KEGG   Mirounga leonina (Southern elephant seal): 118022632
Entry
118022632         CDS       T07472                                 
Symbol
TGFB1
Name
(RefSeq) transforming growth factor beta-1 proprotein isoform X1
  KO
K13375  transforming growth factor beta-1
Organism
mlx  Mirounga leonina (Southern elephant seal)
Pathway
mlx04010  MAPK signaling pathway
mlx04060  Cytokine-cytokine receptor interaction
mlx04068  FoxO signaling pathway
mlx04110  Cell cycle
mlx04148  Efferocytosis
mlx04218  Cellular senescence
mlx04350  TGF-beta signaling pathway
mlx04380  Osteoclast differentiation
mlx04390  Hippo signaling pathway
mlx04659  Th17 cell differentiation
mlx04672  Intestinal immune network for IgA production
mlx04926  Relaxin signaling pathway
mlx04932  Non-alcoholic fatty liver disease
mlx04933  AGE-RAGE signaling pathway in diabetic complications
mlx05140  Leishmaniasis
mlx05142  Chagas disease
mlx05144  Malaria
mlx05145  Toxoplasmosis
mlx05146  Amoebiasis
mlx05152  Tuberculosis
mlx05161  Hepatitis B
mlx05166  Human T-cell leukemia virus 1 infection
mlx05200  Pathways in cancer
mlx05205  Proteoglycans in cancer
mlx05210  Colorectal cancer
mlx05211  Renal cell carcinoma
mlx05212  Pancreatic cancer
mlx05220  Chronic myeloid leukemia
mlx05225  Hepatocellular carcinoma
mlx05226  Gastric cancer
mlx05321  Inflammatory bowel disease
mlx05323  Rheumatoid arthritis
mlx05410  Hypertrophic cardiomyopathy
mlx05414  Dilated cardiomyopathy
mlx05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mlx00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118022632 (TGFB1)
   04350 TGF-beta signaling pathway
    118022632 (TGFB1)
   04390 Hippo signaling pathway
    118022632 (TGFB1)
   04068 FoxO signaling pathway
    118022632 (TGFB1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    118022632 (TGFB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    118022632 (TGFB1)
  09143 Cell growth and death
   04110 Cell cycle
    118022632 (TGFB1)
   04218 Cellular senescence
    118022632 (TGFB1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    118022632 (TGFB1)
   04672 Intestinal immune network for IgA production
    118022632 (TGFB1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    118022632 (TGFB1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    118022632 (TGFB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118022632 (TGFB1)
   05205 Proteoglycans in cancer
    118022632 (TGFB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    118022632 (TGFB1)
   05212 Pancreatic cancer
    118022632 (TGFB1)
   05225 Hepatocellular carcinoma
    118022632 (TGFB1)
   05226 Gastric cancer
    118022632 (TGFB1)
   05220 Chronic myeloid leukemia
    118022632 (TGFB1)
   05211 Renal cell carcinoma
    118022632 (TGFB1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    118022632 (TGFB1)
   05161 Hepatitis B
    118022632 (TGFB1)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    118022632 (TGFB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    118022632 (TGFB1)
   05144 Malaria
    118022632 (TGFB1)
   05145 Toxoplasmosis
    118022632 (TGFB1)
   05140 Leishmaniasis
    118022632 (TGFB1)
   05142 Chagas disease
    118022632 (TGFB1)
  09163 Immune disease
   05323 Rheumatoid arthritis
    118022632 (TGFB1)
   05321 Inflammatory bowel disease
    118022632 (TGFB1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    118022632 (TGFB1)
   05414 Dilated cardiomyopathy
    118022632 (TGFB1)
   05415 Diabetic cardiomyopathy
    118022632 (TGFB1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    118022632 (TGFB1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    118022632 (TGFB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:mlx03110]
    118022632 (TGFB1)
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:mlx04052]
    118022632 (TGFB1)
   00536 Glycosaminoglycan binding proteins [BR:mlx00536]
    118022632 (TGFB1)
Chaperones and folding catalysts [BR:mlx03110]
 Intramolecular chaperones
  Others
   118022632 (TGFB1)
Cytokines and neuropeptides [BR:mlx04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   118022632 (TGFB1)
Glycosaminoglycan binding proteins [BR:mlx00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   118022632 (TGFB1)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta
Other DBs
NCBI-GeneID: 118022632
NCBI-ProteinID: XP_034879179
LinkDB
Position
Unknown
AA seq 391 aa
MPPSGLRLLPLLLPLLWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA
SPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVENSNKI
YEKIKKSPHSIYMLFNTSELREAVPEPVLLSRAELRLLRLKLKVEQHVELYQKYSNDSWR
YLSNRLLAPSDAPEWLSFDVTGVVRQWLSHGGEVEGFRLSAHCSCDSKDNTLQVDINAGL
RSSRRGDLATIHGMNRPFLLLMATPLERAQHLHSSRQRRALDTNYCFSSTEKNCCVRQLY
IDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQ
ALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
NT seq 1176 nt   +upstreamnt  +downstreamnt
atgccgccctccgggctgcggctgctgccgctgctgctgccgctgctgtggctactagtg
ctgacgcctggccggccggccgccggactgtccacctgcaagaccatcgacatggaactg
gtgaagcggaagcgcatcgaggccatccgcggccagatcctgtccaagctgcggctcgcc
agccccccgagccagggggaggtgccgcccggcccgctgcccgaggctgtgctggccctt
tacaacagcacccgcgaccgggtggcgggggagagcgccgagccggagcccgagcctgag
gcggactactacgccaaggaggtcacccgcgtgctaatggtggaaaacagcaacaaaatc
tatgagaaaatcaagaaaagcccgcacagcatatatatgctcttcaacacgtcggagctc
cgagaagcagtgcccgagcccgtcttgctctcccgggcagagttgcgcctgctgaggctc
aagttaaaagtggagcagcacgtggagctgtaccagaaatacagcaacgattcctggcgc
tacctcagcaaccggctgctagcgcccagcgacgcgccagaatggctgtccttcgatgtc
actggagttgtgcggcagtggctgagccacggaggggaagtagagggctttcgcctcagt
gcccactgttcgtgtgacagcaaagataacacactgcaagtggacatcaacgcagggctc
cgttccagccgccgaggtgacctggccaccattcacggcatgaaccggcccttcctgctc
ctcatggccaccccactggagagggcccagcaccttcacagctcccggcagcgccgggcc
ctggacaccaactactgcttcagctccaccgagaagaactgctgcgtgcggcagctctat
atcgacttccggaaggatctgggctggaagtggatccacgagcccaagggctaccacgcc
aacttctgcctggggccctgcccctacatttggagcctggacacgcagtacagcaaggtc
ctggccctgtacaaccagcacaacccgggcgcgtcggcggcgccgtgctgcgtgcctcag
gcgctggagccgctgcccatcgtgtactacgtgggccgcaagcccaaggtggagcagctg
tccaacatgatcgtgcgctcctgcaagtgcagctga

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