Mycobacterium lentiflavum: MJO58_16805
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Entry
MJO58_16805 CDS
T08800
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mlw
Mycobacterium lentiflavum
Pathway
mlw00010
Glycolysis / Gluconeogenesis
mlw00020
Citrate cycle (TCA cycle)
mlw00620
Pyruvate metabolism
mlw00785
Lipoic acid metabolism
mlw01100
Metabolic pathways
mlw01110
Biosynthesis of secondary metabolites
mlw01120
Microbial metabolism in diverse environments
mlw01200
Carbon metabolism
mlw01210
2-Oxocarboxylic acid metabolism
Module
mlw_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mlw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MJO58_16805 (aceE)
00020 Citrate cycle (TCA cycle)
MJO58_16805 (aceE)
00620 Pyruvate metabolism
MJO58_16805 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MJO58_16805 (aceE)
Enzymes [BR:
mlw01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MJO58_16805 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ULP40632
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All DBs
Position
3596747..3599536
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AA seq
929 aa
AA seq
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MTTEFARHDLAKTPSNGSEPDRVRVIRDGVASYLPDIDPEETSEWLESFDELLERSGPGR
ARYLMLRLLERAGEQRVSLPALTSTDYVNTIPTELEPWFPGDEDVERRFRAWIRWNAAIM
VHRAQRPGIGVGGHISTYASSAALYEVGFNHFFRGKAHPGGGDQVFIQGHASPGIYARAF
LEGRLTADRLDGFRQEHSHPGGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNHY
LHDRGIKDTSDQHVWAFLGDGEMDEPESRGLIQVAANEALDNLTFVINCNLQRLDGPVRG
NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDGDYQTYKANDG
AYVRDHFFGRDPRTKALVESMTDSEIWNLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKT
IKGYSLGAHFQGRNATHQMKKLAIEDLKYFRDAIRIPISDAQLEEDPYLPPYYHPGPDAP
EIRYMLDRRRQLGGFLPERPTKAKALKLPSRDIYAPLKKGSGHQEVATTMALVRTFKEVM
RDKEIGPRIVPIIPDEARTFGMDSWFPSLKIYNRLGQLYTAVDADLMLAYKESEIGQILH
EGINEAGSTASFTAAGTSYATHNEPMIPLYIFYSMFGFQRTGDGFWAAADQMARGFVLGA
TAGRTTLTGEGLQHADGHSLLLAATNPAVVSYDPAFAYEIAYIVESGLARMFGPNPENIY
FYITIYNEPYVQPAEPHNLDPEGVLRGIYRYQMASERRTNTAQILASGVAMPSAVKAAEM
LAAEWDVAADVWSVTSWGELNRDGLAIQQAQLRYPDKPAGVPYITKALEGATGPVIAVSD
WMRGVPEQIRQWVPNTFVTLGTDGFGFSDTRPAARRFFNTDAESQVVAVLEALARDGEID
PSVPLAAARQYRIDDVQAAPKQTSDPGVA
NT seq
2790 nt
NT seq
+upstream
nt +downstream
nt
ttgacgaccgagttcgcgcgccacgatctggccaaaaccccaagcaacggaagcgaaccc
gatcgcgtccgggtgatccgagacggtgtcgcgtcgtatctgcccgacatcgatcccgag
gaaacgtcggagtggctggagtccttcgatgaactgctggagcgctcgggtccgggccgg
gcccgctacctgatgttgcggttgctggaacgcgcgggcgaacagcgggtgtcgctgccg
gcgctgacgtccaccgactacgtgaacaccatcccgaccgagctggaaccgtggttcccc
ggcgacgaggacgtcgaacgtcgcttccgggcctggatccgctggaacgccgcgatcatg
gtgcaccgcgcccagcgtccgggaatcggcgtgggcggccacatttcgacgtacgcctcg
tcggcggcgctgtacgaggtcggtttcaaccacttcttccgcggcaaggcgcacccgggc
ggcggcgaccaggtgttcatccagggccacgcgtcccccgggatttacgcgcgcgcgttc
ctggaaggccggctgaccgctgaccgactcgacggctttcggcaggagcacagccacccg
ggcggcgggctgccgtcgtatccccacccgcggctgatgcccgacttctgggagttcccg
acggtgtcgatgggcctgggcccgatgaacgccatctaccaggcccgcttcaaccactac
ctgcacgaccgcggcatcaaggacacctcggatcagcatgtgtgggcgttcctcggcgac
ggcgagatggacgaaccggagagccgcggcctgatccaggtggccgccaacgaggcgctg
gacaatttgacgttcgtcatcaactgcaacctgcagcgcctcgacggtccggtgcgcgga
aacggcaagatcattcaggaactggagtcgttcttccgcggcgccggatggaacgtgatc
aaggtggtctggggccgcgagtgggacgccctgctgcacgccgaccgcgacggcgcgctg
gtgaacctgatgaacaccacgcccgacggcgactaccagacctacaaggctaacgacggc
gcctacgtccgcgaccacttcttcggccgcgatccgcgcaccaaggcgctcgtcgaatcg
atgaccgattccgagatctggaatctcaagcgcggtggccacgactaccgcaaggtctat
gccgcctaccgcgccgccgtcgaccacaagggacagccgacggtgatcctggccaagacc
atcaagggctactcgctgggcgcgcacttccagggtcgtaacgccacgcatcagatgaaa
aagcttgcgatagaagaccttaagtatttccgcgacgccatccggattccgatcagcgac
gctcaactggaggaagacccctacctgccgccctactatcaccccggacccgatgccccc
gagatccgctacatgctggaccggcgtcgccagctaggcggcttcctgcccgagcgcccg
acgaaagccaaggcgctcaagcttcccagccgcgacatctacgcaccgctgaagaagggc
tcggggcaccaagaggtcgccaccacgatggcactggtgcgcaccttcaaagaagtgatg
cgggacaaggagattggcccgcgtatcgtgccgatcattcccgacgaggcccgcacgttc
ggcatggactcgtggttcccgtcgctgaagatctacaaccgcctcggccagctctacacg
gcggtggacgccgatttgatgttggcgtacaaggaaagtgaaatcgggcagatcctgcac
gagggcatcaacgaggccggctcgactgcgtcgttcaccgcggccggcacgtcgtacgcg
acgcacaacgagccgatgatcccgctctacatcttctactcgatgttcgggttccagcgc
accggcgacgggttctgggctgcggccgaccagatggcgcgcggatttgtgttgggggcc
accgccggtcgcaccacgctgaccggcgagggcctgcagcacgccgacggtcactcgcta
ctgctggccgccacgaacccggcggtcgtctcgtacgacccggcgttcgcctacgagatc
gcctacatcgtcgagagcgggctggcgcggatgttcggccccaacccggagaacatctac
ttctacatcaccatctacaacgagccctacgtacagccggccgagccgcacaacctcgat
cccgagggcgtgctgcgcggaatctaccggtaccagatggccagcgagcggcgcaccaac
accgcgcagatcctggcctccggggtggcgatgccgtcggcggtgaaggcggccgagatg
ctggccgccgagtgggacgtcgccgccgacgtgtggtcggtgaccagttggggtgagctc
aatcgcgacgggctggcgatccagcaggcccagctgcgttatcccgacaagccggccggc
gtcccgtacatcacgaaagcgctcgaaggcgccaccgggccggtgatcgccgtgtcggac
tggatgcgtggggtgcccgagcagatccggcagtgggtgccgaataccttcgtcacgctg
ggcaccgacgggttcggcttctccgacacccgcccggcggcccggcggttcttcaacacc
gacgcggagtcgcaggtggtggcggtgctcgaggcgctggcccgcgacggcgagatcgac
ccgtcggtgccgctcgcggcggcgcgtcagtaccggatcgacgacgtccaggccgcgccg
aagcagacgtccgaccccggcgtcgcctag
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