KEGG   Mirounga leonina (Southern elephant seal): 118027255
Entry
118027255         CDS       T07472                                 
Symbol
TNF
Name
(RefSeq) tumor necrosis factor
  KO
K03156  tumor necrosis factor superfamily, member 2
Organism
mlx  Mirounga leonina (Southern elephant seal)
Pathway
mlx01523  Antifolate resistance
mlx04010  MAPK signaling pathway
mlx04060  Cytokine-cytokine receptor interaction
mlx04061  Viral protein interaction with cytokine and cytokine receptor
mlx04064  NF-kappa B signaling pathway
mlx04071  Sphingolipid signaling pathway
mlx04150  mTOR signaling pathway
mlx04210  Apoptosis
mlx04217  Necroptosis
mlx04350  TGF-beta signaling pathway
mlx04380  Osteoclast differentiation
mlx04612  Antigen processing and presentation
mlx04620  Toll-like receptor signaling pathway
mlx04621  NOD-like receptor signaling pathway
mlx04622  RIG-I-like receptor signaling pathway
mlx04625  C-type lectin receptor signaling pathway
mlx04640  Hematopoietic cell lineage
mlx04650  Natural killer cell mediated cytotoxicity
mlx04657  IL-17 signaling pathway
mlx04660  T cell receptor signaling pathway
mlx04664  Fc epsilon RI signaling pathway
mlx04668  TNF signaling pathway
mlx04920  Adipocytokine signaling pathway
mlx04930  Type II diabetes mellitus
mlx04931  Insulin resistance
mlx04932  Non-alcoholic fatty liver disease
mlx04933  AGE-RAGE signaling pathway in diabetic complications
mlx04936  Alcoholic liver disease
mlx04940  Type I diabetes mellitus
mlx05010  Alzheimer disease
mlx05014  Amyotrophic lateral sclerosis
mlx05020  Prion disease
mlx05022  Pathways of neurodegeneration - multiple diseases
mlx05132  Salmonella infection
mlx05133  Pertussis
mlx05134  Legionellosis
mlx05135  Yersinia infection
mlx05140  Leishmaniasis
mlx05142  Chagas disease
mlx05143  African trypanosomiasis
mlx05144  Malaria
mlx05145  Toxoplasmosis
mlx05146  Amoebiasis
mlx05152  Tuberculosis
mlx05160  Hepatitis C
mlx05161  Hepatitis B
mlx05163  Human cytomegalovirus infection
mlx05164  Influenza A
mlx05165  Human papillomavirus infection
mlx05166  Human T-cell leukemia virus 1 infection
mlx05168  Herpes simplex virus 1 infection
mlx05169  Epstein-Barr virus infection
mlx05170  Human immunodeficiency virus 1 infection
mlx05171  Coronavirus disease - COVID-19
mlx05205  Proteoglycans in cancer
mlx05310  Asthma
mlx05321  Inflammatory bowel disease
mlx05322  Systemic lupus erythematosus
mlx05323  Rheumatoid arthritis
mlx05330  Allograft rejection
mlx05332  Graft-versus-host disease
mlx05410  Hypertrophic cardiomyopathy
mlx05414  Dilated cardiomyopathy
mlx05417  Lipid and atherosclerosis
mlx05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mlx00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118027255 (TNF)
   04350 TGF-beta signaling pathway
    118027255 (TNF)
   04064 NF-kappa B signaling pathway
    118027255 (TNF)
   04668 TNF signaling pathway
    118027255 (TNF)
   04071 Sphingolipid signaling pathway
    118027255 (TNF)
   04150 mTOR signaling pathway
    118027255 (TNF)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    118027255 (TNF)
   04061 Viral protein interaction with cytokine and cytokine receptor
    118027255 (TNF)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    118027255 (TNF)
   04217 Necroptosis
    118027255 (TNF)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    118027255 (TNF)
   04620 Toll-like receptor signaling pathway
    118027255 (TNF)
   04621 NOD-like receptor signaling pathway
    118027255 (TNF)
   04622 RIG-I-like receptor signaling pathway
    118027255 (TNF)
   04625 C-type lectin receptor signaling pathway
    118027255 (TNF)
   04650 Natural killer cell mediated cytotoxicity
    118027255 (TNF)
   04612 Antigen processing and presentation
    118027255 (TNF)
   04660 T cell receptor signaling pathway
    118027255 (TNF)
   04657 IL-17 signaling pathway
    118027255 (TNF)
   04664 Fc epsilon RI signaling pathway
    118027255 (TNF)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    118027255 (TNF)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    118027255 (TNF)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    118027255 (TNF)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    118027255 (TNF)
   05170 Human immunodeficiency virus 1 infection
    118027255 (TNF)
   05161 Hepatitis B
    118027255 (TNF)
   05160 Hepatitis C
    118027255 (TNF)
   05171 Coronavirus disease - COVID-19
    118027255 (TNF)
   05164 Influenza A
    118027255 (TNF)
   05168 Herpes simplex virus 1 infection
    118027255 (TNF)
   05163 Human cytomegalovirus infection
    118027255 (TNF)
   05169 Epstein-Barr virus infection
    118027255 (TNF)
   05165 Human papillomavirus infection
    118027255 (TNF)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    118027255 (TNF)
   05135 Yersinia infection
    118027255 (TNF)
   05133 Pertussis
    118027255 (TNF)
   05134 Legionellosis
    118027255 (TNF)
   05152 Tuberculosis
    118027255 (TNF)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    118027255 (TNF)
   05144 Malaria
    118027255 (TNF)
   05145 Toxoplasmosis
    118027255 (TNF)
   05140 Leishmaniasis
    118027255 (TNF)
   05142 Chagas disease
    118027255 (TNF)
   05143 African trypanosomiasis
    118027255 (TNF)
  09163 Immune disease
   05310 Asthma
    118027255 (TNF)
   05322 Systemic lupus erythematosus
    118027255 (TNF)
   05323 Rheumatoid arthritis
    118027255 (TNF)
   05321 Inflammatory bowel disease
    118027255 (TNF)
   05330 Allograft rejection
    118027255 (TNF)
   05332 Graft-versus-host disease
    118027255 (TNF)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    118027255 (TNF)
   05014 Amyotrophic lateral sclerosis
    118027255 (TNF)
   05020 Prion disease
    118027255 (TNF)
   05022 Pathways of neurodegeneration - multiple diseases
    118027255 (TNF)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    118027255 (TNF)
   05418 Fluid shear stress and atherosclerosis
    118027255 (TNF)
   05410 Hypertrophic cardiomyopathy
    118027255 (TNF)
   05414 Dilated cardiomyopathy
    118027255 (TNF)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    118027255 (TNF)
   04940 Type I diabetes mellitus
    118027255 (TNF)
   04936 Alcoholic liver disease
    118027255 (TNF)
   04932 Non-alcoholic fatty liver disease
    118027255 (TNF)
   04931 Insulin resistance
    118027255 (TNF)
   04933 AGE-RAGE signaling pathway in diabetic complications
    118027255 (TNF)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    118027255 (TNF)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:mlx04052]
    118027255 (TNF)
   00536 Glycosaminoglycan binding proteins [BR:mlx00536]
    118027255 (TNF)
Cytokines and neuropeptides [BR:mlx04052]
 Cytokines
  Tumor necrosis fators
   118027255 (TNF)
Glycosaminoglycan binding proteins [BR:mlx00536]
 Heparan sulfate / Heparin
  Cytokines
   118027255 (TNF)
SSDB
Motif
Pfam: TNF ANAPC16
Other DBs
NCBI-GeneID: 118027255
NCBI-ProteinID: XP_034886361
LinkDB
Position
Unknown
AA seq 233 aa
MSTESMIRDVELAEEALPKKAGGPQGSRRFLCLSLFSFLLVAGATTLFCLLHFGVIGPQR
EELPDGLQLINPLAQTVKSSSRTPSDKPVAHVVANPEAEGQLQWLSRRANALLANGVELT
DNQLIVPSDGLYLIYSQVLFKGQGCRSTHVLLTHTISRFAVSYQTKVNLLSAIKSPCQRE
TPEGTEAKPWYEPIYLGGVFQLEKGDRLSAEINLPDYLDFAESGQVYFGIIAL
NT seq 702 nt   +upstreamnt  +downstreamnt
atgagcactgaaagcatgatccgggacgtggagctggccgaggaggcactccctaagaag
gcagggggcccccagggctccagaaggttcttgtgcctcagcctcttctccttcctcctc
gttgcaggagccaccacgctcttctgcctgttgcacttcggagtgatcggcccccagagg
gaagagctcccagatggcctccaactaatcaaccctctggcccagacagtcaaatcatct
tctcgaactccaagtgacaagcctgtagctcatgttgtagcaaaccccgaagctgagggg
caactccagtggctgagccggcgtgccaatgccctcctggccaatggtgtggagctgaca
gataaccagctaatagtgccatcagacgggctgtacctcatctactcccaggtcctcttc
aagggccaaggatgccgttccacccatgtgctcctcacccacaccatcagccgcttcgcc
gtctcctaccagaccaaggtcaacctcctctctgccatcaagagcccttgccaaagggag
accccagaggggactgaggccaagccctggtacgagcccatctacctgggaggggtcttc
caactggagaagggtgatcgactcagcgctgagatcaacctgcctgactatctcgacttt
gccgagtccgggcaggtctactttggaatcattgccctgtga

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