KEGG   Mirounga leonina (Southern elephant seal): 118006827
Entry
118006827         CDS       T07472                                 
Name
(RefSeq) platelet-derived growth factor receptor beta-like isoform X1
  KO
K05089  platelet-derived growth factor receptor beta [EC:2.7.10.1]
Organism
mlx  Mirounga leonina (Southern elephant seal)
Pathway
mlx01521  EGFR tyrosine kinase inhibitor resistance
mlx04010  MAPK signaling pathway
mlx04014  Ras signaling pathway
mlx04015  Rap1 signaling pathway
mlx04020  Calcium signaling pathway
mlx04072  Phospholipase D signaling pathway
mlx04151  PI3K-Akt signaling pathway
mlx04510  Focal adhesion
mlx04540  Gap junction
mlx04630  JAK-STAT signaling pathway
mlx04810  Regulation of actin cytoskeleton
mlx05165  Human papillomavirus infection
mlx05200  Pathways in cancer
mlx05206  MicroRNAs in cancer
mlx05214  Glioma
mlx05215  Prostate cancer
mlx05218  Melanoma
mlx05230  Central carbon metabolism in cancer
mlx05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:mlx00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118006827
   04014 Ras signaling pathway
    118006827
   04015 Rap1 signaling pathway
    118006827
   04630 JAK-STAT signaling pathway
    118006827
   04020 Calcium signaling pathway
    118006827
   04072 Phospholipase D signaling pathway
    118006827
   04151 PI3K-Akt signaling pathway
    118006827
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    118006827
   04540 Gap junction
    118006827
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    118006827
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118006827
   05206 MicroRNAs in cancer
    118006827
   05230 Central carbon metabolism in cancer
    118006827
   05231 Choline metabolism in cancer
    118006827
  09162 Cancer: specific types
   05214 Glioma
    118006827
   05218 Melanoma
    118006827
   05215 Prostate cancer
    118006827
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    118006827
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    118006827
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mlx01001]
    118006827
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:mlx04090]
    118006827
Enzymes [BR:mlx01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     118006827
Protein kinases [BR:mlx01001]
 Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   118006827
CD molecules [BR:mlx04090]
 Proteins
  118006827
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Ig_3 ig I-set Ig_2 V-set VEGFR-1-like_Ig-like C2-set_2 VEGFR1-3_N_Ig-like TrmE_N Haspin_kinase
Other DBs
NCBI-GeneID: 118006827
NCBI-ProteinID: XP_034855532
LinkDB
Position
Unknown
AA seq 1141 aa
MTGAFHHHRDPSQQWKRKSLVSFSRQLGLGKLKSESSHSDKDTMQPPSTMPAPVLKGQVL
LLPLLLLLGPQASWGLVITPPGPELVLNVSSNFVLTCSGPAPVVWERMSQEPLQKMTKTQ
DGTFSSTLTLTNVTGIDTGEYFCTYQGSHGLEPGERKRLYIFVPDPMMGFLPVDPEELFI
FLTEITEITIPCRVTDPRLVVTLHEKKVDIPLPIPYDHQRGFSGTFEDKTYVCKTTIGDK
EVDSEAYYVYSLQVSSINVSVNAVQTVVRQGENITIMCIVTGNEVVNFEWTYPRMESGRL
VEPVTDFLFNMPSHIRSILHIPSAELGDSGTYICNVSESVNEHQDEKSINVTVVENGYVR
LLGELDPVQFAELHRSRTLQVVFEAYPPPTVMWFKDNRTLGDSNAGEISLSTRNVSETRY
VSELTLVRVKVAEAGCYTMRAFHEDAEAQLSFQLQVNVPVRVLELSESHPASGEQTVRCR
GRGMPQPHLTWSTCSDLKRCPRELPPTPLGNSSEEESQLETNVTYWPEDQEFEVVSTLRL
RRVDQPLSVRCTLHNLLGRDMQEVTVVPHSLPFKVVVISAILALVVLTVISLIILIMLWQ
KKPRYEIRWKVIESVSSDGHEYIYVDPMQLPYDSTWELPRDQLVLGRTLGSGAFGQVVEA
TAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLNVVNLLGACTKGGPI
YIITEYCQYGDLVDYLHRNKHTFLQRGSDKRRPPGAELYSNALPGGLPLPSHMSLPGESD
GGYMDMSKDESVDYVPMLDMKGGVKYADIESSSYMAPYDNYVPTAPERTCRVTLINESPV
LSYTDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMRDSNY
ISKGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQFYNAI
KRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPFSQLVLLLERLLGEGYKKKYQQVDEEF
LRSDHPAVLRSQARLPGFHGLRSPLDTSSVLYTAVQPNEGDNDYIIPLPDPKPEVADEGP
LESSPSLASSTLNEANTSSTISCDSPLEPQEEPEPQVEPELEPPLDSSCPGHRAEAEDSF
L
NT seq 3426 nt   +upstreamnt  +downstreamnt
atgacaggtgcttttcatcatcatcgcgacccctcacagcaatggaaaaggaagtctctt
gtgtcgttttcccggcaactgggacttgggaagttaaagtcagagagctcacacagtgac
aaggacaccatgcagcctccgagcaccatgccggctcctgtcctcaaaggccaggtgctg
ttgctgcccctcctgttgctgctgggcccacaggcctcctggggcctggtcatcacaccc
ccagggccagagcttgtcctcaatgtctccagcaacttcgttctgacttgctcggggccc
gctccagtggtgtgggaacggatgtcccaggagcccctgcagaaaatgaccaagacccag
gatggcaccttctccagcacactgacactgaccaatgtcactgggatagacacaggagaa
tacttttgcacctaccaaggctcccatgggctggagcctggtgaacgaaaacggctctat
atctttgtgccagatcccatgatgggttttcttccggtcgaccccgaggaactattcatc
ttcctcacggaaataactgagatcacaattccgtgccgagtgacagatccgagactggtg
gtgacactgcatgagaaaaaagtggatattccactgcccatcccctatgaccaccaacgt
ggcttctctggtaccttcgaggacaagacctatgtctgcaaaaccaccatcggggacaag
gaagtggattctgaagcctactatgtctacagcctccaggtgtcatccatcaatgtctca
gtgaatgcagtgcagactgtggtccgtcagggtgagaacatcaccatcatgtgcatcgtg
accggaaatgaggtggtcaactttgaatggacatacccacgcatggagagtgggcggctg
gtggagccagtgactgacttcctcttcaatatgccctcccacatacgctccatcctgcac
atccctagtgctgagcttggcgattcagggacctacatctgcaatgtatcggagagtgtg
aatgagcatcaagatgaaaagtccatcaatgtcactgtggtcgagaatggctacgtgcgg
ctgctgggagagctggaccccgtacaattcgcggagctgcaccgcagccggactctgcag
gtcgtgttcgaggcctacccgccgcctactgtcatgtggttcaaggacaaccgtacgcta
ggcgactccaacgcaggcgagatctccctgtccacacgcaatgtgtctgagacccggtac
gtgtcagaactgacgctggtgcgggtgaaggtggctgaggctggctgctacaccatgcgg
gccttccatgaggacgcagaggcccagctgtccttccagctgcaggtcaacgtgcctgtc
cgtgtgctggagctgagtgaaagccaccctgccagtggggagcagacggtccgctgtcgc
ggccggggcatgccccagccacacctcacctggtctacctgcagcgacctcaaaaggtgt
ccgcgcgagctgccgcccacgccgctggggaacagttcggaggaggagagccagctggag
actaacgtgacatactggcccgaggatcaggagttcgaggtggtgagcacactgcgcctg
cgccgtgtggatcagccgctgtcagtgcgctgcactctacacaacctgctgggacgcgac
atgcaggaggtcaccgtggtgccgcactctctgcccttcaaggtggtggtgatctcggcc
atcctggccttggtggtcctcacagtcatctccctcatcatcctcatcatgctctggcag
aagaagccacgttatgagatccgatggaaggtgattgaatccgtgagctccgatggccat
gagtacatctacgtggaccctatgcaattgccctacgactccacgtgggagctgccacgg
gaccagcttgtgcttggacgcaccctcggctctggggcctttgggcaggtggtggaggcc
acagctcacggcctgagccattcgcaggccacaatgaaagtggcggtcaagatgctgaaa
tccacagcccgcagcagcgagaagcaagccctcatgtcagagctgaagatcatgagtcac
ctcgggccccatctgaacgtggtcaacttgctgggggcctgcacgaaaggaggacccatc
tacatcatcaccgagtactgccagtacggggacctggtggactacctgcaccgcaacaag
cataccttcctgcagcgtggctccgacaagcgccgcccgcccggcgccgagctctacagc
aacgccctgcccggcgggctcccgctgcccagccacatgtctctgcccggggagagcgac
ggtggctacatggacatgagcaaggatgagtcggtggactacgtgcccatgctggacatg
aaaggaggcgtcaaatatgcagacatcgagtcctccagctacatggctccttatgacaac
tatgttcccaccgctcccgagaggacctgtcgggtaactctgatcaacgagtccccagtg
cttagctacacagatctcgtgggcttcagctaccaggtggccaatggcatggagttcctg
gcctccaagaactgtgtccaccgagatctggcagccagaaatgtgctcatctgtgagggc
aagctggtcaagatttgtgacttcggcctggctcgtgacatcatgcgagactcaaactat
atctccaaaggcagcaccttcctgcctctgaagtggatggctcctgagagcatcttcaac
agcctctataccaccctgagcgacgtgtggtccttcgggatcctactctgggagatcttc
accctgggtggcaccccttacccagagctacccatgaatgagcagttctataatgccatc
aagcggggataccgcatggcccagcctgcccacgcctccgatgagatttatgagatcatg
cagaagtgctgggaagagaagtttgagatccggcctcctttctcccagctggtgctgctt
ctcgagaggctgctgggcgaggggtacaaaaagaagtaccagcaggtggatgaggagttt
ctgaggagcgaccacccagccgtccttcggtcccaagcccgcttgcctggcttccatggc
ctccgatcccccctggacaccagctctgtgctctacacggctgtgcagcccaacgagggt
gacaacgactatatcatccccctgcctgaccccaaacctgaagttgctgatgagggccca
ctggagagttctcccagccttgccagctccaccctgaacgaagcgaacacgtcctctacc
atctcctgtgacagccccctggagccccaagaggagcccgaaccccaggtggagccggag
ctggagccaccactggactcgagctgccctgggcatcgggctgaggcagaagacagcttc
ctgtag

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