Mycobacterium lepromatosis: MLPF_0926
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Entry
MLPF_0926 CDS
T08064
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mlm
Mycobacterium lepromatosis
Pathway
mlm00010
Glycolysis / Gluconeogenesis
mlm00020
Citrate cycle (TCA cycle)
mlm00620
Pyruvate metabolism
mlm00785
Lipoic acid metabolism
mlm01100
Metabolic pathways
mlm01110
Biosynthesis of secondary metabolites
mlm01120
Microbial metabolism in diverse environments
mlm01200
Carbon metabolism
mlm01210
2-Oxocarboxylic acid metabolism
Module
mlm_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mlm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MLPF_0926 (aceE)
00020 Citrate cycle (TCA cycle)
MLPF_0926 (aceE)
00620 Pyruvate metabolism
MLPF_0926 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MLPF_0926 (aceE)
Enzymes [BR:
mlm01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MLPF_0926 (aceE)
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
UKN41923
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Position
908608..911421
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AA seq
937 aa
AA seq
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MTTEFARPDLAKNPSSANNSDRVQVIREGVASYLPDIDPEETAEWLESFDELLERSGPSR
ARYLMLRLLERAGEQRVTIPALTWTDYVNTIPTELEPWFPGDEDIERRYRTWIRWNAAIM
VHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKSHPSGGDQVFIQGHASPGIYARAF
LEGRLSADQLDGFRQEHSHPGGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNRY
MHDRGIKDTSDQHVWCFLGDGEMDEPESRGLAHVAALEDLDNLIFVINCNLQRLDGPVRG
NGKIIQELESCFRGAGWNVIKVVWGREWDALLHADRDGALVDLMNATPDGDYQTYKANDG
RFVRDHFFGRDPRTKALVEHMSDQEIWNLKRGGHDYRKVYAAYRAAVDHRGQPTVILAKT
IKGYALGKHFEGRNATHQMKKLTLEDLKEFRDTQRIPISDAQLEENPYLPPYYHPGPDSP
EIRYLLDRRRALGGFLPERRTKSKALTLPGRDTYAALKTGSGQQEIATTMAIIRTFKEVL
RHKEVGPRIVPIIPDEARTFGMDSWFPSLKIYNHNGQLYTAVDAQLMLAYTESEVGQILH
EGIDEAGSVGSFIAAGTSYSTHNEPMIPIYIFYSMFGFQRAGDGLWAAADQMARGFLLGA
TAGRTTLTGEGLQHADGHSLLLAATNPAVVTYDPAFAYEIAYIVENGLARMFGEDPENVF
FYITIYNEPYPQPPEPENFDPDGVLRGMYRYHTAKEERSNKAHILASGVSMPAALTAAEM
LSAQWDVAADVWSVTSWGELNREGMSIDTARLRYPDQPTSVPYVTQVLSEARSDNAGPVI
AVSDWMRAVPEQIRPWVPGTYVTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALARD
GEIDPSVPVAAVRQYQIDDLRPPRADIESGTGSLELA
NT seq
2814 nt
NT seq
+upstream
nt +downstream
nt
ttgacaaccgagttcgcgcgcccggatctggccaaaaacccgagtagcgcaaacaattcc
gaccgcgttcaggtgatccgcgaaggtgtggcctcgtatttgcccgatatcgaccccgag
gagacagcggagtggctggagtccttcgacgaattgctggaacgctcggggccgtcgcgg
gcacgatacctgatgctacgactattggagcgagccggcgagcagcgagtgacgatcccg
gcgctgacatggaccgactacgtcaacaccatcccaaccgagctcgagccgtggttcccc
ggcgatgaggacattgaacgtcgctaccgtacctggatcagatggaacgcggcaattatg
gtgcaccgcgcgcaacgaccgggtgtgggcgtcggtggtcatatctcgacctacgcttcg
tccgcggcgctctacgaggtggggttcaaccactttttccggggcaagtcgcatcccagc
ggcggagatcaggtgttcatccagggtcacgcgtcccccggaatttacgcacgcgccttc
ctggaaggccgattgtccgcagaccagcttgatggtttccgccaggagcacagtcatccc
ggcggcgggttgccgtcctacccgcacccacgactgatgcccgacttctgggaattcccc
accgtatcgatgggtctaggtccgctcaacgccatttaccaggcacggttcaaccgctat
atgcatgaccgaggcatcaaggacacctccgaccagcacgtgtggtgttttttaggcgac
ggtgaaatggacgagcccgagagccgcgggctcgcacatgtcgcagccctcgaagacctg
gacaacctgatcttcgtgatcaactgcaatctgcagcgcctcgacggtccagtacgtggc
aacggcaagatcatccaggagttggagtcatgcttccgcggagccggctggaacgtcatc
aaggtagtgtggggccgtgaatgggacgcgctgctacatgccgaccgggacggcgccctg
gtcgacctaatgaacgccacccctgatggtgattaccaaacatacaaagccaacgatgga
cgctttgtccgcgaccacttcttcgggcgcgacccgcgcaccaaggcgctcgtggaacac
atgagcgaccaggagatctggaacctcaagcgcggcggtcacgactaccgtaaagtttac
gccgcctaccgcgctgccgtcgaccacaggggacaaccaacagtgatcctggccaagacc
atcaagggctacgcgctgggcaagcatttcgagggccgcaatgccactcaccaaatgaaa
aagcttacgctggaagatcttaaggagtttcgcgatacccagcggattccgatttcagac
gcccaactggaggaaaatccttacctgccaccgtactaccaccccggccccgactcaccg
gaaatccgttatctgctcgaccggcgccgcgctctcggaggtttcctgcccgagcgccgg
acaaagtccaaagcactgacgcttcccggccgcgacacctacgccgcgttgaagaccgga
tcgggtcagcaggaaatcgcgaccaccatggcgatcatacgcacattcaaagaagtgttg
cgacacaaagaagtcggcccacggatcgtcccaatcattcccgacgaagcgcgcacgttc
ggcatggactcgtggtttccgtcgttgaagatttataaccacaacggccaactgtacact
gctgtcgacgcacaactgatgctggcgtacacggagagcgaagtcggacagatcctgcac
gaaggaattgacgaggccgggtcggtggggtcattcatcgcagcaggcacatcgtattcg
acgcacaacgagcctatgattccaatctacatcttctattcgatgttcgggttccagcgc
gccggcgacggcctgtgggctgcagccgaccaaatggcgcgcggcttcctactcggggcc
accgcgggacgtaccacgctgaccggcgagggactacaacacgccgacggccactcgttg
ctgttagcggccaccaatccggcagtcgtcacgtacgacccggcgttcgcctacgaaatc
gcctatatcgtcgaaaacgggctggcccgaatgtttggggaggacccggaaaatgtgttc
ttttacatcaccatctacaacgaaccatacccacagccacccgaaccagagaacttcgat
cccgacggcgtactgcgcggaatgtaccgctaccacacggctaaggaggaacgttccaac
aaggcgcacatcttggcctccggagtgtcaatgcccgcggcattgacggcagccgagatg
ctgtccgcccagtgggatgtcgctgccgacgtatggtcggtgaccagttggggcgaactg
aaccgcgaagggatgtccatcgacacggcccggctgcgttaccccgaccaaccgacgagc
gtcccctacgtaacccaggtcttatccgaagcccgttcagataacgccggaccggtaatc
gccgtatcggactggatgcgcgcagtgcccgaacagatccggccatgggttcctggcacc
tacgtcacgctgggcactgacgggttcggtttttccgacacccgtccggccgctcggcgc
tatttcaacaccgatgccgaatcacaggttgtagcggtattggaggcgctggcacgtgac
ggtgagatagacccgtcggtgccggtcgcggccgtacgtcaataccagatcgacgacttg
cgcccccccagagcagacatcgaatccgggactggaagcttagaactagcataa
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