Mustela lutreola (European mink): 131828679
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Entry
131828679 CDS
T09578
Symbol
RET
Name
(RefSeq) proto-oncogene tyrosine-protein kinase receptor Ret
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
mlk
Mustela lutreola (European mink)
Pathway
mlk04010
MAPK signaling pathway
mlk04020
Calcium signaling pathway
mlk04151
PI3K-Akt signaling pathway
mlk05200
Pathways in cancer
mlk05216
Thyroid cancer
mlk05223
Non-small cell lung cancer
mlk05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mlk00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
131828679 (RET)
04020 Calcium signaling pathway
131828679 (RET)
04151 PI3K-Akt signaling pathway
131828679 (RET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
131828679 (RET)
05230 Central carbon metabolism in cancer
131828679 (RET)
09162 Cancer: specific types
05216 Thyroid cancer
131828679 (RET)
05223 Non-small cell lung cancer
131828679 (RET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mlk01001
]
131828679 (RET)
Enzymes [BR:
mlk01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
131828679 (RET)
Protein kinases [BR:
mlk01001
]
Receptor tyrosine kinases (RTK)
RET family
131828679 (RET)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD1
RET_CLD4
RET_CLD3
Pkinase
RET_CRD
Cadherin
RIO1
Pkinase_fungal
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
131828679
NCBI-ProteinID:
XP_059025508
LinkDB
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Position
4:37224379..37276034
Genome browser
AA seq
1117 aa
AA seq
DB search
MAKATATAGAAGLRLLLLLPLFGEAPLGLYFSRDAYWEKLYVDQPAGMPLLYVHALRDTP
EEVPSFRLGQHLYGIAYRARLQENDWIRIEEDTGLLYLNRSLDHSAWERLSIRNGGFPVL
TIYLQVFLSSAFLREGECQWPGCARVYFSFINTSFPACSSLKPRELCFPETGVSFRIREN
RPPGTFHQFRLLPVQFLCPNISVSYRLLEGENLPFRCAPDSLEVSTRWALDRELREKYEL
VAACTVHVGAHKEQVVMVPFPVTVYDEDDSAPTFLGGLDTASAVVEFKRKEGTVVATIRV
FDADVVPASGELLRRYTSTLLPGDTWALQTFRVEHSPNETLAQANGSFVRATVHDYRLVL
NRSLPISESRSLQLAVLVNDSDFQGPGEGVLRLRFNVTVLPVSLHLPSAYSFTMSRRARR
FAQIGKVCVDNCQEFSGIHVQYKLQLSSANCSVLGVVTSTEDTSGTLFVNDTEALQRPDC
SQLQYTVVAADRPSRRQTQAPLVVTVEGTYVAEEPGCPLSCAVSKRRPECEECGGLGSLT
GRCEWRQGDGKGITRNFSTCSPSIKTCPDGHCDAVESRNVNICPQDCLRGGSIIGGHEPG
ERWGIKAGFGICNCFPEEKKCFCEPEDSQDPLCDELCRTVIAAAVLFSFIVSMLLSTFCI
HRYHKNAHKPPIASAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKIPEDPKW
EFPRKNLVLGKTLGEGEFGKVVKATAFRLKGKAGYTTVAVKMLKENASPSELRDLLSEFN
LLKQVNHPHVIKLYGACSQDGPLFLIVEYAKYGSLRGFLRESRKAGPGDMGSGGSRSSSY
LDSPGERALTMGDLISFAWQISRGMRYLAEMKLVHRDLAARNVLVAEGRKMKISDFGLSR
DVYEEDSYVKRSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP
ERLFNLLKTGYRMERPDNCSEEMYGLMLQCWKQEPDKRPVFADISKDLEKMMVKNRDYLD
LAASTPSDSLLYDDGLSEEETPLVDCNSAPLPRALPSTWIENKLYGMSDPNWPEESPVPL
TRADGTNTVCPRYANDSVYANWMVSPSAAQLTDAFDS
NT seq
3354 nt
NT seq
+upstream
nt +downstream
nt
atggcgaaggcgacggcgacggccggcgctgcggggctgcggttgctgctgctgctgccg
ctgttcggcgaagctccgctgggactctacttctccagggacgcttactgggagaaactg
tatgtggaccagccagctggcatgcccctgctctatgtccacgccctgcgggacacccct
gaggaggtgcccagcttccgcctgggccagcacctctacggcatcgcctaccgtgcgagg
ctgcaggagaacgactggatccgcattgaggaggacactggccttctctaccttaaccgg
agcctggaccacagcgcttgggagaggctcagcatccgcaatggtggcttcccggtgctc
accatctacctccaggtcttcctgtcgtctgcgttcctgcgtgagggcgagtgccagtgg
ccaggctgtgcccgggtgtacttctccttcatcaacacctccttcccggcttgcagttcc
ctcaaaccccgggagctctgctttcccgagacaggcgtctccttccgcatcagagagaac
aggcctcctggcaccttccaccaattccggctgctgcctgtgcaattcctctgccccaac
atcagcgtgtcctacaggctcctagaaggtgagaatctgcccttccgctgcgccccagac
agcctggaggtgagcacacgctgggccctggaccgcgagctgcgggagaagtacgagctg
gtggccgcgtgcacggtgcacgtcggcgcacacaaggagcaggtggtgatggtgcccttc
cccgtgaccgtgtacgatgaggacgactcggcacccaccttcctcgggggcctggacacc
gccagcgctgtggtggagttcaagaggaaggagggcaccgtggtggccacaatacgtgtc
ttcgatgcagacgtggtgccggcctctggggagctgctgaggcggtacacaagcacacta
ctgccaggggacacctgggccctgcagactttccgtgtcgagcactcaccgaacgagacc
ttggcccaggctaatggcagcttcgtgcgagcaactgtgcatgactacaggctggttctc
aaccggagcctccccatctcggagagccgctccctgcagctggctgtgctggtcaatgac
tcggacttccagggccccggtgagggcgtcctccgcctccgtttcaacgtgaccgtgctg
cctgtcagcctgcacttacccagcgcctactccttcactatgagcaggcgggcccgccgc
tttgcccagattgggaaagtctgcgtggataactgccaggagttcagcggcatccacgtg
cagtacaagctgcagctctccagcgccaactgcagcgtcctgggggtggtcacctccacc
gaggacacctcaggaaccctgttcgtgaatgacacagaagccctgcagcggcctgactgt
tctcaactgcagtacacagtggtggccgccgaccggccaagccgcaggcagacccaggcc
ccgctggttgtcaccgtggaggggacatatgtggccgaggaaccaggctgccccctgtcc
tgtgcagtcagcaagaggcggcctgagtgtgaggagtgtggcggcctgggctctctgacg
ggcaggtgcgagtggagacagggagatggcaaaggaattaccaggaacttctccacctgc
tcccccagcatcaagacctgccccgatggccactgtgatgctgtggagagcagaaacgtc
aacatctgcccccaggactgcctccggggtggcagcatcattggtgggcacgagcctggg
gaacgctgggggataaaagctggcttcggtatctgcaactgtttccccgaagagaagaaa
tgcttctgtgaacctgaagacagccaggacccgctgtgtgacgagctgtgccgcacggtg
atcgcggcagctgtgctcttctccttcatcgtctccatgctgctctccaccttctgcatc
caccgctaccacaagaatgcccacaagccacccatcgcctctgctgagatgaccttccgc
cggccggcccaggccttcccggtcagctactcctcgtcgggcgcccgccggccctccctg
gactccatggagaaccaggtctctgtggacgcctttaagatcccggaggatccaaagtgg
gaattccctcggaagaacttggttcttggaaaaactctgggagaaggcgaatttggaaaa
gtggttaaggcaacagccttccggcttaaaggcaaagcagggtacacgactgtggctgtg
aagatgctgaaagagaacgcctccccaagtgagctgcgggacctgctgtcagagttcaac
ctcctgaagcaggtcaaccacccgcatgtcatcaagctgtatggggcctgcagccaggat
gggccactcttcctcattgtggagtacgccaagtacggctccctgcggggcttcctccgg
gagagccgcaaggctggcccgggcgacatgggcagcgggggcagccgcagctccagctac
ctggacagccccggggagcgagccctgaccatgggcgacctcatctccttcgcctggcag
atctctcgggggatgcggtacctggcggagatgaagcttgtccatcgggacttggcagcc
agaaatgttctggtagccgaggggcggaagatgaagatttcggatttcggcctgtcccga
gatgtttatgaagaggattcctatgtgaagaggagcaagggtcggattccagtcaaatgg
atggcaatcgagtctcttttcgatcacatctacaccacccaaagtgacgtgtggtccttt
ggtgtcctgctatgggagattgtgactctagggggcaacccctaccctgggatacctcca
gagcggctcttcaaccttctaaagacaggctaccggatggagaggcctgacaactgcagt
gaggagatgtatggcctaatgctacagtgctggaagcaggaaccggacaagaggccggtg
tttgctgacatcagcaaagacctggagaagatgatggttaagaacagagactacttggac
ttggccgcgtccaccccatctgactccctgctttacgacgacggcctctcggaggaggag
acgcccctggtggactgtaatagcgctcccctccctcgagccctcccctccacgtggatt
gaaaacaaactctatggcatgtcagacccgaactggcctgaagagagtcctgtaccactc
acgcgagctgatggcactaacactgtgtgtccaagatatgcaaatgatagtgtatatgct
aactggatggtttcaccctcagcggcacaattaacggacgcatttgatagttaa
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