KEGG   Mirounga leonina (Southern elephant seal): 118015773
Entry
118015773         CDS       T07472                                 
Symbol
TRAF6
Name
(RefSeq) TNF receptor-associated factor 6 isoform X1
  KO
K03175  TNF receptor-associated factor 6 [EC:2.3.2.27]
Organism
mlx  Mirounga leonina (Southern elephant seal)
Pathway
mlx04010  MAPK signaling pathway
mlx04064  NF-kappa B signaling pathway
mlx04120  Ubiquitin mediated proteolysis
mlx04140  Autophagy - animal
mlx04144  Endocytosis
mlx04380  Osteoclast differentiation
mlx04620  Toll-like receptor signaling pathway
mlx04621  NOD-like receptor signaling pathway
mlx04622  RIG-I-like receptor signaling pathway
mlx04657  IL-17 signaling pathway
mlx04722  Neurotrophin signaling pathway
mlx04936  Alcoholic liver disease
mlx05132  Salmonella infection
mlx05133  Pertussis
mlx05135  Yersinia infection
mlx05140  Leishmaniasis
mlx05142  Chagas disease
mlx05145  Toxoplasmosis
mlx05152  Tuberculosis
mlx05160  Hepatitis C
mlx05161  Hepatitis B
mlx05162  Measles
mlx05168  Herpes simplex virus 1 infection
mlx05169  Epstein-Barr virus infection
mlx05170  Human immunodeficiency virus 1 infection
mlx05171  Coronavirus disease - COVID-19
mlx05200  Pathways in cancer
mlx05222  Small cell lung cancer
mlx05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mlx05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mlx00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    118015773 (TRAF6)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118015773 (TRAF6)
   04064 NF-kappa B signaling pathway
    118015773 (TRAF6)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    118015773 (TRAF6)
   04140 Autophagy - animal
    118015773 (TRAF6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    118015773 (TRAF6)
   04621 NOD-like receptor signaling pathway
    118015773 (TRAF6)
   04622 RIG-I-like receptor signaling pathway
    118015773 (TRAF6)
   04657 IL-17 signaling pathway
    118015773 (TRAF6)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    118015773 (TRAF6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    118015773 (TRAF6)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118015773 (TRAF6)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    118015773 (TRAF6)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    118015773 (TRAF6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    118015773 (TRAF6)
   05161 Hepatitis B
    118015773 (TRAF6)
   05160 Hepatitis C
    118015773 (TRAF6)
   05171 Coronavirus disease - COVID-19
    118015773 (TRAF6)
   05162 Measles
    118015773 (TRAF6)
   05168 Herpes simplex virus 1 infection
    118015773 (TRAF6)
   05169 Epstein-Barr virus infection
    118015773 (TRAF6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    118015773 (TRAF6)
   05135 Yersinia infection
    118015773 (TRAF6)
   05133 Pertussis
    118015773 (TRAF6)
   05152 Tuberculosis
    118015773 (TRAF6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    118015773 (TRAF6)
   05140 Leishmaniasis
    118015773 (TRAF6)
   05142 Chagas disease
    118015773 (TRAF6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    118015773 (TRAF6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    118015773 (TRAF6)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mlx04131]
    118015773 (TRAF6)
   04121 Ubiquitin system [BR:mlx04121]
    118015773 (TRAF6)
Enzymes [BR:mlx01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     118015773 (TRAF6)
Membrane trafficking [BR:mlx04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    118015773 (TRAF6)
Ubiquitin system [BR:mlx04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   TRAF proteins
    118015773 (TRAF6)
SSDB
Motif
Pfam: TRAF-mep_MATH MATH_2 zf-TRAF TRAF6_Z2 zf-C3HC4_2 zf-C3HC4 zf-RING_UBOX zf-RING_2 zf-C3HC4_3 zf-C3HC4_4 zf-TRAF_2 zf-RING_5 Sina_ZnF SlyX TRAF3_RING RING_XB3-XBAT31 DUF16 U-box zf-RING_11 DUF4455 DUF3450 Spc29 PspA_IM30 DUF7310 Med21 DUF6271 Laminin_II UPF0242 ATG16 DUF1664 TMF_DNA_bd
Other DBs
NCBI-GeneID: 118015773
NCBI-ProteinID: XP_034868481
LinkDB
Position
Unknown
AA seq 561 aa
MCVKAFFPHYFYRAVDNHITMSLLNCENSCGSGQSQGDCCGAMAGPCSAAAKDDSVGGTA
GPGNLSSSFMEEIQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRD
AGHKCPVDNEILLENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQVHCEFALM
NCPQCQRPFQKCQLNIHILKECPRRQVSCVNCAALMAFEDKEIHDQNCPLANVICEYCNT
MLIREQMPNHYDLDCPTAPIPCTFSTFGCHVKMQRNHLARHLQENTQSHMRMLAQAVQGL
SLALAPVPQRDMAPYDSSSVSRVSTPCHPEVHNFQETIQQLEGRLVRQDHQIRELTAKME
TQSMYVNELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNFGMHLKSQEEEKPVVIHSPGFY
TGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLAILDQSEAP
VRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLDALRQRTFIKDDTLLVRCEVST
RFDMGSLRREGFQPRSTDSGT
NT seq 1686 nt   +upstreamnt  +downstreamnt
atgtgtgtgaaggcattttttcctcactatttctacagagcagttgataatcacattact
atgagtctgctaaactgtgagaacagctgtggatccggccagtcccagggtgactgctgt
ggtgctatggccggcccgtgtagcgctgcagcaaaagatgacagtgtgggtggaaccgcc
ggcccggggaacctgtccagctcctttatggaagagatccaggggtatgatgtggagttt
gacccacccctggaaagcaagtatgaatgccccatctgcttgatggcgttaagggaagcg
gtgcaaacaccatgtggccacaggttctgcaaagcttgcatcatcaaatcaataagggat
gctggtcacaaatgtccagttgacaatgaaatattgctggaaaatcaactatttcctgac
aattttgcaaaacgagagattctttctttgatggtgaagtgtccaaatgaaggttgtttg
cacaagatggaactgaggcatcttgaggatcaccaagtacattgtgagtttgctctcatg
aattgtccccagtgccaacgtcccttccaaaaatgccagcttaatattcacattcttaag
gagtgcccgaggagacaggtttcttgcgtgaactgtgctgcgttgatggcatttgaagat
aaagagatccatgaccagaactgtcctttggcaaatgtcatctgtgaatactgcaatact
atgctcatcagagaacagatgcctaatcactatgatctagactgtccgacagccccaatt
ccatgcacattcagtacttttggttgccatgtaaagatgcagaggaatcacttggcacgc
cacctacaagagaatacccagtcgcacatgagaatgttggctcaggccgttcagggttta
agccttgctttagctcctgtacctcagcgtgatatggcgccatacgattcttcctctgtg
tcccgggtctccactccatgtcaccccgaggtccataatttccaagaaaccattcagcag
ttagagggtcgccttgtaagacaagaccatcaaatccgagagctaactgctaaaatggaa
actcagagcatgtatgtaaatgagctcaaacgaaccattcgaacccttgaagacaaagtt
gctgaaatagaagcgcagcagtgcaacgggatctacatctggaagattggcaactttggg
atgcatttgaaatctcaggaagaggagaaacctgttgtcattcacagccctggattctac
acgggcaaacctggctacaaactgtgcatgcgcctgcacctccagttaccaactgctcag
cgctgtgctaattatatatccctctttgtccacacaatgcagggagagtatgacagccac
ctgccttggcccttccagggtacaatacgccttgcaattcttgatcagtctgaagcgcct
gtaaggcagaaccacgaagagatcatggatgccaaaccagagctgcttgccttccagaga
cccacaatcccacggaacccaaaaggttttggctatgtgacttttatgcacctggatgcc
ctaagacaaagaaccttcattaaggatgatactttgttagtacgctgtgaggtctctacc
cgctttgacatgggcagtctccggagggagggttttcagccacgaagtactgattcaggg
acatag

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