Mirounga leonina (Southern elephant seal): 118015244
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Entry
118015244 CDS
T07472
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx01522
Endocrine resistance
mlx04012
ErbB signaling pathway
mlx04062
Chemokine signaling pathway
mlx04148
Efferocytosis
mlx04151
PI3K-Akt signaling pathway
mlx04360
Axon guidance
mlx04370
VEGF signaling pathway
mlx04510
Focal adhesion
mlx04670
Leukocyte transendothelial migration
mlx04810
Regulation of actin cytoskeleton
mlx04935
Growth hormone synthesis, secretion and action
mlx05100
Bacterial invasion of epithelial cells
mlx05135
Yersinia infection
mlx05146
Amoebiasis
mlx05163
Human cytomegalovirus infection
mlx05165
Human papillomavirus infection
mlx05170
Human immunodeficiency virus 1 infection
mlx05200
Pathways in cancer
mlx05202
Transcriptional misregulation in cancer
mlx05205
Proteoglycans in cancer
mlx05208
Chemical carcinogenesis - reactive oxygen species
mlx05222
Small cell lung cancer
mlx05417
Lipid and atherosclerosis
mlx05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
118015244 (PTK2)
04370 VEGF signaling pathway
118015244 (PTK2)
04151 PI3K-Akt signaling pathway
118015244 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
118015244 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
118015244 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
118015244 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
118015244 (PTK2)
04062 Chemokine signaling pathway
118015244 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
118015244 (PTK2)
09158 Development and regeneration
04360 Axon guidance
118015244 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
118015244 (PTK2)
05202 Transcriptional misregulation in cancer
118015244 (PTK2)
05205 Proteoglycans in cancer
118015244 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
118015244 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
118015244 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
118015244 (PTK2)
05163 Human cytomegalovirus infection
118015244 (PTK2)
05165 Human papillomavirus infection
118015244 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
118015244 (PTK2)
05100 Bacterial invasion of epithelial cells
118015244 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
118015244 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
118015244 (PTK2)
05418 Fluid shear stress and atherosclerosis
118015244 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
118015244 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mlx01001
]
118015244 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
mlx01009
]
118015244 (PTK2)
Enzymes [BR:
mlx01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
118015244 (PTK2)
Protein kinases [BR:
mlx01001
]
Non-receptor tyrosine kinases
FAK family
118015244 (PTK2)
Protein phosphatases and associated proteins [BR:
mlx01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
118015244 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_C_FAK1
FERM_N_2
FERM_M
Kinase-like
Haspin_kinase
FERM_F2
ABC1
Motif
Other DBs
NCBI-GeneID:
118015244
NCBI-ProteinID:
XP_034867894
LinkDB
All DBs
Position
Unknown
AA seq
1099 aa
AA seq
DB search
MLLELAGQGALRPAGAVCMEKSGCSPFPMCWAKEYDRYIASSKIMAAAYLDPNLNHTPNS
STKPHLGTGVERSPGAMERVLKVFHYFENSSEPATWASIIRHGDATDVRGIIQKIVDSHK
VKHVACYGFRLSHLRSEEVHWLHLDMGVSNVREKYELAHPPEEWKYELRIRYLPKGFLNQ
FTEDKPTLNFFYQQVKSDYMSEIADRVDQDIALKLGCLEIRRSYWEMRGNALEKKSNYEV
LEKDVGLKRFFPRSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE
CFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFNQVQTIQYSNSEDKDRKGML
QLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFIIRPQKEGERALPSIPKL
ANSEKQGMRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDV
HQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVW
IIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSS
NDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEIL
MHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQL
STILEEEKVQQEERMRMESRRQVTVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHM
VQTNHYQVSGYPGSHGITAMAGSIYPGQATLLDQTDSWNHRPQEISMWQPNVEDSAALDL
RGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRPSRGSMDREDGSLQGPTG
NQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPGDSYNEGVKPWRLQPQEISPPP
TANLDRSNDRVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETLP
VLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKN
LLDVIDQARLRMLGPTRPH
NT seq
3300 nt
NT seq
+upstream
nt +downstream
nt
atgttgctggaactggcgggccaaggggccctgagaccagcaggtgccgtctgtatggag
aagagcggctgtagtccatttccaatgtgttgggctaaagagtatgacagatacatagca
tctagcaaaataatggcagctgcttaccttgacccaaacttgaatcacacaccgaattcg
agtaccaagcctcatctgggtactggagtggaacgttcccctggggcaatggagcgagtg
ttgaaggtctttcattattttgaaaacagcagtgagccagccacttgggccagtattatc
aggcatggagatgctactgatgtcaggggcatcattcagaagatagtggacagtcacaaa
gtaaagcacgtggcctgctatggatttcgcctcagtcacctgcggtcagaggaggttcac
tggctccatttggatatgggtgtctccaatgtgagggagaagtatgaacttgcacaccca
ccagaggagtggaaatatgaattgagaattcgttatttgccaaaaggatttctaaaccag
tttactgaagacaagccaactctgaatttcttctatcaacaggtgaagagcgactacatg
tccgagatagctgaccgcgtggaccaggacattgctttgaagctgggctgtctagagata
cggcgctcgtactgggagatgcgaggcaacgcgctagagaagaagtccaactatgaagtg
ttagaaaaagatgttggtttgaagcgattttttcctaggagtttactggattctgtcaag
gccaaaacactaagaaagctgatccaacagacatttagacagtttgccaaccttaacaga
gaagaaagtattctgaagttctttgagatcctctccccggtgtacagatttgataaagaa
tgcttcaagtgtgctctgggttcaagctggattatttcggtggaactggcaattggccca
gaagaaggaatcagttacctcacggacaagggctgcaaccccacacatctggccgacttc
aatcaagtgcagaccattcagtattcgaacagcgaagacaaggaccggaaagggatgcta
cagctgaaaattgccggtgcccccgagcctctgacagtgacagcgccatccctaaccatc
gccgagaatatggctgacttgatagatgggtactgccggctggtgaacggggccacacag
tcttttatcatcagaccccagaaagaaggtgaacgggcgttgccatcaataccaaagctg
gccaacagcgagaagcaaggcatgcggacacacgcggtctccgtgtcagaaacagatgat
tatgctgagattatagacgaagaagacacctacaccatgccctcaaccagggattatgag
attcagagagaaagaatcgagcttggacggtgcattggggaaggccagtttggagacgtc
catcaaggcatctatatgagcccagagaatccagctttggcggttgcaattaaaacatgt
aaaaactgtacttcggacagcgtgagagagaaattccttcaagaagccttaacaatgcgt
cagtttgaccaccctcacattgtgaagctgattggtgtcatcacggagaaccctgtctgg
ataatcatggagctgtgcacgctgggagagctgaggtcatttctgcaagtgaggaagtac
agtttggacctagcgtctttgatcctatatgcctatcagcttagtacagctctcgcgtat
ctggagagcaaaagatttgtgcacagggacattgctgctcggaatgttctggtgtcctct
aatgattgcgtaaaactaggagactttggattatcccgatatatggaagacagtacttat
tacaaagcttccaaaggaaaattgccaattaagtggatggctccagagtccatcaatttt
cgacgttttacctcagctagtgatgtatggatgtttggtgtatgtatgtgggagatactg
atgcatggtgtgaagccttttcaaggagtgaagaacaatgatgtgatcggtcgaattgag
aatggggagagattaccaatgcctccaaattgccctcctaccctctacagccttatgacg
aaatgctgggcctatgaccccagcaggcggccccggttcactgagctcaaagctcagctc
agcacaatcctggaggaggagaaggttcagcaagaagaacggatgaggatggagtccaga
agacaggtcacagtgtcctgggactccggagggtccgacgaagcgccacccaagcccagc
agacccggttacccgagtccaaggtccagtgaaggattttatcccagcccacagcacatg
gtacaaaccaatcattaccaggtctctggctatcctggttcacatgggatcacggccatg
gctggcagcatctacccgggtcaggcaactcttttggaccagacggattcctggaatcat
agaccgcaggagatatcaatgtggcagcccaacgtggaggactccgctgcgctggacctg
cgtgggatcgggcaggtgttgccaacccacctgatggaagagcggctgatccggcagcag
caggagatggaagaagatcagcgctggctagaaaaagaggagagattcctgaaacctgac
gtgcggccctctcgaggcagtatggacagggaggatggaagtctccagggcccgactgga
aaccaacacatatatcagcctgtggggaaaccagatcctgcagccccgccaaagaaaccg
ccgcggcctggggcccccggtcacctgggcagcctcgccagcctcagcagccccggggac
agctacaacgagggcgtcaagccatggaggcttcagccccaggaaatcagccccccgccc
actgccaacctggaccggtccaacgacagggtgtacgagaatgtgacgggcctggtgaag
gctgtcatcgagatgtccagcaagatccagccagccccgccagaggagtacgttcccatg
gtgaaggaagtcggcctggccctgcggacgttactggccactgtggacgagaccctcccg
gtcctgccagccagcactcaccgagagattgagatggcccagaagctgttgaactccgac
ctgggtgagctcatcaacaagatgaaactggcccagcagtacgtcatgaccagtctccag
caggagtacaaaaagcaaatgctgaccgcggctcacgccctggccgtggatgccaaaaac
ttactcgacgtcattgaccaagcgagactgcggatgctcggaccgacgaggccgcattga
DBGET
integrated database retrieval system
