Mirounga leonina (Southern elephant seal): 118018582
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Entry
118018582 CDS
T07472
Symbol
ACACB
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx00061
Fatty acid biosynthesis
mlx00620
Pyruvate metabolism
mlx00640
Propanoate metabolism
mlx01100
Metabolic pathways
mlx04152
AMPK signaling pathway
mlx04910
Insulin signaling pathway
mlx04920
Adipocytokine signaling pathway
mlx04922
Glucagon signaling pathway
mlx04931
Insulin resistance
mlx04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
118018582 (ACACB)
00640 Propanoate metabolism
118018582 (ACACB)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
118018582 (ACACB)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
118018582 (ACACB)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
118018582 (ACACB)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
118018582 (ACACB)
04922 Glucagon signaling pathway
118018582 (ACACB)
04920 Adipocytokine signaling pathway
118018582 (ACACB)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
118018582 (ACACB)
04931 Insulin resistance
118018582 (ACACB)
Enzymes [BR:
mlx01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
118018582 (ACACB)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
118018582 (ACACB)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
118018582 (ACACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
Motif
Other DBs
NCBI-GeneID:
118018582
NCBI-ProteinID:
XP_034873087
LinkDB
All DBs
Position
Unknown
AA seq
2456 aa
AA seq
DB search
MILLLFLSCLIFFRLTFSWLKIWGKMTDSKQVTKSKSEGSCILSQEAFPASDSSGEPPQK
IEDRSPPPETPDQAEPASHKGPKDACRQRTSRPPPHQNPPGNPCSSDSTPAALQANGTGT
KGLKTRDTNGLSSPAKPQGQRARPLSKEDEKQEYIKRQLMTNFILGSFDDNSSDEDPGAG
LFRESSRKDSRASLGTLSLEAAQTVGEFENPVPAMRPSMSGLHLVKRGRELKKLDLHRDF
TVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPE
DLKANAEYIKMADQYVPVPGGPNNNNYANVELVVDIAKRIPVQAVWAGWGHASENPKLPE
LLCKHEIAFLGPPSEAMWALGDKIASTIVAQTLQIPTLPWSGSGLMVEWTEDDLQQGKRI
TVPEDVYNQGCVKDIDEGLEVAEKIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQS
EIPSSPIFLMKLAEHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIAIPA
VFEFMEQCAVHLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPA
AQLQIAMGVPLSRLKDIRLLYGESPWGVTPISFDTPANPPLARGHVIAARITSENPDEGF
KPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALK
ELSIRGDFRTTVEYLINLLETERFQNNDIDTGWLDHLIAEKVQAEKPDIMLGVVCGALNV
ADAMFRTCMTDFLHSLERGQVLPAASLLNIVDVELIYGGVKYILKVARQSLTMFILIMND
CHIEIDAHRLSDGGLLLSYNGNSYTTYMKEEFDSYRITIGNKTCVFEKENDPTVLRAPSA
GKLMQYMVEDGGHVEAGSSYANMEVMKMIMTLNVQESGRVKYIKRPGAMLEAGCVVARLE
LDDPSKVHPAKPFTGALPSQQTLPIMGEKLHQVFHNVLENLTNVMSGYCLPEPIFSTKLK
EWVQKLMTTLRHPSLPLLELQEIMTNVSGRIPAPVEKSVRRVMAQYASNITSVLCQFPSQ
QIATILDCHAATLQRKAEREVFFMNTQSIVQLVQRYRSGTRGYMKAVVLDLLRRYLRVEH
HFQQAHYDKCVINLREQLKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSEEL
TSILNELTQLSKSEHCKVALRARQVLIASHLPSYELRHNQVETIFLSAIDMYGHQFCPEN
LKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDSTCVVE
FQFMLPSSHPNRMAMPISVTNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFVRNF
DEVISCFANVPREVPLFSKAYTSLYCEEDSKNLREEPIHILNVAIQYADHLEDEELVPIF
RMFVQSKKNILVGCGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLEL
SRMRNFDLTAVPCANHKMHLYLGAAKVKEGAEVTDHRFFIRAIIRHSDLITKEASFEYLQ
NEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRSMVMRYGSRL
WKLRVLQAEVKINIRQTTAGCAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSFGN
KQGPQHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWGTPDKYPKDI
LTYTELVLDPQGQLVEMNRLPGGNEVGMVAFKMRFKTPEYPEGRNVIVIGNDITFRIGSF
GMGEDFLYLRASEMARAEGIPKIYLAANSGACIGLAEEVKHIFQVAWVDPEDPHKGFKYL
YLTPQDYTTISSLNSVHCKHIEEDGESRYVITDIIGKDSGVGVENLRGSGMIAGESSLAY
EEIVTISLVTCRAVGIGAYLVRLGQRVIQVENSHIILTGAGALNKVLGREVYTSNNQLGG
VQIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPLPIITPTDPIDREVGFFPTRAP
YDPRWLLAGRPHPTLKGSWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETR
TVEVVVPADPANLDSEAKIIQQAGQVWLPDSAYKTAQAINDFNREKLPLMIFANWRGFSG
GMKDMYDQMLKFGAYIVDSLRQYKQPILTYIPPYAELRGGSWVVMDSSINPLCIELYADK
ESRANILEPEGTVEIKYRKKDLIKTMRRIDPVYKKLVEQLGMSELSDMDRKDLEGQLKAR
EDLLLPIYHQVAVQFADLHDRPICMLEKGAIADILEWRTSRTFLYWRLRRLLLEDQVKQE
ILQASSELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEEHWQAGDGLRSTICEN
IKCLKRDSVLKAIRGLVQDNPEVARDCIVYMSQHVSPAERAQVLHLLSTVDSPAST
NT seq
7371 nt
NT seq
+upstream
nt +downstream
nt
atgatactgcttctttttctatcttgtttgattttcttccgcttgaccttttcctggtta
aaaatctgggggaaaatgacggactctaagcaagtcaccaagagtaaatcagaagggagc
tgtatcctaagccaggaggccttcccagcctcagacagctcaggggagccaccccagaaa
atcgaggaccgcagccctccaccagagactcctgaccaggctgagccagcctcccacaaa
ggtcccaaagatgcctgtcggcaaagaacttccaggccacccccacaccagaacccccca
ggaaacccctgttcctcggatagcacccccgcagctctccaagccaatgggacagggacc
aaaggcctgaagacccgggataccaatggcctgtcatctccagccaagccccagggccag
cgagccagacccctctccaaagaagacgaaaagcaggagtacatcaagaggcagctgatg
accaacttcatcctgggctcctttgatgacaactcctcagatgaggaccctggcgctggc
ttgttccgagagtcttcccggaaggacagccgggccagcctggggaccctgtccctggag
gctgctcagactgtaggcgagttcgagaacccagtccctgctatgagacccagcatgtcg
ggactccacctggtaaagagaggccgagaactgaagaagctggacctgcacagagacttt
accgtggcctccccggctgagtttgtcacgcgctttgggggggatcgggtcatcgagaag
gtgctcatcgccaacaatggcatcgctgccgtgaagtgcatgcgctccatccgcaggtgg
gcctacgagatgttccgcaacgagcgggccatccggtttgtagtcatggtgaccccagag
gacctgaaggccaatgcagagtatatcaagatggcagatcagtatgtccctgtcccggga
gggcccaacaacaacaattatgccaacgtggagctggttgtggacattgccaagagaatc
cccgtgcaggcggtgtgggctggctggggccatgcttccgaaaaccccaaactgccggag
ctcctgtgcaagcacgagattgctttcttaggccctcccagtgaggccatgtgggccttg
ggagataagatcgcctccaccattgtggcccagacgctgcagatcccaacactgccctgg
agtggaagtggtctgatggtggaatggacagaagatgatctgcagcaggggaaaagaatc
actgtcccagaagatgtttacaaccagggttgtgtgaaagatatagatgagggcttagag
gtggcagaaaaaattggttttcccttgatgatcaaagcatcggaaggcggtggagggaaa
ggaatccggaaggcagagagtgccgaggacttcccaatccttttcagacaagtgcagagt
gagatccctagctcccccatcttcctcatgaagctggccgagcatgcccgacacctggag
gtgcagatcctcgctgaccagtatgggaacgccgtgtccctgttcgggcgtgactgctcc
atccagcggcggcatcagaagatcatcgaggaggcgccggccaccatcgccataccggct
gtgtttgagttcatggagcagtgtgccgtccacctggccaagactgtgggctacgtgagc
gcggggacggtggaatatctctacagccaggatggcagcttccacttcttggagctgaat
ccccgcctgcaggtggagcacccctgcacagagatgatcgccgatgtcaacctgccggcc
gcccagctacagattgccatgggggtgccgctgtcccggctcaaggatatccggcttctc
tacggggagtcgccatggggggtgacgcccatttcgtttgatactcctgccaaccctccg
ctcgcccgaggccatgtcatcgcggccagaatcaccagtgagaaccccgatgaggggttt
aagccaagctctggaacggttcaggaactgaatttccggagcaacaagaacgtgtggggt
tatttcagcgtggcggctgctggtggcttacacgaatttgctgattcccagttcgggcac
tgcttctcctggggagagaaccgggaagaggccatttcgaacatggtggtggctttgaag
gaactgtccatccggggcgacttcaggaccaccgtggagtatctcatcaacctgctggag
accgagcgcttccagaacaacgacatcgacacaggctggttggatcacctcatcgccgag
aaagtgcaggccgagaagccggatatcatgcttggggtggtgtgcggagccttgaacgtg
gccgacgcgatgttcagaacatgcatgacggatttcttacactcgctggaaaggggccag
gtccttcctgcagcttctctgctgaacatcgtggatgtggaattaatttatggaggtgtt
aagtacatcctcaaggtggcccggcaatctctgaccatgttcatcctcatcatgaacgac
tgtcacatcgagatcgacgcccaccggctaagcgacggggggttgctactgtcctataat
ggtaacagctataccacctacatgaaagaagagtttgacagctaccgtattaccatcggc
aacaagacgtgtgtttttgagaaggagaatgatcccacagtcctgagagccccttcggct
gggaagctaatgcagtacatggtggaggacgggggccacgttgaggctgggagcagctac
gccaacatggaggtaatgaagatgatcatgaccctgaacgtgcaggaaagcggccgggtg
aagtacatcaagcgcccgggggccatgctcgaagcaggctgtgtggtggccaggctggag
ctcgatgacccttccaaagtgcacccggccaagccattcacaggagcgctcccttcccag
caaactctgcccatcatgggagagaaactgcaccaggttttccacaatgtcctggaaaac
ctgaccaacgtcatgagtggctactgtctgccggagcctatttttagcacaaagctgaag
gagtgggtgcagaagctcatgacgaccctccggcatccatcactgccactgctggagctg
caagaaatcatgaccaatgtgtccggtcgcatccccgcccccgtggagaagtcggtccgc
agggtgatggcccagtacgccagcaacatcacctcggtgctgtgccagttccccagccag
cagatagccaccatcctggactgccacgcggccaccctgcagcggaaggctgaacgggag
gtcttcttcatgaacacccagagcatcgtgcaactggtccagaggtaccgcagcgggacc
cgcggctacatgaaagcggtggtgttggacctcctgcggagatatttacgggtggagcac
catttccaacaagctcactacgacaagtgtgtgatcaacctcagggagcagctgaagcca
gacatgtcccaggtgctggactgcatcttttcccacgcgcaggtggccaagaagaaccag
ctggtgatcatgttgattgatgagctctgtggcccagacccttccctgtcggaagagctg
acctccatcctcaacgagctcactcagctgagcaaaagcgagcattgcaaagtggccctc
agagccagacaggtgctgattgcctcccacctcccgtcctatgagctgaggcacaaccag
gtggagaccattttcctgtctgccatcgacatgtacggccaccagttctgcccagaaaac
ctcaagaaattaatactctctgaaacgaccatatttgatgtcctgcccactttcttctac
cacgctaacaaagtcgtctgcatggcatccttggaggtttatgtgcggaggggctacatc
gcctatgagttaaacagcttgcagcaccgacagctcccggacagcacctgcgtggtggaa
ttccagttcatgctgccctcctcccacccaaataggatggccatgcccatcagcgtcacc
aaccccgacctgctgaggcacagcaccgagctcttcatggacagtggcttctccccactg
tgtcagcggatgggggccatggtcgccttcaggagatttgaggacttcgtaaggaacttc
gacgaagtcatctcctgctttgccaacgtgccccgggaagtcccgctcttcagcaaggcc
tatacttccctgtactgtgaggaagacagcaagaacctcagagaagagccaatccacatc
ctgaatgtggccatccagtacgcggaccacctggaagatgaggagctggtgccgattttc
cggatgttcgtacagtccaagaaaaacatccttgtgggttgcggactccgaagaatcaca
ttcctgattgcccaagagaaagaatttcccaagtttttcacattcagagcaagagacgag
tttgcagaagatcgcatttaccgtcacctggagcccgccctggcctttcagctggagctc
agccggatgcgcaacttcgatctgaccgctgtgccctgtgccaaccacaagatgcacctt
tacctgggtgcggccaaagtgaaagaaggggcagaagtgacggaccacaggttcttcatc
cgcgccatcatcaggcactcagacctcattacaaaggaagcctcttttgagtacctgcag
aacgagggtgaacgtctgctcctggaggccatggatgagctggaggtggcgttcaacaac
acaagcgtgcgcactgactgcaaccacatcttcctgaacttcgtgcccaccgtcatcatg
gaccccttcaagattgaggagtccgtgcgttccatggttatgcgctatggcagcaggctg
tggaaactccgcgtgctgcaggctgaggtcaagatcaacatccgccagaccactgccggc
tgtgctgttcccatccgcctgttcatcaccaatgagtcgggctactacttggacatcagc
ctctacaaagaagtcactgactccagatctggaaatatcatgtttcactcctttggcaac
aagcagggaccccagcacgggatgctgatcaacactccctatgtcaccaaggatctgctt
caggccaagcgattccaggcccagtccctaggcaccacctacgtctacgacttcccggag
atgttcaggcaggctctctttaaactgtggggcaccccggacaagtaccccaaagacatc
ctgacatacactgaactcgtgctggaccctcagggccagctagtagagatgaaccgcctt
cctggaggaaatgaggtgggcatggtggcattcaaaatgaggttcaagacccccgagtat
ccagaagggcggaacgtgatcgtcatcggcaatgacatcacgttccgcattggatccttt
ggcatgggagaagacttcctgtacctgcgggcgtcggagatggcccgggcagagggtatc
cccaaaatctatctcgcagccaacagtggggcctgtattggccttgcagaggaggtcaag
cacatcttccaggtggcttgggtggacccagaagacccccacaaaggatttaaatacttg
tacctaacgccccaagactacaccacaatcagctccctgaactctgtccattgtaaacac
atcgaggaagacggagaatccaggtatgtcatcacggatatcatcgggaaggacagtggt
gtgggcgtagagaatctcaggggctccggcatgattgcgggggagtcctccctggcttac
gaagagattgtcaccatcagcttggtgacctgccgagccgtggggatcggggcctacttg
gtgaggctgggccagcgagtgatccaggtggaaaactctcacatcatcctgacgggagct
ggtgctctcaacaaggtcctaggcagagaggtttacacctccaacaaccagctgggcggc
gtgcagatcatgcattacaacggcgtgtcccacatcaccgtgccagatgacttcgagggc
gtttacaccatcctggagtggctgtcctacatgccaaaggataatcacagcccactcccc
atcatcacacccacggaccccattgacagagaagttggattcttcccgaccagggctccc
tatgacccccggtggctgcttgcaggaaggcctcaccccactctgaagggatcctggcag
agtggcttctttgaccatggcagtttcaaagaaatcatggcaccttgggcccagaccgtg
gtgacaggacgggcaaggctaggggggatccctgttggagtgattgccgtggagacgcgg
accgtggaggtggtggtgcctgcggaccctgccaacctggattcagaggccaagataatc
cagcaggcgggccaggtgtggctcccagactcggcctacaagacggcccaggccatcaac
gatttcaaccgagagaagttgccgctgatgatctttgccaactggagggggttctccggt
ggcatgaaagacatgtacgaccagatgctaaagtttggagcctacatcgtggacagcctc
aggcagtacaaacagcccatcctgacctacatcccaccctacgcggagctccgggggggc
tcctgggtggtcatggactcctccatcaaccccctgtgcatagaactgtacgcagacaag
gagagcagggcaaatattctggagccggagggaacagtggagattaagtaccgaaagaaa
gatctgataaagaccatgagaaggattgacccagtttacaagaagctcgtggaacagctt
ggaatgtcggagctgtccgacatggaccgcaaggacctggagggccagctgaaggcccgg
gaggatctgctgctgcccatctaccaccaggtggcagtgcagttcgccgacctacacgac
aggcccatctgcatgctggagaagggtgccatcgctgacatcctggagtggaggacctca
cggaccttcttgtactggcgcctgcgccgtctcctgctggaggaccaggtcaagcaggag
atcctgcaggccagcagcgagctgagccacgtgcacatccagtccatgctgcgccggtgg
ttcgtggagaccgagggggccgtcaaggcctacctgtgggacaacaaccaggtggtggta
cagtggctggaagagcattggcaggcgggggacggcctgcgctccaccatctgcgagaac
atcaagtgcttgaagcgagactccgtcctcaaggccatcagaggcctggtgcaggacaac
cctgaagtggccagggactgcattgtgtacatgagccagcacgtcagcccagccgagcgg
gcccaagtccttcacctcctgtccactgtggacagcccagcctccacctga
DBGET
integrated database retrieval system
