Mirounga leonina (Southern elephant seal): 117999978
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Entry
117999978 CDS
T07472
Symbol
ALOX12
Name
(RefSeq) polyunsaturated fatty acid lipoxygenase ALOX12 isoform X1
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx00590
Arachidonic acid metabolism
mlx01100
Metabolic pathways
mlx01523
Antifolate resistance
mlx04726
Serotonergic synapse
mlx04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
117999978 (ALOX12)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
117999978 (ALOX12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
117999978 (ALOX12)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
117999978 (ALOX12)
Enzymes [BR:
mlx01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
117999978 (ALOX12)
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Paralog
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Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
117999978
NCBI-ProteinID:
XP_034845307
LinkDB
All DBs
Position
Unknown
AA seq
663 aa
AA seq
DB search
MGRYRIRVATGAWLFSGSHNSVQLWLVGACGEAELQLQLRPARGQEEEFDRDVPKDLGPL
QFVKLRKHHSLVDDAWFCDLITVQGPGACEEAAFPCYRWVQGQGVLSLPEGTARLAGDNA
LDVFQKHRENELKERQELYCWDTWKEGLPLTIAAGCQDDLPPNMRFHEDKRLDFEWALKA
GALEMVLKRVYTLLSSWNRPEDFDQIFWGQKSALAEKVHQCWRDDELFGYQFLNGANPML
LRRSTSLPRRLVLPPGLEALGAQLERELQNGSLFEADFILLDGIPANVIRGEKQYLAAPL
VLLRMTPNGKLLPVVIQIQPPSPSTPTPQLFLPSDPPFAWLLAKVWVRNADFQLHQLQYH
LLNTHLVAEVIAVATMRCLPGLHPVFKLLIPHIRYTMEINTRARSQLISEGGIFDKAVST
GGGGHVQLLRRAMAQLTYRSLCPPDDLADRGLLGIPSALYAHDALRLWGITARYVEGIVH
LFYHRDDIVRGDPELQAWCREITEVGLCQAQDRGFPISFQSRKQLCHFLTMCVFTCTAQH
GAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMTTVMGSLPDVRQACLQMTITWHLGRR
QPDMVPLGHHKEKYFSSPKAKAVLNQFQTDLESLEREITARNEQLDLPYDYLKPSHIENS
VTI
NT seq
1992 nt
NT seq
+upstream
nt +downstream
nt
atgggccgctaccgcatccgcgtggccaccggggcctggctcttctcggggtcgcacaac
agcgtgcagctgtggctggtcggggcgtgcggggaggcggagctgcagctgcagctgcgg
ccggcgcggggccaggaggaggaatttgatcgcgacgttcccaaggacttggggcccctg
cagttcgtgaagctgcgcaaacaccactccctggtggacgacgcgtggttctgcgacctc
atcacagtgcagggcccgggtgcctgcgaggaggccgccttcccctgctaccgctgggtg
cagggccagggcgtgctgagcctgcccgagggcaccgcacgcctggcaggagacaatgcc
ctggacgtgttccagaagcatcgagagaacgaactgaaggaaagacaagagctgtactgc
tgggacacctggaaggaggggttacccctgaccatagctgccgggtgtcaggacgatctg
cctccaaacatgagattccatgaggacaagaggctggacttcgagtgggcactgaaggcg
ggagcgctagagatggtcctcaaacgtgtctacaccctcctgagctcctggaatcgtccg
gaggattttgatcagatcttctggggccagaagagcgccctggctgagaaggtccaccag
tgctggcgggacgatgagctttttggctaccagttcctcaacggcgccaaccccatgctg
ttgagacgctccacctctctgccccgccggctcgtgctgccccccgggctggaggcactg
ggggcccagctggagagagagctccagaacggttccctgtttgaggccgacttcatcctg
ctggatggaattccagccaacgtgatccggggcgagaagcagtacctggccgcccccctc
gtcctgctgcggatgacacccaatgggaagctgctgcccgtggtcatccagatccagcct
cccagccccagcacccccaccccccagctgttcctgccctcagatcccccattcgcctgg
ctcctggcaaaggtctgggtccgaaatgccgactttcaactgcaccagctccagtatcat
ctgctgaacactcacctggtggccgaggtcattgctgtggccaccatgaggtgcctcccg
gggctgcaccctgtcttcaagctcctgatcccgcacatccgctacaccatggagatcaac
acccgggccagatcccagctcatctcagaaggaggaatatttgacaaggcggtgagcacc
ggcggagggggccacgtgcagttgctgcgtcgggccatggctcagctgacctaccgctcc
ctctgtcctcccgacgacctggctgaccgtggcctgctgggaatcccaagtgccctctac
gcgcatgatgctttacggctctgggggatcactgcccggtacgtggagggcatcgtccac
ctcttctaccacagggatgacatcgtgagaggggacccggagctgcaggcctggtgtcgg
gagatcactgaggtggggctgtgccaggcccaggaccgaggtttccccatctccttccag
tcccggaagcaactctgccatttccttaccatgtgtgtcttcacatgcactgctcagcac
ggggccatcaaccagggccagctggactggtatgcctgggtccctaatgccccatgcaca
atgcggatgcccccacccaccaccaaggaagatgtaacaatgaccacggtgatgggctca
ctacctgatgtccgacaggcctgtcttcaaatgaccatcacatggcatctggggcgccgc
cagccagacatggtgcctctggggcatcacaaagaaaaatatttctcaagccccaaggcc
aaggctgtattaaaccaattccaaacggatttggaaagcctggaaagagagattacagcc
cggaatgagcaactcgacctgccctatgactacctgaagcccagccacatagagaacagt
gtcaccatctga
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