Mirounga leonina (Southern elephant seal): 118025809
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Entry
118025809 CDS
T07472
Symbol
CACNA1C
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1C isoform X1
KO
K04850
voltage-dependent calcium channel L type alpha-1C
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx04010
MAPK signaling pathway
mlx04020
Calcium signaling pathway
mlx04022
cGMP-PKG signaling pathway
mlx04024
cAMP signaling pathway
mlx04260
Cardiac muscle contraction
mlx04261
Adrenergic signaling in cardiomyocytes
mlx04270
Vascular smooth muscle contraction
mlx04713
Circadian entrainment
mlx04720
Long-term potentiation
mlx04723
Retrograde endocannabinoid signaling
mlx04724
Glutamatergic synapse
mlx04725
Cholinergic synapse
mlx04726
Serotonergic synapse
mlx04727
GABAergic synapse
mlx04728
Dopaminergic synapse
mlx04742
Taste transduction
mlx04911
Insulin secretion
mlx04912
GnRH signaling pathway
mlx04921
Oxytocin signaling pathway
mlx04924
Renin secretion
mlx04925
Aldosterone synthesis and secretion
mlx04927
Cortisol synthesis and secretion
mlx04929
GnRH secretion
mlx04930
Type II diabetes mellitus
mlx04934
Cushing syndrome
mlx04935
Growth hormone synthesis, secretion and action
mlx05010
Alzheimer disease
mlx05020
Prion disease
mlx05022
Pathways of neurodegeneration - multiple diseases
mlx05031
Amphetamine addiction
mlx05207
Chemical carcinogenesis - receptor activation
mlx05410
Hypertrophic cardiomyopathy
mlx05412
Arrhythmogenic right ventricular cardiomyopathy
mlx05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
118025809 (CACNA1C)
04020 Calcium signaling pathway
118025809 (CACNA1C)
04024 cAMP signaling pathway
118025809 (CACNA1C)
04022 cGMP-PKG signaling pathway
118025809 (CACNA1C)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
118025809 (CACNA1C)
04929 GnRH secretion
118025809 (CACNA1C)
04912 GnRH signaling pathway
118025809 (CACNA1C)
04921 Oxytocin signaling pathway
118025809 (CACNA1C)
04935 Growth hormone synthesis, secretion and action
118025809 (CACNA1C)
04924 Renin secretion
118025809 (CACNA1C)
04925 Aldosterone synthesis and secretion
118025809 (CACNA1C)
04927 Cortisol synthesis and secretion
118025809 (CACNA1C)
09153 Circulatory system
04260 Cardiac muscle contraction
118025809 (CACNA1C)
04261 Adrenergic signaling in cardiomyocytes
118025809 (CACNA1C)
04270 Vascular smooth muscle contraction
118025809 (CACNA1C)
09156 Nervous system
04724 Glutamatergic synapse
118025809 (CACNA1C)
04727 GABAergic synapse
118025809 (CACNA1C)
04725 Cholinergic synapse
118025809 (CACNA1C)
04728 Dopaminergic synapse
118025809 (CACNA1C)
04726 Serotonergic synapse
118025809 (CACNA1C)
04720 Long-term potentiation
118025809 (CACNA1C)
04723 Retrograde endocannabinoid signaling
118025809 (CACNA1C)
09157 Sensory system
04742 Taste transduction
118025809 (CACNA1C)
09159 Environmental adaptation
04713 Circadian entrainment
118025809 (CACNA1C)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
118025809 (CACNA1C)
09164 Neurodegenerative disease
05010 Alzheimer disease
118025809 (CACNA1C)
05020 Prion disease
118025809 (CACNA1C)
05022 Pathways of neurodegeneration - multiple diseases
118025809 (CACNA1C)
09165 Substance dependence
05031 Amphetamine addiction
118025809 (CACNA1C)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
118025809 (CACNA1C)
05412 Arrhythmogenic right ventricular cardiomyopathy
118025809 (CACNA1C)
05414 Dilated cardiomyopathy
118025809 (CACNA1C)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
118025809 (CACNA1C)
04934 Cushing syndrome
118025809 (CACNA1C)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
mlx04040
]
118025809 (CACNA1C)
Ion channels [BR:
mlx04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
118025809 (CACNA1C)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
CAC1F_C
PKD_channel
DUF4834
Motif
Other DBs
NCBI-GeneID:
118025809
NCBI-ProteinID:
XP_034884430
LinkDB
All DBs
Position
Unknown
AA seq
1725 aa
AA seq
DB search
MADCMLSIDVLFLVLDMIILSVKGGTPAGLLDQKKGKFAWFSHSTETHVSMPTSETESVN
TENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVF
LNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFI
VCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLL
LLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDG
IMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKER
KKLARTASPEKKQEVVEKPAVEETKEEKIELKSITADGESPPTTKINMDDLQPNENEDKS
PYANPENTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHR
IVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAY
GAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGL
KHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYIT
YKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPI
YNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALK
ARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILN
MLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPFM
NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYA
VIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPES
EPSNSTEGEMPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLD
EFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGT
VMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTV
GKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTA
EEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSCYQSDGRSAFPQTFTTQRPLHINKAAN
SQGDTGSPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPRPTGYPSAVSTVEGRG
PPLSPAVRVQEAAWKLSSKRCHSRESQIAMVCQEEVSQAEPYDVRMSEDTEYCSEPSLIS
TEMLSYQDDENRQLTPPEEDKRGVQQSPKRGFLRSASLGRRASFHLECLKRQKNQGGDVS
QKTVLPLHLVHHQALAVAGLSPLLQRSHSPSTSPRPCATPPATPGSRGWPPQPIPTLRLE
GAESSEKLNSSFPSIHCSSWSGEPTPCAGGSSAIRRARPVSLTVPSQAGARGRQFHGSAS
SLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGTQQSPNGTL
LPFVNCRDPGQDRAGGQEGESCTTARACRRSEEERQDSRAHTGSL
NT seq
5178 nt
NT seq
+upstream
nt +downstream
nt
atggctgactgcatgctttctattgatgtcttgttcctggttcttgacatgatcatcttg
tctgtgaaaggaggcacaccagcgggcttgcttgatcagaagaaagggaagtttgcttgg
tttagtcactccacagaaacccatgtgagcatgcccacaagcgagaccgagtctgtcaac
accgaaaacgtggctggaggtgacatcgagggagagaactgcggggccaggctggcccac
cggatttccaaatcaaagttcagccgctactggcgccggtggaaccggttctgcagaaga
aagtgtcgtgccgcagtcaagtctaatgtcttctactggcttgtgatcttcctggtgttc
ctcaacacgctcaccatcgcctcggaacactacaaccagccccactggctcacggaggtg
caagacacggccaacaaggcactgctggcccttttcactgcagagatgctgctgaagatg
tacagcctaggcctgcaggcctactttgtgtccctcttcaaccgctttgactgcttcatc
gtgtgcgggggcatcctggagaccatcctggtggagaccaagatcatgtctcccttgggc
atctctgtgctgagatgtgtccggctgctgcggatatttaaaatcacaaggtactggaac
tccttaagcaacctggtggcatccttgctgaattctgtgcgctccattgcttccctgctg
ctgctcctcttcctcttcatcatcatcttctctctcctggggatgcagctctttggggga
aagttcaactttgatgaaatgcagacccggaggagcacatttgataactttccccagtcc
ctcctcactgtgtttcagatcctgaccggggaggactggaattcggtgatgtatgatggg
atcatggcttatggcggcccctcttttccagggatgttagtctgtatttacttcatcatc
ctcttcatctgtggaaactatatcctactgaatgtgttcttggccattgctgtggacaac
ctggctgatgctgagagcctcacatctgcccaaaaggaggaggaagaagagaaggagaga
aagaagctggccaggactgccagcccagagaagaaacaagaggtggtagagaagccagca
gtggaggagaccaaggaggagaaaattgaactgaaatccattacagctgatggagagtcc
ccacccaccaccaagatcaacatggatgacctccagcccaatgaaaatgaggataagagt
ccctacgcaaacccagaaaatacaggagaagaggatgaggaggagcctgagatgcctgtg
ggcccccgcccacgaccactctctgagctgcaccttaaggaaaaggcagtgcccatgcca
gaagccagtgcgtttttcatcttcagccccaacaacagatttcgcctccagtgtcaccgc
atcgtcaatgacacgatcttcaccaacctgatcctcttcttcattctgctcagcagcatt
tccctggcagctgaggaccccgtccagcacacctccttcaggaaccatattctgttttat
tttgacattgttttcactaccattttcaccattgaaattgctctgaagatgactgcttat
ggggctttcctacacaagggctctttttgccgaaactacttcaacatcttggacctgctg
gtggtcagcgtgtccctcatttcctttggcatccagtccagcgcaatcaacgtggtgaag
atcttacgagtcctgcgcgtcctcaggcccctgagggccatcaacagggccaaggggcta
aagcacgtggttcagtgcgtgtttgttgccatccggaccatcgggaacatcgtgattgtc
accacactgcttcagttcatgttcgcctgcatcggggtccagcttttcaagggaaagctc
tacacctgctcagatagttccaaacagactgaggcggaatgcaagggtaactacatcaca
tacaaggacggggaggtcgaccaccccatcatccaaccccgcagctgggagaacagcaag
tttgactttgacaatgttctggcggccatgatggccctctttaccgtctctacctttgag
gggtggccagagctgctgtaccgctccatcgactcccacacagaagacaagggccccatc
tacaactaccgtgtggagatctccatctttttcatcatctatatcatcatcattgccttc
ttcatgatgaatatcttcgtgggtttcgtcattgtcaccttccaggagcagggggagcag
gaatacaagaactgtgagctggacaagaaccagcgacagtgcgtggaatatgccctcaag
gcccggcccctgcggaggtacattcccaagaaccagcaccagtacaaagtgtggtacgtg
gtcaactccacctactttgaatacctgatgttcgtcctcatcctgctcaacaccatctgc
ttggccatgcagcactacggccagagctgcctcttcaaaattgccatgaacatcctcaac
atgctcttcactggcctcttcaccgtggagatgattctgaagctcattgccttcaaaccc
aagcactatttctgtgatgcatggaatacatttgacgccttgattgttgtgggtagcatt
gttgatatagcaatcaccgaggtaaacccagctgaacatacccaatgctctccctttatg
aacgcagaggagaactcccgcatctccatcaccttcttccgcctcttccgggtcatgcgc
ctggtcaagctgctgagccgcggggagggcattcggaccctgctgtggaccttcatcaag
tccttccaggccctgccttatgtggctcttctgatagtgatgctgttcttcatctacgca
gtgatcgggatgcaggtgtttgggaaaattgccctgaatgacaccacagagatcaaccgg
aacaacaacttccagaccttcccccaagctgtgctgcttctcttcaggtgtgccacaggg
gaggcatggcaggacatcatgctggcctgcatgccagggaagaagtgtgcccccgagtcg
gagcccagcaacagcacagaaggcgaaatgccctgtggcagcagcttcgcggtcttctac
ttcatcagcttctacatgctctgtgccttcctgatcatcaacctctttgtagccgtcatc
atggacaactttgactacctgacaagggactggtcaattcttggtccccatcatctggat
gaatttaaaagaatctgggcagagtatgatcctgaagccaagggtcgtatcaaacaccta
gatgtggtgaccctactccggcggattcagcccccactgggttttgggaagttgtgccct
caccgcgtggcttgcaaacgcctggtctccatgaacatgcctctgaacagtgatgggaca
gtcatgttcaatgccaccctgtttgccctggtccggacagccctgcgaattaaaacagaa
ggaaacctagaacaagccaacgaggagctgcgggccataatcaagaagatctggaagcgg
accagtatgaagctgctggaccaagtagtgcccccagcaggtgatgatgaggtcacggtt
ggcaagttttatgctactttcctgatccaggagtacttccggaaattcaagaagcgcaaa
gagcagggtctggtgggcaaaccctcccagaggaacgccctatccctgcaggctggcttg
cgcacgctgcatgacatcgggcctgagatccgacgggccatctctggagatctgacggcc
gaggaggagctggacaaggccatgaaggaggctgtgtctgctgcctccgaagacgacatc
ttcaggagggccggcggcctattcggcaaccacgtcagctgctaccaaagcgacggccgg
agcgccttcccccagaccttcactacccagcgcccactgcacatcaacaaggcagctaac
agccaaggcgacaccgggtcgccgtcccacgagaaactggtggactccactttcaccccc
agcagctactcgtccactggctccaacgccaacatcaacaatgccaacaacactgccctg
ggccgcttcccccgccccactggctaccccagcgcggtcagcaccgtagagggccgtggg
ccccccttgtctcctgccgtccgggtacaggaggcagcctggaagctcagctccaagagg
tgccactcccgggagagccagatagccatggtgtgtcaggaggaggtctctcaggctgag
ccctatgacgtgcggatgagcgaagacaccgagtactgcagcgagcccagcctgatctcc
acagagatgctctcctatcaggacgatgaaaatcggcaattaacaccacctgaggaggac
aagagaggtgtccagcaatctccaaagaggggtttcctccgctctgcctcactaggtcga
agggcctccttccacctggaatgtctgaagcgacagaagaatcaagggggagacgtctct
cagaagacagttctgcccttgcatctggttcatcatcaggcattggcagtggctggcctg
agccccctcctgcagagaagccattcccccagcacgtcccccaggccgtgcgccaccccc
ccagccacaccgggcagccgaggctggcccccacagccgatccccaccctgaggctggag
ggcgccgagtccagtgagaaactcaacagcagcttcccgtccatccactgcagctcctgg
tcaggggagcccacgccctgcgctgggggcagcagcgccatccggagagcccggccggtg
tccctcactgtgcccagccaggctggggcccggggcaggcagttccacggcagtgccagc
agtctggtggaagcggtcttgatttcagaaggactggggcagtttgctcaagatcccaag
tttatcgaggtcacaacccaggagctggctgatgcctgtgacatgaccatagaggagatg
gagaacgccgccgacaacatcctcagtgggggcacccagcagagccccaacggcacccta
ctaccttttgttaactgcagggacccggggcaggacagagcggggggccaagagggcgag
agctgcaccacggctcgggcgtgtcggaggagcgaggaggagcgccaggacagcagagcc
cacaccggcagcctgtag
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integrated database retrieval system
