Mirounga leonina (Southern elephant seal): 118017078
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Entry
118017078 CDS
T07472
Symbol
HK3
Name
(RefSeq) hexokinase-3 isoform X1
KO
K00844
hexokinase [EC:
2.7.1.1
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx00010
Glycolysis / Gluconeogenesis
mlx00051
Fructose and mannose metabolism
mlx00052
Galactose metabolism
mlx00500
Starch and sucrose metabolism
mlx00520
Amino sugar and nucleotide sugar metabolism
mlx00524
Neomycin, kanamycin and gentamicin biosynthesis
mlx01100
Metabolic pathways
mlx01200
Carbon metabolism
mlx01250
Biosynthesis of nucleotide sugars
mlx04066
HIF-1 signaling pathway
mlx04910
Insulin signaling pathway
mlx04930
Type II diabetes mellitus
mlx04973
Carbohydrate digestion and absorption
mlx05230
Central carbon metabolism in cancer
Module
mlx_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
mlx_M00549
UDP-Glc biosynthesis, Glc => UDP-Glc
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
118017078 (HK3)
00051 Fructose and mannose metabolism
118017078 (HK3)
00052 Galactose metabolism
118017078 (HK3)
00500 Starch and sucrose metabolism
118017078 (HK3)
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
118017078 (HK3)
09110 Biosynthesis of other secondary metabolites
00524 Neomycin, kanamycin and gentamicin biosynthesis
118017078 (HK3)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
118017078 (HK3)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
118017078 (HK3)
09154 Digestive system
04973 Carbohydrate digestion and absorption
118017078 (HK3)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
118017078 (HK3)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
118017078 (HK3)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mlx04131
]
118017078 (HK3)
Enzymes [BR:
mlx01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.1 hexokinase
118017078 (HK3)
Membrane trafficking [BR:
mlx04131
]
Autophagy
Mitophagy
Other mitophagy associated proteins
118017078 (HK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Hexokinase_2
Hexokinase_1
Motif
Other DBs
NCBI-GeneID:
118017078
NCBI-ProteinID:
XP_034870921
LinkDB
All DBs
Position
Unknown
AA seq
984 aa
AA seq
DB search
MPHIEREELTPEESDQLLLLPGGHPPLWNHMDSIGSVRLRQREGAPGCSQEDLPCPSDSS
ELVLECLQQFKVTETQLRQIQASLLGSMEQALGGQASPASAVQMLPTYVGSTPHGTEQGD
FVVLELGATGASLRVLWVTLLGIEGHRMEPRSQEFVIPPEVMLGPGQQLFDFAAHCLSEF
LDALPVDKEGLQLGFSFSFPCHQTGLDRVRQSGHGDSRWRSCSPMKAVGGMTQLFCPQST
LISWTKGFRCSGVEGHDVVQLLRDAIKRQGAYSIDVVAVVNDTVGTMMGCEPGVGPCEVG
LVVDTGTNACYMEEARHVAVLDEDRGRVCISVEWGSFSDDGVLGPVLTTFDHALDRESLN
PGAQRFEKMIGGLYLGELVRLVLAHLAQRGVLFGGCTSPALLSRGSILLEHVAEMKDPLA
GAARVHAILRDMGLSMGASDAELVQYVCAAVFTRAARLCAAALAAVLARLQHSREQQVLQ
IAVATGGRVFERYPSFLSILQETVMLLAPECDVSFIPSVDGGGRGVAMVTAVAARLAAHR
RLLEETLAPFRLDHEQLAAVRAQMREAMVKGLRGESSSLRMLPTYVRATPDGTERGDFLA
LDLGGTNFRVLLVRVTAGGVKITSQVYSIPEYVAQGSGQQLFDHIVDCIVDFQQKQGLSG
QSLPLGFTFSFPCRQLGLDQGILLNWTKGFNASDCEGQDIVCLLREAIGRREAVELNVVA
IVNDTVGTMMSCGYEDPRCEVGLIVGTGTNACYMEELQNVAAVPGDSGHMCINMEWGAFG
DDGSLDLLRTCFDANVDQASINPGKQSFEKMISGMYLGEIVRHILLHLTSLGVLFRGQQT
QGLQTRDIFKTKFLSEIESDSLALRQVRTILEDLGLSLTSDDALMVLEVCQAVSQRAAQL
CGAGVAAVVEKIRENRGLEELTVSVGVDGTLYKLHPHFSGLVAATVRELAPRCVVTFLQS
EDGSGKGAALVTAVACRLAQMAHV
NT seq
2955 nt
NT seq
+upstream
nt +downstream
nt
atgcctcacattgagagagaagagctcacgcctgaggaaagtgaccaactgcttcttctc
ccgggtggccaccctccattgtggaaccacatggactctattgggtcagtaaggttgcgg
caaagggaaggagctcctggctgttcccaggaggacttgccctgcccctcagacagctct
gagctggtgttggagtgtctacagcaattcaaggtgacggagacacagctgcggcagatc
caagccagcctcctgggctctatggagcaggcactggggggacaggccagccctgcctct
gctgtccagatgctgcccacatatgtggggtccaccccacatggcactgagcaaggggat
tttgtggtgctggagctgggggccacaggggcctcactgcgtgttctgtgggtgaccctg
ttgggtattgagggacataggatggagccccggagccaggagtttgtgatccccccagag
gtgatgctgggtcccggtcagcagctctttgactttgctgcccactgtctgtctgagttc
ctggatgcactccccgtggacaaagagggtctgcagcttgggttcagcttctccttccct
tgtcaccagacgggcctggacagggtgaggcaaagtgggcatggggacagtaggtggagg
agttgcagccccatgaaggctgttggaggaatgacccaacttttctgcccccagagcacc
cttatttcctggaccaaaggttttaggtgcagtggtgtggaaggccacgatgtggtccag
ttgctgcgagatgccatcaagaggcagggggcctacagcatcgatgtggttgccgtggtg
aatgacacagtgggcaccatgatgggctgcgagccaggggttgggccatgtgaggtcggg
cttgttgtagacactggcaccaatgcatgttacatggaggaggcaaggcatgtggcagtg
ctggatgaggaccggggccgcgtctgcatcagcgttgagtggggctccttcagtgatgat
ggggtcctgggaccagtgctgaccacctttgaccatgccttggacagagagtccctgaat
cctggtgcccagaggtttgagaagatgattgggggcttgtacctgggtgagctggtgagg
cttgtgttggctcacctggcccagcgaggggtcctctttggtggctgcacctcccctgcc
ctgctgagccgtggcagcatcctcctggagcatgtggctgagatgaaggacccattggct
ggggcagcccgtgtgcatgctatcctgcgggacatgggcctgagcatgggggcctcggac
gctgagctggtgcagtacgtgtgtgcagccgtgttcactcgggctgcccggctctgtgct
gccgccctggcggctgttcttgcccgcctccagcacagccgggagcagcaggtgcttcag
atcgccgtggccaccggaggccgagtgttcgagcgataccccagtttcctcagcatcctg
caggagaccgtgatgctcctggcccccgaatgtgatgtctccttcattccctctgtggat
gggggtggccggggagtggcaatggtgacggctgtggctgcccgcctggctgctcaccgc
cgcctgctggaagagaccctggcgcctttccggctggaccatgagcagctggcagcggtg
cgggcacagatgcgggaggccatggtcaaggggctccgaggggagtcctcatccctccgc
atgctgcccacttatgtccgggccacacctgatggcactgagcgcggggacttcctggcc
ctggacctggggggcaccaacttccgggtcctcttggtgcgtgtgacagcaggaggtgtg
aagatcaccagccaggtctactccatcccggagtatgtggcccaaggctctgggcagcag
ctcttcgaccacatcgtggactgcattgtggacttccagcagaagcagggcctgagtggg
cagagcctcccgctgggtttcaccttctccttcccatgtaggcagcttggcctcgaccag
ggcatcctcctaaactggacaaagggtttcaatgcatcagactgtgagggccaagacatt
gtgtgtctgttgcgggaagccatcgggcgaagagaggcagtggagctgaatgtggttgcc
attgtcaatgacacggtggggaccatgatgtcctgtggctatgaggatccccgttgcgag
gtcggcctcattgttggaactggcaccaatgcctgctacatggaggagcttcagaatgtg
gcagccgtgcctggggactcaggccacatgtgcatcaatatggagtggggtgcctttggg
gatgatggctctctggacttgcttagaacctgctttgatgcaaatgtggaccaggcatcc
atcaaccctggcaagcagagctttgagaagatgatcagtggcatgtacctgggggagatc
gtccgccacattctcctgcatttgaccagccttggagttctcttccggggccagcagacc
cagggccttcagaccagggacatcttcaagaccaagtttctctctgagattgaaagtgac
agcctggctctgaggcaggtccgaaccatcctggaggatctggggttgtccctgacctca
gatgacgccctgatggtcctggaggtgtgccaggctgtgtcccagcgggctgctcagctc
tgcggggcgggtgtggctgctgtggtggagaagatccgtgagaaccggggcctagaagag
ttgactgtgtccgtaggggtggatgggaccctctacaagctgcatccccacttctctggc
ctggtggcagccacagtgagggagctggcccctcgctgtgtggtcaccttcctgcagtcg
gaagatgggtccggcaaaggtgcagccctggtcactgcggttgcctgccgccttgcccag
atggcccatgtttga
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