Mycobacterium malmoense: K3U93_17990
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Entry
K3U93_17990 CDS
T07571
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mmam
Mycobacterium malmoense
Pathway
mmam00020
Citrate cycle (TCA cycle)
mmam00630
Glyoxylate and dicarboxylate metabolism
mmam00785
Lipoic acid metabolism
mmam01100
Metabolic pathways
mmam01110
Biosynthesis of secondary metabolites
mmam01120
Microbial metabolism in diverse environments
mmam01200
Carbon metabolism
mmam01210
2-Oxocarboxylic acid metabolism
Module
mmam_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mmam_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mmam00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
K3U93_17990
00630 Glyoxylate and dicarboxylate metabolism
K3U93_17990
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
K3U93_17990
Enzymes [BR:
mmam01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
K3U93_17990
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
K3U93_17990
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
K3U93_17990
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
K3U93_17990
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QZA16540
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Position
3930071..3933793
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AA seq
1240 aa
AA seq
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MSNISPFGQNEWLVEEMYRKFRDDPSSVDPSWHEFLVDYNPEPTTESAASTPATADGQAA
PQPTPAAPAPARPAAPTAKPTAATGNGAPVPSGAAPAPAAPKAATLPPAEGDELQVLRGA
AAAVVKNMSASLEVPTATSVRAVPAKLLIDNRIVINNQLKRTRGGKVSFTHILGYALVQA
IKQFPNMNRHYAEVDGKPTAITPAHTNLGLAIDLQGKDGKRSLVVAGIKRCETMRFAQFV
TAYEDIVRRARDGKLTAEDFAGVTISLTNPGTIGTVHSVPRLMAGQGAIIGVGAMEYPAE
FQGASEERIAELGIGKLITLTSTYDHRIIQGAESGDFLRTIHEMLLSDGFWDEIFRELGN
PYLPVRWSTDNPDSIVDKTARVMELIAAYRNRGHLMADIDPLRLDGTRFRSHPDLELLNH
GLTLWDLDRVFKVNGFAGCEYKKLRDVLGLLRDAYCRHIGIEYTHILEPEQQEWLQQRVE
TKHVKPTVAEQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGAESVIPMMDAAIDQCAEH
GLDEVVIAMPHRGRLNVLANIVGKPYKQIFTEFEGNLNPAQAHGSGDVKYHLGATGVYLQ
MFGDNDIQVSLTANPSHLEAVDPVLEGLVRAKQDLLALAAAAGGEESFSVVPMMLHGDAA
FAGQGVVAETLNLANLPGYRVGGTIHIIVNNQIGFTTAPEYSRSSEYCTDVAKMVGAPIF
HVNGDDPEAGVWVAKLAVDFRQRFKKDVVIDMLCYRRRGHNEGDDPSMTNPAMYDVVDVK
RGVRKSYTESLIGRGDISLKEAEDALRDYQGQLERVFNEVRELEKQSAQPSESVESDQMI
PAGLSTAVDKALLARIGDAFLAVPDGFTAHPRVQPVLERRREMAYEGKIDWAFGELLALG
SLVAEGKLVRLSGQDTRRGTFSQRHSVIFDRNTGDEFTPLQLLATNPDGSPTGGRFMVYD
SPLSEYAAVGFEYGYTVGNPDALVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSNVVL
LLPHGHEGQGPDHTSGRIERFLQLWAEGSMTIAVPSTPSNYFHLLRRHALDGIQRPLIVF
TPKSMLRNKAAVSEVKDFTEIKFRSVLEEPTYEDGIGDRGKVRRILLTSGKLYYELAARK
AKDNRDDVAIVRIEQLAPLPKRRLGETLDRYPEASEFFWVQEEPANQGAWPRFGLELPEL
LPDKLTGIKRISRRAMSAPSSGSSKVHAVEQQEIIDTAFG
NT seq
3723 nt
NT seq
+upstream
nt +downstream
nt
gtgagcaacatatcaccattcgggcaaaacgaatggctggtcgaggagatgtaccgcaag
ttccgcgacgacccctcgtcggtcgatccaagctggcacgaattcctcgtcgactacaac
cccgagccgaccaccgaatcggcggcgagcaccccggccacggccgacgggcaggccgcc
ccgcaaccgacgcccgccgcaccggcccccgcccggccggccgctcctaccgccaagccc
acggccgcgacgggcaacggcgccccggtgccgtccggggcggcaccggctccagctgca
ccgaaggccgccactctcccgccggccgagggcgacgagttgcaggtgctgcgcggcgcc
gccgcggccgtcgtcaagaacatgtccgcgtcgctggaggtgccgacggcgaccagcgtt
agggccgttccggccaagctgctgatcgacaaccggatcgtcatcaacaaccagctcaag
cgcacccgcggcggcaaggtctccttcacccacatcctgggctacgcgctggtgcaggcg
atcaagcagttcccgaacatgaaccggcactacgcggaggtcgacggcaagcccaccgcg
atcacgccggcgcacaccaatctgggcctggcgatcgacctgcagggcaaggacggcaag
cgctccctggtagtggccggcatcaagcgttgcgagaccatgcgattcgcgcagttcgtc
accgcctacgaagacatcgtgcgccgggcccgcgacggcaagctgaccgccgaagacttt
gccggcgtgacgatttcgctgaccaaccccggcaccatcggcaccgtgcactcggtgccg
cggctgatggccggccagggcgccatcatcggcgtcggcgccatggaataccccgccgag
ttccagggtgccagcgaggagcgcatcgccgagctgggcatcggcaagctgatcaccctg
acctcgacctacgaccaccgcatcatccagggcgcggaatccggcgacttcctgcgcacc
atccacgaaatgctgctctcggacggtttctgggacgagatcttccgcgagctgggcaat
ccgtacctgcccgtgcgctggagcaccgacaaccccgactcgatcgtcgacaagaccgcc
cgcgtcatggagttgatcgcggcctaccgcaaccgcgggcacctgatggccgacatcgac
ccgctgcgcctggacgggaccaggttccgcagccaccccgacctggaattgctcaaccac
ggcctgacgctgtgggacctcgaccgggtgttcaaggtcaacggcttcgccggttgcgag
tacaagaagctgcgcgacgtgctgggcctgctgcgcgacgcctactgccgccacatcggc
atcgaatacacccacatcctcgaacccgaacaacaggagtggctgcaacagcgggtcgag
accaaacacgtcaaaccgactgtggccgaacagaagtacatcctgagcaagctgaacgcc
gccgaggccttcgagaccttcctgcaaaccaaatacgttgggcagaaacggttttcgctg
gagggcgccgaaagtgtgatcccgatgatggacgcggcgatcgaccagtgcgccgagcac
ggcctcgacgaggtggtcatcgcgatgccgcaccgcggccggctcaacgtgctggccaac
atcgtcggcaagccgtacaagcagatcttcaccgagttcgagggcaacctcaacccggca
caggcgcacggctccggcgacgtcaaataccacctcggcgccaccggtgtgtacctacag
atgttcggcgacaacgacattcaggtgtcactgaccgccaacccgtcgcacctggaagcc
gtggacccggtgctggagggcctggtccgggccaagcaggacctgctggccctcgcggcc
gccgctggcggcgaagagagcttctccgtggtgccgatgatgctgcacggtgacgccgcc
ttcgccgggcagggagtggtggccgagacgctgaacctggcgaacctgcccggctaccgc
gtcggcggcaccatccacatcatcgtcaacaaccagatcggtttcaccaccgcgccggag
tactccaggtccagcgagtactgcaccgacgtcgccaagatggtcggggcgccgatcttc
cacgtcaacggtgacgacccggaagccggcgtgtgggtggcgaagctggccgtggacttc
cggcagaggttcaagaaggacgtcgtcatcgacatgctgtgctaccgccggcgcgggcac
aacgagggcgacgacccgtcgatgaccaaccccgccatgtacgacgtggtcgacgtcaag
cgcggggtccgcaagagctacaccgaatccctgatcggccgcggcgacatctcgctgaaa
gaggccgaggacgcgctgcgcgactaccagggccagctggagcgggtgttcaacgaggtc
cgcgagctggagaagcaaagcgcgcagccgagcgaatcggtcgagtccgaccagatgatc
cccgccgggctgtccaccgcggtggacaaggcgctgctggcccgcatcggcgacgcgttt
ttggccgtcccggacggtttcaccgcgcatccgcgcgtgcagccggtgctggaaaggcgc
cgcgagatggcctacgagggcaagatcgactgggccttcggcgagctgctggcgttgggt
tcgctggtggccgagggcaagctggtgcggctctccggtcaggacacccggcgcggcacc
ttctcccagcggcattcggtgatcttcgaccgcaacaccggcgacgagttcacgccgctg
caactgctggcgaccaaccccgacggcagccccaccggcggcaggttcatggtctacgac
tcgccgctgtccgagtatgcggccgtcggcttcgagtacggctacacggtgggcaacccg
gacgccctggttttgtgggaggcgcagttcggcgacttcgtcaacggcgcgcagtcgatc
atcgacgagttcatcagctccggtgaggccaagtggggccagctgtccaacgtggtgttg
ctgctgccgcacgggcacgaggggcaggggcccgaccacacctccggtcgcatcgaacgc
ttcctgcagttgtgggcggagggttcgatgacgatcgcggtgccctcgacgccgtcgaac
tacttccacctgttgcgccggcacgccctcgacggtatccagcgcccgctgatcgtgttc
accccgaagtcgatgctgcgcaacaaggcggccgtcagcgaggtcaaggacttcaccgag
atcaagttccgctcggtactggaggaacccacctacgaggacggcataggcgatcgcggc
aaggtccgcaggatcctgctgaccagcggaaagctctactacgagctggcggcgcgcaag
gctaaggacaaccgcgacgacgtcgcgatcgtgcggatcgaacagctcgccccgctgccg
aaacgccggctgggcgagacgctggaccgctatcccgaggccagcgagtttttctgggtg
caggaggagccggccaaccagggcgcgtggccgcggttcggcctggagctgcccgagctg
ctgcccgacaagctgaccgggatcaagcgcatttcgcgccgggcgatgtcggcgccgtcg
tcgggctcgtcgaaggtgcacgccgtcgagcagcaggagatcatcgacacggccttcggg
tga
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