Mercenaria mercenaria (northern quahog): 123552007
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Entry
123552007 CDS
T07835
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2-like isoform X1
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
mmer
Mercenaria mercenaria (northern quahog)
Pathway
mmer01100
Metabolic pathways
Module
mmer_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
mmer_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
Enzymes [BR:
mmer01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
123552007
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
123552007
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Gene cluster
GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
NAD_binding_4
Polysacc_synt_2
RmlD_sub_bind
NAD_binding_10
GDP_Man_Dehyd
NmrA
KR
Ldh_1_N
DUF6976
Motif
Other DBs
NCBI-GeneID:
123552007
NCBI-ProteinID:
XP_045197290
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All DBs
Position
4:67023847..67028978
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AA seq
367 aa
AA seq
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MKTHGTVVLVTGASGFLGQHVVKMLQTRADHVQEIRIVDVVPFINKLDYREEKPVQVTVG
SIADAQWLYEVCRGVDCVMHLASCIDISLFPNKEKSYKINVDGTRNIVDACRKCNVPRLI
YCSSIEVVRGKDHIYNGTENNTSPPDHFLFKVYGYTKKQAEDLVIQANCPKLSTICLRPS
SMYGELEPRLIQNVAGSWLGRKTRYFMTVNCGNVQADQSYVGNCAWAFVCADRTLQKSRS
NSAAGNAYFIRDDTPHANITELIVPIAEEAGFKHVPLQIPVWLLAFVVFLTYHILKIVSV
VYPVNLQIGTDAVYSLKKVCHLSYNKARQLLDYHPIYNFQETKRFTAAYLTKIKNEYSNQ
CSEGKNT
NT seq
1104 nt
NT seq
+upstream
nt +downstream
nt
atgaagactcatggtacagttgttcttgtcacaggagcatcgggatttctcggacaacat
gttgtaaagatgttacagacacgtgcagaccacgtgcaggaaattaggatagtagatgtt
gtcccttttataaataagttggattatagagaagagaaacccgtgcaagtcactgttggc
agcatcgctgacgctcaatggctgtatgaggtgtgtcgcggcgtggactgtgtaatgcac
ctagctagctgcattgatatatctctgttcccaaataaagaaaagtcgtacaaaatcaac
gtagacggaactcgaaatatagttgatgcctgtcgtaaatgcaatgttcctagactaata
tactgcagcagtatcgaggtagttaggggcaaagaccacatatacaatggcacggaaaat
aacacctctccacctgatcacttccttttcaaggtgtacggatatacaaagaaacaagca
gaggacttggtaattcaggcaaattgtccaaaattgtcaacaatttgccttcggccttct
agtatgtatggagaacttgaaccacgcttaattcaaaatgtagcaggcagctggttgggc
agaaaaacaagatattttatgactgtaaactgtggtaacgttcaggctgaccagtcttac
gttggaaactgtgcttgggctttcgtttgtgctgatcggacattgcagaagtcgaggtca
aattcagcagccgggaatgcttatttcattcgggatgatacgccacatgcaaatattaca
gaactaattgtaccaattgctgaagaagcaggatttaaacatgttccattgcaaatacct
gtctggttactcgcgtttgtagtatttttgacgtatcatattttaaaaatagtctctgtg
gtatatcccgttaatcttcagattggtacagacgccgtttatagtttaaaaaaggtatgc
catctcagctataataaagccagacaattgttagattaccatccaatctacaacttccag
gaaacgaaacgttttactgcagcttacctcacgaaaataaaaaatgaatattcaaatcaa
tgttctgaaggaaagaatacttaa
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