Mirounga leonina (Southern elephant seal): 118007936
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Entry
118007936 CDS
T07472
Symbol
HK2
Name
(RefSeq) hexokinase-2 isoform X1
KO
K00844
hexokinase [EC:
2.7.1.1
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx00010
Glycolysis / Gluconeogenesis
mlx00051
Fructose and mannose metabolism
mlx00052
Galactose metabolism
mlx00500
Starch and sucrose metabolism
mlx00520
Amino sugar and nucleotide sugar metabolism
mlx00524
Neomycin, kanamycin and gentamicin biosynthesis
mlx01100
Metabolic pathways
mlx01200
Carbon metabolism
mlx01250
Biosynthesis of nucleotide sugars
mlx04066
HIF-1 signaling pathway
mlx04910
Insulin signaling pathway
mlx04930
Type II diabetes mellitus
mlx04973
Carbohydrate digestion and absorption
mlx05230
Central carbon metabolism in cancer
Module
mlx_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
mlx_M00549
UDP-Glc biosynthesis, Glc => UDP-Glc
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
118007936 (HK2)
00051 Fructose and mannose metabolism
118007936 (HK2)
00052 Galactose metabolism
118007936 (HK2)
00500 Starch and sucrose metabolism
118007936 (HK2)
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
118007936 (HK2)
09110 Biosynthesis of other secondary metabolites
00524 Neomycin, kanamycin and gentamicin biosynthesis
118007936 (HK2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
118007936 (HK2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
118007936 (HK2)
09154 Digestive system
04973 Carbohydrate digestion and absorption
118007936 (HK2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
118007936 (HK2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
118007936 (HK2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mlx04131
]
118007936 (HK2)
Enzymes [BR:
mlx01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.1 hexokinase
118007936 (HK2)
Membrane trafficking [BR:
mlx04131
]
Autophagy
Mitophagy
Other mitophagy associated proteins
118007936 (HK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Hexokinase_2
Hexokinase_1
Motif
Other DBs
NCBI-GeneID:
118007936
NCBI-ProteinID:
XP_034857102
LinkDB
All DBs
Position
Unknown
AA seq
917 aa
AA seq
DB search
MIASHLLAYFFTELNHDQVQKVDQYLYHMRLSDENLLEISKRFRKEMEKGLGVTTHPTAS
VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLRVRVTDNGLQKVEMENQIYAIPEDLMR
GSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCVQTKLDESFLVSWTKGFKSSGV
EGKDVVTLIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGSNACYME
EMRHIDMVEGDEGRMCINMEWGAFGDDGILDDFRTEFDQEIDMGSLNPGKQLFEKMISGM
YMGELVRLILVKMAKEELLFGGKLSPGLLATGQFETKDVSDIEGEKDGTWKAREVLVRLG
IDPTQEDCVATHRICQIVSTRSASLCAATLAAVLRRIKENKGEERLRSTIGVDGSVYKKH
PHFAKRLHKTVRRLVPDCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQNTLESLKLS
REQLLEVKRRMNVEMERGLSKETHAIAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRV
LLVRVRNGKRRGVEMHNKIYSIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGF
TFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVG
TMMTCGYEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGRMCVNMEWGAFGDNGCLDD
FRTEFDVAVDELSLNPGRQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRG
IFETKFLSQIESDCLALLQVRAILHHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAA
VVDKIRENRGLDTLKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCDVSFLESEDGSGKG
AALITAVACRIREAGQR
NT seq
2754 nt
NT seq
+upstream
nt +downstream
nt
atgatcgcctcgcatctgctcgcctatttcttcacggagctcaaccatgaccaagtgcag
aaggttgaccagtatctctaccacatgcgtctttctgatgagaaccttctggagatctct
aagcggttccgcaaggagatggagaaggggcttggagtcaccacccaccccactgcttca
gtgaaaatgctgcccaccttcgtgaggtctactccggatgggacagaacatggagagttc
ctggctctggacctcggagggacaaacttccgtgtacttcgggtaagagtaacagacaat
gggctccagaaggtcgagatggagaaccagatctatgccatccccgaggacctcatgaga
ggcagcggcacccagctgtttgaccacattgcagaatgcctggctaacttcatggataag
ctacaaatcaaagacaagaagctccccttgggttttactttctcattcccctgcgtccaa
acaaaactagatgagagtttcctggtctcctggaccaaggggttcaagtccagtggtgta
gaagggaaagacgtggttactctgatccggaaggccatccagaggagaggggactttgat
attgatatcgtggccgtggtgaacgacacagttgggaccatgatgacctgtggttatgat
gaccagaattgcgagattggtctcattgtaggcacgggcagcaacgcctgctacatggaa
gagatgcgccacattgacatggtggagggcgacgaggggcggatgtgtatcaacatggag
tggggggccttcggggacgatggcatactcgatgacttccgcactgagtttgatcaggag
atcgacatgggctccctgaaccccgggaaacaactattcgagaagatgatcagtgggatg
tacatgggagaactggtgaggcttatcctggtgaagatggccaaggaagagctgcttttc
ggggggaagctcagcccagggctccttgccactggccagtttgagaccaaagatgtttca
gatatcgaaggggagaaggacggcacctggaaggcacgtgaggtgctggtgcggctgggc
atagacccgacacaggaggactgcgtggccactcaccggatctgccagatcgtgtctacg
cgctcagccagcctgtgtgcggccaccctggcggccgtgctgcggcgcatcaaggagaac
aagggcgaggagcggctgcgctccaccattggggtggacggctctgtctacaagaagcac
ccacactttgccaagcgtcttcacaagacggtacggcgcctggtgcccgactgtgacgtc
cgcttcctgcgttctgaggatggcagcggcaagggggcagccatggtgacggcggtggcc
taccggctagctgaccaacaccgagcccgccagaacaccctggagtctctgaagctgagc
cgcgagcagctgctggaggtcaagaggaggatgaacgtggagatggagcgaggtctgagc
aaggagactcacgccattgcccccgtcaagatgctgcccacctacgtgtgtgccacgcct
gatggcacagagaaaggtgacttcctggccttggaccttgggggtaccaacttccgggtc
ctgctggtgcgagtgaggaatggaaagcggcgtggagtagagatgcacaacaagatctac
tctatcccgcaggaggtcatgcacggcacgggggacgagctctttgaccacatcgtccag
tgcatcgccgacttccttgagtacatgggcatgaagggcgtgtccctgcctctgggtttc
accttctccttcccctgccagcagaacagcctggatgagagcatcctcctcaagtggact
aaaggcttcaaggcatcgggctgtgagggagaggacgtggtcacgctgctgaaggaggcc
atccaccggcgagaggagtttgacctggacgtggtcgctgtggtgaatgacacagtcggg
actatgatgacctgtggctatgaagaccctcactgtgaagtcggcctcatcgttggcacg
ggcagcaacgcctgctacatggaggagatgcggaacgtggagctggtagagggggaggag
ggccggatgtgtgtcaacatggagtggggggccttcggggacaacggatgcctcgacgac
ttccgcacggaatttgatgtggctgtggatgagctttccctcaaccctggcagacagagg
ttcgagaaaatgatcagcggcatgtacttgggggagattgtccgtaacatcctcatcgat
ttcaccaagcgtgggctgctcttccgtggccgcatctcagagcggctcaagacaagggga
atctttgaaaccaagttcttgtctcagattgagagtgactgcctggccctgctgcaggtc
cgcgccatcctgcaccacctggggctcgagagcacgtgtgacgatagcatcattgtcaaa
gaggtatgcaccgtggtggcgcggcgggcagcccagctctgtggtgcgggcatggccgcc
gtggtggacaagatccgagagaaccgggggctggacaccctcaaagtgaccgtgggcgtg
gatgggaccctctacaagctacaccctcactttgccaaagtcatgcacgagacggtgaag
gacctggctccgaaatgtgacgtgtccttcctggagtcagaggacggcagcgggaagggg
gcggctctcatcactgctgtggcctgccgcatccgcgaggctggccagcgatag
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