KEGG   MODULE: mmc_M00978
Entry
mmc_M00978        Pathway   Module                                 
Name
Ornithine-ammonia cycle
Definition
K01915 K01955+K01956 K00611 K01940 K01755 (K27542,K27545)
Diagram
mmc_M00978  Ornithine-ammonia cycle
mmc_M00978

Class
Pathway modules; Amino acid metabolism; Arginine and proline metabolism
Pathway
mmc00220  Arginine biosynthesis
mmc01100  Metabolic pathways
mmc01110  Biosynthesis of secondary metabolites
Organism
Mycobacterium sp. MCS [GN:mmc]
Gene
Mmcs_0233  glutamine synthetase, catalytic region [KO:K01915]
Mmcs_0512  Glutamate--ammonia ligase [KO:K01915]
Mmcs_0870  Glutamate--ammonia ligase [KO:K01915]
Mmcs_0993  amidinotransferase [KO:K27545]
Mmcs_2057  Glutamate--ammonia ligase [KO:K01915]
Mmcs_2366  carbamoyl-phosphate synthase small subunit [KO:K01956]
Mmcs_2367  carbamoyl-phosphate synthase large subunit [KO:K01955]
Mmcs_2754  glutamine synthetase, catalytic region [KO:K01915]
Mmcs_2965  argininosuccinate lyase [KO:K01755]
Mmcs_2966  Argininosuccinate synthase [KO:K01940]
Mmcs_2968  ornithine carbamoyltransferase [KO:K00611]
Mmcs_3320  L-glutamine synthetase [KO:K01915]
Mmcs_3328  L-glutamine synthetase [KO:K01915]
Mmcs_4892  Glutamate--ammonia ligase [KO:K01915]
Mmcs_5344  L-glutamine synthetase [KO:K01915]
Reaction
R00253  
R00575  
R01398  
R01954  
R01086  
R13308  
Compound
C00014  Ammonia
C00064  L-Glutamine
C00169  Carbamoyl phosphate
C00327  L-Citrulline
C03406  N-(L-Arginino)succinate
C00062  L-Arginine
C00011  CO2
Reference
PMID:29632414
  Authors
Zhang H, Liu Y, Nie X, Liu L, Hua Q, Zhao GP, Yang C.
  Title
The cyanobacterial ornithine-ammonia cycle involves an arginine dihydrolase.
  Journal
Nat Chem Biol 14:575-581 (2018)
DOI:10.1038/s41589-018-0038-z
KO module
M00978
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