink) Pathway mlk01524   Platinum drug resistance mlk04115   p53 signaling pathway mlk04210   Apoptosis mlk04215   Apoptosis - multiple species mlk04217   Necroptosis mlk04620   Toll-like receptor signaling pathway mlk04621   NOD-like receptor signaling pathway mlk04622   RIG-I-like receptor signaling pathway mlk04623   Cytosolic DNA-sensing pathway mlk04625   C-type lectin receptor signaling pathway mlk04657   IL-17 signaling pathway mlk04668   TNF signaling pathway mlk04932   Non-alcoholic fatty liver disease mlk04936   Alcoholic liver disease mlk05010   Alzheimer disease mlk05016   Huntington disease mlk05022   Pathways of neurodegeneration - multiple diseases mlk05132   Salmonella infection mlk05134   Legionellosis mlk05142   Chagas disease mlk05145   Toxoplasmosis mlk05152   Tuberculosis mlk05160   Hepatitis C mlk05161   Hepatitis B mlk05162   Measles mlk05163   Human cytomegalovirus infection mlk05164   Influenza A mlk05165   Human papillomavirus infection mlk05167   Kaposi sarcoma-associated herpesvirus infection mlk05168   Herpes simplex virus 1 infection mlk05169   Epstein-Barr virus infection mlk05170   Human immunodeficiency virus 1 infection mlk05200   Pathways in cancer mlk05203   Viral carcinogenesis mlk05416   Viral myocarditis mlk05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mlk00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     131827572 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     131827572 (CASP8)    04215 Apoptosis - multiple species     131827572 (CASP8)    04217 Necroptosis     131827572 (CASP8)    04115 p53 signaling pathway     131827572 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     131827572 (CASP8)    04621 NOD-like receptor signaling pathway     131827572 (CASP8)    04622 RIG-I-like receptor signaling pathway     131827572 (CASP8)    04623 Cytosolic DNA-sensing pathway     131827572 (CASP8)    04625 C-type lectin receptor signaling pathway     131827572 (CASP8)    04657 IL-17 signaling pathway     131827572 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     131827572 (CASP8)    05203 Viral carcinogenesis     131827572 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     131827572 (CASP8)    05161 Hepatitis B     131827572 (CASP8)    05160 Hepatitis C     131827572 (CASP8)    05164 Influenza A     131827572 (CASP8)    05162 Measles     131827572 (CASP8)    05168 Herpes simplex virus 1 infection     131827572 (CASP8)    05163 Human cytomegalovirus infection     131827572 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     131827572 (CASP8)    05169 Epstein-Barr virus infection     131827572 (CASP8)    05165 Human papillomavirus infection     131827572 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     131827572 (CASP8)    05134 Legionellosis     131827572 (CASP8)    05152 Tuberculosis     131827572 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     131827572 (CASP8)    05142 Chagas disease     131827572 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     131827572 (CASP8)    05016 Huntington disease     131827572 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     131827572 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     131827572 (CASP8)    05416 Viral myocarditis     131827572 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     131827572 (CASP8)    04932 Non-alcoholic fatty liver disease     131827572 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     131827572 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:mlk01002]     131827572 (CASP8) Enzymes [BR:mlk01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      131827572 (CASP8) Peptidases and inhibitors [BR:mlk01002]  Cysteine peptidases   Family C14: caspase family    131827572 (CASP8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 DED PYRIN COG3_C Motif Other DBs NCBI-GeneID:  131827572 NCBI-ProteinID:  XP_059024401 LinkDB All DBs Position 3:complement(198232245..198255814) Genome browser AA seq 485 aa AA seqDB search MNFSKCLYNIGEQLDSDELASLKFLSMDYIPQKKQEPIKDPLMLFQRLQEKRLLEENNLS FLKELLFRINRLDLLVTYLDTSKQEMEQELQIPGRAQISAYRVMLFQISEDVSKLELKSF KFFLSQEIPRCRVNDDSNLFDIFIEMEKRVILGERNLDTLKRICDLINRSLLKKITDYEE LSQERTMIPQRSLDEISNDMSQLLVGEKSLRIPPMSDSPREQNCGSETSDKVYQMESKPR GYCLIFNNYDFSIARKEVPKLHSIKDRNGTDLDADALHQTFSELHFEIVPFRDSTAKEIC DVLKSYQSMDHTTRDCFICCILSHGDKGIIYGCDGQGVPICELTSYFTGSKCPSLAGKPK IFFIQACQGDNYQKGIAVETDSEQNEACYESDSCQKRYIPDDADFLLGMATVNDCVSYRN PMEGTWYIQTLCQSLRERCPRGEDILSILTEVNFEVSSKDDRRNMGKQMPQPTFTLRKKL IFPCD NT seq 1458 nt NT seq  +upstreamnt  +downstreamnt atgaatttcagtaaatgcctctataatattggagaacagctggacagtgatgagctggct tccctcaaattcctgagcatggactacatcccccagaagaagcaggagcccatcaaggat cccctgatgttattccagagactccaggaaaagagactgttggaggaaaacaacctgtcc ttcttgaaggagcttcttttccgaatcaacagactggacctgctggtcacctacctggac accagcaagcaggagatggagcaagagcttcagatcccgggcagagcccagatctctgct tacagggtcatgctttttcagatttcagaagatgtaagcaaactggaattgaagtccttt aagttttttttgagccaggagatccctagatgtagagtgaacgatgattcgaacttgttt gatattttcatagagatggagaagagggtcatcctcggggaaagaaatttggacaccctg aaaagaatctgtgacctaataaacaggagcctgctgaagaaaatcacggattatgaagaa ttaagccaagagcgaacaatgatcccgcaaagaagtctagatgaaatttcaaatgatatg tctcagttgcttgtaggagagaaatcgctgaggataccgccaatgtcagactctccaagg gaacagaactgtggatcagagacatcggacaaagtttaccaaatggaaagcaaacctcga ggatattgtttgatctttaacaattatgactttagcatagcacggaaggaagtgcccaaa cttcacagcattaaggataggaatggaacagacttggatgcagatgctttgcatcagacc tttagtgagcttcattttgagatcgtgcctttcagagactctacggctaaggaaatctgt gacgttctcaaatcctaccaaagcatggaccacactaccagggactgcttcatctgctgc atcctctcccatggagacaagggcatcatctacggctgtgatggacagggagtccccatc tgtgagctcacctcttacttcactggttctaagtgcccttcccttgcagggaagcccaag atcttttttattcaggcttgtcaaggggataactaccagaaggggatcgctgttgagacc gactctgaacagaatgaagcgtgttatgaatcagactcctgtcagaagagatatatccca gacgatgctgactttctgctggggatggccactgtgaatgattgtgtttcctaccgaaac cccatggagggaacgtggtatatccagacactttgccagagcctgagagaaagatgtcct aggggagaagatattctcagcatccttactgaagtgaattttgaagtgagcagtaaggat gacaggagaaacatgggcaaacagatgccacagccgaccttcacgctgcggaaaaagctc attttcccttgtgactga

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