Mirounga leonina (Southern elephant seal): 118007879
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Entry
118007879 CDS
T07472
Symbol
EIF2AK3
Name
(RefSeq) eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1
KO
K08860
eukaryotic translation initiation factor 2-alpha kinase 3 [EC:
2.7.11.1
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx04137
Mitophagy - animal
mlx04140
Autophagy - animal
mlx04141
Protein processing in endoplasmic reticulum
mlx04210
Apoptosis
mlx04932
Non-alcoholic fatty liver disease
mlx05010
Alzheimer disease
mlx05012
Parkinson disease
mlx05014
Amyotrophic lateral sclerosis
mlx05020
Prion disease
mlx05022
Pathways of neurodegeneration - multiple diseases
mlx05160
Hepatitis C
mlx05162
Measles
mlx05168
Herpes simplex virus 1 infection
mlx05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
118007879 (EIF2AK3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
118007879 (EIF2AK3)
04137 Mitophagy - animal
118007879 (EIF2AK3)
09143 Cell growth and death
04210 Apoptosis
118007879 (EIF2AK3)
09160 Human Diseases
09172 Infectious disease: viral
05160 Hepatitis C
118007879 (EIF2AK3)
05162 Measles
118007879 (EIF2AK3)
05168 Herpes simplex virus 1 infection
118007879 (EIF2AK3)
09164 Neurodegenerative disease
05010 Alzheimer disease
118007879 (EIF2AK3)
05012 Parkinson disease
118007879 (EIF2AK3)
05014 Amyotrophic lateral sclerosis
118007879 (EIF2AK3)
05020 Prion disease
118007879 (EIF2AK3)
05022 Pathways of neurodegeneration - multiple diseases
118007879 (EIF2AK3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
118007879 (EIF2AK3)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
118007879 (EIF2AK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mlx01001
]
118007879 (EIF2AK3)
Enzymes [BR:
mlx01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
118007879 (EIF2AK3)
Protein kinases [BR:
mlx01001
]
Serine/threonine kinases: Other
PEK family [OT]
118007879 (EIF2AK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PQQ_2
Kinase-like
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
118007879
NCBI-ProteinID:
XP_034856988
LinkDB
All DBs
Position
Unknown
AA seq
1113 aa
AA seq
DB search
MERATRPGPLARALLLLLLLGLAAGTVAAGRAPDLPAPKAEAVFGLGAAAAPTSAARVPA
AGAVATAEVTVEDAEAVPAAATEQEPRDPEPDDEAELRPRGRSLVIISTLDGRIAALDPE
NHGKKQWDLDVGSGSLVSSSLSKPEVFGNKMIIPSLDGDLFQWDRDRESMETVPFTVESL
LESSYKFGDDVVLVGGKSLTTYGLSAYSGKVRYICSALGCRQWDNDDMEQEDILLLQRSQ
KTVRAVGPRSGNEKWNFSVGHFELRYIPDMETRAGFIESTLKPRGSKEGSKIISDVEEQE
AAMMDTVIKVSVADWKVMAFSKKGGHLEWEYQFCTPIASAWLVKDGKVIPISLFDDTSYA
SNNEVLEDEEDIVEAARGATENSVYLGMYRGQLYLQSSVRISEKFPTSPKALESVNNEHA
IMPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPYDNGYYL
PYYKRERSKRSTQITVRFLENPSYSKNIRKKDPVLLLHWWKEIVGTILFCIIATTFIVRR
LFHPHPHRQRKESETQCQTESKYDSVSGEAKDSSWNDIINSGYVSRYLTDFEPVQCMGRG
GFGVVFEARNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLDHPGIVRYFNAWLEAP
PEKWQEKMDEIWLKDESTDWPLSSPSPMDAPSVKIRRMDPFSTKEHIEIIAPSSQRRSFS
VGISCGQMSSSESQFSPLEFSGTDRGDTSESMDAACNLQDSCLTECDVEDGTMDGNDEGH
SFELCPSGASLYERSRERTSSSIVFEDSGCDNASSKEELRTKRLHIGNHCANKLTAFKHS
SNKSSSKPTFSVSPPRPTTLSLDLTKNTAEKLQPSSPKVYLYIQMQLCRKENLKDWMNSR
CTIEERERSVCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTVDDVVKVGDFGLVTEMD
QDEEEQMVLTPMPAYARHTGQVGTKLYMSPEQIHGNNYSHKVDIFSLGLILFELLYPFGT
QMERVRILTDVRNLKFPPLFTQKYPREYVMVQDMLSPSPMERPEATTIIENAVFEDLGLP
GKTVLRQRSRSMSSSGTKHSRHSSNSWSPLPSS
NT seq
3342 nt
NT seq
+upstream
nt +downstream
nt
atggagcgcgccacccgcccggggccgctcgcgcgggcgctgctgctgctgctgctgctg
ggactggcggcgggcacggtggccgcggggcgagccccggacctccccgcgccgaaggcg
gaggcggtgtttggcctgggcgcagcggccgctcccacttctgcagcgcgggtgccggcg
gccggggccgtggctacggccgaagtgaccgtggaggacgccgaagctgtgccggcggcc
gctacggagcaggagccgcgggacccggaacccgacgacgaggccgagctacggccgcgc
ggcagatcattagtgattatcagcactttagatgggcgaattgctgccttggatcctgag
aatcatggtaaaaaacagtgggatttggacgtgggatccggttccttggtttcatccagc
ctcagcaaaccagaggtatttgggaataagatgatcatcccttctctggatggagacctc
ttccagtgggaccgggaccgtgagagcatggaaacagttccttttacagttgaatcactt
ctcgaatcttcttataaatttggagatgatgttgttttggttggaggaaagtctctcaca
acatatggactcagtgcatacagtggaaaggtgaggtacatctgttcagctttgggttgt
cgccaatgggataatgatgatatggaacaagaagacatcctgcttctgcaacgctcgcag
aaaactgttagagctgtcggacctcgcagtggcaacgagaagtggaatttcagtgttggc
cactttgaacttcggtatattccagacatggaaactagagccggatttattgaaagcacc
ttaaagcccagagggagcaaagaagggtctaaaattatttcagatgtggaagaacaggaa
gccgccatgatggacacagtgataaaggtctcagttgctgactggaaggttatggcgttt
agcaagaagggaggacatctggaatgggaataccagttttgtactcccattgcatctgct
tggttggttaaggatggaaaagtcattcccatcagtctttttgatgatacaagttatgca
tctaacaatgaagtgttagaagatgaagaagacattgtagaagctgctcgaggagccacg
gaaaatagcgtttacctaggaatgtacagaggtcagctgtatctgcagtcatcagtcaga
atttcagaaaagtttcctacaagtcccaaggccttggaatctgtcaataatgagcatgca
attatgcctttgccaacaatcaaatggaaacccttaattcattctccttctagaactcct
gtcttggtagggtctgatgaatttgacaaatgtcttagtaatgataagttttctcatgaa
gagtacagtaatggcgccctttccatcttgcaatacccatatgataatggttattatcta
ccatactacaagagggagaggagcaaacggagcacacagatcacagtccgatttctcgag
aacccaagttacagcaagaacattcgcaaaaaggatcctgttctcctcttacactggtgg
aaagaaatagttggaactattctgttttgtatcatagcaacaacttttattgtgcgtaga
cttttccatcctcatcctcacagacaaaggaaggaatctgaaactcagtgtcaaactgaa
agtaaatatgattctgtcagtggagaagctaaggacagtagctggaatgacattataaat
tctggatatgtatcacgctatctaacagattttgaaccagttcagtgcatgggtcgtggc
gggtttggagtcgtctttgaagccagaaacaaagtagatgactgcaattatgctatcaag
agaattcgcctccccaacagggagttggctcgggaaaaggtaatgcgagaagttaaagcc
ttagccaagcttgaccacccagggattgttagatatttcaatgcttggttggaagcacca
ccagagaagtggcaagaaaaaatggatgaaatttggctgaaagatgaaagcacagactgg
ccactcagttctcctagtccaatggatgcaccatcggttaaaatacgcagaatggatcct
ttctctacaaaggaacatattgaaatcatagctccttcttcacaaaggaggtctttttca
gtagggatttcctgtggccagatgagttcatctgagagtcagttctctccactggaattt
tcaggaacggaccgtggagataccagtgagtccatggatgcagcatgcaacctccaagac
agttgtcttacggaatgcgatgtggaagatggtactatggatggcaatgatgaggggcac
tcctttgaactttgtccttctggagcttctctttatgaaaggtcaagggagagaacatcc
tcttctatagtatttgaagattctggctgtgataacgcgtccagtaaagaagagctcaga
acgaagcgactgcatattggcaaccattgtgctaataaactaactgctttcaagcattcc
agtaacaaatcttcttctaaacctactttctctgtttctcctccaagaccgaccacttta
agtttagatctcactaaaaacactgcagaaaaactccagcccagttccccaaaggtatat
ctttacattcagatgcagctctgcagaaaggaaaacctcaaagactggatgaacagccga
tgtaccatagaggagagagagaggagtgtgtgtctgcacatcttcctgcagatcgcagag
gccgtagagtttctgcacagtaaagggctcatgcacagggacctcaagccttccaacata
ttctttacagtggacgatgtggtcaaggttggagactttggattagtgactgaaatggac
caggatgaggaagagcagatggttctgaccccaatgccagcatatgccagacacacagga
caagtggggaccaagctgtatatgagcccagagcagattcatggaaacaactactctcat
aaagtggacatcttttctctaggcctcattctgtttgaattgctgtacccattcggcact
cagatggagagagtcaggatcttaactgatgtaagaaatctcaaatttccaccactattt
actcagaaatatcctcgtgagtatgtgatggttcaagacatgctctctccatcccccatg
gaacggcctgaggccaccaccatcattgaaaatgctgtatttgaagacttggggcttccc
ggaaaaacagtactcagacagaggtctcgctccatgagttcatcgggaacaaaacattca
agacattccagcaactcctggagccctttgccaagcagttag
DBGET
integrated database retrieval system
