KEGG   Mustela lutreola (European mink): 131838541
Entry
131838541         CDS       T09578                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4 isoform X1
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
mlk  Mustela lutreola (European mink)
Pathway
mlk01522  Endocrine resistance
mlk04110  Cell cycle
mlk04115  p53 signaling pathway
mlk04151  PI3K-Akt signaling pathway
mlk04218  Cellular senescence
mlk04530  Tight junction
mlk04660  T cell receptor signaling pathway
mlk04933  AGE-RAGE signaling pathway in diabetic complications
mlk04934  Cushing syndrome
mlk05160  Hepatitis C
mlk05162  Measles
mlk05163  Human cytomegalovirus infection
mlk05164  Influenza A
mlk05165  Human papillomavirus infection
mlk05166  Human T-cell leukemia virus 1 infection
mlk05167  Kaposi sarcoma-associated herpesvirus infection
mlk05169  Epstein-Barr virus infection
mlk05200  Pathways in cancer
mlk05203  Viral carcinogenesis
mlk05212  Pancreatic cancer
mlk05214  Glioma
mlk05218  Melanoma
mlk05219  Bladder cancer
mlk05220  Chronic myeloid leukemia
mlk05222  Small cell lung cancer
mlk05223  Non-small cell lung cancer
mlk05224  Breast cancer
mlk05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:mlk00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    131838541 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    131838541 (CDK4)
   04115 p53 signaling pathway
    131838541 (CDK4)
   04218 Cellular senescence
    131838541 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    131838541 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    131838541 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    131838541 (CDK4)
   05203 Viral carcinogenesis
    131838541 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    131838541 (CDK4)
   05225 Hepatocellular carcinoma
    131838541 (CDK4)
   05214 Glioma
    131838541 (CDK4)
   05220 Chronic myeloid leukemia
    131838541 (CDK4)
   05218 Melanoma
    131838541 (CDK4)
   05219 Bladder cancer
    131838541 (CDK4)
   05224 Breast cancer
    131838541 (CDK4)
   05222 Small cell lung cancer
    131838541 (CDK4)
   05223 Non-small cell lung cancer
    131838541 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    131838541 (CDK4)
   05160 Hepatitis C
    131838541 (CDK4)
   05164 Influenza A
    131838541 (CDK4)
   05162 Measles
    131838541 (CDK4)
   05163 Human cytomegalovirus infection
    131838541 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    131838541 (CDK4)
   05169 Epstein-Barr virus infection
    131838541 (CDK4)
   05165 Human papillomavirus infection
    131838541 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    131838541 (CDK4)
   04934 Cushing syndrome
    131838541 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    131838541 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mlk01001]
    131838541 (CDK4)
Enzymes [BR:mlk01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     131838541 (CDK4)
Protein kinases [BR:mlk01001]
 Serine/threonine kinases: CMGC group
  CDK family
   131838541 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 131838541
NCBI-ProteinID: XP_059040783
LinkDB
Position
8:56185589..56188527
AA seq 303 aa
MATPRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFSPRGPRPVQSVVPEMEESGAQLMLEMLTFNPHKRISAFRALQHSYLQKPEG
NPE
NT seq 912 nt   +upstreamnt  +downstreamnt
atggctactcctcgatatgagccagtggctgagattggtgttggtgcctatggaacggta
tacaaggcccgtgatccccacagtggacacttcgtggccctcaagagcgtgagagtccct
aatggaggaggtgctggagggggccttcccatcagcacagttcgtgaggtggccttactg
aggcggctggaggcttttgagcatcccaacgttgttcggctgatggatgtctgtgccacc
gcccgaactgatcgggagaccaaagtgaccctggtgtttgagcacgtggaccaagacctg
aggacatatctggacaaggcaccccccccgggcttgccagtggagaccatcaaggatctc
atgcgccagtttctaagaggcctagatttccttcatgccaactgcattgttcaccgagac
ctgaagccagagaacattctggtgaccagtggtgggacagtgaagctggctgactttggc
ctggccagaatctacagctaccagatggcacttacacctgtggttgttacactctggtac
cgtgctccagaagttcttctgcagtctacatatgcaacacctgtggacatgtggagcgtt
ggctgtatcttcgcagagatgtttcgtcgcaagcctctcttctgtggaaactctgaagct
gaccagttaggcaaaatctttgacctgatcgggctgcctccagaggatgactggccccga
gatgtatctctaccccgaggagccttttcccccagagggccccgtccggtgcagtcagtg
gtacctgagatggaggagtctggagcacagctaatgctggagatgctgacttttaaccca
cacaagcgaatctctgccttccgagccctgcagcactcttacctacaaaagccagaaggt
aacccagagtga

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