KEGG   Molossus molossus (Pallas's mastiff bat): 118631528
Entry
118631528         CDS       T07221                                 
Symbol
ADCY8
Name
(RefSeq) adenylate cyclase type 8 isoform X1
  KO
K08048  adenylate cyclase 8 [EC:4.6.1.1]
Organism
mmf  Molossus molossus (Pallas's mastiff bat)
Pathway
mmf00230  Purine metabolism
mmf01100  Metabolic pathways
mmf01522  Endocrine resistance
mmf04015  Rap1 signaling pathway
mmf04020  Calcium signaling pathway
mmf04022  cGMP-PKG signaling pathway
mmf04024  cAMP signaling pathway
mmf04062  Chemokine signaling pathway
mmf04072  Phospholipase D signaling pathway
mmf04081  Hormone signaling
mmf04082  Neuroactive ligand signaling
mmf04114  Oocyte meiosis
mmf04211  Longevity regulating pathway
mmf04213  Longevity regulating pathway - multiple species
mmf04261  Adrenergic signaling in cardiomyocytes
mmf04270  Vascular smooth muscle contraction
mmf04371  Apelin signaling pathway
mmf04540  Gap junction
mmf04611  Platelet activation
mmf04713  Circadian entrainment
mmf04714  Thermogenesis
mmf04720  Long-term potentiation
mmf04723  Retrograde endocannabinoid signaling
mmf04724  Glutamatergic synapse
mmf04725  Cholinergic synapse
mmf04727  GABAergic synapse
mmf04742  Taste transduction
mmf04750  Inflammatory mediator regulation of TRP channels
mmf04911  Insulin secretion
mmf04912  GnRH signaling pathway
mmf04913  Ovarian steroidogenesis
mmf04914  Progesterone-mediated oocyte maturation
mmf04915  Estrogen signaling pathway
mmf04916  Melanogenesis
mmf04918  Thyroid hormone synthesis
mmf04921  Oxytocin signaling pathway
mmf04923  Regulation of lipolysis in adipocytes
mmf04925  Aldosterone synthesis and secretion
mmf04926  Relaxin signaling pathway
mmf04927  Cortisol synthesis and secretion
mmf04928  Parathyroid hormone synthesis, secretion and action
mmf04934  Cushing syndrome
mmf04935  Growth hormone synthesis, secretion and action
mmf04970  Salivary secretion
mmf04971  Gastric acid secretion
mmf04972  Pancreatic secretion
mmf04976  Bile secretion
mmf05032  Morphine addiction
mmf05163  Human cytomegalovirus infection
mmf05166  Human T-cell leukemia virus 1 infection
mmf05200  Pathways in cancer
mmf05207  Chemical carcinogenesis - receptor activation
mmf05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mmf00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    118631528 (ADCY8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    118631528 (ADCY8)
   04371 Apelin signaling pathway
    118631528 (ADCY8)
   04020 Calcium signaling pathway
    118631528 (ADCY8)
   04072 Phospholipase D signaling pathway
    118631528 (ADCY8)
   04024 cAMP signaling pathway
    118631528 (ADCY8)
   04022 cGMP-PKG signaling pathway
    118631528 (ADCY8)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    118631528 (ADCY8)
   04081 Hormone signaling
    118631528 (ADCY8)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    118631528 (ADCY8)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    118631528 (ADCY8)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    118631528 (ADCY8)
   04062 Chemokine signaling pathway
    118631528 (ADCY8)
  09152 Endocrine system
   04911 Insulin secretion
    118631528 (ADCY8)
   04923 Regulation of lipolysis in adipocytes
    118631528 (ADCY8)
   04912 GnRH signaling pathway
    118631528 (ADCY8)
   04913 Ovarian steroidogenesis
    118631528 (ADCY8)
   04915 Estrogen signaling pathway
    118631528 (ADCY8)
   04914 Progesterone-mediated oocyte maturation
    118631528 (ADCY8)
   04921 Oxytocin signaling pathway
    118631528 (ADCY8)
   04926 Relaxin signaling pathway
    118631528 (ADCY8)
   04935 Growth hormone synthesis, secretion and action
    118631528 (ADCY8)
   04918 Thyroid hormone synthesis
    118631528 (ADCY8)
   04928 Parathyroid hormone synthesis, secretion and action
    118631528 (ADCY8)
   04916 Melanogenesis
    118631528 (ADCY8)
   04925 Aldosterone synthesis and secretion
    118631528 (ADCY8)
   04927 Cortisol synthesis and secretion
    118631528 (ADCY8)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    118631528 (ADCY8)
   04270 Vascular smooth muscle contraction
    118631528 (ADCY8)
  09154 Digestive system
   04970 Salivary secretion
    118631528 (ADCY8)
   04971 Gastric acid secretion
    118631528 (ADCY8)
   04972 Pancreatic secretion
    118631528 (ADCY8)
   04976 Bile secretion
    118631528 (ADCY8)
  09156 Nervous system
   04724 Glutamatergic synapse
    118631528 (ADCY8)
   04727 GABAergic synapse
    118631528 (ADCY8)
   04725 Cholinergic synapse
    118631528 (ADCY8)
   04720 Long-term potentiation
    118631528 (ADCY8)
   04723 Retrograde endocannabinoid signaling
    118631528 (ADCY8)
  09157 Sensory system
   04742 Taste transduction
    118631528 (ADCY8)
   04750 Inflammatory mediator regulation of TRP channels
    118631528 (ADCY8)
  09149 Aging
   04211 Longevity regulating pathway
    118631528 (ADCY8)
   04213 Longevity regulating pathway - multiple species
    118631528 (ADCY8)
  09159 Environmental adaptation
   04713 Circadian entrainment
    118631528 (ADCY8)
   04714 Thermogenesis
    118631528 (ADCY8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118631528 (ADCY8)
   05207 Chemical carcinogenesis - receptor activation
    118631528 (ADCY8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    118631528 (ADCY8)
   05163 Human cytomegalovirus infection
    118631528 (ADCY8)
  09165 Substance dependence
   05032 Morphine addiction
    118631528 (ADCY8)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    118631528 (ADCY8)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    118631528 (ADCY8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    118631528 (ADCY8)
Enzymes [BR:mmf01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     118631528 (ADCY8)
SSDB
Motif
Pfam: Guanylate_cyc AC_N Adcy_cons_dom TBK1_ULD
Other DBs
NCBI-GeneID: 118631528
NCBI-ProteinID: XP_036119843
LinkDB
Position
Unknown
AA seq 1250 aa
MELSEVRCLSGSEELYTIHPTPPAGDGGSGSRPQRLLWQTAVRHITEQRFIHGHRGSGGG
GSGGSGKGSDPAGGGPNHHASQLSGDSALPLYSLGPGERAHSTGGTKVFPERSGSGSASG
SGGGGDLGFLHLDCAPSNSDFFLSGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRK
SEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHA
YLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLATS
LLQVVLQVVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEAR
LRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADV
KGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAH
CCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKL
ESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLSLPED
IVKESVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHV
QSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAF
IVLLFITAIQSLLPSSRAMPMAIQFSILIMLHSALVLITTAEDYKCLPLVLRKTCCWINE
TYLARNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTG
VLAMVTCAVFLRLNSVLKLAVLLIMTAVYALLTETIYAGLFLRYDKLNHSGQDFLGTKEA
SLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVA
RHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDE
LLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKH
SFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLIL
KDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLV
QSLNRQRQKQLLNENNNTGIIKGHYNRRTLLTPGGSEPGTQAEGTKSDLP
NT seq 3753 nt   +upstreamnt  +downstreamnt
atggagctctccgaggtgcgctgccttagcggcagcgaggaactctacaccattcacccg
acgcccccggccggcgacggcgggagcggctctcgaccgcagcggctgctgtggcagact
gcggtgcggcacatcaccgagcagcgcttcatccacggccaccgggggagcggcggcggc
gggagcggaggctctggcaaaggctcggaccctgcaggcggcggccccaaccaccacgcg
tcgcagctgtccggcgactccgcgctgcccctctactcgctgggccctggggagagagcg
cacagcacgggtggcaccaaagtcttcccggaacgcagcgggagtggcagtgccagcggc
agcgggggagggggcgacctgggcttcttgcacctggactgcgccccgagcaactcggac
ttcttcctcagtgggggctacagctaccggggggtcattttccccacgctgcgcaactcc
ttcaagtcccgggatctggagcgcctctaccagcgctacttcctgggccagaggcgcaaa
tccgaggtggtgatgaacgtgctggacgtgctgaccaaactcaccctcttggttctccac
ttgagcctggcctcggcccccatggatcccctcaagggcatcctgctgggcttcttcacc
ggcatcgaggtggtgatctgcgctctggtggttgttaggaaggacaccacctcgcatgcg
tacctgcagtacagcggtgtggtcacctgggtggccatgaccacccagatcctggcagca
ggccttggctatgggctcctgggcgatggcattggctacgtgctcttcacgctctttgcc
acctacagcatgctgccgctgccgctcacctgggccatcctagccggcctggccacctcg
ctgctgcaggtggtcctccaagtggtcattcccagactggcggtcatttccataaaccag
gtggtggcccaggcagtgctcttcatgtgcatgaacacggccggcatcttcatcagttac
ctgtcagaccgcgcccagcgccaggccttcctggagacgcggaggtgtgtggaggcccgg
ctgcgtctggagacggaaaaccagagacaggagcggctcgtgctgtctgtgctcccccga
tttgtcgtcctggaaatgattaatgacatgaccaacgtggaggatgagcacctgcagcac
cagttccatcggatctacatccatcgctatgagaatgtcagtattctttttgcagatgtt
aaaggatttaccaacctctccacgaccttgtctgctcaggagctggtcaggatgctcaac
gagctttttgccagattcgatcgactggcccatgagcatcactgtctccgcatcaaaatc
ctgggggactgctactactgcgtttccggactccccgagccccgccaggaccacgcccac
tgctgcgttgaaatgggtctcagcatgatcaaaaccatcaggtacgtgcggtcgaggacg
aagcatgacgttgacatgcgaatcggaatccactcgggctcggtgttgtgcggcgtgctg
ggcctgcggaagtggcagtttgacgtctggtcttgggacgtggacatcgcgaacaaactt
gaatctggagggatcccggggaggattcacatttccaaagccacgctcgactgcctcaac
ggcgactataacgtggaagagggccacgggaaggagaggaacgaattcctgaggaagcat
aatatagagacctacttaattaagcagcctgaggagagtctgctgtccttgcccgaagac
attgtcaaggagtcagtgagctcctcagacaggaggaacagtggggcaacgttcacggaa
gggtcctggagccccgaactgccctttgacaacatagtggggaaacagaacactctggct
gccctaacaagaaattcaataaatctacttccaaaccatcttgcacaagctttgcatgtc
cagtctgggcctgaggaaattaacaagcgaatagaacataccatcgacttgcggagtggc
gataaattgagaagagagcatatcaagccattctcactgatgtttaaagactccagcctg
gagcacaagtattctcaaatgagggacgaagtgttcaagtcaaacttggtctgtgcattt
atcgttctcctgtttatcacggcaattcaaagtctgcttccttcttcaagggctatgccc
atggccatccagttctccatcctgatcatgctgcactcggccctggtcctcatcaccacg
gctgaggattacaagtgtctgcccctcgtgctccggaaaacttgctgttggatcaacgag
acctacttggcccggaacgtcatcatcttcgcgtccatcctgattaacttcctgggcgcc
atcctcaatatcctgtggtgtgattttgacaagtcgatacccttgaagaacctgactttc
aattcctcagctgtgtttacagatatctgctcctacccagagtacttcgtcttcacgggg
gtgttggccatggtgacctgtgcggtgttcctccgactgaactcggtgctgaagctggct
gtgctgctcattatgacggccgtctacgccctgctcaccgagaccatctacgcaggcctc
ttcctgcgctacgacaagctgaaccacagtggacaagatttcctggggaccaaggaggca
tcgctgctgctgatggccatgttcctccttgctgtgttctaccatggacagcagctggag
tacacagcccgcctggacttcctgtggcgcgttcaggccaaagaggaaatcaacgagatg
aaggagctgcgggagcacaatgagaacatgctgcggaacatcttacccagccacgtggcc
cgccacttcctggagaaggaccgagacaacgaggagctgtattctcagtcctatgacgcc
gttggggtgatgttcgcctccatcccggggttcgcggacttctactcccagaccgaaatg
aataaccaaggagtggagtgcctgcgcctgctgaacgagatcattgccgacttcgacgag
ctgctcggtgaagaccgcttccaagacattgaaaagatcaagaccattggcagcacctac
atggctgtctcgggcctgtcacctgaaaagcagcaatgcgaggacaagtggggacatctg
tgcgccctggccgacttctcgctcgccctgacggaaagcatccaggagatcaacaagcat
tccttcaacaacttcgaactccggattggcatcagccacggctcggtggtagccggcgtc
atcggcgctaagaaaccacagtacgacatctggggcaaaaccgtgaacctggccagccga
atggacagcacgggggtcagcggccggatccaagtcccagaggagacctatctcatcctg
aaggaccagggctttgcctttgactaccgcggggagatctacgtgaagggcatcagtgaa
caggaagggaaaatcaaaacgtactttctgctgggaagagtccagcccaaccccttcatc
ttgcccccgagaaggctgccggggcagtactccttggccgctgtcgtgctgggcctcgtg
cagtccctcaaccggcaaaggcagaagcagctgctcaacgagaacaacaacacaggcatc
atcaagggccactacaaccggcggactctgttgacacccggcgggtcagagcctggcacc
caagccgagggcaccaagtccgatttgccataa

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