Mirounga leonina (Southern elephant seal): 118011397
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Entry
118011397 CDS
T07472
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx04120
Ubiquitin mediated proteolysis
mlx04144
Endocytosis
mlx04330
Notch signaling pathway
mlx04668
TNF signaling pathway
mlx04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
118011397 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
118011397 (ITCH)
04668 TNF signaling pathway
118011397 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
118011397 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
118011397 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mlx04131
]
118011397 (ITCH)
04121 Ubiquitin system [BR:
mlx04121
]
118011397 (ITCH)
Enzymes [BR:
mlx01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
118011397 (ITCH)
Membrane trafficking [BR:
mlx04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
118011397 (ITCH)
Ubiquitin system [BR:
mlx04121
]
Ubiquitin ligases (E3)
HECT type E3
118011397 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
118011397
NCBI-ProteinID:
XP_034862034
LinkDB
All DBs
Position
Unknown
AA seq
862 aa
AA seq
DB search
MSGSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIFETLKSNNMKLEEVVMTL
QLVGDKEPTETIGDLSVCLDGLQLESEVVTNGETTGSESASQNDDGSRPKDETRTNTNGS
DEPEDAGAGENRKVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNINSNTSEGATSGLIIPLTISGGSGPRPLNSVPQAPLPPGWEQRVDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFTTSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFNPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctggcagtggatcacagcttggttcaatgggtagcctgaccatgaaatcacaactt
cagatcactgtcatttcagcgaaacttaaagaaaataaaaagaattggtttggaccaagt
ccttatgtggaagtcacagtagacggacagtcaaagaagacagaaaaatgcaacaatacg
aacagtcccaaatggaagcaaccccttacagttatcgtcacccctgtgagtaaattacat
tttcgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctgcatta
gatatctttgaaaccttaaagtcaaacaacatgaaacttgaggaagtagttatgacttta
cagcttgtaggtgacaaagagccaacagagacaataggagacttgtcagtttgtcttgat
gggctgcagttagagtctgaagttgttaccaatggtgaaactacaggttcagaaagtgct
tcacagaatgatgatggctccagacccaaggatgaaacaagaacaaacacaaatggatca
gatgagcctgaggatgcaggggctggtgaaaataggaaggtcaatgggaataattctcca
tcactctcaaatggtggttttaaaccttctaggcctccaagaccttcacgaccacctcca
cctaccccacgtagaccagcatctgtcaatggttcaccatctgccacttctgaaagtgat
ggatccagtacaggctctctgccgccaacaaatataaattcaaatacatctgaaggagca
acatctggattaataattcctctgactatatctggaggctcaggccctaggccattaaat
tctgtacctcaggctcccctaccacctggttgggagcagagagtggaccagcatggacga
gtttactatgtagatcatattgaaaaaagaacaacctgggatagaccagaacctctacct
cctggctgggaacggcgggttgacaacatgggacgtatttactatgttgaccatttcaca
agaacaacaacgtggcagaggccaacgttggaatctgtccggaactatgaacagtggcag
ctccaacgtagtcagctgcaaggagcaatgcagcagtttaaccagagatttatttatggg
aatcaagatttgtttactacatcacaaaataaagaatttgatccccttggtcccctgcca
cctggatgggagaagagaacagacagcaatggtagagtatattttgtcaaccacaacact
cgtattacacaatgggaagaccccagaagtcaaggccaattaaatgaaaagcccttacct
gaaggctgggaaatgagattcacagttgatggaattccgtattttgtggaccacaataga
agaacaaccacctatattgatccccgcactggaaaatctgccctagacaatggaccacag
atagcctatgtacgggacttcaaggcaaaagttcagtatttccggttctggtgtcagcaa
ctggccatgccacagcacataaagattacagtgacaagaaagacattatttgaagattcc
tttcagcagataatgagcttcaatccccaagatctgagaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagagtggttctttcttttgtca
cacgaggtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgc
ttgcagattaatcctgcttcttacatcaatccagatcacctgaaatattttcgttttatt
ggcaggtttattgccatggctctgttccatgggaaattcatagacacaggtttttctttg
ccattctataagcgtatattgaacaaaccagttggactcaaggatttagaatctattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggaatgtggtttg
gaaatgtacttctctgtcgataaagaaattttaggtgaaatcaagagtcatgatttgaaa
cctaatggtggaaatattcttgtgacagaagaaaataaagaggaatatatcagaatggta
gctgaatggaggttgtctcgaggtgttgaagaacagacacaagcattctttgagggcttt
aatgaaattcttccccagcagtatttgcaatactttgatgcaaaggagttagaggtcctt
ttatgtggaatgcaagagattgatttgaatgactggcaaagacatgccatctaccgtcat
tacactaggacaagcaaacaaatcatgtggttttggcagtttgttaaagaaattgataat
gagaagagaatgagacttctgcagtttgttactggaacctgccgattgccagttggagga
tttgctgacctcatggggagcaatggaccacaaaaattctgcattgaaaaagttggaaaa
gaaaattggttacccagaagtcatacatgttttaaccgcctggacctgccaccgtacaag
agctatgagcaactgaaagaaaagctgttatttgccattgaagaaacagaaggatttgga
caagagtaa
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