Mirounga leonina (Southern elephant seal): 118025717
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Entry
118025717 CDS
T07472
Symbol
PTPN6
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 6
KO
K05697
tyrosine-protein phosphatase non-receptor type 6 [EC:
3.1.3.48
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx04148
Efferocytosis
mlx04520
Adherens junction
mlx04630
JAK-STAT signaling pathway
mlx04650
Natural killer cell mediated cytotoxicity
mlx04660
T cell receptor signaling pathway
mlx04662
B cell receptor signaling pathway
mlx05140
Leishmaniasis
mlx05205
Proteoglycans in cancer
mlx05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
118025717 (PTPN6)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
118025717 (PTPN6)
09144 Cellular community - eukaryotes
04520 Adherens junction
118025717 (PTPN6)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
118025717 (PTPN6)
04660 T cell receptor signaling pathway
118025717 (PTPN6)
04662 B cell receptor signaling pathway
118025717 (PTPN6)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
118025717 (PTPN6)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
118025717 (PTPN6)
09174 Infectious disease: parasitic
05140 Leishmaniasis
118025717 (PTPN6)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
mlx01009
]
118025717 (PTPN6)
Enzymes [BR:
mlx01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
118025717 (PTPN6)
Protein phosphatases and associated proteins [BR:
mlx01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
118025717 (PTPN6)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Y_phosphatase
SH2
PTP-SAK
SH2_1
Tc-R-P
DSPc
PTPlike_phytase
Y_phosphatase3
PTP-NADK
Motif
Other DBs
NCBI-GeneID:
118025717
NCBI-ProteinID:
XP_034884217
LinkDB
All DBs
Position
Unknown
AA seq
595 aa
AA seq
DB search
MVRWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDF
YDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGGQA
ETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEGGRYTVGG
SETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTA
KAGFWEEFESLQKQEVKNLHQRLEGQRPENKSKNRYKNILPFDHTRVILQGRDSNIPGSD
YINANYVKNQLLGPDENTKTYIASQGCLEATVNDFWQMAWQENTRVIVMTTREVEKGRNK
CVPYWPEVGTQRVYGPYVVTNCREHDTAEYKLRTLQVSPLENGDLVREIWHYQYLSWPDH
GVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMESISTKGLDC
DIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVMQSQKGRESEYGNIT
YPPAMKNAHAKASRTSSKHKEDVYENLHSKNKKEEKMKKQRSADKEKSKGSLKRK
NT seq
1788 nt
NT seq
+upstream
nt +downstream
nt
atggtgaggtggtttcaccgagacctcagcgggctggacgcggagaccctgctcaagggc
cgcggcgtccatgggagcttcttggctcggcccagtcgcaagaaccagggtgacttctcc
ctctccgtcagggtgggggatcaggtgacccatattcggatccagaactcgggcgatttc
tatgacctgtatggaggcgagaagtttgcgacgctgacagagctcgtggagtactacaca
cagcagcagggcgtcctgcaggatcgagatggcaccatcatccacctcaagtacccgctg
aactgttccgaccccaccagtgagaggtggtaccatggtcacatgtctggggggcaggca
gagacactgctgcaggccaagggtgagccctggacatttctggtgcgtgagagtctcagc
cagcctggagattttgtgctgtccgtgctcagcgaccagcccaaggctggcccaggctcc
ccgctcagagtcactcatatcaaggtcatgtgtgagggtggacgctacaccgtgggtggt
tcagagacctttgacagcctcacagacctggtggagcatttcaagaagacagggatcgag
gaggcctcgggtgcattcgtctacctgcggcagccatactatgccactcgggtgaatgca
gctgacattgagaatcgggtcttggaactcaacaagaagcaggagtcggaggacacagcc
aaagccggcttctgggaggagtttgagagtctgcagaagcaggaggtaaagaacttgcac
cagcgtctggaagggcagcggccagagaataagagcaagaaccgttacaagaacattctc
ccgtttgaccatacccgagtgatcctgcagggacgcgacagtaacatccctgggtccgac
tacatcaacgccaactacgtcaagaaccagctgctaggccccgatgagaacactaagacc
tacattgccagccagggctgcctggaggccacagtcaacgacttctggcagatggcatgg
caggagaacacccgcgtcatcgtcatgaccacccgagaggtggagaaaggccggaacaag
tgtgtcccatactggccggaggtgggcacgcagcgcgtctacggaccctacgtggtaacc
aattgcagggagcacgacacagcggagtacaagctccgtaccttacaggtctccccgctg
gagaatggggacctggttcgagagatctggcactaccagtacctgagctggcctgaccat
ggggtccccagtgagcctgggggtgtcctcagcttcctggaccagatcaaccagcggcag
gaaagtctgcctcacgcgggacccatcattgtgcactgcagcgcaggcattggccgcacg
ggcaccatcatcgtcatcgacatgctcatggagagcatctccaccaaggggttggactgt
gacatcgacatccagaagacgatccagatggtgcgggcgcagcgctcgggcatggtgcag
acggaggcgcagtacaagttcatctatgtggccattgcccagttcatcgaaaccaccaag
aagaagctggaggtcatgcagtcccagaagggccgggagtcagagtacgggaacatcacc
taccccccagccatgaagaacgcccatgccaaggcctcccgcacctcttccaaacacaag
gaggatgtatatgagaacttgcacagtaagaacaagaaggaggagaagatgaagaagcag
cggtcggcggacaaggagaagagcaagggttcccttaagaggaagtga
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