Mirounga leonina (Southern elephant seal): 118018488
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Entry
118018488 CDS
T07472
Symbol
PTPN11
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 11 isoform X1
KO
K07293
tyrosine-protein phosphatase non-receptor type 11 [EC:
3.1.3.48
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx04014
Ras signaling pathway
mlx04072
Phospholipase D signaling pathway
mlx04148
Efferocytosis
mlx04360
Axon guidance
mlx04517
IgSF CAM signaling
mlx04625
C-type lectin receptor signaling pathway
mlx04630
JAK-STAT signaling pathway
mlx04650
Natural killer cell mediated cytotoxicity
mlx04660
T cell receptor signaling pathway
mlx04670
Leukocyte transendothelial migration
mlx04722
Neurotrophin signaling pathway
mlx04920
Adipocytokine signaling pathway
mlx04931
Insulin resistance
mlx05168
Herpes simplex virus 1 infection
mlx05205
Proteoglycans in cancer
mlx05208
Chemical carcinogenesis - reactive oxygen species
mlx05211
Renal cell carcinoma
mlx05220
Chronic myeloid leukemia
mlx05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
118018488 (PTPN11)
04630 JAK-STAT signaling pathway
118018488 (PTPN11)
04072 Phospholipase D signaling pathway
118018488 (PTPN11)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
118018488 (PTPN11)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
118018488 (PTPN11)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
118018488 (PTPN11)
04650 Natural killer cell mediated cytotoxicity
118018488 (PTPN11)
04660 T cell receptor signaling pathway
118018488 (PTPN11)
04670 Leukocyte transendothelial migration
118018488 (PTPN11)
09152 Endocrine system
04920 Adipocytokine signaling pathway
118018488 (PTPN11)
09156 Nervous system
04722 Neurotrophin signaling pathway
118018488 (PTPN11)
09158 Development and regeneration
04360 Axon guidance
118018488 (PTPN11)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
118018488 (PTPN11)
05208 Chemical carcinogenesis - reactive oxygen species
118018488 (PTPN11)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
118018488 (PTPN11)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
118018488 (PTPN11)
05211 Renal cell carcinoma
118018488 (PTPN11)
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
118018488 (PTPN11)
09167 Endocrine and metabolic disease
04931 Insulin resistance
118018488 (PTPN11)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
mlx01009
]
118018488 (PTPN11)
Enzymes [BR:
mlx01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
118018488 (PTPN11)
Protein phosphatases and associated proteins [BR:
mlx01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
118018488 (PTPN11)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Y_phosphatase
SH2
SH2_1
PTP-SAK
Tc-R-P
DSPc
Y_phosphatase3
PTPlike_phytase
PTP-NADK
Motif
Other DBs
NCBI-GeneID:
118018488
NCBI-ProteinID:
XP_034872932
LinkDB
All DBs
Position
Unknown
AA seq
617 aa
AA seq
DB search
MKEILLGAREESSEVDGIHGGLRYLWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGD
FTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKY
PLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGES
NDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTR
INAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYK
NILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVND
FWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRE
LKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVV
VHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYM
AVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLTDQTSGDQSPLPPCTPTPSCAEMREDN
ARVYENVGLMQPQKSFR
NT seq
1854 nt
NT seq
+upstream
nt +downstream
nt
atgaaggaaatcttgttgggagctagagaggaatcctctgaagtggatggcattcatggt
ggacttcgttatttatggtttcacccaaacatcactggcgtggaggcagaaaacctgctg
ttgacaagaggagttgatggcagttttttggcgaggcccagtaaaagcaaccctggagac
ttcaccctttccgtcagaagaaatggcgctgtcacccacatcaagattcagaacactggt
gattactatgacttgtacggaggggagaagtttgccactttggctgagttggtccagtat
tacatggaacatcatgggcaattaaaagagaagaatggagatgttattgagcttaaatat
cctctgaactgtgcagatcctacctctgaaaggtggtttcatggacacctctctgggaaa
gaagcagagaaattactaactgagaaaggaaaacacggtagctttctggtacgagagagc
cagagccaccccggagattttgttctgtctgtccgaactggtgacgacaaaggggagagc
aatgatggcaagtctaaagtgacccacgtcatgatccgctgtcaggaactgaaatatgat
gttggtggaggagaacggtttgactctttgacagatcttgtggagcattacaagaagaat
cccatggtggaaacattgggcacagtactacaactcaagcagcccctcaacacaacacgt
atcaatgctgctgaaatagaaagccgggttcgagaactaagcaaattagctgagaccaca
gataaagtcaaacaaggcttttgggaagaatttgagacactacaacaacaggagtgcaaa
cttctctacagccgaaaagagggtcagaggcaagaaaataagaacaaaaatagatataaa
aacatcctgccctttgatcataccagggttgtcctacacgatggtgatcccaatgagcct
gtttcagattacatcaatgcaaatattatcatgcccgagtttgaaaccaaatgcaacaat
tcaaagcccaaaaaaagttacatcgccacacaaggctgcctgcagaacacggtgaacgac
ttttggcggatggtatttcaggagaactcccgagtgattgtcatgacaacgaaggaggtg
gagagaggaaagagtaaatgtgtcaaatactggcctgacgagtatgctctaaaagaatat
ggggtcatgcgtgttaggaacgtcaaagaaagtgctgctcatgactatacattaagagaa
cttaaactttcaaaagttggacaagctctactccaggggaatacagagagaaccgtgtgg
caataccactttcggacctggccggaccacggagtgcccagtgaccctgggggcgtgctg
gacttcctggaggaggtccaccataagcaagagagcattatggacgcagggcctgtggta
gttcactgcagtgctggaatcggcaggacagggacgttcattgtgattgatatccttatt
gacatcatcagagagaaaggcgtcgactgtgacatcgatgttcccaaaaccattcagatg
gtgcggtctcagaggtcagggatggtccagacagaagcacagtaccgattcatctatatg
gccgtccagcattacattgaaacactacagcgcaggattgaagaagagcagaaaagcaag
aggaaagggcatgaatacacaaatattaagtattctctaacggaccagacaagtggagat
cagagtcccctcccgccttgtaccccaacaccatcttgtgcagaaatgagagaagataat
gctagagtctatgaaaacgtgggtctgatgcagccgcagaaaagtttcagatga
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