| Entry |
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| Symbol |
metH
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| Name |
(GenBank) B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase
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| KO |
| K00548 | 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] |
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| Organism |
mmar Modestobacter italicus
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| Pathway |
| mmar01110 | Biosynthesis of secondary metabolites |
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| Module |
| mmar_M00017 | Methionine biosynthesis, aspartate => homoserine => methionine |
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| Brite |
KEGG Orthology (KO) [BR:mmar00001]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
MODMU_2592 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
MODMU_2592 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
MODMU_2592 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
MODMU_2592 (metH)
04980 Cobalamin transport and metabolism
MODMU_2592 (metH)
Enzymes [BR:mmar01000]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
MODMU_2592 (metH)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
2552645..2556460
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| AA seq |
1271 aa
MPEFSPPVPAELRPDATAALTAQLAQRILVLDGAMGTAIQRDRPDEAGYRGERFADWPTD
VQGNNDLLSITAPGIITAIHREYLEAGADLIETNTFNATRISLSDYGMSDLAYELNVASA
RLARAECDAMTARTPDKPRYVVGAIGPTSRTASISPDVNDPGARNVSYDELVAAYLEQAG
GLVDGGSDVLLIETIFDTLNAKAAVFALETLFEQRGRRWPVMISGTITDASGRTLSGQVT
EAFWHSVRHAQPLLVGLNCALGAKEMRPYIAEISRVADTFVSCYPNAGLPNAFGEYDEAP
EETAAILEEFAGAGFVNLVGGCCGTTPAHIAAIARAVEGRAPRTPVEVRPALRLSGLEPV
TIDEDSLFVNVGERTNITGSARFRNLIKAGDYPAALAVARQQVEAGAQVIDVNMDEGMID
GVAAMDRFTKLIASEPDISRVPTMIDSSKWEVIEAGLKNVQGKAIVNSISLKNGEEEFLA
HARLCRKYGAAVVVMAFDEDGQGDTLQRRTQICRRAYDLLVDQVGFPAEEIIFDPNIFAV
ATGIEEHANYGLDFIEATRWIKQNLPGALVSGGVSNVSFSFRGNNPVREAIHSVFLYHAI
AAGLDMAIVNAGQLEVYSEVPELLRDRIEDVVLNRRPDSTERLLEIAADFAGDGSVKEAA
TEEWRSLPVDERITHALVKGIDAFVEDDTEELRQQISDRGGRPIEVIEGPLMDGMNVVGD
LFGAGKMFLPQVVKSARVMKKAVAHLIPFIEAEKQPGDAERSNGKVVMATAKGDVHDIGK
NIVGVVLQCNNYDVVDLGVMVPAQRILDTAKAEGADIIGLSGLITPSLDEMVNLATEMER
QGFEVPLLVGGATTSRAHTAVKIAHKYHGPVVWVKDASRSVPVVAALLSDEQRPKLLADT
EAEYETLRERHAARNDTRSLLPLATARAQAPEIDWSSYAPPRPRMLLQQAHDVCSGPDCD
HRHGTATQFVRTFTDYPLDELRGYIDWQPFFSAWEMRGRFPDILHNPASGEAARRLFEDA
QAMLDRVVEERWLRASGVFGLFPANQVDGEDIEVYTDDSRTEVRATLHQLRQQTAGRDGS
PRKSLADFVAPSSTGLRDHVGAFAVTAGLGSAERVAQFKADHDDYNAILLESLADRLAEA
FAERLHERVRREFWGYAPDEHLDADGLIAEKYTGIRPAPGYPACPEHTEKQTIWELLDVE
AATGIQLTESMAMWPGAAVSGLYFSHPRSRYFVLGRLGRDQVEDYARRKGWTVDEAERWL
SPNLGYRTENE |
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| NT seq |
3816 nt +upstreamnt +downstreamnt
gtgcccgagttctccccgcccgtccccgccgagctccgaccggacgccaccgccgcgctc
accgcgcagctggcgcagcgcatcctggtgctggacggggcgatgggcaccgcgatccag
cgcgaccggcccgacgaggccggctaccgcggcgagcgcttcgcggactggcccaccgac
gtccagggcaacaacgacctgctcagcatcaccgcgcccgggatcatcaccgccatccac
cgcgagtacctcgaggccggcgcggacctgatcgagaccaacaccttcaacgccacccgc
atctcgctgagcgactacgggatgtccgacctcgcctacgagctgaacgtggcctcggcc
cggctggcccgcgccgagtgcgacgcgatgaccgcccgcaccccggacaagccgcgctac
gtggtcggtgcgatcggcccgaccagccggacggcgtccatctcgcccgacgtcaacgac
cccggcgcccgcaacgtcagctacgacgagctggtcgcggcctacctcgagcaggccggt
gggctggtcgacggcggctccgacgtgctgctgatcgagaccatcttcgacacgctcaac
gccaaggccgccgtcttcgcgctggagacgctgttcgagcagcgcggccgccgctggccg
gtgatgatctccggcaccatcaccgacgcgtccggccgcacgctgtccggccaggtcacc
gaggccttctggcactcggtgcggcacgcgcagccgctgctggtggggctcaactgcgcg
ctgggtgccaaggagatgcggccctacatcgcggagatctcccgggtcgccgacacgttc
gtgtcctgctacccgaacgccgggctgcccaacgccttcggcgagtacgacgaggcgccc
gaggagaccgcggccatcctggaggagttcgccggcgccgggttcgtcaacctggtcggc
ggctgctgcggcacgaccccggcgcacatcgccgcgatcgcccgggccgtcgagggcagg
gcgccgcgcaccccggtggaggtccgcccggcgctccggctgtccgggctggagccggtc
accatcgacgaggactccttgttcgtcaacgtcggtgagcgcaccaacatcaccggctcg
gcccgcttccggaacctgatcaaggccggcgactacccggccgcgctcgccgtcgcccgc
cagcaggtggaggccggcgcccaggtcatcgacgtcaacatggacgaggggatgatcgac
ggcgtcgcggcgatggaccgcttcaccaagctgatcgcctccgagcccgacatcagccgg
gtgcccacgatgatcgactcctccaagtgggaggtcatcgaggccggcctcaagaacgtc
cagggcaaggccatcgtcaactcgatctcgctgaagaacggcgaggaggagttcctcgcc
cacgcccggctgtgccgcaagtacggcgccgcggtcgtcgtgatggccttcgacgaggac
gggcagggcgacaccctccagcgccgcacccagatctgccggcgcgcctacgacctcctc
gtcgaccaggtgggcttcccggccgaggagatcatcttcgacccgaacatcttcgccgtc
gccaccggcatcgaggagcacgccaactacggcctggacttcatcgaggccacccggtgg
atcaagcagaacctgcccggcgccctggtctccggcggcgtctcgaacgtctcgttctcc
ttccgcggcaacaacccggtgcgagaggcgatccactcggtcttcctgtaccacgcgatc
gcggccgggctggacatggcgatcgtcaacgccgggcagctcgaggtctacagcgaggtc
cccgagctgctgcgcgaccggatcgaggacgtcgtcctcaaccgccgcccggacagcacc
gagcggctgctggagatcgccgccgacttcgccggcgacgggtcggtcaaggaggcggcc
accgaggagtggcggtccctgccggtcgacgagcggatcacccacgccctggtcaagggg
atcgacgcgttcgtcgaggacgacaccgaggagctgcggcagcagatcagcgaccgcggc
ggccggccgatcgaggtcatcgagggcccgctgatggacggcatgaacgtggtcggcgac
ctgttcggcgccggcaagatgttcctgccgcaggtggtcaagtccgcccgggtgatgaag
aaggccgtcgcccacctcatcccgttcatcgaggcggagaagcagcccggggacgccgag
cgcagcaacggcaaggtcgtgatggcgacggccaagggcgacgtgcacgacatcggcaag
aacatcgtcggcgtcgtcctgcagtgcaacaactacgacgtcgtcgacctgggggtcatg
gtcccggcgcagaggatcctggacaccgccaaggcggagggcgccgacatcatcgggctg
tccgggctgatcacgccgtccctggacgagatggtcaacctggccaccgagatggaacgg
cagggcttcgaggtgccgctgctcgtcggtggggcgacgacgtcgcgcgcgcacaccgcg
gtcaagatcgcgcacaagtaccacgggcccgtcgtctgggtgaaggacgcctcacggtcg
gtgccggtcgtcgcggcgctgctgtccgacgagcagcgcccgaagctgctcgccgacacc
gaggccgagtacgagacgctgcgcgagcggcacgccgcccggaacgacacccgcagcctg
ctgccgctggccaccgcccgggcccaggccccggagatcgactggagcagctacgccccg
ccgcggccgcggatgctgctgcagcaggcccacgacgtgtgcagcggaccggactgcgac
caccggcacggcacggcgacccagttcgtgcggaccttcaccgactacccgctggacgag
ctgcgcggctacatcgactggcagccgttcttctccgcctgggagatgcgcggccggttc
cccgacatcctgcacaacccggccagcggtgaggccgcccgccggctgttcgaggacgcg
caggcgatgctcgaccgggtggtcgaggagcggtggctgcgggccagcggggtgttcggg
ctgttcccggccaaccaggtcgacggcgaggacatcgaggtctacaccgacgactcgcgg
accgaggtccgggccacgctgcaccagctgcggcagcagaccgccggccgcgacggctcg
ccgcgcaagtccctcgccgacttcgtggcaccgagctccaccgggctgcgggaccacgtg
ggcgccttcgccgtcaccgccgggctgggctcggcggagcgggtcgcgcagttcaaggcc
gaccacgacgactacaacgcgatcctgctggagtcgctggccgaccggctcgcggaggcg
ttcgccgagcggctgcacgagcgggtgcgcagggagttctggggctacgcccccgacgag
cacctggacgccgacgggctcatcgcggagaagtacaccggcatccggcccgccccgggc
tacccggcctgccctgagcacaccgagaagcagacgatctgggagctcctcgacgtcgag
gccgcgaccgggatccagctgaccgagagcatggcgatgtggccgggtgcggccgtcagc
gggctgtacttctcccacccgcggtcgcggtacttcgtgctcggccggctgggccgcgac
caggtcgaggactacgcccgccgcaagggctggaccgtcgacgaggcggagcggtggctc
tccccgaacctgggctaccgcaccgagaacgaatga |
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