KEGG   Molossus molossus (Pallas's mastiff bat): 118632142
Entry
118632142         CDS       T07221                                 
Symbol
PTEN
Name
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1
  KO
K01110  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
Organism
mmf  Molossus molossus (Pallas's mastiff bat)
Pathway
mmf00562  Inositol phosphate metabolism
mmf01100  Metabolic pathways
mmf01521  EGFR tyrosine kinase inhibitor resistance
mmf04068  FoxO signaling pathway
mmf04070  Phosphatidylinositol signaling system
mmf04071  Sphingolipid signaling pathway
mmf04115  p53 signaling pathway
mmf04140  Autophagy - animal
mmf04150  mTOR signaling pathway
mmf04151  PI3K-Akt signaling pathway
mmf04218  Cellular senescence
mmf04510  Focal adhesion
mmf04931  Insulin resistance
mmf05165  Human papillomavirus infection
mmf05166  Human T-cell leukemia virus 1 infection
mmf05200  Pathways in cancer
mmf05206  MicroRNAs in cancer
mmf05208  Chemical carcinogenesis - reactive oxygen species
mmf05213  Endometrial cancer
mmf05214  Glioma
mmf05215  Prostate cancer
mmf05218  Melanoma
mmf05222  Small cell lung cancer
mmf05224  Breast cancer
mmf05225  Hepatocellular carcinoma
mmf05230  Central carbon metabolism in cancer
mmf05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mmf05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mmf00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    118632142 (PTEN)
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    118632142 (PTEN)
   04070 Phosphatidylinositol signaling system
    118632142 (PTEN)
   04071 Sphingolipid signaling pathway
    118632142 (PTEN)
   04151 PI3K-Akt signaling pathway
    118632142 (PTEN)
   04150 mTOR signaling pathway
    118632142 (PTEN)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    118632142 (PTEN)
  09143 Cell growth and death
   04115 p53 signaling pathway
    118632142 (PTEN)
   04218 Cellular senescence
    118632142 (PTEN)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    118632142 (PTEN)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118632142 (PTEN)
   05206 MicroRNAs in cancer
    118632142 (PTEN)
   05208 Chemical carcinogenesis - reactive oxygen species
    118632142 (PTEN)
   05230 Central carbon metabolism in cancer
    118632142 (PTEN)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    118632142 (PTEN)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    118632142 (PTEN)
   05214 Glioma
    118632142 (PTEN)
   05218 Melanoma
    118632142 (PTEN)
   05215 Prostate cancer
    118632142 (PTEN)
   05213 Endometrial cancer
    118632142 (PTEN)
   05224 Breast cancer
    118632142 (PTEN)
   05222 Small cell lung cancer
    118632142 (PTEN)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    118632142 (PTEN)
   05165 Human papillomavirus infection
    118632142 (PTEN)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    118632142 (PTEN)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    118632142 (PTEN)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    118632142 (PTEN)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mmf01009]
    118632142 (PTEN)
Enzymes [BR:mmf01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     118632142 (PTEN)
    3.1.3.48  protein-tyrosine-phosphatase
     118632142 (PTEN)
    3.1.3.67  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
     118632142 (PTEN)
Protein phosphatases and associated proteins [BR:mmf01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   Phosphatase and Tensin homologs (PTEN)
    118632142 (PTEN)
SSDB
Motif
Pfam: PTEN_C2 Tc-R-P PTP-SAK DSPc PTP-NADK Y_phosphatase PTPlike_phytase Y_phosphatase3
Other DBs
NCBI-GeneID: 118632142
NCBI-ProteinID: XP_036120814
LinkDB
Position
Unknown
AA seq 417 aa
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK
HKNHYKIYNLLLHLLSTPVYISGSGCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFC
EDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKG
VTIPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPHFVVCQLKVKIY
SSSSGPTRREDKSMYFEFPQPLPVCGDIKVEFFHKQNKLKKDKMFHFWVNTFFIPGPEET
SERVENGSLCDQETDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLY
FTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
NT seq 1254 nt   +upstreamnt  +downstreamnt
atgacagccatcatcaaagagatcgtcagcagaaacaaaaggagatatcaagaggatgga
ttcgacttagacttgacctatatttatccaaacattattgctatggggtttcctgcagaa
agacttgaaggtgtatacaggaacaatattgatgatgtagtaaggtttttggattcaaag
cataaaaaccattacaagatatacaatcttcttcttcacctgctttctacccctgtttat
atttctggctctggatgtgctgaaagacattatgataccgccaaatttaactgcagagtt
gcacagtatccttttgaagaccataatccaccacaactagaacttatcaaacccttttgt
gaagatcttgaccaatggctaagtgaagatgacaatcatgttgcagcaattcactgtaaa
gctggaaagggacgaactggtgtaatgatttgtgcatatttgttacatcggggtaaattt
ttaaaggcacaagaggccctagatttctatggggaagtaaggaccagagataaaaaggga
gtaactattcccagtcagaggcgctatgtgtattactatagctacctgttaaagaatcat
ctggattatagaccagtggcactgttgtttcacaagatgatgtttgaaactattccaatg
ttcagtggcggaacctgcaatcctcattttgtggtctgccagctgaaggtgaagatatac
tcctccagctcaggacccacgcgacgggaggacaagtccatgtactttgagttccctcag
ccgttgcctgtgtgtggtgacatcaaagtagagttcttccacaaacagaacaagctaaaa
aaggacaaaatgtttcatttttgggtaaatacattcttcataccaggaccagaggaaacc
tcagaaagagtagaaaatggaagtctatgtgatcaagaaactgatagtatttgcagtata
gagcgagcagataatgacaaggaatatctagtactcactttaacaaaaaatgatctcgac
aaagcaaataaagacaaggccaatcgatacttttctccaaattttaaggtgaagctgtat
ttcacaaaaacagtagaggagccatcaaatccagaggctagcagttcaacttctgtaacg
ccagatgttagtgacaatgaacctgatcattataggtattctgacaccactgactctgat
ccagagaacgaaccttttgatgaagatcagcatacacagattacaaaagtctga

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