KEGG   Methylophilus medardicus: FIU01_00815
Entry
FIU01_00815       CDS       T10472                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
mmec  Methylophilus medardicus
Pathway
mmec00270  Cysteine and methionine metabolism
mmec00450  Selenocompound metabolism
mmec00670  One carbon pool by folate
mmec01100  Metabolic pathways
mmec01110  Biosynthesis of secondary metabolites
mmec01230  Biosynthesis of amino acids
mmec04980  Cobalamin transport and metabolism
mmec04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:mmec00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    FIU01_00815 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    FIU01_00815 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    FIU01_00815 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    FIU01_00815 (metH)
   04980 Cobalamin transport and metabolism
    FIU01_00815 (metH)
Enzymes [BR:mmec01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     FIU01_00815 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding CarboxypepD_reg
Other DBs
NCBI-ProteinID: QDC43205
UniProt: A0A5B8CPM0
LinkDB
Position
179628..183416
AA seq 1262 aa
MTPLPISATERWLREALSKRILILDGAMGTMIQQYKLTEADYRGTRFQDFQGPAGERELF
VKGNNELLTLTQPQVIQEIHEKYLAAGADIIETNTFGATSVAQDDYHMAHLVYEMNVEAA
KLAKAACVKYSTPDKQRFVAGALGPTPKTASISPDVNDPAARNVSFDQLVSSYLEQIRGL
VEGGADILMVETIFDTLNCKAALFAIERFFDEQGKTWPIMISGTVTDASGRILSGQTVTA
FWHSVRHVKPLTVGLNCALGATLMRPYADELSKVADTFVCIYPNAGLPNPMSDTGFDETP
DVTSSLVKEFAESGFINIAGGCCGTTPDHINAIYTAIKDLPPRQVPTLPVTTKLSGLEPF
VIDDQSLFVNVGERTNVTGSKAFARMIINEQYEEALSVARQQVENGAQVIDINMDEGMLD
AVKAMTHFLNLVASEPDIARVPIMIDSSKWAVIEAGLKCVQGKAIVNSISMKEGETEFLR
QAKLCQRYGAAVVVMAFDETGQADTYARKIEICKRAYDMLVGMGFPPEDIIFDPNIFAVA
TGIEEHNNYAVDFIEATRWIKQNLPYARISGGVSNVSFSFRGNEPAREAIHTVFLYHAIQ
AGMTMGIVNAGMVGVYDDIPAELRECVEDVVLNRPVDPDNPLAATERMIEMAGTLVAGGK
KAEATLVWRGSPETPVPASKRLEYALVHGITDYIVADTEEVRQDIMSKGGRPIHVIEGPL
MDGMNVVGDLFGQGKMFLPQVVKSARVMKSAVAHLIPFIEEEKAAEERRTGKVAKPKGKV
VIATVKGDVHDIGKNIVSVVLQCNNFEVVNMGVMVPAAEILAMAKAENADIIGLSGLITP
SLEEMAYIAKEMQRDPHFVENQTPLLIGGATTSRAHTAVKIAPNYQGPVIYVPDASRSVS
VMQNLLSPDTRGAYLAEIQADYEKARHQHANKKGVPMLPLADARANATKVTFTGDHAPIK
PKFIGRRVFKNIDLALIAQYIDWGPFFQTWDLAGFYPAILSDEIVGDAATKVFAEAQVML
KRIIDGRWLSANGVIALLPANQVNGDDIEIYTDESRTQVALTWYGMRQQTEKPVIDGVAR
PNQCLADFVAPKGIEDYIGLFAVTAGLGMEKRLADFEKQHDDYNAIMFKSLADRFAEAFA
EYMHERVRQDFWGYAAGEALDKVALIKEQYQGIRPAPGYPACPDHTVKAQMFEVLQASEI
EMQLTDSYAMMPAAAVSGFYLAHPESRYFSVDKIGNDQVEDMAKRRNVDKAWLERWLSPN
LG
NT seq 3789 nt   +upstreamnt  +downstreamnt
atgacgccactgccgatctctgccaccgaacgttggttacgtgaagcgctttccaagcgc
attctgatactcgatggtgcgatgggaaccatgatccagcaatacaagctgaccgaggcc
gattatcgtggcacgcggtttcaggactttcagggtcctgccggtgagcgcgagttattc
gtcaaaggcaacaatgagttgctcacactgacgcagccacaggtgattcaggaaattcac
gaaaaatatctggcagcaggcgcagacatcatcgaaaccaatacttttggcgccaccagc
gtggcccaagacgattatcacatggcacatttggtgtatgagatgaacgtcgaagccgcc
aagctggccaaggctgcctgtgtcaaatacagcacgccggacaagcagcgatttgtggca
ggggcattgggccccacgcccaaaaccgcctcgatttcacccgatgtgaatgaccccgca
gcgcgtaacgtgagttttgatcagttggtgagcagttatctggagcagatccgcggtttg
gtagaaggcggtgctgatatcctcatggtcgaaaccattttcgacacgctcaactgtaaa
gccgcgctgtttgccattgagcgcttttttgatgagcaaggcaaaacttggccaatcatg
atctcaggcacggtgaccgatgcctccgggcgtatcttgtccggccagaccgtcactgcc
ttctggcattccgtgcgccatgtcaaaccgctcactgtgggcctcaactgcgccctcggc
gccaccctgatgcgcccttatgctgacgaactcagcaaagtggcggataccttcgtctgc
atttaccccaacgccggtttgccgaatccgatgtcggataccggctttgatgaaacgccg
gatgtgacttctagcctggtcaaagagtttgcagaaagcggctttattaacattgcgggc
ggctgttgcggcaccacgccagaccatatcaacgcgatctacaccgcgatcaaagacctg
ccaccgcgtcaggtgccgacactgccagtgaccaccaagctgtctggtctggagccattt
gtcatcgacgatcaatccttgttcgtcaatgtgggggagcgtaccaacgtcactggctcc
aaagcgtttgcgcgcatgattatcaatgagcaatatgaagaagcgctgagtgtggcgaga
cagcaggttgaaaacggcgcgcaggtcatcgacatcaacatggatgaaggcatgctggat
gcggtcaaggccatgacgcactttttgaatctggtcgcctcagagcccgatattgcgcgc
gtgccgatcatgatcgactcctctaaatgggcggtgatcgaggccggcctgaaatgcgtg
cagggcaaagcaatcgttaactcgatctcgatgaaagagggcgaaacagaatttttacgc
caggccaaactatgtcaacgctacggcgccgccgtggtggtgatggcgtttgatgaaacc
ggtcaggcagatacctatgcgcgcaaaatcgaaatttgtaagcgcgcctatgacatgctg
gtgggcatgggctttccgcccgaagatatcatttttgatccgaatatttttgcggtcgcc
accggcatcgaagagcacaacaattatgcggtcgattttattgaggcgacgcgttggatc
aagcaaaatctgccgtatgcccgtatttctggcggcgtctccaacgttagtttcagcttc
cgcggtaatgaacccgcccgtgaggcgatacacaccgtattcctttaccacgccattcaa
gcaggcatgaccatgggcatcgtcaacgccggcatggtcggtgtgtatgacgatattccc
gccgagttacgtgagtgtgtagaagacgtggtgctcaatcgcccggtggaccctgacaat
ccactggctgcgaccgagcgcatgatcgaaatggccggtacgctggtggcggggggcaaa
aaagccgaggcgacgctcgtctggcgcggcagccctgagacgccagtgcctgcgagcaag
cgcctagaatatgcgctggtgcatggcattaccgactacatcgtcgccgataccgaagag
gtccgtcaggacatcatgagcaagggcggtcgccccatccacgtcattgaaggcccgctc
atggatggcatgaacgtggtgggtgacttgtttggccaaggcaaaatgttcttgccgcaa
gtggtcaaatcggcacgggtgatgaaatctgccgtcgcgcatctgatcccatttattgaa
gaagaaaaggccgctgaagagcgccgcacgggcaaagttgctaagcccaaaggcaaggta
gtgattgccacggttaaaggcgatgtgcacgatatcggcaaaaacatcgtctcagtggtg
ttgcaatgcaacaactttgaagtggtgaacatgggggtgatggtgccggcggcggagatt
ctagccatggccaaagccgaaaacgccgatatcatcggcttgagtgggctcattacgccc
tcactcgaagaaatggcttatatcgccaaagaaatgcagcgcgacccgcattttgtcgaa
aaccaaacgcctttactgattggtggggcgaccacttcacgcgcacacacggcggtcaaa
atagcccccaactatcagggcccggtgatttatgtgcctgatgcctcgcgctcggtcagt
gtgatgcaaaatctgctctcacccgacacccgtggcgcctatctggccgagattcaggcc
gattatgaaaaagcccgccatcagcatgccaacaaaaaaggcgtgcccatgctaccgctg
gccgatgcgcgcgctaacgcgacaaaggtcacgtttacgggggaccacgcgcccattaag
ccgaagttcatcggacgtcgcgtgtttaaaaatatcgacctcgccttaatcgcgcaatac
atcgactggggcccgtttttccagacctgggatctggccggcttttatcccgccatcctc
agcgatgagatcgtcggcgacgcagccaccaaagtgtttgccgaggcgcaagtcatgctc
aaacgcatcattgatggtcgctggctgtccgccaacggcgtgatcgccttgttgcctgcc
aaccaggtcaacggtgacgatatcgaaatttataccgatgagtcgcgcacgcaggttgcg
ctcacttggtatggcatgcgtcagcaaaccgaaaaaccagtgattgacggcgtggcgcgt
cccaatcagtgtctggctgactttgttgcgccgaaaggcattgaggattacatcggcctg
tttgctgtgaccgcagggctcggcatggaaaaacgcctggccgactttgaaaaacagcac
gatgactacaatgccattatgtttaagtctctggccgaccgctttgctgaagcctttgca
gaatacatgcatgagcgcgtgcgccaagacttttggggctatgccgcaggtgaagcctta
gacaaagttgcgttaatcaaagagcagtatcaaggtatccgacccgcaccgggctacccg
gcatgtccggaccatacggtcaaagcacaaatgtttgaggtgctacaggctagcgaaatt
gagatgcaactcaccgacagctatgccatgatgcctgcggcagctgtcagcggcttctac
cttgcgcaccctgagtcacgctattttagtgtggataaaatcggcaatgaccaggtggaa
gacatggcaaaacggcgcaatgttgataaggcttggttggagcggtggttatcgcctaac
cttgggtaa

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