Methylophaga marina: GCM100_22370
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Entry
GCM100_22370 CDS
T09183
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
mmaf
Methylophaga marina
Pathway
mmaf00270
Cysteine and methionine metabolism
mmaf00450
Selenocompound metabolism
mmaf00670
One carbon pool by folate
mmaf01100
Metabolic pathways
mmaf01110
Biosynthesis of secondary metabolites
mmaf01230
Biosynthesis of amino acids
mmaf04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
mmaf00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
GCM100_22370 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
GCM100_22370 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
GCM100_22370 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
GCM100_22370 (metH)
04980 Cobalamin transport and metabolism
GCM100_22370 (metH)
Enzymes [BR:
mmaf01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
GCM100_22370 (metH)
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Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
MtrH
Motif
Other DBs
NCBI-ProteinID:
BDZ74518
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Position
2179540..2183238
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AA seq
1232 aa
AA seq
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MTVHQQIKSLLEQRILILDGGMGTLIQSYKLEEKDFRGARFADHPCDVKGNNDLLSLTQP
QIIRDIHRAYFEAGADIVETNTFNGTSIAMADYQMEDLVYELNKVSAELAKEVADEFTAN
NPDKPRFVTGVLGPTNRTASISPDVNNPGFRNVSFDELVDAYMEAIRGLVDGGADLLLVE
TVFDTLNAKAALFAIDQFCERNGVHIPVMISGTITDASGRTLSGQTAEAFWNSLAHIQPL
SIGLNCALGAEQLRQYVEELANVVTCHISAHPNAGLPNEFGEYDESPEVMAAQIKEWAES
GFLNIVGGCCGTAPAHIKAIADAVEGIHPRQPKKNLHHCRLSGLEPLNITPDSLFVNVGE
RTNVTGSARFAKLIKEGDYDTALEVARQQVENGAQIIDINMDEGMLDSKEAMVTFLNLLA
AEPDISRVPIMIDSSKWDVIEAGLKCIQGKGIVNSISLKEGEDKFIEQAKLVRRYGAAVI
VMAFDEVGQADTRERKLEICRRSYEVLTEKVHFPPEDIIFDPNIFAVATGIEEHNNYAVD
FIEAVHDIKQSLPHALISGGVSNVSFSFRGNNPVREAIHAVFLYHAIKAGMDMGIVNAGQ
LAIYDDLPEELREAVEDVVQNRREDSTDRLLELAEKYKGEGGSVAKQEDLAWRELPVVKR
LEHALVKGIADYVEDDTEEARQQFAKPLEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSA
RVMKKAVAYLMPFIEAAKEEGDTSKNNGKILMATVKGDVHDIGKNIVGVVLQCNNFEVID
LGVMVPAQKILDTAREEKVDIIGLSGLITPSLDEMVHVAKEMERLGMETPLMIGGATTSL
IHTAVKIEPNYHGCSIYVKDASRAVGVAQRLVTKDTRDAFIADLKKDYEEKRSRHKGRKS
SRRQLSITEARANKTKIDWAAYQPTKPAKLGLEVFDDYPLAELVDRIDWTPFFQSWELAG
KYPRILTDEVVGEHATHLFEDAQKMLQQIVDEKWLTAKAVIGLFAANSVNDDDIEVYRDD
SRDEVLMTLHSLRQQTERPPGRPNAALADFIAPKDTGVNDYIGAFAVTAGIGIDEHVARF
EEDHDDYHSIMLKALADRLAEAFAERMHERVRKEFWGYAKEEQLDNDALIDEKYQGIRPA
PGYPACPDHTEKGLLWELIDPVTHADMTITESYAMLPTAAVSGFYFAHPESRYFGLGKID
QDQVEDYAERKGWDKQTAERWLGPALSYDGDD
NT seq
3699 nt
NT seq
+upstream
nt +downstream
nt
atgactgtgcatcaacaaattaaatccttacttgagcaacgtattctgattctagacggt
ggaatggggacgttgatccaaagttataaactggaagaaaaagattttcgtggtgcgcga
tttgcagatcatccctgtgatgtaaaaggcaataacgatcttttgtctttgacccagccg
caaattattcgcgatatccatcgtgcctattttgaagccggtgcggatattgttgaaacg
aacacctttaatggtacatcaattgccatggctgattaccagatggaagatctggtgtat
gagttaaataaagtctcagccgaattagctaaagaagtggctgatgaatttacggctaac
aacccagacaagccacgttttgtcaccggtgtattgggcccaactaaccgcacggccagt
atctctcctgatgtgaataatccaggctttcgaaatgtcagttttgatgaactggttgat
gcatacatggaagccattcgtggtttggttgatggcggtgctgatttgttgctggtcgaa
acggtgtttgacaccttaaatgccaaagccgccttgtttgcgattgatcagttctgcgaa
cgaaatggtgtacatatcccggtcatgatttcaggcacgattactgatgccagtggtcgt
acactttcaggccaaacggccgaagcattctggaactcgctggcgcatatccagcctctg
agtattggcctgaactgtgcactgggtgcggagcagttacgtcagtacgtggaagagtta
gccaatgtagtgacttgtcatatcagtgctcaccccaatgcaggcttacctaatgagttc
ggtgagtatgatgaatcaccagaagtcatggcagcacagattaaagaatgggctgagtct
ggtttcttaaacattgtcggtggctgttgcggtaccgcccctgctcatatcaaagcgatt
gctgatgcagtagagggtattcatcctcgtcagccaaagaagaatctacatcactgccga
ttgagtggtttagaacccctgaatatcacccctgacagtttatttgtgaatgtaggcgaa
cggaccaatgtcacgggctcggcgcgtttcgccaagctaatcaaagaaggcgactacgat
acggcactggaagtggcacgtcagcaagtagaaaacggtgctcaaatcattgacatcaat
atggatgagggcatgctggactcgaaagaggccatggtcaccttccttaacttactcgct
gctgaaccagatatcagccgtgtgcctatcatgattgactcatctaaatgggacgttatc
gaggcaggtctgaaatgtattcaaggtaaaggcattgttaactccatcagcctgaaagag
ggtgaagataaatttatcgaacaggctaaattggttcgccgttatggtgcagcggtgatt
gtaatggcctttgatgaagtcggtcaggccgatacacgtgaacgtaagctggaaatttgt
cgacgttcctatgaggtgctgacagagaaagttcatttcccaccagaagatatcatcttc
gatcccaacatctttgccgtcgccacaggtattgaagagcataataattacgccgtcgat
tttattgaggctgttcacgatattaaacaaagtctgccacatgcgctgatcagtggtggt
gtttccaacgtctcattctcattccgtggtaacaatccggtgcgtgaagcgattcatgcg
gttttcctctaccacgcgattaaagcgggcatggatatggggattgttaatgctggccag
ctggctatctatgatgatctgcctgaagaattgcgtgaagccgtagaagatgtcgtgcaa
aaccgccgtgaagattctactgaccgattgctggaactcgccgaaaaatacaaaggcgaa
ggtggcagtgtggctaagcaggaagacttggcctggcgtgagctacctgtcgtcaagcgt
cttgagcatgctttggtaaaaggcattgcggattatgttgaagacgatacagaagaagca
cgccaacaatttgccaaaccactggaagtgattgaagggccgttgatggacggtatgaac
gtggtcggtgacttgtttggtgaaggtaagatgtttttaccgcaagtggtcaaatctgcc
cgtgtaatgaaaaaagcagtcgcttatctgatgcctttcattgaagcggctaaagaagaa
ggcgataccagcaaaaataacggcaagattttgatggccaccgtcaaaggtgacgttcat
gatatcggtaaaaatatcgtgggcgtggtcctgcaatgtaataactttgaagttatagat
cttggcgtgatggtgccagcgcagaaaattctggatacggcacgcgaagaaaaagtcgat
attatcggcttgtctggtctgattacgccatcacttgatgaaatggtgcatgtcgcgaaa
gaaatggagcgactaggcatggaaactccactgatgattggtggggctaccacttcctta
atccataccgccgtgaaaattgaaccgaactatcatggctgcagtatctatgtaaaagac
gcgtcacgtgctgtgggtgtggctcagcgtttagtcaccaaagatacacgtgatgccttt
attgctgatctgaaaaaagactatgaagagaagcgttcaagacataagggacgtaagagc
agtcgacgtcaattaagtattactgaagcacgagcgaataaaaccaagattgactgggcc
gcttatcaaccaaccaaacctgctaaattgggtctggaggtgtttgatgactatcctctg
gctgaattggtggatcgcattgattggacgccttttttccaatcctgggagctggctggc
aagtacccccgtattctgaccgacgaagtggttggcgagcacgccacacatctatttgaa
gatgcacaaaaaatgttgcagcaaatcgtcgatgagaaatggctgacagccaaagcggtc
attggcctttttgcggcgaatagcgtgaatgacgatgatattgaagtgtatcgtgacgat
agccgtgatgaggtattgatgacgttgcatagcttgcgtcaacaaaccgagcgtccacct
ggtcgtccaaatgccgctttagccgattttatcgcgccaaaagatacgggcgtcaatgat
tatattggggcgtttgccgtaacggcaggcattggcattgatgagcacgttgcacgcttt
gaagaagatcatgacgactatcacagcattatgctgaaagcgctggcggatcgtctggca
gaagcctttgcagaacgcatgcatgaacgggttcgaaaagaattctggggttatgctaaa
gaagagcaattagacaatgatgccttgattgatgagaaatatcagggcattcgtccggca
ccaggttatcctgcctgtccggatcatactgagaaaggtctgttatgggagctgattgat
cctgttacccatgccgatatgaccattacagaaagttatgccatgttgccaactgccgct
gtcagtgggttctattttgcccaccctgagtcacgttattttggcttgggtaaaatcgac
caggatcaggtggaagactatgctgagcgaaaaggttgggataaacaaacagctgaacgt
tggttgggaccggcattatcttatgatggagatgactaa
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