KEGG   Mirounga leonina (Southern elephant seal): 118024273
Entry
118024273         CDS       T07472                                 
Symbol
GRB2
Name
(RefSeq) growth factor receptor-bound protein 2
  KO
K04364  growth factor receptor-bound protein 2
Organism
mlx  Mirounga leonina (Southern elephant seal)
Pathway
mlx01521  EGFR tyrosine kinase inhibitor resistance
mlx01522  Endocrine resistance
mlx04010  MAPK signaling pathway
mlx04012  ErbB signaling pathway
mlx04014  Ras signaling pathway
mlx04062  Chemokine signaling pathway
mlx04068  FoxO signaling pathway
mlx04072  Phospholipase D signaling pathway
mlx04150  mTOR signaling pathway
mlx04151  PI3K-Akt signaling pathway
mlx04380  Osteoclast differentiation
mlx04510  Focal adhesion
mlx04517  IgSF CAM signaling
mlx04540  Gap junction
mlx04550  Signaling pathways regulating pluripotency of stem cells
mlx04630  JAK-STAT signaling pathway
mlx04650  Natural killer cell mediated cytotoxicity
mlx04660  T cell receptor signaling pathway
mlx04662  B cell receptor signaling pathway
mlx04664  Fc epsilon RI signaling pathway
mlx04714  Thermogenesis
mlx04722  Neurotrophin signaling pathway
mlx04910  Insulin signaling pathway
mlx04912  GnRH signaling pathway
mlx04915  Estrogen signaling pathway
mlx04917  Prolactin signaling pathway
mlx04926  Relaxin signaling pathway
mlx04935  Growth hormone synthesis, secretion and action
mlx05034  Alcoholism
mlx05160  Hepatitis C
mlx05161  Hepatitis B
mlx05163  Human cytomegalovirus infection
mlx05165  Human papillomavirus infection
mlx05200  Pathways in cancer
mlx05203  Viral carcinogenesis
mlx05205  Proteoglycans in cancer
mlx05206  MicroRNAs in cancer
mlx05207  Chemical carcinogenesis - receptor activation
mlx05208  Chemical carcinogenesis - reactive oxygen species
mlx05210  Colorectal cancer
mlx05211  Renal cell carcinoma
mlx05213  Endometrial cancer
mlx05214  Glioma
mlx05215  Prostate cancer
mlx05220  Chronic myeloid leukemia
mlx05221  Acute myeloid leukemia
mlx05223  Non-small cell lung cancer
mlx05224  Breast cancer
mlx05225  Hepatocellular carcinoma
mlx05226  Gastric cancer
mlx05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:mlx00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118024273 (GRB2)
   04012 ErbB signaling pathway
    118024273 (GRB2)
   04014 Ras signaling pathway
    118024273 (GRB2)
   04630 JAK-STAT signaling pathway
    118024273 (GRB2)
   04068 FoxO signaling pathway
    118024273 (GRB2)
   04072 Phospholipase D signaling pathway
    118024273 (GRB2)
   04151 PI3K-Akt signaling pathway
    118024273 (GRB2)
   04150 mTOR signaling pathway
    118024273 (GRB2)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    118024273 (GRB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    118024273 (GRB2)
   04540 Gap junction
    118024273 (GRB2)
   04550 Signaling pathways regulating pluripotency of stem cells
    118024273 (GRB2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    118024273 (GRB2)
   04660 T cell receptor signaling pathway
    118024273 (GRB2)
   04662 B cell receptor signaling pathway
    118024273 (GRB2)
   04664 Fc epsilon RI signaling pathway
    118024273 (GRB2)
   04062 Chemokine signaling pathway
    118024273 (GRB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    118024273 (GRB2)
   04912 GnRH signaling pathway
    118024273 (GRB2)
   04915 Estrogen signaling pathway
    118024273 (GRB2)
   04917 Prolactin signaling pathway
    118024273 (GRB2)
   04926 Relaxin signaling pathway
    118024273 (GRB2)
   04935 Growth hormone synthesis, secretion and action
    118024273 (GRB2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    118024273 (GRB2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    118024273 (GRB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    118024273 (GRB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118024273 (GRB2)
   05206 MicroRNAs in cancer
    118024273 (GRB2)
   05205 Proteoglycans in cancer
    118024273 (GRB2)
   05207 Chemical carcinogenesis - receptor activation
    118024273 (GRB2)
   05208 Chemical carcinogenesis - reactive oxygen species
    118024273 (GRB2)
   05203 Viral carcinogenesis
    118024273 (GRB2)
   05231 Choline metabolism in cancer
    118024273 (GRB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    118024273 (GRB2)
   05225 Hepatocellular carcinoma
    118024273 (GRB2)
   05226 Gastric cancer
    118024273 (GRB2)
   05214 Glioma
    118024273 (GRB2)
   05221 Acute myeloid leukemia
    118024273 (GRB2)
   05220 Chronic myeloid leukemia
    118024273 (GRB2)
   05211 Renal cell carcinoma
    118024273 (GRB2)
   05215 Prostate cancer
    118024273 (GRB2)
   05213 Endometrial cancer
    118024273 (GRB2)
   05224 Breast cancer
    118024273 (GRB2)
   05223 Non-small cell lung cancer
    118024273 (GRB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    118024273 (GRB2)
   05160 Hepatitis C
    118024273 (GRB2)
   05163 Human cytomegalovirus infection
    118024273 (GRB2)
   05165 Human papillomavirus infection
    118024273 (GRB2)
  09165 Substance dependence
   05034 Alcoholism
    118024273 (GRB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    118024273 (GRB2)
   01522 Endocrine resistance
    118024273 (GRB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mlx04131]
    118024273 (GRB2)
Membrane trafficking [BR:mlx04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    118024273 (GRB2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH3_3 SH2_2 DUF5093 DUF7145 hSH3 SH3_4
Other DBs
NCBI-GeneID: 118024273
NCBI-ProteinID: XP_034881933
LinkDB
Position
Unknown
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagctactgctgacgacgagctgagcttcaaa
aggggggacatcctcaaggttttgaatgaagaatgtgatcagaactggtacaaggcagaa
ctcaatgggaaagatggcttcattcccaagaattacatagaaatgaaaccacatccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgcttagcaaacagcggcatgac
ggggcgtttcttatccgagagagtgagagtgccccgggggacttctccctgtccgtcaag
ttcggaaatgatgtgcagcacttcaaggtgctccgagatggagctggaaagtatttcctc
tgggtggtgaaattcaattctctgaatgagctggtggattatcacagatctacatctgtc
tccagaaaccagcagatattcctccgggacatagaacaggtgccccagcaaccgacgtac
gtccaggccctctttgactttgatccccaggaggatggagagctgggattccgtcgggga
gactttatccacgtcatggataactcagaccccaactggtggaaaggggcctgccacggg
cagaccggcatgtttccccgcaattacgtcacccctgtgaaccggaacgtctaa

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